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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="blood uric acid level"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 17314</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: blood uric acid level</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17314</span> Association of Serum Uric Acid Level and Bone Mineral Density of Menopausal Women</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Soyeon%20Kang">Soyeon Kang</a>, <a href="https://publications.waset.org/abstracts/search?q=Youn-Jee%20Chung"> Youn-Jee Chung</a>, <a href="https://publications.waset.org/abstracts/search?q=Jung%20Namkung"> Jung Namkung</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: This retrospective study investigated the association between uric acid level and bone mineral density (BMD) in the postmenopausal period. Methods: The study included 328 menopausal women (mean age, 57.3 ± 6.5 years; mean serum uric acid level, 4.6 ± 1.0 mg/dL). Patients were divided into three groups by tertile of serum uric acid level. Patients who used hormone treatment (HT), bisphosphonates, or lipid-lowering agents were included. Results: Blood urea nitrogen, serum creatinine, and serum triglyceride levels were significantly higher in the upper uric acid tertiles. No significant difference was found in the mean uric acid levels between medication users and non-users. Distinct HT regimens showed different mean serum uric acid levels. In a cross-sectional analysis, higher serum uric acid levels showed a tendency toward increased BMD in the spine and femoral neck. Longitudinal analysis of 186 women who underwent follow-up examination at a mean interval of 14.6 months revealed a trend toward a smaller reduction in femoral neck BMD in women in the upper serum uric acid tertiles. Conclusion: A positive correlation exists between serum uric acid levels and BMD in menopausal women. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=menopause" title="menopause">menopause</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidant" title=" antioxidant"> antioxidant</a>, <a href="https://publications.waset.org/abstracts/search?q=uric%20acid" title=" uric acid"> uric acid</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20mineral%20density" title=" bone mineral density"> bone mineral density</a> </p> <a href="https://publications.waset.org/abstracts/115923/association-of-serum-uric-acid-level-and-bone-mineral-density-of-menopausal-women" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/115923.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">129</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17313</span> Effect of Organochlorine Insecticide (Endosulfan) on Albino Rat at the Rate of Blood Uric Acid Level</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bindu%20Kumari">Bindu Kumari</a>, <a href="https://publications.waset.org/abstracts/search?q=Bindu%20Kumari%20Singh"> Bindu Kumari Singh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Endosulfan is known to be one of the highly toxic agricultural pesticides commonly used in our societies. With the widespread use of Endosulfan in agriculture, human beings are most likely to be exposed to it, either orally by eating Endosulfan-contaminated foods or by nose and whole body inhalation in the farms during its application. The present study was conducted to observe the changes in the serum uric acid level of the Swiss albino rats due to the administration of Endosulfan. 3.0 mg Endosulfan/kg body weight was daily administered orally to albino rats for 28 days period. Alterations in their K.F.T. parameters were recorded at a regular interval of 7 days within this 28 days period and were compared with those of control rats. All rats were monitored for any observable toxic symptoms throughout the experimental period and they also were weighted weekly to monitor body weight gain. Alteration recorded in K.F.T. parameters within the groups were due to Endosulfan exposure and serum uric acid level was significantly elevated in the 3mg/kg dose group. Pathological changes of rats treated with Endosulfan were observed with typical signs of toxicity. Uric acid is a heterocyclic compound formed as an end product of metabolism of purine nucleotides. It forms ions and salts known as urate and acid urate which are harmful to our health. Uric acid clearance is one of the numerous important functions of the kidney. Defects in this process resulted in Gout, kidney stone or Kidney failure. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=KFT%20parameters" title="KFT parameters">KFT parameters</a>, <a href="https://publications.waset.org/abstracts/search?q=blood%20uric%20acid%20level" title=" blood uric acid level"> blood uric acid level</a>, <a href="https://publications.waset.org/abstracts/search?q=endosulfan" title=" endosulfan"> endosulfan</a>, <a href="https://publications.waset.org/abstracts/search?q=eat" title=" eat"> eat</a> </p> <a href="https://publications.waset.org/abstracts/29538/effect-of-organochlorine-insecticide-endosulfan-on-albino-rat-at-the-rate-of-blood-uric-acid-level" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/29538.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">291</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17312</span> The Effect of Aerobic Exercises on the Amount of Urea, Uric Acid and Creatine in Blood of Iranian Soccer Players</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Abdolrasoul%20Daneshjoo">Abdolrasoul Daneshjoo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The purpose of this research was to study the effect of aerobic exercises with 75% heart beats on the amount of urea, uric acid and creatine in blood of Iranian soccer national U-23 players. 27 players were selected according to the following demographic specifications: age: 21.4±1.60 years old; weight: 68±9.4 kg; height: 174.2±8.6 cm. Urea, uric acid and creatine in blood are considered as dependent variations where as 40 minutes running on a track with maximum 75% heart beats are independent variations. Heart beat and blood pressure in rest time, age, height, and weight are considered as the controlled variations. Maximum heart beats are recorded under maximum exercises (8 minutes and 150-250 watt energy) on ergo meter. Then, in order to determine independent variations, 75% maximum heart beats are considered for each player. Blood is taken twice (before and after determining independence variation). Moreover, the players are given a few instructions to be fulfilled 24 hours before the main exercises. Laboratory analysis method for blood urea sample is deacetyl ammoniom, for uric acid Karvy test and for creatine pyric acid. 'T' formula is applied for analyzing statistical data in dependent groups with degree of freedom 7 (d.f=7) urea and uric acid contain P>0.01 and P>0.05 for creatine. 1. Aerobic exercise can effect on the concentration of urea of blood as well as uric acid and creatine in blood serum and increase the amount of them. 2. Urea of blood serum increases from 26.75±2.59 to 28.9±2.67 (25%) with 40 minutes running and 75% heart beat. 3. Aerobic exercise causes uric acid increase 12.5% from 5.7±0.52 (before exercise) to 6.1±0.71 (after exercise). Creatine of blood serum increases from 1.36±0.27 (before exercise) to 1.85±0.49 (after exercise). We came to this result that during aerobic exercise catabolism of protein substrate increases. Moreover, augmentation of urea, uric acid and creatine in blood serum as metabolic poisons causes disorder in kidney. Also, tendons and joints are affected by these poisons. Appropriate diet and exercise can prevent production of these poisons resulted from heavy exercise. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=aerobic%20exercise" title="aerobic exercise">aerobic exercise</a>, <a href="https://publications.waset.org/abstracts/search?q=urea" title=" urea"> urea</a>, <a href="https://publications.waset.org/abstracts/search?q=uric%20acid" title=" uric acid"> uric acid</a>, <a href="https://publications.waset.org/abstracts/search?q=creatine" title=" creatine"> creatine</a>, <a href="https://publications.waset.org/abstracts/search?q=blood" title=" blood"> blood</a>, <a href="https://publications.waset.org/abstracts/search?q=soccer%20national%20players" title=" soccer national players "> soccer national players </a> </p> <a href="https://publications.waset.org/abstracts/13055/the-effect-of-aerobic-exercises-on-the-amount-of-urea-uric-acid-and-creatine-in-blood-of-iranian-soccer-players" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/13055.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">534</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17311</span> Body Mass Index, Components of Metabolic Syndrome and Hyperuricemia among Women in Postmenopausal Period</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Vladyslav%20Povoroznyuk">Vladyslav Povoroznyuk</a>, <a href="https://publications.waset.org/abstracts/search?q=Galina%20Dubetska"> Galina Dubetska</a>, <a href="https://publications.waset.org/abstracts/search?q=Roksolana%20Povoroznyuk"> Roksolana Povoroznyuk</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In recent years, the problem of hyperuricemia is getting a particular importance due to its increased incidence in the world population. The aim of this study was to determine uriс acid level in blood serum, incidence of hyperuricemia among women in postmenopausal period and their association with body mass index and some components of metabolic syndrome (triglyceride, cholesterol, systolic and diastolic pressure). We examined 412 women in postmenopausal period. They were divided in to the following groups: I group (BMI = 18,5-24,9), II group (BMI = 25,0-29,9), III group (BMI = 30,0-34,9), IV group (BMI > 35). We determined uric acid level among women during postmenopausal period depending on their body mass index. The higher level of uric acid was found in patients with the maximal body mass index (BMI > 35). In the I group it was 277,52 ± 8,40; in the II group – 286,81 ± 7,79; in the III group – 291,81 ± 7,56; in the IV group – 327,17 ± 12,17. Incidence of hyperuricemia among women in the I group was 10,2%, in the II group – 15,9%; in the III group – 21,2%, in the IV group – 34,2%. We found an interdependence between an uric acid level and BMI in the examined women (r = 0,21, p < 0,05). We determined that the highest level of triglyceride (F = 18,62, p < 0,05), cholesterol (F = 3,64, p < 0,05), atherogenic coefficient (F = 22,64, p < 0,05), systolic (F = 10,5, p < 0,05) and diastolic pressure (F = 4,30, p < 0,05) was among women with hyperuricemia. It was an interdependence between an uric acid level and triglyceride (r = 0,26, p < 0,05), atherogenic coefficient (r = 0,24, p < 0,05) among women in postmenopausal period. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hyperuricemia" title="hyperuricemia">hyperuricemia</a>, <a href="https://publications.waset.org/abstracts/search?q=uric%20acid" title=" uric acid"> uric acid</a>, <a href="https://publications.waset.org/abstracts/search?q=body%20mass%20index" title=" body mass index"> body mass index</a>, <a href="https://publications.waset.org/abstracts/search?q=women" title=" women"> women</a> </p> <a href="https://publications.waset.org/abstracts/116571/body-mass-index-components-of-metabolic-syndrome-and-hyperuricemia-among-women-in-postmenopausal-period" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/116571.