CINXE.COM

Cancer Related-Genes Enriched in Peripheral Blood Mononuclea | 99764

<!doctype html> <html lang="hi"> <head> <title>Cancer Related-Genes Enriched in Peripheral Blood Mononuclea | 99764</title> <meta name="keywords" content="Maryam Izad1*, Ehsan Ahmadi1, Mostafa Changaei1, Alireza Teymouri2, Behruz Alipour3, "/> <meta name="description" content="Background: Since COVID-19 has become one of the biggest challenges for health care systems in the past decade. The SARS-CoV-2 primarily affects the lungs,..99764"/> <meta name="citation_publisher" content="लॉन्गडम पब्लिशिंग एसएल" /> <meta name="citation_journal_title" content="ग्लोबल जर्नल ऑफ लाइफ साइंसेज एंड बायोलॉजिकल रिसर्च"> <meta name="citation_title" content="Cancer Related-Genes Enriched in Peripheral Blood Mononuclear Cells (PBMCs) of COVID-19 Patients: A Bioinformatics Study"> <meta name="citation_author" content="Maryam Izad1" /> <meta name="citation_author" content="Ehsan Ahmadi1" /> <meta name="citation_author" content="Mostafa Changaei1" /> <meta name="citation_author" content="Alireza Teymouri2" /> <meta name="citation_author" content="Behruz Alipour3" /> <meta name="citation_year" content=""> <meta name="citation_volume" content="9"> <meta name="citation_issue" content="1"> <meta name="citation_abstract" content="Background: Since COVID-19 has become one of the biggest challenges for health care systems in the past decade. The SARS-CoV-2 primarily affects the lungs, but many studies implied that other health complications such as brain damage, heart failure, and kidneys dysfunction also are associated with SARS-CoV-2 infection. Many scientific efforts have revealed the clinical and molecular details of SARS-CoV-2 pathogenesis. However, comprehension of COVID-19 complications demands more investigations. In this context, the relation between SARS-CoV-2 infection and cancer has been less addressed. In this regard, we aimed to discover any possible links between SARS-CoV-2 infection and cancer development in a bioinformatics study. Methods: The pertinent datasets were chosen from the GEO database. COVID-19 was searched for differentially expressed genes where |Log2 FC|&gt;1 and P&lt;0.05 were deemed statistically significant. The Cluster Profiler package employed gene ontology and pathway enrichment analysis for common genes. Functional interaction of proteins was predicted using STRING online, then Cytoscape analysis was carried out to determine the target genes. Finally, gene set enrichment analysis was performed to find any correlation between candidate genes and different types of cancer. Results: The analysis showed that numerous cancer-related genes up-regulated in SARS-CoV-2 infected patients, particularly those genes participating in the cell cycle regulation or engaged in cellular senescence processes. Conclusion: Our findings suggest that SARS-CoV-2 can be considered a potential risk factor for increasing the probability of developing cancer."> <meta name="citation_abstract_html_url" content="https://hindi.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html"> <meta name="format-detection" content="telephone=no"> <meta http-equiv="Content-Language" content="hi"> <meta name="google-site-verification" content="NomPTP94YozsgvD3NEFpNqUfY88e0TU0L64zNzZTpd0" /> <meta itemprop="name" content="longdom" /> <meta http-equiv="X-UA-Compatible" content="IE=edge"> <meta name="ROBOTS" content="INDEX,FOLLOW"> <meta name="googlebot" content="INDEX,FOLLOW"> <meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"> <link rel="canonical" href="https://hindi.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html"> <link rel="alternate" href="https://hindi.