Early-Phase Clinical Trials at UCSF: Pediatric Cancer | UCSF Benioff Children's Hospitals

<!DOCTYPE html>     <html class="no-js" lang="en">  <head> <link rel="stylesheet" type="text/css" href=/assets/ucsf/main.css?v=40182074ecb56dad04debd94fedfc468 /> <link rel="stylesheet" type="text/css" href=/assets/bch/main.css?v=754aa12d0b3de52563c5716af1d66516 />  <script type="text/javascript" src="https://cdn.cookielaw.org/consent/69de606f-159b-41ad-82da-d7a76950873b/OtAutoBlock.js" ></script> <script src="https://cdn.cookielaw.org/scripttemplates/otSDKStub.js" type="text/javascript" charset="UTF-8" data-domain-script="69de606f-159b-41ad-82da-d7a76950873b" ></script> <script type="text/javascript"> function OptanonWrapper() { } </script> <script type="text/javascript"> function OptanonWrapper() { // Check if banner div is available if (document.getElementById('onetrust-banner-sdk')) { // Get the buttons and container var acceptBtn = document.getElementById("onetrust-accept-btn-handler"); var declineBtn = document.getElementById("onetrust-reject-all-handler"); var cookieSettingsBtn = document.getElementById("onetrust-pc-btn-handler"); var btnContainer = document.getElementById("onetrust-button-group"); // Set the order you want below... btnContainer.append(acceptBtn, cookieSettingsBtn, declineBtn) } } </script>   <script src="https://datalayer.ucsfhealth.org/ucsf-data-layer.js" defer></script>  <script src="https://datalayer.ucsfhealth.org/ucsfbenioffchildrens-marketing-data-layer.js" defer></script>  <script type="text/plain" class="optanon-category-C0007" src="https://assets.adobedtm.com/db5f13cb240b/b1130ce1ceae/launch-db8f55f3e131.min.js" defer></script> <title>Early-Phase Clinical Trials at UCSF: Pediatric Cancer | UCSF Benioff Children's Hospitals</title> <link href="/-/media/project/ucsf/ucsf-bch/header/favicon-32x32.png?rev=7da17355eec44d65b26747967816d41b" rel="shortcut icon" /> <link rel="canonical" href="https://www.ucsfbenioffchildrens.org/education/cancer-clinical-trials" /> <meta content="Conditions & Treatments" name="mainNavName" /> <meta content="false" name="includeBackgroundCircles" /> <meta property="og:description" content="Our early-phase clinical trials give patients access to promising new therapies for pediatric cancers. Learn more, including how to enroll your child." /><meta property="og:title" content="Early-Phase Clinical Trials at UCSF: Pediatric Cancer" /><meta property="og:url" content="https://www.ucsfbenioffchildrens.org/education/cancer-clinical-trials" /> <meta name="description" content="Our early-phase clinical trials give patients access to promising new therapies for pediatric cancers. Learn more, including how to enroll your child." /> <meta property="twitter:description" content="Our early-phase clinical trials give patients access to promising new therapies for pediatric cancers. Learn more, including how to enroll your child." /><meta property="twitter:title" content="Clinical Trials at UCSF: Pediatric Cancer" /><meta property="twitter:card" content="summary_large_image" /> <meta name="viewport" content="width=device-width, initial-scale=1"/> <link rel="manifest" href="/manifest.json" /> <meta name="format-detection" content="telephone=no"> <script type="application/ld+json"> {"@context":"http://schema.org","@type":"Article","description":"Our early-phase clinical trials give patients access to promising new therapies for pediatric cancers. Learn more, including how to enroll your child.","image":"https://www.ucsfbenioffchildrens.org/-/media/project/ucsf/ucsf-bch/images/education/hero/pediatric-cancer-clinical-trials-at-ucsf-2x.jpg?rev=347d980880314208a751ad17a447790b","url":"https://www.ucsfbenioffchildrens.org/education/cancer-clinical-trials","author":{"@type":"Organization","name":"UCSF Health"},"dateCreated":"2024-03-28T17:05:37+00:00","dateModified":"2024-03-28T17:07:41+00:00","datePublished":"2024-05-14T00:00:00+00:00","publisher":{"@type":"Organization","name":"UCSF Health","logo":{"@type":"ImageObject","url":"https://www.ucsfbenioffchildrens.org/-/media/project/ucsf/ucsf-health/ezgifcom-gif-maker.png?rev=b49aee14cf934fb086632358c341cf97"}},"articleBody":"Standard treatments are effective for many childhood cancers, but some require extra attention or innovation. At UCSF Benioff Children’s Hospitals, we offer our young patients easy access to early-phase clinical trials, which are studies of promising new therapies.\nEnrolling in a clinical trial can provide access to drugs or other treatments that aren’t available anywhere else, offering families hope when their children's previous treatments were unsuccessful. Patients who participate also contribute to scientific research that can help others in the future.\nMany of our doctors lead national research groups working to develop new therapies for brain tumors, leukemia, lymphoma and other cancers that affect children. A dedicated team of nurses and coordinators oversees our clinical trials, ensuring that the data we collect is robust and reliable. What's more, we are the only Northern California hospital to be designated an early-phase clinical trials core site for the Children’s Oncology Group, an organization funded by the National Cancer Institute and dedicated to developing better treatments for pediatric cancers.