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">130</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17310</span> Determination of Bisphenol A and Uric Acid by Modified Single-Walled Carbon Nanotube with Magnesium Layered Hydroxide 3-(4-Methoxyphenyl)Propionic Acid Nanocomposite </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Illyas%20Md%20Isa">Illyas Md Isa</a>, <a href="https://publications.waset.org/abstracts/search?q=Maryam%20Musfirah%20Che%20Sobry"> Maryam Musfirah Che Sobry</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamad%20Syahrizal%20Ahmad"> Mohamad Syahrizal Ahmad</a>, <a href="https://publications.waset.org/abstracts/search?q=Nurashikin%20Abd%20Azis"> Nurashikin Abd Azis</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A single-walled carbon nanotube (SWCNT) that has been modified with magnesium layered hydroxide 3-(4-methoxyphenyl)propionic acid nanocomposite was proposed for the determination of uric acid and bisphenol A by square wave voltammetry. The results obtained denote that MLH-MPP nanocomposites enhance the sensitivity of the voltammetry detection responses. The best performance is shown by the modified carbon nanotube paste electrode (CNTPE) with the composition of single-walled carbon nanotube: magnesium layered hydroxide 3-(4-methoxyphenyl)propionic acid nanocomposite at 100:15 (% w/w). The linear range where the sensor works well is within the concentration 1.0 10-7 – 1.0 10-4 and 3.0 10-7 – 1.0 10-4 for uric acid and bisphenol A respectively with the limit of detection of 1.0 10-7 M for both organics. The interferences of uric acid and bisphenol A with other organic were studied and most of them did not interfere. The results shown for each experimental parameter on the proposed CNTPE showed that it has high sensitivity, good selectivity, repeatability and reproducibility. Therefore, the modified CNTPE can be used for the determination of uric acid and bisphenol A in real samples such as blood, plastic bottles and foods. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bisphenol%20A" title="bisphenol A">bisphenol A</a>, <a href="https://publications.waset.org/abstracts/search?q=magnesium%20layered%20hydroxide%203-%284-methoxyphenyl%29propionic%20acid%20nanocomposite" title=" magnesium layered hydroxide 3-(4-methoxyphenyl)propionic acid nanocomposite"> magnesium layered hydroxide 3-(4-methoxyphenyl)propionic acid nanocomposite</a>, <a href="https://publications.waset.org/abstracts/search?q=Nanocomposite" title=" Nanocomposite"> Nanocomposite</a>, <a href="https://publications.waset.org/abstracts/search?q=uric%20acid" title=" uric acid"> uric acid</a> </p> <a href="https://publications.waset.org/abstracts/84874/determination-of-bisphenol-a-and-uric-acid-by-modified-single-walled-carbon-nanotube-with-magnesium-layered-hydroxide-3-4-methoxyphenylpropionic-acid-nanocomposite" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/84874.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">212</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17309</span> Microfluidic Paper-Based Electrochemical Biosensor</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ahmad%20Manbohi">Ahmad Manbohi</a>, <a href="https://publications.waset.org/abstracts/search?q=Seyyed%20Hamid%20Ahmadi"> Seyyed Hamid Ahmadi </a> </p> <p class="card-text"><strong>Abstract:</strong></p> A low-cost paper-based microfluidic device (PAD) for the multiplex electrochemical determination of glucose, uric acid, and dopamine in biological fluids was developed. Using wax printing, PAD containing a central zone, six channels, and six detection zones was fabricated, and the electrodes were printed on detection zones using pre-made electrodes template. For each analyte, two detection zones were used. The carbon working electrode was coated with chitosan-BSA (and enzymes for glucose and uric acid). To detect glucose and uric acid, enzymatic reactions were employed. These reactions involve enzyme-catalyzed redox reactions of the analytes and produce free electrons for electrochemical measurement. Calibration curves were linear (R<sup>²</sup> > 0.980) in the range of 0-80 mM for glucose, 0.09–0.9 mM for dopamine, and 0–50 mM for uric acid, respectively. Blood samples were successfully analyzed by the proposed method. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biological%20fluids" title="biological fluids">biological fluids</a>, <a href="https://publications.waset.org/abstracts/search?q=biomarkers" title=" biomarkers"> biomarkers</a>, <a href="https://publications.waset.org/abstracts/search?q=microfluidic%20paper-based%20electrochemical%20biosensors" title="microfluidic paper-based electrochemical biosensors">microfluidic paper-based electrochemical biosensors</a>, <a href="https://publications.waset.org/abstracts/search?q=Multiplex" title=" Multiplex"> Multiplex</a> </p> <a href="https://publications.waset.org/abstracts/77212/microfluidic-paper-based-electrochemical-biosensor" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/77212.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">282</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17308</span> Effect of High Dose of Vitamin C in Reduction Serum Uric Acid: a Comparative Study between Hyperuricemic and Gouty Patients in Jeddah </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Firas%20S.%20Azzeh">Firas S. Azzeh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Vitamin C is a water soluble vitamin that is necessary for normal growth and development. Hyperuricemia is commonly detected in subjects with abnormal purine metabolism. Prolonged hyperuricemia is an important risk factor for damaged joint and often associated with gout. Objectives: To compare the effect of high dose of vitamin C supplements on uric acid treatment between hyperuricemic and gouty patients in Jeddah, Saudi Arabia, as well as finding out the effect of vitamin C on serum creatinine level and glomerular filtration rate (GFR). Subjects and Methods: This comparative study started on April 2013 and lasted tells March 2014. A convenience sample of 30 adults was recruited in this study from Doctor Abdulrahman Taha Bakhsh Hospital in Jeddah (Saudi Arabia). Eligible persons were assigned into two study groups; hyperuricemic (n=15) and gouty (n=15) groups. Subjects have been accepted for participating in the study after completing the consent form. Each participant consumed 500 mg/day vitamin C chew able tablets. All participants have been followed-up for 2 months. Twelve hours fasting blood samples have been collected 3 times from each participant during the study period; at the beginning before and retested after each month of the study period. Uric acid, serum creatinine and GFR were measured. Results: For gouty group, uric acid increased insignificantly after 2 months by about +0.3 mg/dl. On the other hand, hyperuricemic group showed decrease (P ≤ 0.05) in uric acid after 2 months of study period by about -0.78 mg/dl. Serum creatinine level insignificantly decreased for all participants during the study period, which leaded to insignificant increase in GFR for all participants. Conclusion: Supplementation with 500 mg/day vitamin C for 2 months significantly reduced serum uric acid for hyperuricemic patients and insignificantly increased serum uric acid for gouty patients. The ineffectiveness of vitamin C supplements on patients with established gout could be related to a number of potential reasons. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=vitamin%20c" title="vitamin c">vitamin c</a>, <a href="https://publications.waset.org/abstracts/search?q=Hyperuricemia" title=" Hyperuricemia"> Hyperuricemia</a>, <a href="https://publications.waset.org/abstracts/search?q=gout" title=" gout"> gout</a>, <a href="https://publications.waset.org/abstracts/search?q=creatinine" title=" creatinine"> creatinine</a>, <a href="https://publications.waset.org/abstracts/search?q=GFR" title=" GFR "> GFR </a> </p> <a href="https://publications.waset.org/abstracts/17621/effect-of-high-dose-of-vitamin-c-in-reduction-serum-uric-acid-a-comparative-study-between-hyperuricemic-and-gouty-patients-in-jeddah" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/17621.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">386</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17307</span> A Sensitive Uric Acid Electrochemical Sensing in Biofluids Based on Ni/Zn Hydroxide Nanocatalyst</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nathalia%20Florencia%20Barros%20Azeredo">Nathalia Florencia Barros Azeredo</a>, <a href="https://publications.waset.org/abstracts/search?q=Josu%C3%A9%20%20Martins%20Gon%C3%A7alves"> Josué Martins Gonçalves</a>, <a href="https://publications.waset.org/abstracts/search?q=Pamela%20%20De%20Oliveira%20Rossini"> Pamela De Oliveira Rossini</a>, <a href="https://publications.waset.org/abstracts/search?q=Koiti%20Araki"> Koiti Araki</a>, <a href="https://publications.waset.org/abstracts/search?q=Lucio%20%20Angnes"> Lucio Angnes</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This work demonstrates the electroanalysis of uric acid (UA) at very low working potential (0 V vs Ag/AgCl) directly in body fluids such as saliva and sweat using electrodes modified with mixed -Ni0.75Zn0.25(OH)2 nanoparticles exhibiting stable electrocatalytic responses from alkaline down to weakly acidic media (pH 14 to 3 range). These materials were prepared for the first time and fully characterized by TEM, XRD, and spectroscopic techniques. The electrochemical properties of the modified electrodes were evaluated in a fast and simple procedure for uric acid analyses based on cyclic voltammetry and chronoamperometry, pushing down the detection and quantification limits (respectively of 2.3*10-8 and 7.6*10-8 mol L-1) with good repeatability (RSD = 3.2% for 30 successive analyses pH 14). Finally, the possibility of real application was demonstrated upon realization of unexpectedly robust and sensitive modified FTO (fluorine doped tin oxide) glass and screen-printed sensors for measurement of uric acid directly in real saliva and sweat samples, with no significant interference of usual concentrations of ascorbic acid, acetaminophen, lactate and glucose present in those body fluids (Fig. 1). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=nickel%20hydroxide" title="nickel hydroxide">nickel hydroxide</a>, <a href="https://publications.waset.org/abstracts/search?q=mixed%20catalyst" title=" mixed catalyst"> mixed catalyst</a>, <a href="https://publications.waset.org/abstracts/search?q=uric%20acid%20sensors" title=" uric acid sensors"> uric acid sensors</a>, <a href="https://publications.waset.org/abstracts/search?q=biofluids" title=" biofluids"> biofluids</a> </p> <a href="https://publications.waset.org/abstracts/121329/a-sensitive-uric-acid-electrochemical-sensing-in-biofluids-based-on-nizn-hydroxide-nanocatalyst" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/121329.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">127</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17306</span> Relationship between Prolonged Timed up and Go Test and Worse Cardiometabolic Diseases Risk Factors Profile in a Population Aged 60-65 Years</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bart%C5%82omiej%20K.