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html" hreflang="hi-IN" /> <!-- Bootstrap CSS --> <link rel="stylesheet" href="https://stackpath.bootstrapcdn.com/bootstrap/4.3.1/css/bootstrap.min.css"> <link href="/assets/css/longdom.css" rel="stylesheet"> <link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/animate.css/3.7.0/animate.min.css"> <!-- Fontawesome CSS --> <link rel="stylesheet" href="https://use.fontawesome.com/releases/v5.7.1/css/all.css"> <link rel="stylesheet" href="https://maxcdn.bootstrapcdn.com/font-awesome/4.3.0/css/font-awesome.min.css"> <!-- Google Fonts --> <link href="https://fonts.googleapis.com/css?family=Montserrat:100,100i,200,200i,300,300i,400,400i,500,500i,600,600i,700,700i,800,800i,900,900i|Open+Sans:300,300i,400,400i,600,600i,700,700i,800,800i|Raleway:100,100i,200,200i,300,300i,400,400i,500,500i,600,600i,700,700i,800,800i,900,900i" rel="stylesheet"> <link href="/assets/css/ionicons.min.css" rel="stylesheet"> <!--====================== Custom Scrollbar CSS ========================== --> <link rel="stylesheet" href="/assets/css/jquery.mCustomScrollbar.min.css"> <link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/bootstrap-select/1.13.2/css/bootstrap-select.min.css"> <!--============ Globa CSS ================ --> <link rel="stylesheet" href="/assets/css/global.css"> <!--============ Styles ================ --> <link rel="stylesheet" href="/assets/css/styles.css"> <link rel="stylesheet" type="text/css" href="/assets/css/author.css"> <link rel="icon" href="/assets/img/favicon.png" type="image/gif"> <link rel="stylesheet" href="/assets/css/coolautosuggest.css"> <!-- Google tag (gtag.js) --> <script async src="https://www.googletagmanager.com/gtag/js?id=G-GH5GSYYKJG"></script> <script async src="https://pagead2.googlesyndication.com/pagead/js/adsbygoogle.js?client=ca-pub-8046643215361735" crossorigin="anonymous"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-KXSQ7HLJSZ'); </script> </head> <body> <header> <!--=======top Navbar==========--> <nav class="navbar navbar-expand-lg navbar-light bg-white shadow-sm deva541"> <div class="container"> <a class="navbar-brand" href="https://hindi.longdom.org/" title="यहाँ क्लिक करें"> <img src="/assets/img/longdom-logo.svg" alt="Logo" height="25"> </a> <button class="navbar-toggler" type="button" data-toggle="collapse" data-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation"> <span class="navbar-toggler-icon"></span> </button> <div class="collapse navbar-collapse justify-content-end" id="navbar"> <div class="navbar-nav"> <a class="nav-item nav-link" href="https://hindi.longdom.org/" title="यहाँ क्लिक करें">घर</a> <a class="nav-item nav-link" href="https://hindi.longdom.org/open-access-journals-list.html" title="यहाँ क्लिक करें">पत्रिकाओं</a> <div class="nav-item dropdown"> <a class="nav-link dropdown-toggle" href="#" id="Guidelines" role="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false">दिशानिर्देश और नीतियां</a> <div class="dropdown-menu" aria-labelledby="यहाँ क्लिक करें"> <a class="dropdown-item" href="https://hindi.longdom.org/editorial-policies.html" title="यहाँ क्लिक करें">संपादकीय नीतियाँ</a> <a class="dropdown-item" href="https://hindi.longdom.org/instructions-to-authors.html" title="यहाँ क्लिक करें">लेखकों को निर्देश</a> <a class="dropdown-item" href="https://hindi.longdom.org/policies.html" title="यहाँ क्लिक करें">नीतियों</a> <a class="dropdown-item" href="https://hindi.longdom.org/publication-ethics.html" title="यहाँ क्लिक करें">प्रकाशन नैतिकता</a> <a class="dropdown-item" href="https://hindi.longdom.org/reviewers.html" title="यहाँ क्लिक करें">समीक्षक</a> <a class="dropdown-item" href="https://hindi.longdom.org/terms-conditions.html" title="यहाँ क्लिक करें">नियम और शर्तें</a> </div> </div> <a class="nav-item nav-link" href="https://hindi.longdom.org/advertising.html" title="यहाँ क्लिक करें">विज्ञापन देना</a> <a class="nav-item nav-link" href="https://hindi.longdom.org/conferences.html" title="यहाँ क्लिक करें">सम्मेलन</a> <a class="nav-item nav-link" href="https://hindi.longdom.org/contact-us.html" title="यहाँ क्लिक करें">संपर्क करें</a> <!