\nLearn more about the comprehensive care we offer through our Pediatric Cancer Program.\nContact us\nFor more information about a clinical trial, use the links below to express your interest.\nProviders: To refer a patient, please call the appropriate number listed here.\nSan Francisco: (415) 476-3831\nOakland: (510) 428-3372","articleSection":"Patient Education"} </script> </head> <body class="default-device bodyclass"> <a href="#content" class="skip-to-content">Skip to Main Content</a> <div id="wrapper">  <header> <div id="header" class="container-fluid"> <div class="component rich-text ie-warning-banner"> <div class="component-content"> <p> Looks like you’re visiting Benioff Children's Hospitals on Internet Explorer. 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href="/refer-a-patient">Refer a Patient</a></li> </ul> <div class="mobile-nav-footer"> </div> </div> </div> </div> </div> </div> </div> </div> </header>   <main> <div id="content" class="container"> <div class="component article-hero basic-hero"> <div class="component-content"> <div class="hero-image"> <img src="/-/media/project/ucsf/ucsf-bch/images/education/hero/pediatric-cancer-clinical-trials-at-ucsf-2x.jpg?h=1112&iar=0&w=2880&rev=347d980880314208a751ad17a447790b&hash=75694C3116A342D849CC33102D041C13" alt="" width="2880" height="1112" /> </div> <div class="hero-content"> <div class="eyebrow hero-breadcrumb"> <div class="component ucsf-breadcrumb"> <div class="component-content"> <div class="eyebrow article-breadcrumb"> <a href="/education">Patient Education A-Z </a> </div> </div> </div> </div> <div class="hero-badge-hero"> </div> <h1 class="hero-title long-hero-title display1"> Early-Phase Clinical Trials at UCSF: Pediatric Cancer </h1> </div> </div> </div><div class="component share-print-email container clinic-share"> <div class="component-content"> <div class="share-component"> <a aria-label="Print Page" href="#" rel="nofollow" class="icon-ui-print" title="Print"></a> <a aria-label="Share Page" data-email-body="Thought you might want to see this:" class="icon-ui-share" data-email-body="Thought you might want to see this:" data-email-subject="Take a look at this link from UCSF"></a> </div> <div class="clearfix"></div> </div> </div><div class="component article-intro column-layout col-2-66-33 container"> <div class="component-content col-2-80-20"> <div class="article-content left-col"> <div class="article-info-top"> <div class="article-published"> <div class="eyebrow">Published May 2024</div> </div> </div> <div class="font-larger article-text rich-text"> <p>Standard treatments are effective for many childhood cancers, but some require extra attention or innovation. At UCSF Benioff Children’s Hospitals, we offer our young patients easy access to early-phase <a rel="noopener noreferrer" href="https://clinicaltrials.ucsf.edu/browse/pediatric" target="_blank">clinical trials</a>, which are studies of promising new therapies.</p> <p>Enrolling in a clinical trial can provide access to drugs or other treatments that aren’t available anywhere else, offering families hope when their children's previous treatments were unsuccessful. Patients who participate also contribute to scientific research that can help others in the future.</p> <p>Many of our doctors lead national research groups working to develop new therapies for brain tumors, leukemia, lymphoma and other cancers that affect children. A dedicated team of nurses and coordinators oversees our clinical trials, ensuring that the data we collect is robust and reliable. What's more, we are the only Northern California hospital to be designated an early-phase clinical trials core site for the Children’s Oncology Group, an organization funded by the National Cancer Institute and dedicated to developing better treatments for pediatric cancers.</p> <p>Learn more about the comprehensive care we offer through our <a href="/care/cancer">Pediatric Cancer</a> Program.</p> <h2>Contact us</h2> <p>For more information about a clinical trial, use the links below to express your interest.</p> <p>Providers: To refer a patient, please call the appropriate number listed here.<br /> San Francisco: (415) 476-3831<br /> Oakland: (510) 428-3372</p> </div> </div> <div class="article-info right-col"> </div> </div> </div> <div class="component content container"> <div class="component-content"> <div class="page-content"> <div class="component column-layout col-2-66-33 col-xs-12 col-2-80-20"> <div class="component-content"> <div class="left-col"> <div class="component rich-text col-xs-12"> <div class="component-content"> <h2>Active early-phase trials</h2> <h2>Sarcomas and other solid tumors</h2> <table> <tbody> <tr> <td style="width:30%;">PEPN1924</td> <td style="width:70%;"><a rel="noopener noreferrer" href="https://clinicaltrials.ucsf.edu/trial/NCT04616560" target="_blank">Trastuzumab Deruxtecan for the Treatment of HER2+ Newly Diagnosed or Recurrent Osteosarcoma</a></td> </tr> <tr> <td style="width:30%;">PEPN2011</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04851119">Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors</a></td> </tr> <tr> <td style="width:30%;">PEPN2111</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04870944">CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma</a> </td> </tr> <tr> <td