%20So%C5%82tysik">Bartłomiej K. Sołtysik</a>, <a href="https://publications.waset.org/abstracts/search?q=Agnieszka%20Guligowska"> Agnieszka Guligowska</a>, <a href="https://publications.waset.org/abstracts/search?q=%C5%81ukasz%20Kroc"> Łukasz Kroc</a>, <a href="https://publications.waset.org/abstracts/search?q=Ma%C5%82gorzata%20Pig%C5%82owska"> Małgorzata Pigłowska</a>, <a href="https://publications.waset.org/abstracts/search?q=Elizavetta%20Fife"> Elizavetta Fife</a>, <a href="https://publications.waset.org/abstracts/search?q=Tomasz%20Kostka"> Tomasz Kostka</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Functional capacity is one of the basic determinants of health in older age. Functional capacity may be influenced by multiple disorders, including cardiovascular and metabolic diseases. Nevertheless, there is relatively little evidence regarding the association of functional status and cardiometabolic risk factors. Aim: The aim of this research is to check possible association between functional capacity and cardiovascular risk factor in a group of younger seniors. Materials and Methods: The study group consisted of 300 participants aged 60-65 years (50% were women). Total cholesterol (TC), triglycerides (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), glucose, uric acid, body mass index (BMI), waist-to-height ratio (WHtR) and blood pressure were measured. Smoking status and physical activity level (by Seven Day Physical Activity Recall Questionnaire ) were analysed. Functional status was assessed with the Timed Up and Go (TUG) Test. The data were compared according to gender, and then separately for both sexes regarding prolonged TUG score (>7 s). The limit of significance was set at p≤0.05 for all analyses. Results: Women presented with higher serum lipids and longer TUG. Men had higher blood pressure, glucose, uric acid, the prevalence of hypertension and history of heart infarct. In women group, those with prolonged TUG displayed significantly higher obesity rate (BMI, WHTR), uric acid, hypertension and ischemic heart disease (IHD), but lower physical activity level, TC or LDL-C. Men with prolonged TUG were heavier smokers, had higher TG, lower HDL and presented with higher prevalence of diabetes and IHD. Discussion: This study shows association between functional status and risk profile of cardiometabolic disorders. In women, the relationship of lower functional status to cardiometabolic diseases may be mediated by overweight/obesity. In men, locomotor problems may be related to smoking. Higher education level may be considered as a protective factor regardless of gender. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cardiovascular%20risk%20factors" title="cardiovascular risk factors">cardiovascular risk factors</a>, <a href="https://publications.waset.org/abstracts/search?q=functional%20capacity" title=" functional capacity"> functional capacity</a>, <a href="https://publications.waset.org/abstracts/search?q=TUG%20test" title=" TUG test"> TUG test</a>, <a href="https://publications.waset.org/abstracts/search?q=seniors" title=" seniors"> seniors</a> </p> <a href="https://publications.waset.org/abstracts/60679/relationship-between-prolonged-timed-up-and-go-test-and-worse-cardiometabolic-diseases-risk-factors-profile-in-a-population-aged-60-65-years" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/60679.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">287</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17305</span> Simultaneous Detection of Dopamine and Uric Acid in the Presence of Ascorbic Acid at Physiological Level Using Anodized Multiwalled Carbon Nanotube–Poldimethylsiloxane Paste Electrode</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Angelo%20Gabriel%20Buenaventura">Angelo Gabriel Buenaventura</a>, <a href="https://publications.waset.org/abstracts/search?q=Allan%20Christopher%20Yago"> Allan Christopher Yago</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A carbon paste electrode (CPE) composed of Multiwalled Carbon Nanotube (MWCNT) conducting particle and Polydimethylsiloxane (PDMS) binder was used for simultaneous detection of Dopamine (DA) and Uric Acid (UA) in the presence of Ascorbic Acid (AA) at physiological level. The MWCNT-PDMS CPE was initially activated via potentiodynamic cycling in a basic (NaOH) solution, which resulted in enhanced electrochemical properties. Electrochemical Impedance Spectroscopy measurements revealed a significantly lower charge transfer resistance (Rct) for the OH--activated MWCNT-PDMS CPE (Rct = 5.08kΩ) as compared to buffer (pH 7)-activated MWCNT-PDMS CPE (Rct = 25.9kΩ). Reversibility analysis of Fe(CN)63-/4- redox couple of both Buffer-Activated CPE and OH--Activated CPE showed that the OH—Activated CPE have peak current ratio (Ia/Ic) of 1.11 at 100mV/s while 2.12 for the Buffer-Activated CPE; this showed an electrochemically reversible behavior for Fe(CN)63-/4- redox couple even at relatively fast scan rate using the OH--activated CPE. Enhanced voltammetric signal for DA and significant peak separation between DA and UA was obtained using the OH--activated MWCNT-PDMS CPE in the presence of 50 μM AA via Differential Pulse Voltammetry technique. The anodic peak currents which appeared at 0.263V and 0.414 V were linearly increasing with increasing concentrations of DA and UA, respectively. The linear ranges were obtained at 25 μM – 100 μM for both DA and UA. The detection limit was determined to be 3.86 μM for DA and 5.61 μM for UA. These results indicate a practical approach in the simultaneous detection of important bio-organic molecules using a simple CPE composed of MWCNT and PDMS with base anodization as activation technique. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=anodization" title="anodization">anodization</a>, <a href="https://publications.waset.org/abstracts/search?q=ascorbic%20acid" title=" ascorbic acid"> ascorbic acid</a>, <a href="https://publications.waset.org/abstracts/search?q=carbon%20paste%20electrodes" title=" carbon paste electrodes"> carbon paste electrodes</a>, <a href="https://publications.waset.org/abstracts/search?q=dopamine" title=" dopamine"> dopamine</a>, <a href="https://publications.waset.org/abstracts/search?q=uric%20acid" title=" uric acid"> uric acid</a> </p> <a href="https://publications.waset.org/abstracts/65212/simultaneous-detection-of-dopamine-and-uric-acid-in-the-presence-of-ascorbic-acid-at-physiological-level-using-anodized-multiwalled-carbon-nanotube-poldimethylsiloxane-paste-electrode" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/65212.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">284</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17304</span> Nephroprotective Activity of Aqueous Methanolic Extract of Aerva Lanata (Busehri Booti) against Cisplatin Induced Nephrotoxicity in Rats</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohd%20Aslam%20Aslam">Mohd Aslam Aslam</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Chronic renal failure is a debilitating condition responsible for high morbidity and mortality. Because of its costs and the complexity of its treatment, proper care is available to very few patients in India. According to researchers, the number of adults aged 30 or older who have chronic kidney disease is projected to increase from 13.2 percent currently, to 14.4 percent in 2020 and 16.7 percent in 2030. The aerial part of Aerva lanata (Busehri booti) have been used in kidney disorders by the Unani physicians. In the present study, the effect of extract of Aerva lanata was investigated on cisplatin-induced nephrotoxicity in rats. The renal effects of this drug was evaluated by monitoring levels of blood urea nitrogen (BUN), serum creatinine, serum uric acid in blood and histopathological examination of kidney. Aerva lanata was evaluated at two different doses (1400 mg/kg and 2800 mg/kg). The effect of higher dose was more pronounced in terms of inhibition in the rise of BUN, serum creatinine and uric acid. Higher dose show greater prevention in the rise of BUN, serum creatinine, and uric acid. The histopathological examination of the kidney tissue of the rats treated with aqueous methanolic extract of Aerva lanata (Higher dose-2800 mg/kg) showed marked inhibition of glomerular congestion, tubular casts, peritubular congestion, epithelial desquamation, blood vessel congestion, interstitial edema and inflammatory cells produced by the cisplatin-induced nephrotoxicity. This finding clearly indicates the protective role of Aerva lanata at higher dose. Present investigation validates the use of Aerva lanata in kidney disorders by Unani physicians. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aerva%20lanata" title="Aerva lanata">Aerva lanata</a>, <a href="https://publications.waset.org/abstracts/search?q=Busehri%20booti" title=" Busehri booti"> Busehri booti</a>, <a href="https://publications.waset.org/abstracts/search?q=nephroprotective" title=" nephroprotective"> nephroprotective</a>, <a href="https://publications.waset.org/abstracts/search?q=unani%20medicine" title=" unani medicine"> unani medicine</a> </p> <a href="https://publications.waset.org/abstracts/62873/nephroprotective-activity-of-aqueous-methanolic-extract-of-aerva-lanata-busehri-booti-against-cisplatin-induced-nephrotoxicity-in-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/62873.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">229</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17303</span> Effect of Different Levels of Dried Citrus Sinensis Peel on Blood Parameters of Broilers</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Abbas%20Ebrahimi">Abbas Ebrahimi</a>, <a href="https://publications.waset.org/abstracts/search?q=Zohreh%20Pourhossein"> Zohreh Pourhossein</a>, <a href="https://publications.waset.org/abstracts/search?q=Nariman%20Miraalami"> Nariman Miraalami</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The experiment was conducted to evaluate the effects of different levels of dried citrus sinensis peel (DCSP) on the blood parameters of broilers. Four hundred Ross 308 strain day old broiler in a completely randomized design with five treatments (four replicates per treatment and each replicate had 20 chicks) were categorized. Each treatment used either regulatory diet including 1.5% and 3% DCSP in the base diet and in two periods of 1st to 21st day and 1st to 42nd day and base diet without any additive for six weeks. Data analysis was performed using SAS software and mean comparison was conducted by Duncan method. The results determined that using different level of DCSP has significant effects on blood plasma parameters (P<0.05). Cholesterol, glucose, triglyceride, low density lipoprotein (LDL) at the rearing period was significantly influenced by experimental treatments (P<0.05). However, uric acid, alkaline phosphatase and high density lipoprotein (HDL) was not affected by experimental treatments (P>0.05). The lowest rate of blood cholesterol was concerned to the treatment which was used 3% DCSP 1st to 42nd day and the highest mean of blood cholesterol were concerned to the control treatment. The lowest rate of blood triglyceride was concerned to the treatment which was used 3% DCSP 1st to 42nd day and the highest mean of blood triglyceride were concerned to the control treatment. The lowest rate of blood alkaline phosphatase was concerned to the treatment which was used 3% DCSP 1st to 42nd day and the highest mean of blood alkaline phosphatase were concerned to the treatment which was used 3% DCSP 1st to 21st day. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=blood%20parameters" title="blood parameters">blood parameters</a>, <a href="https://publications.waset.org/abstracts/search?q=broilers" title=" broilers"> broilers</a>, <a href="https://publications.waset.org/abstracts/search?q=dried%20citrus%20sinensis%20peel" title=" dried citrus sinensis peel"> dried citrus sinensis peel</a>, <a href="https://publications.waset.org/abstracts/search?q=regulatory%20diet" title=" regulatory diet "> regulatory diet </a> </p> <a href="https://publications.waset.org/abstracts/10083/effect-of-different-levels-of-dried-citrus-sinensis-peel-on-blood-parameters-of-broilers" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/10083.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">560</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17302</span> Effect of Seasonal Variation on Two Introduced Columbiformes in Awba Dam Tourism Centre, University of Ibadan, Ibadan</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kolawole%20F.