---languages drop down----> <div class="nav-item dropdown multi_lang j_multi_lang"> <a class="nav-link dropdown-toggle" href="#" id="multi_lang" role="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false">Language</a> <div class="dropdown-menu" aria-labelledby=""> <a class="dropdown-item" href="https://www.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html" title="English"> <img src="https://www.longdom.org/admin/flags/usa.png">English </a> <a class="dropdown-item" href="https://spanish.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html" title="Spanish"> <img src="https://www.longdom.org/admin/flags/spain.png">Spanish </a> <a class="dropdown-item" href="https://chinese.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html" title="Chinese"> <img src="https://www.longdom.org/admin/flags/china.png">Chinese </a> <a class="dropdown-item" href="https://russian.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html" title="Russian"> <img src="https://www.longdom.org/admin/flags/russia.png">Russian </a> <a class="dropdown-item" href="https://german.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html" title="German"> <img src="https://www.longdom.org/admin/flags/germany.png">German </a> <a class="dropdown-item" href="https://french.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html" title="French"> <img src="https://www.longdom.org/admin/flags/france.png">French </a> <a class="dropdown-item" href="https://japanese.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html" title="Japanese"> <img src="https://www.longdom.org/admin/flags/japan.png">Japanese </a> <a class="dropdown-item" href="https://portuguese.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html" title="Portuguese"> <img src="https://www.longdom.org/admin/flags/portugal.png">Portuguese </a> <a class="dropdown-item" href="https://telugu.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html" title="Telugu"> <img src="https://www.longdom.org/admin/flags/india.png">Telugu </a> <a class="dropdown-item" href="https://tamil.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html" title="Tamil"> <img src="https://www.longdom.org/admin/flags/india.png">Tamil </a> </div> </div> <!---languages drop down----> </div> <!-- <div class="form-group mb-0 ml-3"> <form id="tfnewsearch" role="search" action="https://hindi.longdom.org/search-results.php"> <div class="input-group"> <input type="text" name="keyword" id="keyword" required class="form-control rounded-0" pattern=".{4,40}" placeholder="Search.." aria-label="Recipient's username" aria-describedby="basic-addon2" title="4 to 40 characters" /> <div class="input-group-append"> <button class="btn btn-warning rounded-0" type="submit"><i class="fas fa-search"></i></button> </div> </div> </form> </div> --> </div> </div> </nav> </header> <!--===============Journal header part====================--> <section class="bg-info py-1"> <div class="container"> <div class="row align-items-center justify-content-between"> <!--===============logosection/journal name====================--> <div class="col-12 col-sm-8"> <h1 class="text-left text-white border-light-blue-200-before font-size-7">ग्लोबल जर्नल ऑफ लाइफ साइंसेज एंड बायोलॉजिकल रिसर्च<br><small class="float-right font-size-5">खुला एक्सेस</small></h1> </div> <!