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Godwin Laboratory

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Dr. Godwin&#39;s studies primarily involve four different types of cancer: breast, ovarian, Ewing sarcoma and gastrointestinal stromal tumor (GIST)." /> <meta property="og:image" content="https://www.kumc.edu/images/_shared/social%20media/social-og-image.jpg" /> <meta name="twitter:image:src" content="https://www.kumc.edu/images/_shared/social%20media/social-og-image.jpg" /> <meta name="twitter:card" content="summary_large_image" /> <meta name="twitter:title" content="Godwin Laboratory" /> <meta name="twitter:description" content="Godwin and members of his group have been involved in both basic and translational research for many years. 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class="container"> <div class="row"> <div class="col-12"> <div class="parent-section-link"> <a href="/school-of-medicine/academics/departments/pathology/research/view-all-labs.html"><i class="fas fa-arrow-left"></i> View All Labs</a> </div> </div> </div> </div> <div class="container"> <div class="row"> <div class="col-12"> <div class="container"> <h1 >Godwin Laboratory</h1></div> <div class="text-intro"> </div> </div> </div> <div class="row"> <div class="col-12 col-lg-8 order-2 order-lg-1"> <div class="content-copy" ><p><img alt="Portrait of Cassie Shipman" class="img-fluid mb-4" height="125" width="95" title="Cassie Shipman - images/pathology/shipman_cassie.jpg" src="../../../../../../images/pathology/shipman_cassie.jpg" /></p> <h3><img class="float-md-left mr-0 mr-md-3 mb-4 d-block img-fluid" src="../../../../../../images/Pathology/andrew-godwin-lab.jpg" alt="Andrew Godwin portrait" title="images/Pathology/andrew-godwin-lab.jpg" width="239" height="334" /> Andrew K. Godwin, PhD</h3> <p><strong>Endowed Professor</strong><br /><strong>Division Director, Genomic Diagnostics and Founding Director of Molecular Oncology, Department of Pathology &amp; Laboratory Medicine</strong><br /><strong>Deputy Director of the KU Cancer Center</strong><br /><strong>Founding Director of the Kansas Institute for Precision Medicine</strong></p> <p>Andrew K. Godwin, PhD, is the Chancellor's Distinguished Chair in Biomedical Sciences, an endowed Professor, and the Division Director of Genomic Diagnostics in the Department of Pathology at KUMC. He also leads our institutional efforts in precision medicine. In 2019, he was awarded an $11.5 million Centers of Biomedical Research Excellence (COBRE) grant from the NIH/NIGMS to develop the Kansas Institute for Precision Medicine (KIPM) at KUMC.</p> <p>Dr. Godwin was recruited to KUMC as the Associate Director for Translational Research for the KU Cancer Center in October 2010 after 26 productive years at Fox Chase Cancer Center in Philadelphia, PA. His engaged participation contributed to NCI designation in 2012, and he was named the Deputy Director in 2013. He serves as a professor of Pathology and Laboratory Medicine and the founding director of the Clinical Molecular Oncology Laboratory, a CLIA-certified, CAP-accredited molecular diagnostics laboratory for the KU Health System. Dr. Godwin also serves as the founding Director of both the KU Cancer Center&rsquo;s Biospecimen Shared Resource and the KU Medical Center&rsquo;s Biospecimen Repository Core Facility, as well as the founding Scientific Director for the Biomarker Discovery Laboratory (BDL), which supports integral and integrated biomarker studies for clinical trials.</p> <p>Dr. Godwin holds secondary appointments as a Professor in the Department of Cancer Biology, the Department of Internal Medicine, and the Department of Microbiology, Molecular Genetics, and Immunology at KUMC. He is also an adjunct Professor for the Bioengineering Program at the University of Kansas. He was named a Kansas Bioscience Authority Eminent Scholar in 2010 and the University of Kansas School of Medicine Chancellor&rsquo;s Distinguished Chair in Biomedical Sciences Endowed Professor in 2012. In 2014, Dr. Godwin received the KUMC School of Medicine&rsquo;s Achievement Award for mentoring post-doctorate students. Of his awards, he is most proud of being acknowledged for his years of mentoring.</p> <p>Dr. Godwin has mentored over 120 trainees, including high school students, undergraduates, graduate students, postdoctoral associates/fellows, medical students/fellows, visiting scientists, and junior faculty during his academic career. He was awarded the KU Medical Center&rsquo;s Faculty Investigator Research Award in 2015, the University of Kansas Cancer Center Director&rsquo;s William Jewell Team Science Award in 2017, the KUCC Director&rsquo;s Basic Science Award in 2018, the Chancellor&rsquo;s Club Award in 2018, the Higuchi-KU Endowment Research Achievement Award in Biomedical Sciences in 2020&mdash;the state higher education system&rsquo;s most prestigious recognition for scholarly excellence&mdash;and most recently the 2021 KU School of Medicine Excellence in Mentoring (Faculty) award.