%20Farinloye">Kolawole F. Farinloye</a>, <a href="https://publications.waset.org/abstracts/search?q=Samson%20O.%20Ojo"> Samson O. Ojo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Two Columbiformes species were recently introduced to the newly established Awba Dam Tourism Centre [ADTC], hence there is need to investigate the effect of seasonal variation on these species with respect to hematological composition. Blood samples were obtained from superficial ulna vein of the 128 apparently healthy C. livia and C. guinea into tubes containing EDTA as anticoagulant. Thin blood smears (TBS) were prepared, stained and viewed under microscope. Values of Red Blood Cell (RBC) count, White Blood Cell (WBC) count, cholesterol (CH), Uric Acid (UA), Protein (PR), Mean Corpuscular Volume (MCV), Haemoglobin Content (HB), Blood Volume (BV), Plasma Glucose (PG) and Length/Width (L/W) ratio of red blood cells were assessed. The procedure was carried out on a seasonal basis (wet and dry seasons of 2013-2014). Data was analyzed using descriptive and inferential statistics. Lymphocyte count for C. livia was F3, 161 = 13.15, while for C. guinea was F3, 178 = 13.15. Heterophil, H/L ratio and Muscle score values for both species were (rs = -0.38, rs = -0.44), (rs = 0.51, rs = 0.31) (4, 3) respectively. Analyses also demonstrated a low WBC to RBC ratio (0.004: 25.3) in both species during the wet season compared to dry season, respectively. L/W varied significantly among sampling seasons i.e. wet (19.1% of BV, 12.6% of BV, 0.1% of BV) and dry (18.9% of BV, 12.7% of BV, 0.08% of BV). The level of HB in wet season (19.20±8.46108) is lower compared to dry season (19.70±8.48762). T-test also showed (wet=15.625, 0.111), (dry=12.125, 0.146) respectively, hence there is no association between species and haematological parameters. Species introduced were found to be haematologically stable. Although there were slight differences in seasonal composition, however this can be attributed to seasonal variation; suggesting little or no effect of seasons on their blood composition. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=seasonal%20variation" title="seasonal variation">seasonal variation</a>, <a href="https://publications.waset.org/abstracts/search?q=Columbiformes" title=" Columbiformes"> Columbiformes</a>, <a href="https://publications.waset.org/abstracts/search?q=Awba%20Dam%20tourism%20centre" title=" Awba Dam tourism centre"> Awba Dam tourism centre</a>, <a href="https://publications.waset.org/abstracts/search?q=University%20of%20Ibadan" title=" University of Ibadan"> University of Ibadan</a>, <a href="https://publications.waset.org/abstracts/search?q=Ibadan" title=" Ibadan"> Ibadan</a> </p> <a href="https://publications.waset.org/abstracts/71108/effect-of-seasonal-variation-on-two-introduced-columbiformes-in-awba-dam-tourism-centre-university-of-ibadan-ibadan" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/71108.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">341</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17301</span> Estimation of Microbial-N Supply to Small Intestine in Angora Goats Fed by Different Roughage Sources</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nurcan%20Cetinkaya">Nurcan Cetinkaya</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of the study was to estimate the microbial-N flow to small intestine based on daily urinary purine derivatives(PD) mainly xanthine, hypoxanthine, uric acid and allantoin excretion in Angora goats fed by grass hay and concentrate (Period I); barley straw and concentrate (Period II). Daily urine samples were collected during last 3 days of each period from 10 individually penned Angora bucks( LW 30-35 Kg, 2-3 years old) receiving ad libitum grass hay or barley straw and 300 g/d concentrate. Fresh water was always available. 4N H2SO4 was added to collected daily urine .samples to keep pH under 3 to avoid of uric acid precipitation. Diluted urine samples were stored at -20°C until analysis. Urine samples were analyzed for xanthine, hypoxanthine, uric acid, allantoin and creatinine by High-Performance Liquid Chromatographic Method (HPLC). Urine was diluted 1:15 in ratio with water and duplicate samples were prepared for HPLC analysis. Calculated mean levels (n=60) for urinary xanthine, hypoxanthine, uric acid, allantoin, total PD and creatinine excretion were 0.39±0.02 , 0.26±0.03, 0.59±0.06, 5.91±0.50, 7.15±0.57 and 3.75±0.40 mmol/L for Period I respectively; 0.35±0.03, 0.21±0.02, 0.55±0.05, 5.60±0.47, 6.71±0.46 and 3.73±0.41 mmol/L for Period II respectively.Mean values of Period I and II were significantly different (P< 0.05) except creatinine excretion. Estimated mean microbial-N supply to the small intestine for Period I and II in Angora goats were 5.72±0.46 and 5.41±0.61 g N/d respectively. The effects of grass hay and barley straw feeding on microbial-N supply to small intestine were found significantly different (P< 0.05). In conclusion, grass hay showed a better effect on the ruminal microbial protein synthesis compared to barley straw, therefore; grass hay is suggested as roughage source in Angora goat feeding. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=angora%20goat" title="angora goat">angora goat</a>, <a href="https://publications.waset.org/abstracts/search?q=HPLC%20method" title=" HPLC method"> HPLC method</a>, <a href="https://publications.waset.org/abstracts/search?q=microbial-N%20supply%20to%20small%20intestine" title=" microbial-N supply to small intestine"> microbial-N supply to small intestine</a>, <a href="https://publications.waset.org/abstracts/search?q=urinary%20purine%20derivatives" title=" urinary purine derivatives"> urinary purine derivatives</a> </p> <a href="https://publications.waset.org/abstracts/54369/estimation-of-microbial-n-supply-to-small-intestine-in-angora-goats-fed-by-different-roughage-sources" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/54369.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">223</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17300</span> Protective Effect of N-Acetyl Cysteine and Alpha Lipoic Acid on Rats Chronically Exposed to Cadmium Chloride</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=S.%20El%20Ballal">S. El Ballal</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20El%20Sabbagh"> H. El Sabbagh</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Abd%20El%20Gaber"> M. Abd El Gaber</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Eisa"> A. Eisa</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Al%20Gamal"> A. Al Gamal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Cadmium is one of the most harmful heavy metals able to induce severe injury. In this study, sixty four male Sprague Dawley rats weighing (70-80 gm) were used. Rats were divided into 4 groups each group of 16 rats. Group A: served as control and received commercial ration and distilled water Group B: cadmium chloride was administered orally in water at dose of 300 ppm cadmium (560 mg/L as CdCl2). Group C: Animals received cadmium in drinking water in addition to administration of N-acetylcysteine (NAC) orally at a dose of 150 mg/kg body weight, equivalent to 1500 ppm in food. Group D: Animals received cadmium in drinking water in addition to administration of alpha lipoic acid (ALA) orally at a dose of 150 mg/kg body weight, equivalent to 1500 ppm in food. The experiment was continued for 2 months. Collection of blood and tissue samples was performed at 2, 4, 6, 8 weeks. Blood sample were collected for serum biochemical analysis including malondialdehyde (MDA), total antioxidants, aspartate aminotransferase (AST), alanine aminotransferase (ALT), total protein, albumin, urea and uric acid. Tissue specimens were collected for histopathological examination including liver, kidney, brain and testis. Histopathological examination revealed that cadmium choloride induces pathological alterations which increased in severity with time. The use of NAC and ALA can ameliorate toxic effect of CdCl2. The results showed significant decrease MDA and significant increase total antioxidants in group C and D compared to group B, Liver enzymes include AST and ALT showed significant decrease. Regarding to results of total protein and albumin, they revealed significant increase. Urea and uric acid showed significant decrease. From our study we conclude that NAC and ALA have protective effect against cadmium toxicity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ALA" title="ALA">ALA</a>, <a href="https://publications.waset.org/abstracts/search?q=cadmium" title=" cadmium"> cadmium</a>, <a href="https://publications.waset.org/abstracts/search?q=histopathology" title=" histopathology"> histopathology</a>, <a href="https://publications.waset.org/abstracts/search?q=NAC" title=" NAC"> NAC</a> </p> <a href="https://publications.waset.org/abstracts/42239/protective-effect-of-n-acetyl-cysteine-and-alpha-lipoic-acid-on-rats-chronically-exposed-to-cadmium-chloride" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/42239.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">338</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17299</span> Kinetics of Inhibition of Xanthine Oxidase by Lycium Arabicum and Its Protective Effect against Oxonate-Induced Hyperuricemia and Renal Dysfunction in Mice</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Naouel%20Boussoualim">Naouel Boussoualim</a>, <a href="https://publications.waset.org/abstracts/search?q=Hayat%20Trabsa"> Hayat Trabsa</a>, <a href="https://publications.waset.org/abstracts/search?q=Imane%20Krache"> Imane Krache</a>, <a href="https://publications.waset.org/abstracts/search?q=Seddik%20Khennouf"> Seddik Khennouf</a>, <a href="https://publications.waset.org/abstracts/search?q=Noureddine%20Charef"> Noureddine Charef</a>, <a href="https://publications.waset.org/abstracts/search?q=Lekhmici%20Arrar"> Lekhmici Arrar</a>, <a href="https://publications.waset.org/abstracts/search?q=Abderrahmane%20Baghiani"> Abderrahmane Baghiani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Purpose: To evaluate the in-vitro inhibition of xanthine oxidase (purified from bovine milk) by extracts of Lycium arabicum, as well as it is in vivo hypouricemic and renal protective effects. Methods: Four extracts of Lycium arabicum, methanol (CrE), chloroform (ChE), ethyl acetate (EaE) and aqueous (AqE) extracts, were screened for their total phenolics and potential inhibitory effects on purified bovine milk xanthine oxidase (XO) activity by measuring the formation of uric acid or superoxide radical. The mode of inhibition was investigated and compared with the standard drugs, allopurinol, quercitin, and catechin. To evaluate their hypouricemic effect, the extracts were administered to potassium oxonate-induced hyperuricemic mice at a dose of 50 mg/kg body weight. Results: The results showed that EaE had the highest content of phenolic compounds and was the most potent inhibitor of uric acid formation (IC50 = 0.017 ± 0.001 mg/mL) and formation of superoxide (IC50 = 0.035 ± 0.001 mg/ml). Lineweaver-Burk analysis showed that CrE and EaE inhibited XO competitively, whereas the inhibitory activities exerted by ChE and AqE were of a mixed type. Intraperetoneal injection of L. arabicum extracts (50 mg/kg) elicited hypouricemic actions in hyperuricemic mice. Hyperuricemic mice presented a serum uric acid concentration of 4.71 ± 0.29 mg/L but this was reduced to 1.78 ± 0.11 mg/L by EaE, which was the most potent hyporuricemic extract. Conclusion: L. arabicum fractions have a strong inhibitory effect on xanthine oxidase and and also have a significantly lowering effect on serum and liver creatinine and urea levels in hyperuricemic mice. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=lycium%20arabicum" title="lycium arabicum">lycium arabicum</a>, <a href="https://publications.waset.org/abstracts/search?q=uric%20acid" title=" uric acid"> uric acid</a>, <a href="https://publications.waset.org/abstracts/search?q=creatinine" title=" creatinine"> creatinine</a>, <a href="https://publications.waset.org/abstracts/search?q=superoxide" title=" superoxide"> superoxide</a>, <a href="https://publications.waset.org/abstracts/search?q=phenolic%20compounds" title=" phenolic compounds"> phenolic compounds</a>, <a href="https://publications.waset.org/abstracts/search?q=flavonoids" title=" flavonoids"> flavonoids</a>, <a href="https://publications.waset.org/abstracts/search?q=hyperuricemia" title=" hyperuricemia"> hyperuricemia</a> </p> <a href="https://publications.waset.org/abstracts/41766/kinetics-of-inhibition-of-xanthine-oxidase-by-lycium-arabicum-and-its-protective-effect-against-oxonate-induced-hyperuricemia-and-renal-dysfunction-in-mice" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/41766.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">395</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17298</span> The Influence of Newest Generation Butyrate Combined with Acids, Medium Chain Fatty Acids and Plant Extract on the Performance and Physiological State of Laying Hens</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Vilma%20Sasyte">Vilma Sasyte</a>, <a href="https://publications.waset.org/abstracts/search?q=Vilma%20Viliene"> Vilma Viliene</a>, <a href="https://publications.waset.org/abstracts/search?q=Asta%20Raceviciute-Stupeliene"> Asta Raceviciute-Stupeliene</a>, <a href="https://publications.waset.org/abstracts/search?q=Agila%20Dauksiene"> Agila Dauksiene</a>, <a href="https://publications.waset.org/abstracts/search?q=Romas%20Gruzauskas"> Romas Gruzauskas</a>, <a href="https://publications.waset.org/abstracts/search?q=Virginijus%20Slausgalvis"> Virginijus Slausgalvis</a>, <a href="https://publications.waset.org/abstracts/search?q=Jamal%20Al-Saifi"> Jamal Al-Saifi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of the present study was to investigate the effect of butyrate, acids, medium-chain fatty acids and plant extract mixture on performance, blood and gastrointestinal tract characteristics of laying hens’. For the period of 8 weeks, 24 Hisex Brown laying hens were randomly assigned to 2 dietary treatments: 1) control wheat-corn-soybean meal based diet (Control group), 2) control diet supplemented with the mixture of butyrate, acids, medium chain fatty acids and plant extract (Lumance®) at the level of 1.5 g/kg of feed (Experimental group). Hens were fed with a crumbled diet at 125 g per day. Housing and feeding conditions were the same for all groups and met the requirements of growth for laying hens of Hisex Brown strain. In the blood serum total protein, bilirubin, cholesterol, DTL- and MTL- cholesterol, triglycerides, glucose, GGT, GOT, GPT, alkaline phosphatase, alpha amylase, contents of c-reactive protein, uric acid, and lipase were analyzed. Development of intestines and internal organs (intestinal length, intestinal weight, the weight of glandular and muscular stomach, pancreas, heart, and liver) were determined. The concentration of short chain fatty acids in caecal content was measured using the method of HPLC. The results of the present study showed that 1.5 g/kg supplementation of feed additive affected egg production and feed conversion ratio for the production of 1 kg of egg mass. Dietary supplementation of analyzed additive in the diets increased the concentration of triglycerides, GOT, alkaline phosphatase and decreased uric acid content compared with the control group (P<0.05). No significant difference for others blood indices in comparison to the control was observed. The addition of feed additives in laying hens’ diets increased intestinal weight by 11% and liver weight by 14% compared with the control group (P<0.05). The short chain fatty acids (propionic, acetic and butyric acids) in the caecum of laying hens in experimental groups decreased compared with the control group. The supplementation of the mixture of butyrate, acids, medium-chain fatty acids and plant extract at the level of 1.5 g/kg in the laying hens’ diets had the effect on the performance, some gastrointestinal tract function and blood parameters of laying hens. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=acids" title="acids">acids</a>, <a href="https://publications.waset.org/abstracts/search?q=butyrate" title=" butyrate"> butyrate</a>, <a href="https://publications.waset.org/abstracts/search?q=laying%20hens" title=" laying hens"> laying hens</a>, <a href="https://publications.waset.org/abstracts/search?q=MCFA" title=" MCFA"> MCFA</a>, <a href="https://publications.waset.org/abstracts/search?q=performance" title=" performance"> performance</a>, <a href="https://publications.waset.org/abstracts/search?q=plant%20extract" title=" plant extract"> plant extract</a>, <a href="https://publications.waset.org/abstracts/search?q=psysiological%20state" title=" psysiological state"> psysiological state</a> </p> <a href="https://publications.waset.org/abstracts/64278/the-influence-of-newest-generation-butyrate-combined-with-acids-medium-chain-fatty-acids-and-plant-extract-on-the-performance-and-physiological-state-of-laying-hens" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/64278.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">296</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17297</span> Renoprotective Effect of Alcoholic Extract of Bacopa monnieri via Inhibition of Advanced Glycation End Products and Oxidative Stress in Stz-Nicotinamide Induced Diabetic Nephropathy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Lalit%20Kishore">Lalit Kishore</a>, <a href="https://publications.waset.org/abstracts/search?q=Randhir%20Singh"> Randhir Singh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Diabetic nephropathy (DN) is the major cause of morbidity among diabetic patients. In this study, the effect of Bacopa monnieri Linn. (Brahmi, BM), was studied in a Streptozotocin (STZ)-induced experimental rat model of DN. Diabetic nephropathy was induced in Male Wistar rats (body weight- 300± 10 gms) by single intra-peritoneal injection of STZ (45mg/kg, i.p.) after 15 min of Nicotinamide (230 mg/kg) administration. Different doses of alcoholic extract i.e. 100, 200 and 400 mg/kg was given for 45 days by oral gavage after induction of DN. Blood glucose level, serum insulin, glycosylated haemoglobin, renal parameters (serum urea, uric acid, creatinine and BUN) and lipid profile (total cholesterol, triglycerides, HDL, LDL and VLDL levels) were measured. Concentration of thiobarbituric acid reactive species (TBARS) and levels of antioxidant enzymes of reduced glutathione (GSH), superoxide dismutase (SOD), and catalase (CAT) were evaluated in the kidney, liver and pancreas. At the end of treatment period the alcoholic extract of BM reduced the elevated level of blood glucose, serum insulin, renal parameters, lipid levels, TBARS, AGE’s in kidney and significantly increased body weight, HDL and antioxidant enzymes in dose dependent manner as compared to diabetic control animals. These results suggested the BM possesses significant renoprotective activity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=AGE%27s" title="AGE's">AGE's</a>, <a href="https://publications.waset.org/abstracts/search?q=lipid%20profile" title=" lipid profile"> lipid profile</a>, <a href="https://publications.waset.org/abstracts/search?q=oxidative%20stress" title=" oxidative stress"> oxidative stress</a>, <a href="https://publications.waset.org/abstracts/search?q=renal%20parameters" title=" renal parameters"> renal parameters</a> </p> <a href="https://publications.waset.org/abstracts/43175/renoprotective-effect-of-alcoholic-extract-of-bacopa-monnieri-via-inhibition-of-advanced-glycation-end-products-and-oxidative-stress-in-stz-nicotinamide-induced-diabetic-nephropathy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/43175.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">322</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17296</span> Identification of Some Factors Influencing Serum Uric Acid Concentration in Individuals With Metabolic Syndrome</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Munkhtuul%20G.">Munkhtuul G.</a>, <a href="https://publications.waset.org/abstracts/search?q=Bolortsetseg%20Z."> Bolortsetseg Z.</a>, <a href="https://publications.waset.org/abstracts/search?q=Lutzul%20M."> Lutzul M.</a>, <a href="https://publications.waset.org/abstracts/search?q=Sugar%20N."> Sugar N.</a>, <a href="https://publications.waset.org/abstracts/search?q=Nyamdorj%20D."> Nyamdorj D.</a>, <a href="https://publications.waset.org/abstracts/search?q=Nomundari%20B."> Nomundari B.</a>, <a href="https://publications.waset.org/abstracts/search?q=Zesemdorj%20O."> Zesemdorj O.</a>, <a href="https://publications.waset.org/abstracts/search?q=Erdenebayar%20N."> Erdenebayar N.</a>, <a href="https://publications.waset.org/abstracts/search?q=Lkhagvasuren%20T.%20S."> Lkhagvasuren T. S.</a>, <a href="https://publications.waset.org/abstracts/search?q=Munkhbayarlakh%20S."> Munkhbayarlakh S.</a>, <a href="https://publications.waset.org/abstracts/search?q=Bayasgalan%20T.%20Uurtuya%20S.%20H."> Bayasgalan T. Uurtuya S. H.</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Elevated serum uric acid (SUA) levels are observed in metabolic and cardiovascular conditions as an early predictor of metabolic syndrome (MS). Hyperuricemia, characterised by high uric acid levels in serum, increases the risk of developing MS by 1.6 times. Being overweight and obese significantly contributes to developing MS and cardiovascular disorders. In Mongolia, the prevalence of overweight and obesity is reaching 48.8% among individuals aged 15 to 49 years, indicating a potential surge in the incidence of MS, cardiovascular disorders, diabetes mellitus, and gout.Objective: This study aimed to determine the SUA levels in men diagnosed with MS and investigate the factors influencing these levels.Methods: A total of 119 men aged 30-60, who underwent preventive examinations and resided in Ulaanbaatar city, were included in the study. The criteria established by the International Diabetes Federation (IDF), American Heart Association (AHA), and the National Heart, Lung, and Blood Institute (NHLBI) were employed to define metabolic syndrome. Hyperuricemia was defined as SUA levels ≥7 mg/dL. Dietary intake was evaluated through the 24-hour recall method.Results: The study revealed that the prevalence of MS among the participants was 42.9% (n=51), with hyperuricemia observed in 16.8% (n=20) of the individuals. Among men diagnosed with MS, 21.3% (n=10) exhibited hyperuricemia. The mean SUA levels were as follows: 4.7±0.8 mg/dL in the healthy group, 5.9±1.1 mg/dL in men without MS but presenting central obesity, and 6.2±1.3 mg/dL in men with MS. After adjusting for age and body mass index (BMI), a positive correlation was observed between SUA levels and triglycerides (β=0.93) as well as lipid accumulation product (LAP) (β=0.92) in men with MS. In the central obesity group, SUA levels exhibited a positive correlation with triglycerides (β=0.91), visceral adiposity index (VAI) (β=0.73), LAP (β=0.92), and cardiometabolic index (CMI) (β=0.69). The risk of hyperuricemia increased by 3.29 times with elevated triglycerides and 3.53 times with an increased LAP.Conclusion: The findings indicate that abdominal fat accumulation, as indicated by elevated triglyceride levels and LAP, is associated with increased SUA levels in men with MS. However, no significant relationship was observed between SUA levels and dietary intake. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=central%20obesity" title="central obesity">central obesity</a>, <a href="https://publications.waset.org/abstracts/search?q=obesity" title=" obesity"> obesity</a>, <a href="https://publications.waset.org/abstracts/search?q=triglycerides" title=" triglycerides"> triglycerides</a>, <a href="https://publications.waset.org/abstracts/search?q=hyperuricemia" title=" hyperuricemia"> hyperuricemia</a> </p> <a href="https://publications.waset.org/abstracts/171363/identification-of-some-factors-influencing-serum-uric-acid-concentration-in-individuals-with-metabolic-syndrome" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/171363.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">62</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17295</span> Fe Modified Tin Oxide Thin Film Based Matrix for Reagentless Uric Acid Biosensing</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kashima%20Arora">Kashima Arora</a>, <a href="https://publications.waset.org/abstracts/search?q=Monika%20Tomar"> Monika Tomar</a>, <a href="https://publications.waset.org/abstracts/search?q=Vinay%20Gupta"> Vinay Gupta</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Biosensors have found potential applications ranging from environmental testing and biowarfare agent detection to clinical testing, health care, and cell analysis. This is driven in part by the desire to decrease the cost of health care and to obtain precise information more quickly about the health status of patient by the development of various biosensors, which has become increasingly prevalent in clinical testing and point of care testing for a wide range of biological elements. Uric acid is an important byproduct in human body and a number of pathological disorders are related to its high concentration in human body. In past few years, rapid growth in the development of new materials and improvements in sensing techniques have led to the evolution of advanced biosensors. In this context, metal oxide thin film based matrices due to their bio compatible nature, strong adsorption ability, high isoelectric point (IEP) and abundance in nature have become the materials of choice for recent technological advances in biotechnology. In the past few years, wide band-gap metal oxide semiconductors including ZnO, SnO₂ and CeO₂ have gained much attention as a matrix for immobilization of various biomolecules. Tin oxide (SnO₂), wide band gap semiconductor (Eg =3.87 eV), despite having multifunctional properties for broad range of applications including transparent electronics, gas sensors, acoustic devices, UV photodetectors, etc., it has not been explored much for biosensing purpose. To realize a high performance miniaturized biomolecular electronic device, rf sputtering technique is considered to be the most promising for the reproducible growth of good quality thin films, controlled surface morphology and desired film crystallization with improved electron transfer property. Recently, iron oxide and its composites have been widely used as matrix for biosensing application which exploits the electron communication feature of Fe, for the detection of various analytes using urea, hemoglobin, glucose, phenol, L-lactate, H₂O₂, etc. However, to the authors’ knowledge, no work is being reported on modifying the electronic properties of SnO₂ by implanting with suitable metal (Fe) to induce the redox couple in it and utilizing it for reagentless detection of uric acid. In present study, Fe implanted SnO₂ based matrix has been utilized for reagentless uric acid biosensor. Implantation of Fe into SnO₂ matrix is confirmed by energy-dispersive X-Ray spectroscopy (EDX) analysis. Electrochemical techniques have been used to study the response characteristics of Fe modified SnO₂ matrix before and after uricase immobilization. The developed uric acid biosensor exhibits a high sensitivity to about 0.21 mA/mM and a linear variation in current response over concentration range from 0.05 to 1.0 mM of uric acid besides high shelf life (~20 weeks). The Michaelis-Menten kinetic parameter (Km) is found to be relatively very low (0.23 mM), which indicates high affinity of the fabricated bioelectrode towards uric acid (analyte). Also, the presence of other interferents present in human serum has negligible effect on the performance of biosensor. Hence, obtained results highlight the importance of implanted Fe:SnO₂ thin film as an attractive matrix for realization of reagentless biosensors towards uric acid. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Fe%20implanted%20tin%20oxide" title="Fe implanted tin oxide">Fe implanted tin oxide</a>, <a href="https://publications.waset.org/abstracts/search?q=reagentless%20uric%20acid%20biosensor" title=" reagentless uric acid biosensor"> reagentless uric acid biosensor</a>, <a href="https://publications.waset.org/abstracts/search?q=rf%20sputtering" title=" rf sputtering"> rf sputtering</a>, <a href="https://publications.waset.org/abstracts/search?q=thin%20film" title=" thin film"> thin film</a> </p> <a href="https://publications.waset.org/abstracts/79005/fe-modified-tin-oxide-thin-film-based-matrix-for-reagentless-uric-acid-biosensing" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/79005.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">181</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17294</span> Impact of Saline Water and Water Restriction in Laying Hens</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Reza%20Vakili">Reza Vakili</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This experiment was conducted to investigate the effect of duration water restriction of drinking water and salinity level on production performance, egg quality and biochemical and hematological blood indices of laying hens. A total of 240 Hy-Line laying hens were used in a completely randomized design with a 2 × 2 factorial arrangement of treatments. Experimental treatments were: 1) free access to drinking water and a low level of salinity (TDS below 500 mg/L) (FAW+LS), 2) free access to water and a high level of salinity (TDS above 1500 mg/L), (FAW+HS), 3) 12 h nightly water restriction and a low level of salinity (LAW+LS), and 4) 12 h water restriction and a high level of salinity (LAW+HS). Intake of feed, percentage of egg production and egg weight and mass were not affected by water restriction or salinity level (P > 0.05), however, a trend (P < 0.01) for lower water consumption was detected in water-restricted hens, regardless of salinity level (213 vs 187). A tendency for lower eggshell and yolk weights was observed in hens that had limited access to water with high salinity compared to those had free access to high saline water (P = 0.08). Serum total protein and glucose concentrations significantly reduced (P < 0.05) in hens drank high salinity water, regardless of water restriction. Moreover, saline water increased the concentration of uric acid, creatinine, and cholesterol when compared to low salinity drank-hens (P < 0.05). The concentrations of ALT and AST increased with salinity level (P < 0.05) and water restriction caused an increment in AST content (P < 0.05). In conclusion, Hy-Line laying hens could withstand water restriction, whilst could not tolerate water salinity of about 1500 mg/L. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chemical%20pollutants" title="chemical pollutants">chemical pollutants</a>, <a href="https://publications.waset.org/abstracts/search?q=eggs" title=" eggs"> eggs</a>, <a href="https://publications.waset.org/abstracts/search?q=laying%20hens" title=" laying hens"> laying hens</a>, <a href="https://publications.waset.org/abstracts/search?q=salinity" title=" salinity"> salinity</a>, <a href="https://publications.waset.org/abstracts/search?q=water%20quality" title=" water quality"> water quality</a> </p> <a href="https://publications.waset.org/abstracts/191494/impact-of-saline-water-and-water-restriction-in-laying-hens" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/191494.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">23</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17293</span> Allopurinol Prophylactic Therapy in the Prevention of Contrast Induced Nephropathy in High Risk Patients Undergoing Coronary Angiography: A Prospective Randomized Controlled Trial</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Seyed%20Fakhreddin%20Hejazi">Seyed Fakhreddin Hejazi</a>, <a href="https://publications.waset.org/abstracts/search?q=Leili%20Iranirad"> Leili Iranirad</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Sadeghi"> Mohammad Sadeghi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohsen%20Talebizadeh"> Mohsen Talebizadeh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Contrast-induced nephropathy (CIN) remains to be a potentially serious complication of radiographic procedures. We performed this clinical trial to assess the preventive effect of allopurinol against CIN in high-risk patients undergoing coronary angiography. Methods: In this prospective randomized controlled trial, 140 patients with at least two risk factors for CIN undergoing coronary angiography were randomly assigned to either the allopurinol group or the control group. Patients in the allopurinol group received 300 mg allopurinol 24 hours before a procedure and intravenous hydration for 12 hours before and after coronary angiography, whereas patients in the control group received intravenous hydration. Serum creatinine (SCr), blood urea nitrogen (BUN) and uric acid were measured before contrast exposure and at 48 hours. CIN was defined as an increase of 25% in serum creatinine (SCr) or >0.5 mg/dl 48 hours after contrast administration. Results: CIN occurred in 11 out of 70 (7.9%) patients in the control group and in 8 out of 70 (5.7%) patients in the allopurinol group. There was no significant difference in the incidence of CIN between the two groups at 48 hours after administering the radiocontrast agent (p = 0.459). However, there were significant differences between the two groups in SCr, BUN, uric acid, and eGFR 48 hours after radiocontrast administration (p < 0.05). Conclusion: Our findings revealed that allopurinol had no substantial efficacy over hydration protocol in high-risk patients for the development of CIN. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=contrast-induced%20nephropathy" title="contrast-induced nephropathy">contrast-induced nephropathy</a>, <a href="https://publications.waset.org/abstracts/search?q=allopurinol" title=" allopurinol"> allopurinol</a>, <a href="https://publications.waset.org/abstracts/search?q=coronary%20angiography" title=" coronary angiography"> coronary angiography</a>, <a href="https://publications.waset.org/abstracts/search?q=contrast%20agent" title=" contrast agent"> contrast agent</a> </p> <a href="https://publications.waset.org/abstracts/53315/allopurinol-prophylactic-therapy-in-the-prevention-of-contrast-induced-nephropathy-in-high-risk-patients-undergoing-coronary-angiography-a-prospective-randomized-controlled-trial" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/53315.