--===============logo section end====================--> <div class="col-12 col-sm-2 d-none d-sm-block"> <p class="lead">आईएसएसएन: 2456-3102</p> <!--========WhatsApp Number============--> </div> </div> </div> </section> <!--===============Journal Navbar====================--> <nav id="sticky-navbar" class="navbar navbar-expand-lg navbar-dark bg-primary py-0"> <div class="container"> <button class="navbar-toggler" type="button" data-toggle="collapse" data-target="#jrnlNavbar" aria-controls="jrnlNavbar" aria-expanded="false" aria-label="Toggle navigation"> <span class="navbar-toggler-icon"></span> </button> <div class="collapse navbar-collapse justify-content-center" id="jrnlNavbar"> <div class="navbar-nav"> <a class="nav-item nav-link " href="https://hindi.longdom.org/global-journal-life-sciences-biological-research.html" title="यहाँ क्लिक करें">जर्नल होम</a> <a class="nav-link " href="https://hindi.longdom.org/global-journal-life-sciences-biological-research/aim-and-scope.html" title="यहाँ क्लिक करें">उद्देश्य और दायरा</a> <div class="nav-item dropdown"> <a class="nav-link dropdown-toggle " title="यहाँ क्लिक करें" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false" href="#">लेखकों के लिए निर्देश <i class="fas fa-caret-down"></i></a> <div class="dropdown-menu" aria-labelledby="EditorialPanel"> <a class="dropdown-item" href="https://hindi.longdom.org/global-journal-life-sciences-biological-research/instructionsforauthors.html" title="यहाँ क्लिक करें">लेखकों के लिए निर्देश</a> <a class="dropdown-item" href="https://hindi.longdom.org/global-journal-life-sciences-biological-research/ethical-malpractices.html" title="यहाँ क्लिक करें">प्रकाशन नैतिकता और कदाचार बयान</a> </div> </div> <a class="nav-link " href="https://hindi.longdom.org/global-journal-life-sciences-biological-research/submissions.html" title="यहाँ क्लिक करें">पांडुलिपि जमा करें</a> <a class="nav-link " href="https://hindi.longdom.org/global-journal-life-sciences-biological-research/archive.html" title="यहाँ क्लिक करें">पुरालेख</a> <a class="nav-link active" href="" title="यहाँ क्लिक करें">दिशा-निर्देश</a> <a class="nav-item nav-link " href="https://hindi.longdom.org/global-journal-life-sciences-biological-research/contact-us.html" title="यहाँ क्लिक करें">संपर्क</a> </div> </div> </div> </nav> <section class="py-4 content"> <div class="container"> <div class="row"> <aside class="col-12 col-sm-3 order-last order-sm-first"> <!--==========Share This Page==================--> <div class="card shadow-sm sidebar mb-3" style="margin-top:10px"> <h6 class="card-header">इस लेख का हिस्सा</h6> <div class="card-body"> <nav class="nav social-icons social-icons-sm"> <a class="nav-link bg-facebook white" href="https://www.facebook.com/sharer.php?u=https://hindi.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html" target="_blank" title="Share with Facebook" rel="noopener"><i class="fab fa-facebook-f"></i></a> <a class="nav-link bg-twitter white" href="https://twitter.com/share?url=https://hindi.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html" rel="noopener" target="_blank" title="Share with Twitter"><i class="fab fa-twitter"></i></a> <a class="nav-link bg-linkedin white" href="https://www.linkedin.com/shareArticle?mini=true&url=https://hindi.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html" rel="noopener" target="_blank" title="Share with Linkdin"><i class="fab fa-linkedin-in"></i></a> <a class="nav-link bg-googleplus white" href="https://plus.google.com/share?url=https://hindi.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html" target="_blank" rel="noopener" title="Share with Google+"><i class="fab fa-google-plus-g"></i></a> <a class="nav-link bg-pinterest white" href="https://pinterest.com/pin/create/button/?url=https://hindi.