Above and Beyond Glycemic Control: Reducing the Risk of Cardiovascular Disease - CME Information

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<li class="first"> <a class="" href="/web/20130908165151/http://www.healio.com/endocrinology/education-lab" title="News" target=""> Education Lab Home</a> </li> <li class="active"> <a class="" href="/web/20130908165151/http://www.healio.com/endocrinology/education-lab?selection=0" title="News" target=""> CME</a> </li> </ul> </li> <li><a href="/web/20130908165151/http://www.healio.com/endocrinology/books" title="Books" target=""> Books</a> <ul class="sub_menu"> </ul> </li> <li><a href="/web/20130908165151/http://www.healio.com/endocrinology/meetings" title="Meetings" target=""> Meetings</a> <ul class="sub_menu"> <li class="first"> <a class="all" href="/web/20130908165151/http://www.healio.com/endocrinology/meetings" title="News" target=""> Meetings/Courses</a> </li> <li class="first"> <a class="all" href="/web/20130908165151/http://www.healio.com/endocrinology/meetings/meeting-news-coverage" title="News" target=""> Meeting News Coverage</a> </li> </ul> </li> <li><a 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<span class="earn-cme-btn"><a id="layout_0_maincontent_0_ctl00_EarnCMECreditLink" href="/web/20130908165151/http://www.healio.com/endocrinology/education-lab/2013/04_april/glycemic-control-reducing-the-risk-of-cardiovascular-disease/posttest">Earn CME Credit »</a></span> </li> <li> <table cellspacing="0" cellpadding="0" border="0" width="650" style=""> <tbody> <tr> <td colspan="2"> <strong>Author(s)/Faculty: </strong> R. Scott Wright, MD; A. Michael Lincoff, MD; Jorge Plutzky, MD </td> </tr> <tr> <td colspan="2"> <strong>Source: </strong> Healio - Endocrinology Education Lab </td> </tr> <tr> <td width="195"> <strong>Type: </strong> Monograph </td> <td width="195"> <strong>Articles/Items: </strong> 5 </td> </tr> <tr> <td width="195"> <strong>Release Date: </strong> 3/1/2013 </td> <td width="195"> <strong>Expiration Date: </strong> 3/31/2014 </td> </tr> <tr> <td width="195"> <strong>Credit Type: </strong> CME </td> <td width="195"> <strong>Number of Credit(s): </strong> 1.25 </td> </tr> <tr> <td width="195" class="last"> <strong>Cost: </strong> Free </td> <td width="195" class="last"> Provider: <img src="/web/20130908165151im_/http://www.healio.com/~/media/Images/Education Lab/Provider Logos/VindicoLogo4web.gif" alt="Vindico Medical Education" width="77" height="19"/> </td> </tr> </tbody> </table> </li> <li class="overview" style="">Although microvascular complications of type 2 diabetes are reduced with intensive glycemic control, treatment of hyperglycemia has not been consistently shown to affect macrovascular complications, such as coronary artery, cerebrovascular and peripheral vascular disease. Preventive efforts have accordingly shifted toward modifi cation of other cardiovascular risk factors in patients with diabetes. Current therapeutics available for diabetes management do not inhibit the associated secondary cardiovascular complications. Hence, the development of multimodal drugs, which can reduce hyperglycemia and concomitantly inhibit the progression of secondary cardiovascular complications, may offer a valuable therapeutic option. Over the last decade, the members of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors have emerged as valuable pharmacologic targets whose activation can normalize metabolic dysfunctions and reduce some cardiovascular risk factors associated with diabetes. This monograph discusses currently available therapeutics and future treatments for patients with diabetes.</li> <li class="sponsor">This activity is supported by an educationl grant from Genentech.