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">247</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17292</span> Impact of Environmental Changes on Blood Parameters in the Pelophylax ridibundus</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Murat%20Tosunoglu">Murat Tosunoglu</a>, <a href="https://publications.waset.org/abstracts/search?q=Cigdem%20Gul"> Cigdem Gul</a>, <a href="https://publications.waset.org/abstracts/search?q=Nurcihan%20Hacioglu"> Nurcihan Hacioglu</a>, <a href="https://publications.waset.org/abstracts/search?q=Nurdan%20Tepeova"> Nurdan Tepeova</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Amphibian and Reptilian species are influenced by pollution and habitat destruction. Blood parameters of Amphibia species were particularly affected by the negative environmental conditions. Studied frog samples 36 clinically normal Pelophylax ridibundus individuals were captured along the Biga Stream between April–June 2014. When comparing our findings with the Turkish legislation (Water pollution control regulation), the 1. Locality of the Biga stream in terms of total coliform classified as "high quality water" (Coliform: 866.66 MPN/100 mL), while the 2. locality was a "contaminated water" (Coliform: 53266.66 MPN/100 mL). Blood samples of the live specimens were obtained in the laboratory within one day of their capture. The blood samples were taken from the etherized frogs by means of ventriculus punctures, via heparinized hematocrit capillaries. Hematological and biochemical analyses based on high quality water and contaminated water, respectively, are as follows: Red blood cell count (444210.52-426846.15 per cubic millimeter of blood), white blood cell count (4215.78-4684.61 per cubic millimeter of blood), hematocrit value (29.25-29.43 %), hemoglobin concentration (7.76-7.22 g/dl), mean corpuscular volume (637.64-719.99 fl), mean corpuscular hemoglobin (184.78-174.75 pg), mean corpuscular hemoglobin concentration (29.44-24.82 %), glucose (103.74-124.13 mg/dl), urea (87.68-81.72 mg/L), cholesterol (148.20-197.39 mg/dl), creatinine (0.29-0.28 mg/dl), uric acid (10.26-7.55 mg/L), albumin (1.13-1.39 g/dl), calcium (11.45-9.70 mg/dl), triglyceride (135.23-155.85 mg/dl), total protein (4.26-3.73 g/dl), phosphorus (6.83-17.86 mg/dl), and magnesium (0.95-1.06 mg/dl). The some hematological parameters in P. ridibundus specimens are given for the first time in this study. No water quality dependent variation was observed in clinic hematology parameters measured. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Pelophylax%20ridibundus" title="Pelophylax ridibundus">Pelophylax ridibundus</a>, <a href="https://publications.waset.org/abstracts/search?q=hematological%20parameters" title=" hematological parameters"> hematological parameters</a>, <a href="https://publications.waset.org/abstracts/search?q=biochemistry" title=" biochemistry"> biochemistry</a>, <a href="https://publications.waset.org/abstracts/search?q=freshwater%20quality" title=" freshwater quality "> freshwater quality </a> </p> <a href="https://publications.waset.org/abstracts/27291/impact-of-environmental-changes-on-blood-parameters-in-the-pelophylax-ridibundus" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/27291.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">370</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17291</span> Effects of Cinnamon, Garlic, and Yucca Extracts on Growth Performance and Serum Biochemical Parameters in Broilers</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Anguo%20Chen">Anguo Chen</a>, <a href="https://publications.waset.org/abstracts/search?q=Huajie%20Chen"> Huajie Chen</a>, <a href="https://publications.waset.org/abstracts/search?q=Caimei%20Yang"> Caimei Yang</a>, <a href="https://publications.waset.org/abstracts/search?q=Qihua%20Hong"> Qihua Hong</a>, <a href="https://publications.waset.org/abstracts/search?q=Jun%20Feng"> Jun Feng</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The experiment was conducted with 360 one-day-old Avian commercial broilers to study the effects of dietary cinnamon extract (CE), garlic extract (GE) and yucca extract (YE) on growth performance and serum biochemical parameters in broilers. The chickens were randomly divided equally into 4 treatment groups, each group with 3 replications, and received the same basal corn-bean diets included a starter from 1 d to 21 d and then a grower until 42 d, added with recommended dose 250 mg/kg CE, 25 mg/kg GE and 10 mg/kg YE to relevant group, respectively. The birds were kept in a stainless steel net coop each replication with 24 h light and were fed and drunk ad libitum. At 21 d and 42 d of age, 6 chicks were respectively picked out from every group and were bled to collect serum samples and intestinal samples for laboratory analysis. The results showed that the average daily gain (ADG) of CE, GE and YE group were increased by 7.20% (P<0.05), 3.43% (P>0.05) and 4.89% (P>0.05), feed gain ratio (F/G) was improved by 9.71% (P<0.05), 3.40% (P>0.05) and 3.40% (P>0.05) compared with the control, respectively. At 21 d of age, the content of serum urea nitrogen (SUN) and serum uric acid (SUA) and the activity of serum xanthine oxidase (SXO) in CE group were reduced by 35.17% (P<0.01), 13.73% (P<0.01) and 16.33% (P<0.05) compared with the control, respectively. At 42 d of age, SUN and SUA level and SXO activity were lowered by 24.35% (P<0.01), 15.49% (P<0.05) and 23.09% (P<0.01), respectively. The SXO activity in CE group was decreased by 14.86% (P<0.01) and 15.34%(P<0.01) compare with GE and YE group, respectively. Also, adding CE, GE and YE into broiler diets resulted in lower UN and UA level of intestinal contents. It is clear that CE was more significantly decreased the SXO activity and SUA levels than GE and YE, especially at the latter period, thereby it may play a more important role in improving the growth performance of broilers. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cinnamon%20extract" title="cinnamon extract">cinnamon extract</a>, <a href="https://publications.waset.org/abstracts/search?q=broiler" title=" broiler"> broiler</a>, <a href="https://publications.waset.org/abstracts/search?q=growth%20performance" title=" growth performance"> growth performance</a>, <a href="https://publications.waset.org/abstracts/search?q=serum%20uric%20acid" title=" serum uric acid"> serum uric acid</a>, <a href="https://publications.waset.org/abstracts/search?q=serum%20xanthine%20oxidase" title=" serum xanthine oxidase"> serum xanthine oxidase</a> </p> <a href="https://publications.waset.org/abstracts/3707/effects-of-cinnamon-garlic-and-yucca-extracts-on-growth-performance-and-serum-biochemical-parameters-in-broilers" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/3707.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">440</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17290</span> Tranexamic Acid in Prevention of Postpartum Haemorrhage in Elective Cesarean Section</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ajay%20Agrawal">Ajay Agrawal</a>, <a href="https://publications.waset.org/abstracts/search?q=Pravin%20Shah"> Pravin Shah</a>, <a href="https://publications.waset.org/abstracts/search?q=Shailaja%20Chhetri"> Shailaja Chhetri</a>, <a href="https://publications.waset.org/abstracts/search?q=Pappu%20Rijal"> Pappu Rijal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background and Objectives: Postpartum hemorrhage (PPH) is a common and occasionally life-threatening complication of labour. Cesarean section (CS) is associated with more blood loss than vaginal delivery. There is a trend for increasing CS rates in both developed and developing countries. This could increase the risk of morbidity and mortality, especially among anemic women. The objective of this study was to evaluate the effect of preoperative administration of Intravenous Tranexamic Acid (TA) on blood loss during and after elective CS delivery. Materials and Methods: It is a prospective, randomized controlled study. 160 eligible pregnant women of 37 or more POG planned for CS were randomized into two groups either to receive 10ml(1gm) of tranexamic acid intravenously or 10ml of normal saline. Blood loss was measured during and for 24 hours after operation. Results: The mean estimated blood loss was significantly lower in women treated with TA compared with women in the placebo group (392.13 ml ± 10.06 versus 498.69 ml ± 15.87, respectively; p < 0.001). The mean difference in pre-operative and post-operative hemoglobin levels was statistically significant in the tranexamic acid group than in the control group (0.31 ± 0.18 versus 0.79 ± 0.23, respectively; p < 0.001). Conclusion: Pre-operative use of tranexamic acid is associated with reduced blood loss during and after elective cesarean section. In a developing country like ours where PPH is a major threat to the life of the mothers, it seems to be a promising option. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=blood%20loss" title="blood loss">blood loss</a>, <a href="https://publications.waset.org/abstracts/search?q=cesarean%20section" title=" cesarean section"> cesarean section</a>, <a href="https://publications.waset.org/abstracts/search?q=postpartum%20hemorrhage" title=" postpartum hemorrhage"> postpartum hemorrhage</a>, <a href="https://publications.waset.org/abstracts/search?q=tranexamic%20acid" title=" tranexamic acid"> tranexamic acid</a> </p> <a href="https://publications.waset.org/abstracts/74243/tranexamic-acid-in-prevention-of-postpartum-haemorrhage-in-elective-cesarean-section" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/74243.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">270</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17289</span> Olive Oil (Olea europea L.) Protects against Mercury (II) Induced Oxidative Tissue Damage in Rats</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ahlem%20Bahi">Ahlem Bahi</a>, <a href="https://publications.waset.org/abstracts/search?q=Youcef%20Necib"> Youcef Necib</a>, <a href="https://publications.waset.org/abstracts/search?q=Sakina%20Zerizer"> Sakina Zerizer</a>, <a href="https://publications.waset.org/abstracts/search?q=Cherif%20Abdennour"> Cherif Abdennour</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Salah%20Boulakoud"> Mohamed Salah Boulakoud</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Mercury (II) is a highly toxic metal which induces oxidative stress in the body. In this study, we aimed to investigate the possible protective effect of olive oil, an antioxidant agent, against experimental mercury toxicity in rat model. Administration of mercuric chloride induced significant increase in serum: ALT, AST, and LPA activities; interleukine1, interleukine6, tumor necrosis factor α (TNFα), creatinine, urea, and uric acid levels. Mercuric chloride also induced oxidative stress, as indicate by decreased tissue of GSH level, GSH-Px, and GST activities along with increase the level of lipid peroxidation. Furthermore, treatment with mercuric chloride caused a marked elevation of kidney and liver weight and decreased body weight. Virgin olive oil treatment markedly reduced elevated serum: AST, ALT, and LPA activities; interleukine1, interleukine6, tumor necrosis factor α (TNFα), creatinine, urea, and uric acid levels and contracted the deterious effects of mercuric chloride on oxidative stress markers changes caused by HgCl2 in tissue as compared to control group. Our results implicate that mercury induced oxidative damage in liver and kidney tissue protected by virgin olive oil, with its antioxidant effects. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=mercury" title="mercury">mercury</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidant%20enzymes" title=" antioxidant enzymes"> antioxidant enzymes</a>, <a href="https://publications.waset.org/abstracts/search?q=pro-inflammatory%20cytokine" title=" pro-inflammatory cytokine"> pro-inflammatory cytokine</a>, <a href="https://publications.waset.org/abstracts/search?q=virgin%20olive%20oil" title=" virgin olive oil"> virgin olive oil</a>, <a href="https://publications.waset.org/abstracts/search?q=lipid%20peroxidation" title=" lipid peroxidation"> lipid peroxidation</a> </p> <a href="https://publications.waset.org/abstracts/4443/olive-oil-olea-europea-l-protects-against-mercury-ii-induced-oxidative-tissue-damage-in-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/4443.