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html" rel="noopener" target="_blank" title="Share with Pintrest"><i class="fab fa-pinterest-p"></i></a> <a class="nav-link bg-blogger white" href="https://www.blogger.com/blog-this.g?u=https://hindi.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html" rel="noopener" target="_blank" title="Share with Blogger"><i class="fab fa-blogger-b"></i></a> </nav> </div> </div> <div class="card shadow-sm sidebar mb-3"> <h6 class="card-header pr-0">में अनुक्रमित</h6> <div class="list-group list-group-flush overflow-view"> <div class="list-group-item p-0 pt-2 pl-2"> <img src="https://www.longdom.org//admin/indexing-logos/euro-pub-123.png" alt="Logo" width="50%"> </div> <div class="list-group-item p-0 pt-2 pl-2"> <img src="https://www.longdom.org//admin/indexing-logos/google-scholar-124.jpg" alt="Logo" width="50%"> </div> </div> <p class="m-0 clearfix"><a href="https://hindi.longdom.org/global-journal-life-sciences-biological-research/indexing.html" title="यहाँ क्लिक करें"><span class="btn btn-warning btn-xs float-right">और देखें &raquo;</span></a></p> </div> <!--========== indexedin end==================--> <!--===========Useful Links=================--> <div class="card shadow-sm sidebar mb-3"> <h6 class="card-header">उपयोगी कड़ियां</h6> <div class="card-body p-0"> <nav class="nav flex-column font-size-3 icon-list icon-list-angle-right a-py-1"> <a class="nav-item nav-link" href="https://hindi.longdom.org/global-journal-life-sciences-biological-research/aim-and-scope.html" title="यहाँ क्लिक करें">उद्देश्य और दायरा</a> <a class="nav-item nav-link" href="https://hindi.longdom.org/global-journal-life-sciences-biological-research/peer-review-process.html" title="यहाँ क्लिक करें">समकक्ष समीक्षा प्रक्रिया</a> <a class="nav-item nav-link" href="https://hindi.longdom.org/global-journal-life-sciences-biological-research/indexing.html" title="यहाँ क्लिक करें">अनुक्रमणिका एवं संग्रहण</a> <a class="nav-item nav-link" href="https://hindi.longdom.org/global-journal-life-sciences-biological-research/archive.html" title="यहाँ क्लिक करें">अनुक्रमणिका एवं संग्रहण</a> <a class="nav-item nav-link" href="https://www.longdom.org/submissions/global-life-sciences-biological-research.html" title="यहाँ क्लिक करें">पांडुलिपि जमा करें</a> </nav> </div> </div> <!--==========relevant topics==================--> <!--Twitter starting--> <!--Twitter ending--> <!--===========open access journals=================--> <div class="card shadow-sm sidebar mb-3"> <h6 class="card-header">एक्सेस जर्नल खोलें</h6> <div class="card-body p-0 scroll_mang"> <nav class="nav flex-column font-size-3 icon-list icon-list-angle-right a-py-1"> <a class="nav-item nav-link" href="https://hindi.longdom.org/engineering-journals.html" title="यहाँ क्लिक करें">अभियांत्रिकी</a><br> <a class="nav-item nav-link" href="https://hindi.longdom.org/genetics-and-molecular-biology-journals.html" title="यहाँ क्लिक करें">आनुवंशिकी एवं आण्विक जीवविज्ञान</a><br> <a class="nav-item nav-link" href="https://hindi.longdom.org/immunology-and-microbiology-journals.html" title="यहाँ क्लिक करें">इम्यूनोलॉजी और माइक्रोबायोलॉजी</a><br> <a class="nav-item nav-link" href="https://hindi.longdom.org/pharmaceutical-sciences-journals.html" title="यहाँ क्लिक करें">औषधि विज्ञान</a><br> <a class="nav-item nav-link" href="https://hindi.longdom.org/agri-and-aquaculture-journals.html" title="यहाँ क्लिक करें">कृषि और जलकृषि</a><br> <a class="nav-item nav-link" href="https://hindi.longdom.org/medical-sciences-journals.html" title="यहाँ क्लिक करें">चिकित्सीय