</li> </ul> <script type="text/javascript"> </script> <div class="cme-tab-group"> <ul id="layout_0_maincontent_1_ctl00_tabs" class="cme-tabs"><li><a class="current" href="javascript:void(0)">CME Information</a></li> <li><a class="disabled" href="javascript:void(0)">Pretest</a></li> <li><a href="/web/20130908165151/http://www.healio.com/endocrinology/education-lab/2013/04_april/glycemic-control-reducing-the-risk-of-cardiovascular-disease/introduction">Introduction</a></li> <li><a href="/web/20130908165151/http://www.healio.com/endocrinology/education-lab/2013/04_april/glycemic-control-reducing-the-risk-of-cardiovascular-disease/mechanisms-of-macrovascular-disease-in-t2-diabetes">Mechanisms of Macrovascular Disease in T2 Diabetes</a></li> <li><a href="/web/20130908165151/http://www.healio.com/endocrinology/education-lab/2013/04_april/glycemic-control-reducing-the-risk-of-cardiovascular-disease/reducing-major-cardiovascular-events-in-t2-diabetes">Reducing Major Cardiovascular Events in T2 Diabetes</a></li> <li><a href="/web/20130908165151/http://www.healio.com/endocrinology/education-lab/2013/04_april/glycemic-control-reducing-the-risk-of-cardiovascular-disease/current-and-future-therapeutics-to-reduce-cardiovascular-risk">Current and Future Therapeutics to Reduce Cardiovascular Risk</a></li> <li><a href="/web/20130908165151/http://www.healio.com/endocrinology/education-lab/2013/04_april/glycemic-control-reducing-the-risk-of-cardiovascular-disease/posttest">Posttest</a></li> <li><a class="disabled" href="javascript:void(0)">Evaluation</a></li> </ul> </div> <div class="top-btnbox"><div class="earn-cme-btn"><a href="/web/20130908165151/http://www.healio.com/endocrinology/education-lab/2013/04_april/glycemic-control-reducing-the-risk-of-cardiovascular-disease/posttest"></a></div><span class="login-note">You must be logged in to Healio.com to see this activity.</span><input type="submit" name="layout_0$maincontent_2$ctl10" value="" class="btnNext" align="right" style="margin:1px 0;"/></div> <a name="content"></a><div class="content"><p><span style="text-decoration: underline;"><strong>Sponsorship Statement:</strong></span> This continuing medical education activity is sponsored by <img width="77" height="19" src="/web/20130908165151im_/http://www.healio.com/~/media/Images/Education Lab/Provider Logos/VindicoLogo4web.gif" alt="Vindico Medical Education"/>.</p> <p><span style="text-decoration: underline;"><strong>Support Statement:</strong></span> This activity is supported by an educational grant from <img width="110" height="29" src="/web/20130908165151im_/http://www.healio.com/~/media/Images/Education Lab/Provider Logos/genentech_sm.gif" alt="genentech_sm.gif"/>.</p> <p><span style="text-decoration: underline;"><strong>Target Audience:</strong></span> The intended audience for the activities is cardiologists, endocrinologists, and other healthcare professionals involved in the treatment of type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD).</p> <p><span style="text-decoration: underline;"><strong>Learning Objectives:</strong></span> At the conclusion of this activity participants should be able to: </p> <ol> <li>Review cardiovascular and cardiometabolic risk factors that contribute toward microvascular and macrovascular complications in patients with type 2 diabetes. </li> <li>Compare the mechanisms of action, safety and efficacy of therapeutics that offer glycemic control and that may potentially reduce cardiovascular disease risk. </li> <li>Evaluate clinical and cardiovascular outcomes data on the treatment of patients with type 2 diabetes who have experienced or are at risk for acute coronary events, to enable physicians to choose optimal medical regimens that significantly reduce cardiovascular risk in their patients.</li> </ol> <p><span style="text-decoration: underline;"><strong>Course Chair: </strong></span><br/> <strong>R. Scott Wright, MD<br/> </strong>Professor of Medicine<br/> Mayo Clinic College of Medicine<br/> <em>Rochester, Minnesota </em></p> <p><span style="text-decoration: underline;"><strong>Faculty:</strong></span><br/> <strong>A. Michael Lincoff, MD </strong><br/> Director, C5Research (Cleveland Clinic Coordinating Center for Clinical Research) <br/> Vice Chairman, Department of Cardiovascular Medicine <br/> Professor of Medicine <br/> Cleveland Clinic <br/> <em>Cleveland, Ohio </em></p> <p><strong>Jorge Plutzky, MD</strong><br/> Director, The Vascular Disease Prevention Program<br/> Associate Professor<br/> Harvard Medical School<br/> <em>Boston, Massachusetts</em></p> <p><span style="text-decoration: underline;"><strong>External Reviewer:</strong></span><br/> David Davidson, MD</p> <p><span style="text-decoration: underline;"><strong>Medical Writer:</strong></span><br/> Steve Pridgeon</p> <p><span style="text-decoration: underline;"><strong>Accreditation:</strong></span><br/> Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.