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</div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">Från Wikipedia</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="sv" dir="ltr"><figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/Fil:SalmonellaNIAID.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b4/SalmonellaNIAID.jpg/250px-SalmonellaNIAID.jpg" decoding="async" width="250" height="210" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b4/SalmonellaNIAID.jpg/375px-SalmonellaNIAID.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b4/SalmonellaNIAID.jpg/500px-SalmonellaNIAID.jpg 2x" data-file-width="2100" data-file-height="1761" /></a><figcaption>Salmonella angriper en odlad cell</figcaption></figure> <p><b>Cellulär mikrobiologi</b> är en kombination av både <a href="/wiki/Mikrobiologi" title="Mikrobiologi">mikrobiologi</a> och <a href="/wiki/Cellbiologi" title="Cellbiologi">cellbiologi</a>. Det handlar om att få processen i infektioner på cellnivå dvs om hur patogener manipulera cellulära processer. Fenomenet <i>cell mikrobiologi</i> nämns 1996 i en vetenskapsartikel. <sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-reference-link-bracket">[</span>1<span class="cite-reference-link-bracket">]</span></a></sup><sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-reference-link-bracket">[</span>2<span class="cite-reference-link-bracket">]</span></a></sup> </p><p>Cellulär mikrobiologi försöker använda <a href="/wiki/Patogena" class="mw-redirect" title="Patogena">patogena</a> <a href="/wiki/Mikrob" class="mw-redirect" title="Mikrob">mikrober</a> (smittämnen) som verktyg för cellbiologisk forskning och för att skapa cellbiologiska metoder för att kunna förstå patogeniteten av mikrober. Man har använt gifter och virulensfaktorer från olika mikrober i årtionden för att påverka processer i <a href="/wiki/Eukaryoter" title="Eukaryoter">eukaryota</a> celler. Många eukaryota cellulära processer har förtydligats med hjälp av mikrobiella "verktyg" . Ett stort ämne i denna kategori är <a href="/wiki/Cytoskelett" class="mw-redirect" title="Cytoskelett">cytoskelettet</a>. Många mikrober modifieras och påverkar synten/nedbrytningen av värdcellscytoskelettet, speciellt <a href="/wiki/Aktin" title="Aktin">aktinnätverket</a>. Bakterier som <a href="/wiki/Salmonella" title="Salmonella">salmonella</a> och <a href="/wiki/Shigella" title="Shigella">shigella</a>, framkallar aktin-polymerisation i värdceller som annars inte skulle gå i gång i mikrober. Detta ger upphov till en bildning av en ny uppbyggnad celler men som till sist blir uppslukade av bakterierna. Bakterier som <a href="/wiki/Yersinia" title="Yersinia">Yersinia</a> hämmar aktin-polymerisation i <a href="/wiki/Fagocyt" title="Fagocyt">fagocyter</a> och därmed förhindrar spridningen. </p><p>Cellular mikrobiologi försöker att förstå dessa processer och hur de främjar infektioner. I cellulär mikrobiologi använder man sig av mikroorganiser för att senare skapa och modifiera immunförsvaret för att se hur olika <a href="/wiki/Virus" title="Virus">virus</a> påverkar. <sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-reference-link-bracket">[</span>3<span class="cite-reference-link-bracket">]</span></a></sup> </p><p>Nyligen har cellulär mikrobiologi införts för att undersöka cellbiologi av mikrober själva. <sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-reference-link-bracket">[</span>4<span class="cite-reference-link-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Noter">Noter</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Cellul%C3%A4r_mikrobiologi&veaction=edit&section=1" title="Redigera avsnitt: Noter" class="mw-editsection-visualeditor"><span>redigera</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Cellul%C3%A4r_mikrobiologi&action=edit&section=1" title="Redigera avsnitts källkod: Noter"><span>redigera wikitext</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-1"><a href="#cite_ref-1">^</a> <span class="reference-text">Matthew R. Hendricks , Jennifer M. Bomberger 1 februari 2013 <a rel="nofollow" class="external free" href="http://ajpcell.physiology.org/content/306/3/C187.full">http://ajpcell.physiology.org/content/306/3/C187.full</a> .</span> </li> <li id="cite_note-2"><a href="#cite_ref-2">^</a> <span class="reference-text">Manash Universy, 15 augusti 2013 <cite style="font-style:normal" class="web"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20140527214216/http://med.monash.edu/biochem/nhmrc/">”Arkiverade kopian”</a>. Arkiverad från <a rel="nofollow" class="external text" href="http://med.monash.edu/biochem/nhmrc/">originalet</a> den 27 maj 2014<span class="printonly">. <a rel="nofollow" class="external free" href="https://web.archive.org/web/20140527214216/http://med.monash.edu/biochem/nhmrc/">https://web.archive.org/web/20140527214216/http://med.monash.edu/biochem/nhmrc/</a></span><span class="reference-accessdate">. Läst 26 maj 2014</span>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.btitle=Arkiverade+kopian&rft.atitle=&rft_id=https%3A%2F%2Fweb.archive.org%2Fweb%2F20140527214216%2Fhttp%3A%2F%2Fmed.monash.edu%2Fbiochem%2Fnhmrc%2F&rfr_id=info:sid/en.wikipedia.org:Cellul%C3%A4r_mikrobiologi"><span style="display: none;"> </span></span>.</span> </li> <li id="cite_note-3"><a href="#cite_ref-3">^</a> <span class="reference-text">Researchgate 2014 <a rel="nofollow" class="external free" href="http://www.researchgate.net/journal/1462-5822_Cellular_Microbiology">http://www.researchgate.net/journal/1462-5822_Cellular_Microbiology</a>.</span> </li> <li id="cite_note-4"><a href="#cite_ref-4">^</a> <span class="reference-text">Matthew R. Hendricks , Jennifer M. Bomberger 1 februari 2014 <a rel="nofollow" class="external free" href="http://ajpcell.physiology.org/content/306/3/C187.full">http://ajpcell.physiology.org/content/306/3/C187.full</a> .</span> </li> </ol></div> <style data-mw-deduplicate="TemplateStyles:r56287950">.mw-parser-output table.navbox{border:#aaa 1px solid;width:100%;margin:auto;margin-top:1em;clear:both;font-size:88%;text-align:center;padding:1px}.mw-parser-output link+table.navbox{margin-top:-1px}.mw-parser-output .navbox-title,.mw-parser-output .navbox-abovebelow,.mw-parser-output table.navbox th{text-align:center;padding-left:1em;padding-right:1em}.mw-parser-output .navbox-thlinkcolor .navbox-title button,.mw-parser-output .navbox-thlinkcolor .navbox-title .mw-collapsible-text,.mw-parser-output .navbox-thlinkcolor .navbox-title a{color:inherit}.mw-parser-output .nowraplinks a,.mw-parser-output .nowraplinks .selflink{white-space:nowrap}.mw-parser-output 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