विज्ञान</a><br> <a class="nav-item nav-link" href="https://hindi.longdom.org/biochemistry-journals.html" title="यहाँ क्लिक करें">जीव रसायन</a><br> <a class="nav-item nav-link" href="https://hindi.longdom.org/bioinformatics-and-systems-biology-journals.html" title="यहाँ क्लिक करें">जैव सूचना विज्ञान और सिस्टम जीवविज्ञान</a><br> <a class="nav-item nav-link" href="https://hindi.longdom.org/neuroscience-and-psychology-journals.html" title="यहाँ क्लिक करें">तंत्रिका विज्ञान और मनोविज्ञान</a><br> <a class="nav-item nav-link" href="https://hindi.longdom.org/nursing-and-health-care-journals.html" title="यहाँ क्लिक करें">नर्सिंग एवं स्वास्थ्य देखभाल</a><br> <a class="nav-item nav-link" href="https://hindi.longdom.org/clinical-sciences-journals.html" title="यहाँ क्लिक करें">नैदानिक ​​विज्ञान</a><br> <a class="nav-item nav-link" href="https://hindi.longdom.org/food-and-nutrition-journals.html" title="यहाँ क्लिक करें">भोजन एवं पोषण</a><br> <a class="nav-item nav-link" href="https://hindi.longdom.org/chemistry-journals.html" title="यहाँ क्लिक करें">रसायन विज्ञान</a><br> <a class="nav-item nav-link" href="https://hindi.longdom.org/business-and-management-journals.html" title="यहाँ क्लिक करें">व्यवसाय प्रबंधन</a><br> <a class="nav-item nav-link" href="https://hindi.longdom.org/general-science-journals.html" title="यहाँ क्लिक करें">सामान्य विज्ञान</a><br> </nav> </div> </div> <!--===========open access journals=================--> </aside> <div class="col-12 col-sm-9"> <h2 class="heading-1">अमूर्त</h2> <h3 class="">Cancer Related-Genes Enriched in Peripheral Blood Mononuclear Cells (PBMCs) of COVID-19 Patients: A Bioinformatics Study</h3> <p> <i class="fas fa-user"></i> Maryam Izad1*, Ehsan Ahmadi1, Mostafa Changaei1, Alireza Teymouri2, Behruz Alipour3 </p> <p><strong>Background: </strong>Since COVID-19 has become one of the biggest challenges for health care systems in the past decade. The SARS-CoV-2 primarily affects the lungs, but many studies implied that other health complications such as brain damage, heart failure, and kidneys dysfunction also are associated with SARS-CoV-2 infection. Many scientific efforts have revealed the clinical and molecular details of SARS-CoV-2 pathogenesis. However, comprehension of COVID-19 complications demands more investigations. In this context, the relation between SARS-CoV-2 infection and cancer has been less addressed. In this regard, we aimed to discover any possible links between SARS-CoV-2 infection and cancer development in a bioinformatics study.</p> <p><strong>Methods:</strong> The pertinent datasets were chosen from the GEO database. COVID-19 was searched for differentially expressed genes where |Log2 FC|&gt;1 and P&lt;0.05 were deemed statistically significant. The Cluster Profiler package employed gene ontology and pathway enrichment analysis for common genes. Functional interaction of proteins was predicted using STRING online, then Cytoscape analysis was carried out to determine the target genes. Finally, gene set enrichment analysis was performed to find any correlation between candidate genes and different types of cancer.</p> <p><strong>Results</strong>: The analysis showed that numerous cancer-related genes up-regulated in SARS-CoV-2 infected patients, particularly those genes participating in the cell cycle regulation or engaged in cellular senescence processes.</p> <p><strong>Conclusion:</strong> Our findings suggest that SARS-CoV-2 can be considered a potential risk factor for increasing the probability of developing cancer.</p> <div class="alert alert-info text-left"><b>अस्वीकरण:</b> इस सार का अनुवाद कृत्रिम बुद्धिमत्ता उपकरणों का उपयोग करके किया गया था और अभी तक इसकी समीक्षा या सत्यापन नहीं किया गया है।