COX4 Recombinant Protein Antigen (NBP2-78718PEP) by Novus, Part of Bio-Techne

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Product Details</h3> <div class="mt-4 py-2 container"> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Source</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> E. coli </div> </div> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Conjugate</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> Unconjugated </div> </div> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Applications</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> Antibody Competition </div> </div> </div> <div class="container"> <div class="row product-data"> <div class="col-lg-6 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4><a href="/t/cox4/proteins-enzymes">View all COX4 Proteins and Enzymes »</a></h4> </div> </div> </div> </div> <div class="border-top border-bottom recommended-products-section" id="recommendation-viewed" data-product_code="NBP2-78718PEP" data-type=viewed></div> <div id="product-specifications" class="bt-pp-border-bottom py-5" data-section="section-base--product-specifications"> <h3>Product Specifications</h3> <div class="mt-4 py-2 container"> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Description</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> <div id="full-description"> A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human COX4. <br><br><p><b>Source:</b><i> E. coli</i><br><br></p><p><b>Amino Acid Sequence:</b> LATRVFSLVGKRAISTSVCVRAHESVVKSEDFSLPAYMDRRDHPLPEVAHVKHLSASQKALKEKEKASWSSLSMDEKVELYRIKFKESFAEMNRGSNEWKT</p><p><b>Fusion Tag: </b>N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)<br><br></p><p><b>This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.</b></p> </div> </div> </div> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Purity</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> >80% by SDS-PAGE and Coomassie blue staining </div> </div> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Predicted Molecular Mass</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> 29 kDa.<br/>Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. </div> </div> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Applications</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> Antibody Competition (10-100 molar excess) </div> </div> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Application Notes</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP2-78718.<p><p>It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.<p><p>For current lot information, including availability, please contact our technical support team click <a href = "mailto: nb-technical@bio-techne.com."> nb-technical@bio-techne.com </a><p><p>For further blocking tide related information and a protocol, click <a href="https://www.novusbio.com/support/blocking-with-immunizing-tide">here</a>. </div> </div> <div class="row product-data"> <div class="col-lg-3 font-weight-bold product-data-label py-2 align-top text-bt-dark-blue"> <h4>Protein / Peptide Type</h4> </div> <div class="col-lg-9 product-data-value py-2 align-top text-break"> Recombinant Protein Antigen </div> </div> </div> </div> <div id="preparation--storage" class="bt-pp-border-bottom py-5" data-section="section-protein--preparation-storage"> <h3>Formulation, Preparation and Storage</h3> <div class="datasheet_section"> <div class="row px-3"> <div class="col-xs-12 "> <div class="border-left border-right border-top text-center"> <h5 class="m-0 p-3 bg-dark-bt-blue text-white"> NBP2-78718PEP </h5> </div> <table class="ds_table_html table-bordered tablesaw tablesaw-stack"> <tbody> <tr> <td class="font-weight-bold">Formulation</td> <td class="w-75">PBS and 1M Urea, pH 7.4.</td> </tr> <tr> <td class="font-weight-bold">Preservative</td> <td class="w-75">No Preservative</td> </tr> <tr> <td class="font-weight-bold">Concentration</td> <td class="w-75">Please see the vial label for concentration. If unlisted please contact technical services.</td> </tr> <tr> <td class="font-weight-bold">Shipping</td> <td class="w-75">The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.</td> </tr> <tr> <td class="font-weight-bold">Stability & Storage</td> <td class="w-75">Store at -20C. Avoid freeze-thaw cycles.</td> </tr> </tbody> </table> </div> </div> </div> </div> <div id="background" class="py-5 bt-pp-border-bottom" data-section="section-base--background-info"> <h3>Background: COX4</h3> <article class="product-data-wrapper"> COX IV (cytochrome c oxidase subunit IV isoform 1) plays a pivotal role in respiratory function and assembly of the enzyme complex. This protein is known to have interactions with MT-CO2, MCL1, TMBIM4, MT-CO1 and TH1L. COX IV has been studied in relation to anemia, Huntington's disease, Alzheimer's disease, neuronitis, pancreatitis and several other diseases and disorders. </article> <div id="background_wrapper" class="px-3 mt-2"> <div class="row product-data"> <div class=" col-md-3 product-data-label font-weight-bold p-3 align-top border"> <h4>Long Name</h4> </div> <div class=" col-md-9 product-data-value p-3 px-4 text-break border"> Cytochrome c Oxidase Subunit IV </div> </div> <div class="row product-data"> <div class=" col-md-3 product-data-label font-weight-bold p-3 align-top border"> <h4>Alternate Names</h4> </div> <div class=" col-md-9 product-data-value p-3 px-4 text-break border"> COX4I2 </div> </div> <div class="row product-data"> <div class=" col-md-3 product-data-label font-weight-bold p-3 align-top border"> <h4>Gene Symbol</h4> </div> <div class=" col-md-9 product-data-value p-3 px-4 text-break border"> COX4I1 </div> </div> </div> <h4 class="mt-3">Additional COX4 Products</h4> <ul class="list-unstyled"> <li><a href="/t/cox4" data-product="COX4">All Products for COX4 </a></li> <li><a href="/t/cox4/lysates" data-application="COX4 Lysates">COX4 Lysates </a></li> <li><a href="/t/cox4/antibodies" data-application="COX4 Primary Antibodies">COX4 Primary Antibodies </a></li> <li><a href="/t/cox4/proteins-enzymes" data-application="COX4 Proteins and Enzymes">COX4 Proteins and Enzymes </a></li> </ul> </div> <div id="product-documents" data-section="section-base--product-documents"> <div id="accordion" class="border mb-4"> <div class="rounded-top bg-white"> <h3 class="m-0 p-3"> Product Documents for COX4 Recombinant Protein Antigen </h3> </div> <div class="vtab-section" data-section="Product Datasheets"> <div class="card-header rounded-top"> <a class="" data-toggle="collapse" data-target="#collapse_two" aria-expanded="true" aria-controls="collapse_two" id="product-datasheets-link"> <h5 class="mb-0"> Product Datasheets </h5> </a> </div> <div id="collapse_two" 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href="https://resources.bio-techne.com/products/documents/sds/NBP2-78718PEP.pdf" class="datasheet_link text-wrap" target="_blank" > Download SDS </a> </div> </div> </div> </div> </div> </div> <div id="specific-notices" class="py-5" data-section="section-base--specific-notices"> <h3>Product Specific Notices for COX4 Recombinant Protein Antigen </h3> <p></p><p>This product is for research use only and is not approved for use in humans or in clinical diagnosis. 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COX4 Recombinant Protein Antigen (NBP2-78718PEP) by Novus, Part of Bio-Techne