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">360</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17288</span> Antimicrobial and Haemostatic Effect of Chitosan/Polyacrylic Acid Hybrid Membranes</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=F.%20A.%20Abdel-Mohdy">F. A. Abdel-Mohdy</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20K.%20El-Bisi"> M. K. El-Bisi</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Abou-Okeil"> A. Abou-Okeil</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20A.%20Sleem"> A. A. Sleem</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20El-Sabbagh"> S. El-Sabbagh</a>, <a href="https://publications.waset.org/abstracts/search?q=Kawther%20El-Shafei"> Kawther El-Shafei</a>, <a href="https://publications.waset.org/abstracts/search?q=Hoda%20S.%20El-Sayed"> Hoda S. El-Sayed</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20M.%20ElSawy"> S. M. ElSawy </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Chitosan/ polyacrylic acid membranes containing different amounts of Al2(SO4) and/or TiO2 were prepared. The prepared membranes were characterized by measuring mechanical properties, such as tensile strength and elongation at break, swelling properties, antimicrobial properties against gram-positive and gram-negative bacteria and blood clotting. The results obtained indicate that the presence of Al2(SO4) and TiO2 in the membrane formulations have an incremental effect on the antimicrobial properties and blood clotting in albino rate. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Chitosan" title="Chitosan">Chitosan</a>, <a href="https://publications.waset.org/abstracts/search?q=acrylic%20acid" title=" acrylic acid"> acrylic acid</a>, <a href="https://publications.waset.org/abstracts/search?q=antibacterial" title=" antibacterial"> antibacterial</a>, <a href="https://publications.waset.org/abstracts/search?q=blood%20clotting" title=" blood clotting"> blood clotting</a>, <a href="https://publications.waset.org/abstracts/search?q=membrane" title=" membrane"> membrane</a> </p> <a href="https://publications.waset.org/abstracts/33312/antimicrobial-and-haemostatic-effect-of-chitosanpolyacrylic-acid-hybrid-membranes" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/33312.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">489</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17287</span> The Effects of Ellagic Acid on Rat Heart Induced Tobacco Smoke</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nalan%20Kaya">Nalan Kaya</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20Ozlem%20Dabak"> D. Ozlem Dabak</a>, <a href="https://publications.waset.org/abstracts/search?q=Gonca%20Ozan"> Gonca Ozan</a>, <a href="https://publications.waset.org/abstracts/search?q=Elif%20Erdem"> Elif Erdem</a>, <a href="https://publications.waset.org/abstracts/search?q=Enver%20Ozan"> Enver Ozan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> One of the common causes of cardiovascular disease (CVD) is smoking. Moreover, tobacco smoke decreases the amount of oxygen that the blood can carry and increases the tendency for blood clots. Ellagic acid is a powerful antioxidant found especially in red fruits. It was shown to block atherosclerotic process suppressing oxidative stress and inflammation. The aim of this study was to examine the protective effects of ellagic acid against oxidative damage on heart tissues of rats induced by tobacco smoke. Twenty-four male adult (8 weeks old) Spraque-Dawley rats were divided randomly into 4 equal groups: group I (Control), group II (Tobacco smoke), group III (Tobacco smoke + corn oil) and group IV (Tobacco smoke + ellagic acid). The rats in group II, III and IV, were exposed to tobacco smoke 1 hour twice a day for 12 weeks. In addition to tobacco smoke exposure, 12 mg/kg ellagic acid (dissolved in corn oil), was applied to the rats in group IV by oral gavage. An equal amount of corn oil used in solving ellagic acid was applied to the rats by oral gavage in group III. At the end of the experimental period, rats were decapitated. Heart tissues and blood samples were taken. Histological and biochemical analyzes were performed. Vascular congestion, hyperemic areas, inflammatory cell infiltration and increased connective tissue in the perivascular area were observed in tobacco smoke and tobacco smoke + corn oil groups. Increased connective tissue in the perivascular area, hemorrhage and inflammatory cell infiltration were decreased in tobacco smoke + EA group. Group-II GSH level was not changed (significantly), CAT, SOD, GPx activities were significantly higher than group-I. Compared to group-II, group-IV GSH, SOD, CAT, GPx activities were increased, and MDA level was decreased significantly. Group-II and Group-III levels were similar. The results indicate that ellagic acid could protect the heart tissue from the tobacco smoke harmful effects. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ellagic%20acid" title="ellagic acid">ellagic acid</a>, <a href="https://publications.waset.org/abstracts/search?q=heart" title=" heart"> heart</a>, <a href="https://publications.waset.org/abstracts/search?q=rat" title=" rat"> rat</a>, <a href="https://publications.waset.org/abstracts/search?q=tobacco%20smoke" title=" tobacco smoke"> tobacco smoke</a> </p> <a href="https://publications.waset.org/abstracts/74249/the-effects-of-ellagic-acid-on-rat-heart-induced-tobacco-smoke" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/74249.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">224</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17286</span> Poly (Diphenylamine-4-Sulfonic Acid) Modified Glassy Carbon Electrode for Voltammetric Determination of Gallic Acid in Honey and Peanut Samples</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Zelalem%20Bitew">Zelalem Bitew</a>, <a href="https://publications.waset.org/abstracts/search?q=Adane%20Kassa"> Adane Kassa</a>, <a href="https://publications.waset.org/abstracts/search?q=Beyene%20Misgan"> Beyene Misgan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, a sensitive and selective voltammetric method based on poly(diphenylamine-4-sulfonic acid) modified glassy carbon electrode (poly(DPASA)/GCE) was developed for determination of gallic acid. Appearance of an irreversible oxidative peak at both bare GCE and poly(DPASA)/GCE for gallic acid with about three folds current enhancement and much reduced potential at poly(DPASA)/GCE showed catalytic property of the modifier towards oxidation of gallic acid. Under optimized conditions, Adsorptive stripping square wave voltammetric peak current response of the poly(DPASA)/GCE showed linear dependence with gallic acid concentration in the range 5.00 × 10-7 − 3.00 × 10-4 mol L-1 with limit of detection of 4.35 × 10-9. Spike recovery results between 94.62-99.63, 95.00-99.80 and 97.25-103.20% of gallic acid in honey, raw peanut, and commercial peanut butter samples respectively, interference recovery results with less than 4.11% error in the presence of uric acid and ascorbic acid, lower LOD and relatively wider dynamic range than most of the previously reported methods validated the potential applicability of the method based on poly(DPASA)/GCE for determination of gallic acid real samples including in honey and peanut samples. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=gallic%20acid" title="gallic acid">gallic acid</a>, <a href="https://publications.waset.org/abstracts/search?q=diphenyl%20amine%20sulfonic%20acid" title=" diphenyl amine sulfonic acid"> diphenyl amine sulfonic acid</a>, <a href="https://publications.waset.org/abstracts/search?q=adsorptive%20anodic%20striping%20square%20wave%20voltammetry" title=" adsorptive anodic striping square wave voltammetry"> adsorptive anodic striping square wave voltammetry</a>, <a href="https://publications.waset.org/abstracts/search?q=honey" title=" honey"> honey</a>, <a href="https://publications.waset.org/abstracts/search?q=peanut" title=" peanut"> peanut</a> </p> <a href="https://publications.waset.org/abstracts/172221/poly-diphenylamine-4-sulfonic-acid-modified-glassy-carbon-electrode-for-voltammetric-determination-of-gallic-acid-in-honey-and-peanut-samples" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/172221.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">78</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17285</span> Tranexamic Acid in Orthopedic Surgery in Children</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=K.%20Amanzoui">K. Amanzoui</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Erragh"> A. Erragh</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Elharit"> M. Elharit</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Afif"> A. Afif</a>, <a href="https://publications.waset.org/abstracts/search?q=K.%20Elfakhr"> K. Elfakhr</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Kalouch"> S. Kalouch</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Chlilek"> A. Chlilek</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Orthopedic surgery is a provider of pre and postoperative bleeding; patients are exposed to several risks, and different measures are proposed to reduce bleeding during surgery, called the transfusion-sparing method, including tranexamic acid, which has shown its effectiveness in numerous studies. A prospective analytical study in 50 children was carried out in the orthopedic traumatology operating room of the EL HAROUCHI hospital of the CHU IBN ROCHD in Casablanca over a period of six months (April to October 2022). Two groups were randomized: one receiving tranexamic acid (Group A) and a non-receiving control group (Group B). The average age was 10.3 years, of which 58.8% were female. The first type of surgery was thoracolumbar scoliosis (52%). The average preoperative hemoglobin was 12.28 g/dl in group A, against 12.67 g/dl in the control group. There was no significant difference between the two groups (p=0.148). Mean intraoperative bleeding was 396.29 ml in group A versus 412 ml in the control group. No significant difference was observed for this parameter (p=0.632). The average hemoglobin level in the immediate postoperative period in our patients is 10.2 g/dl. In group A, it was 10.95 g/dl versus 10.93 g/dl in group B. At H24 postoperative, the mean hemoglobin value was 10.29 g/dl in group A against 9.5 g/dl in group B. For group A, the blood loss recorded during the first 24 hours was 209.43 ml, against 372 ml in group B, with a significant difference between the two groups (p=0.001). There is no statistically significant difference between the 2 groups in terms of the use of fillers, ephedrine or intraoperative transfusion. While for postoperative transfusion, we note the existence of a statistically significant difference between group A and group B. It is suggested that the use of tranexamic acid is an effective, simple, and low-cost way to limit postoperative blood loss and the need for transfusion. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=tranexamic%20acid" title="tranexamic acid">tranexamic acid</a>, <a href="https://publications.waset.org/abstracts/search?q=blood%20loss" title=" blood loss"> blood loss</a>, <a href="https://publications.waset.org/abstracts/search?q=orthopedic%20surgery" title=" orthopedic surgery"> orthopedic surgery</a>, <a href="https://publications.waset.org/abstracts/search?q=children" title=" children"> children</a> </p> <a href="https://publications.waset.org/abstracts/162335/tranexamic-acid-in-orthopedic-surgery-in-children" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/162335.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right 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