</div> <div class="nav social-icons"> <a class="nav-link w-auto">इस लेख का हिस्सा</a> <a title="यहाँ क्लिक करें" target="_blank" href="https://www.facebook.com/sharer.php?u=https://hindi.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html" rel="noopener"><i class="fab fa-facebook-f"></i></a> <a class="nav-link" title="यहाँ क्लिक करें" target="_blank" href="https://twitter.com/share?url=https://hindi.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html" rel="noopener"><i class="fab fa-twitter"></i></a> <a class="nav-link" title="यहाँ क्लिक करें" target="_blank" href="https://www.linkedin.com/shareArticle?mini=true&url=https://hindi.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html" rel="noopener"><i class="fab fa-linkedin-in"></i></a> <a class="nav-link" title="यहाँ क्लिक करें" target="_blank" href="https://plus.google.com/share?url=https://hindi.longdom.org/abstract/cancer-relatedgenes-enriched-in-peripheral-blood-mononuclear-cells-pbmcs-of-covid19-patients-a-bioinformatics-study-99764.html" rel="noopener"><i class="fab fa-google-plus-g"></i></a> </div> </div> </div> </div> </section> <footer class="bg-blue-grey-900 py-3"> <div class="container"> <div class="row"> <div class="col-12 col-sm-4"> <h4 class="white font-size-4 fweight-400 border-bottom-1 pb-2">सामग्री लिंक</h4> <ul class="list-unstyled footer-links font-size-3"> <li><a class="" href="https://hindi.longdom.org/privacy-policy.html" title="यहाँ क्लिक करें">गोपनीयता नीति</a></li> <li><a class="" href="https://hindi.longdom.org/terms-conditions.html" title="यहाँ क्लिक करें">नियम एवं शर्तें</a></li> <li><a class="" href="https://hindi.longdom.org/authors-reviewers-editors.html" title="यहाँ क्लिक करें">लेखक, समीक्षक और संपादक</a></li> </ul> </div> <div class="col-12 col-sm-4"> <h4 class="white font-size-4 fweight-400 border-bottom-1 pb-2">लॉन्गडोम से संपर्क करें</h4> <p><strong>लॉन्गडम ग्रुप एसए</strong><br /> एवेन्यू रोजर वांडेन्ड्रिस्शे,<br /> 18, 1150 ब्रुसेल्स, बेल्जियम<br /> फ़ोन: +442038085340<br/> <strong>ईमेल:</strong> <a class='white' href='mailto:info@longdom.org' title='यहां क्लिक करें'>info@longdom.org</a></p> </div> <div class="col-12 col-sm-4"> <h4 class="white font-size-4 fweight-400 border-bottom-1 pb-2">जोड़ना</h4> <nav class="nav nav-pills social-icons-footer flex-column a-pl-0"> <a href="https://www.facebook.com/longdompublisher" title="यहाँ क्लिक करें" target="_blank" class="nav-link bg-facebook-hover"><i class="fab fa-facebook-f bg-facebook"></i></a> <a href="https://www.linkedin.com/company/longdom-publishing-sl/" title="यहाँ क्लिक करें" target="_blank" class="nav-link bg-linkedin-hover"><i class="fab fa-linkedin-in bg-linkedin"></i></a> <a href="https://twitter.com/LongdomP" title="यहाँ क्लिक करें" target="_blank" class="nav-link bg-twitter-hover"><i class="fab fa-twitter bg-twitter"></i></a> <a href="https://www.instagram.com/longdom_publisher/" title="यहाँ क्लिक करें" target="_blank" class="nav-link bg-instagram-hover"><i class="fab fa-instagram bg-instagram"></i></a> </nav> </div> </div> <div class="row text-center"> <div class="col"> <p>कॉपीराइट &copy; 2024 <a href="https://hindi.longdom.org/" title="यहाँ क्लिक करें" class="white">लॉन्गडम पब्लिशिंग एसएल</a>.</p> </div> </div> </div> </footer> <!--========================== Scroll To Top ============================--> <a href="#0" class="cd-top js-cd-top">Top</a> <!-- Optional JavaScript --> <!-- jQuery first, then Popper.js, then Bootstrap JS --> <script src="https://code.jquery.com/jquery-3.3.1.min.js"></script> <script src="https://cdnjs.cloudflare.com/ajax/libs/popper.js/1.14.7/umd/popper.min.js"></script> <script src="https://stackpath.bootstrapcdn.com/bootstrap/4.3.1/js/bootstrap.min.js"></script> <!