</p> <p>Dr. Godwin is a leader in the field of translational research and precision medicine. His laboratories at KUMC continue to focus on various aspects of both basic and translational research, with an emphasis on early detection of cancer, predictive and prognostic biomarkers, liquid biopsies based on extracellular vesicles, molecular therapeutics, companion diagnostics, clinical trials, cellular therapeutics, cancer immune microenvironment, and biosample ascertainment. He is a NIH/NCI/NIGMS-funded investigator (continuously since his first faculty appointment at Fox Chase Cancer Center in 1993) and a highly published (over 500 manuscripts and scholarly review articles) and cited (over 65,000; h-index of 130) scientist. Dr. Godwin is internationally recognized for his molecular biology/genetic studies of sarcoma (e.g., GIST and Ewing Sarcoma), breast and ovarian cancer, and his efforts to help bridge the gap between basic and clinical science to improve patient care. Dr. Godwin co-leads the ovarian cancer program at KUCC and has been the Translational Science Co-chair for many Gynecologic Oncology Group (GOG, now a part of the NRG) clinical trials evaluating molecularly targeted agents in recurrent ovarian and endometrial cancer patients. He is a member of the Early Therapeutics and Rare Cancers Committee and is the Vice Chair of the Breast Translational Medicine Subcommittee of the Southwest Oncology Group (since 2019). Dr. Godwin was appointed to the National Cancer Institute&rsquo;s NCTN Core Correlative Sciences Committee (NCTN-CCSC) in 2021. He led the first studies demonstrating that KRAS mutations were predictive of response to EGFR-targeted therapies (in collaboration with Bristol Myers Squibb) and was involved in the validation studies for the first and only clinically validated, FDA-cleared test for capturing and enumerating CTCs (CELLSEARCH&reg;) in collaboration with scientists at Immunicon (now Menarini Silicon Biosystems) to help inform clinical decision-making. His recent studies have focused on developing liquid-based biopsies to detect, diagnose, and track disease burden.</p> <p>Dr. Godwin has been a member of multiple disease-working groups for The Cancer Genome Atlas (TCGA), is a tissue source site for the Clinical Proteomic Tumor Analysis Consortium (CPTAC), is a member of the Early Detection Research Network (EDRN), the Breast Cancer Association Consortium (BCAC), and the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA). Dr. Godwin serves on the Early Therapeutics and Rare Cancers Committee and was named the Vice Chair for the Breast Translational Medicine Subcommittee of the Southwest Oncology Group in 2018. He has served on numerous grant peer-review panels, including those for the American Cancer Society, the National Institutes of Health, the U.S. Army Medical Research and Materiel Command, and the Mary Kay and Susan G. Komen Foundations. Dr. Godwin is active in ovarian cancer advocacy and has served on the board of directors for various cancer foundations. He has demonstrated a consistently high level of funding throughout his career from Federal, State, and private sources. He has been part of over 200 successful grant awards, totaling hundreds of millions of dollars in funding.</p> <p><a href="https://scholar.google.com/citations?user=1yBbt3MAAAAJ&amp;hl=en&amp;authuser=1" target="_blank" rel="noopener">View a complete list of Dr. Godwin's publications</a></p> <p>Ongoing efforts in Godwin's Research Program include scientists at all levels of experience.</p></div> </div> <div class="col-12 col-lg-3 offset-0 offset-lg-1 order-1 order-lg-2"> <aside role="complementary"> <div class="accordion" id="accordion-parent"> <div class="header d-none d-lg-block" > Godwin Lab Home </div> <div class="card"> <div class="card-header d-block d-lg-none" id="heading-1"> <button class="btn btn-link" type="button" data-toggle="collapse" data-target="#collapse-topical" aria-expanded="true" aria-controls="collapse-topical" > Godwin Lab Home <span> <span class="v"></span> <span class="h"></span> </span> </button> </div> <div id="collapse-topical" class="collapse show" aria-labelledby="heading-1" data-parent="#accordion-parent"> <div class="card-body"> <nav aria-label="In This Section Navigation" role="navigation"> <ul> <li> <a href="/school-of-medicine/academics/departments/pathology/research/view-all-labs/godwin-laboratory/lab-members.html" class=""><i class="fas fa-chevron-right"></i> Lab Members</a> </li> <li> <a href="/school-of-medicine/academics/departments/pathology/research/view-all-labs/godwin-laboratory/positions-available.html" class=""><i class="fas fa-chevron-right"></i> Positions Available</a> </li> <li> <a href="/school-of-medicine/academics/departments/pathology/research/view-all-labs/godwin-laboratory/news.html" class=""><i class="fas fa-chevron-right"></i> News</a> </li> </ul> </nav> </div> </div> </div> </div> </aside> </div> </div> </div> <div > <div > </div> <div > <div class="tray _call-out-tray _call-out-tray--blue tray--flush-top" > <div class="container"> <div class="row"> <div class="col-12"> <div class="call-out-content"> <h2 > Contact Us </h2> <div class="content-copy" ><div style="display: flex; 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