</p> <p><span style="text-decoration: underline;"><strong>Credit Designation:</strong></span><br/> Vindico Medical Education designates this print supplement for a maximum of 1.25 <em>AMA PRA Category 1 Credit(s)</em>™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.</p> <p>This enduring material is approved for 1 year from the date of original release, March 1, 2013 to March 31, 2014.</p> <p><span style="text-decoration: underline;"><strong>How To Participate in this Activity and Obtain CME Credit:</strong></span><br/> To participate in this CME activity, you must read the objectives and articles, complete the CME posttest, and fill in the evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 7 out of 10 of the posttest questions correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an <em>AMA PRA Category 1 Credit(s)</em>™ certificate.</p> <p><span style="text-decoration: underline;"><strong>Disclosures:</strong></span><br/> In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all CME providers are required to disclose to the activity audience the<strong> relevant financial relationships </strong>of the planners, teachers, and authors involved in the development of CME content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the last 12 months with a commercial interest whose products or services are discussed in the CME activity content over which the individual has control.</p> <p>The authors disclose that they do have significant financial interests in any products or class of products discussed directly or indirectly in this activity, including research support.</p> <p><span style="text-decoration: underline;">Planning Committee and Faculty members report the following relationship(s):</span><br/> <strong>A. Michael Lincoff, MD </strong><br/> <em>Contracted Research:</em> Lilly, Roche</p> <p><strong>Jorge Plutzky, MD </strong><br/> There is no direct duality of interest with this mechanistic review. Dr. Plutzky has served as a counsultant for pharmaceutical and biotechnology companies in regard to diabetes and obesity drugs, including Abbott, Amylin Pharmaceuticals, AstraZeneca, Bristol-Myers Squibb, Daiichi Sankyo, Ember, GlaxoSmithKline, Janssen, Merck, Novo Nordisk, Roche/Genentech, Orexigen, Pfizer, sanofi-aventis, Takeda, Vivus.</p> <p><strong>R. Scott Wright, MD</strong><br/> <em>Consulting Fees:</em> 3M, Genentech, Roche</p> <p><span style="text-decoration: underline;">External Reviewer reports the following relationship(s):</span><br/> <strong>David Davidson, MD</strong><br/> No relevant financial relationships to disclose.</p> <p><span style="text-decoration: underline;">Medical Writer reports the following relationship(s):</span><br/> <strong>Steve Pridgeon</strong><br/> No relevant financial relationships to disclose.</p> <p><span style="text-decoration: underline;">Vindico Medical Education staff report the following relationship(s):</span><br/> No relevant financial relationships to disclose.</p> <p>Signed disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.</p> <p><span style="text-decoration: underline;"><strong>Unlabeled and Investigational Usage:</strong></span><br/> The audience is advised that this continuing medical education activity may contain references to unlabeled uses of FDA-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non-FDA approved or investigational use of products/devices.</p> <p><span style="text-decoration: underline;"><strong>Copyright Statement:</strong></span><br/> Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2013 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. 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Above and Beyond Glycemic Control: Reducing the Risk of Cardiovascular Disease - CME Information | Endocrinology Education Lab