--Get the app icon js--> <script> jQuery(function($) { $(window).scroll(function fix_element() { $('#target').css( $(window).scrollTop() > 100 ? { 'position': 'fixed', 'top': '440px' } : { 'position': 'absolute', 'top': '440px' } ); return fix_element; }()); }); </script> <!--Get the app icon js end--> <!--========================== Feather Icons ============================--> <script src="https://unpkg.com/feather-icons"></script> <script> feather.replace() </script> <!--========================== Scroll To Top ============================--> <script src="/assets/js/scroll-to-top.js"></script> <!--========================== mCustomScrollbar ============================--> <script type="text/javascript" src="/assets/js/coolautosuggest.js"></script> <script language="javascript" type="text/javascript"> $("#keyword").coolautosuggest({ url: "https://hindi.longdom.org/author-names.php?chars=", minChars: 3, }); </script> <script src="/assets/js/jquery.mCustomScrollbar.concat.min.js"></script> <script> // Scrollbar var Scrollbar = function() { "use strict"; // Handle Scrollbar Linear var handleScrollbarLinear = function() { $(".scrollbar").mCustomScrollbar({ theme: "minimal-dark" }); } return { init: function() { handleScrollbarLinear(); // initial setup for scrollbar linear } } }(); $(document).ready(function() { Scrollbar.init(); }); /*========================== Stikcy Navbar ============================*/ window.onscroll = function() { myFunction() }; var navbar = document.getElementById("sticky-navbar"); var sticky = navbar.offsetTop; function myFunction() { if (window.pageYOffset >= sticky) { navbar.classList.add("sticky") } else { navbar.classList.remove("sticky"); } } /*========================== Bootstrap Popover ============================*/ $(function () { $('[data-toggle="popover"]').popover() }) </script> <!--========================== Page Scroll to ID ============================--> <script src="/assets/js/jquery.malihu.PageScroll2id.min.js"></script> <script> (function($){ $(window).on("load",function(){ $("a[rel='m_PageScroll2id']").mPageScroll2id(); }); })(jQuery); </script> <!--========================== Equal Height ============================--> <script type="text/javascript" src="/assets/js/jquery.matchHeight-min.js"></script> <script> $(function() { $('.match-height').matchHeight({ byRow: true, property: 'height', target: null, }); }); </script> <script type="text/javascript" src="/assets/js/grids.min.js"></script> <script type="text/javascript"> // Equal Height var EqualHeight = function() { "use strict"; // Handle Equal Height var handleEqualHeight = function() { $(function($) { $('.equal-height').responsiveEqualHeightGrid(); }); } return { init: function() { handleEqualHeight(); // initial setup for equal height } } }(); $(document).ready(function() { EqualHeight.init(); }); </script> <!--================ Select Picker ==================--> <script src="https://cdnjs.cloudflare.com/ajax/libs/bootstrap-select/1.13.2/js/bootstrap-select.min.js"></script> <script> $('.selectpicker').selectpicker(); </script> <script> $(document).ready(function(){ var filecount = 1; $('.filerowclass').each(function(){ var countattr = $(this).attr('countattr'); if(filecount == countattr){ var countlink = $('#rowfile'+countattr+ ' .filelinkclass').length; if(countlink == 0){ $('#rowfile'+countattr).remove(); } } filecount++; }); }); </script> <link href="https://cdn.jsdelivr.net/npm/select2@4.1.0-rc.0/dist/css/select2.min.css" rel="stylesheet" /> <script src="https://cdn.jsdelivr.net/npm/select2@4.1.0-rc.0/dist/js/select2.min.js"></script> </body> </html>

Pages: 1 2 3 4 5 6 7 8 9 10