style="width:30%;">PEPN2121</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT05286801">Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors</a></td> </tr> <tr> <td style="width:30%;">PNOC026</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04775485">Study to Evaluate DAY101 in Pediatric and Young Adult Patients With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors</a></td> </tr> <tr> <td style="width:30%;">DFCI 19-338</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04134559">Checkpoint Inhibition In Pediatric Hepatocellular Carcinoma</a></td> </tr> <tr> <td style="width:30%;">DFCI 20-041</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04416568">Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers</a></td> </tr> <tr> <td style="width:30%;">DFCI 20-086</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04417062">Olaparib With Ceralasertib in Recurrent Osteosarcoma</a></td> </tr> <tr> <td style="width:30%;">Blueprint ROVER</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04773782">Study of Avapritinib in Pediatric Patients With Solid Tumors Dependent on KIT or PDGFRA Signaling</a></td> </tr> <tr> <td style="width:30%;">Eureka ARYA2</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04634357">ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma</a></td> </tr> <tr> <td style="width:30%;">VAL-10-001</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04337177">Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors</a></td> </tr> </tbody> </table> <h2>Brain Tumors</h2> <table> <tbody> <tr> <td style="width:30%;">Study Nickname</td> <td style="width:70%;"><strong>Study Title</strong></td> </tr> <tr> <td style="width:30%;">PEPN2111</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04870944">CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma</a></td> </tr> <tr> <td style="width:30%;">PEPN2121</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT05286801">Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors</a></td> </tr> <tr> <td style="width:30%;">PNOC017</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT03749187">BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas</a></td> </tr> <tr> <td style="width:30%;">PNOC018</td> <td style="width:70%;"><a rel="noopener noreferrer" href=" https://clinicaltrials.ucsf.edu/trial/NCT05478837" target="_blank">Genetically Modified Cells (KIND T Cells) for the Treatment of HLA-A*0201-Positive Patients With H3.3K27M-Mutated Glioma</a></td> </tr> <tr> <td style="width:30%;">PNOC019</td> <td style="width:70%;"><a rel="noopener noreferrer" href="https://clinicaltrials.ucsf.edu/trial/NCT04323046" target="_blank">Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults</a></td> </tr> <tr> <td style="width:30%;">PNOC021</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04485559">Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas</a></td> </tr> <tr> <td style="width:30%;">PNOC022</td> <td style="width:70%;"><a rel="noopener noreferrer" href=" https://clinicaltrials.ucsf.edu/trial/NCT05009992" target="_blank">Combination Therapy for the Treatment of Diffuse Midline Gliomas</a></td> </tr> <tr> <td style="width:30%;">PNOC023</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04732065">ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors</a></td> </tr> <tr> <td style="width:30%;">PNOC026</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04775485">Study to Evaluate DAY101 in Pediatric and Young Adult Patients With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors</a></td> </tr> <tr> <td style="width:30%;">PNOC027</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT05057702">Individualized Treatment Plan in Children and Young Adults With Relapsed Medulloblastoma</a></td> </tr> <tr> <td style="width:30%;">PNOC029</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT05465174">Nivolumab and DAY101 for Treatment of Craniopharyngioma in Children and Young Adults</a></td> </tr> <tr> <td style="width:30%;">BCC016</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04696029">DFMO as Maintenance Therapy for Molecular High/Very High Risk and Relapsed Medulloblastoma</a></td> </tr> <tr> <td style="width:30%;">DFCI 20-041</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04416568">Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers</a></td> </tr> <tr> <td style="width:30%;">Blueprint ROVER</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04773782">Study of Avapritinib in Pediatric Patients With Solid Tumors Dependent on KIT or PDGFRA Signaling</a></td> </tr> </tbody> </table> <h2>Neuroblastoma</h2> <p><strong>I-MIBG treatment protocols</strong></p> <table border="1" cellspacing="0" cellpadding="0" style="border: none;"> <tbody> <tr> <td style="width:30%;">Study Nickname</td> <td style="width:70%;"><strong>Study Title</strong></td> </tr> <tr> <td style="width:30%;">MIBG 2014-01</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT03561259">A Study of Therapeutic Iobenguane (131-I) and Vorinostat for Recurrent or Progressive High-Risk Neuroblastoma Subjects</a></td> </tr> <tr> <td style="width:30%;">Compassionate-use MIBG CC# 05161</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT01370330">131I-Labeled MIBG for Refractory Neuroblastoma: A Compassionate Use Protocol</a></td> </tr> </tbody> </table> <p /><strong>Non-MIBG protocols</strong><p /> <table border="1" cellspacing="0" cellpadding="0" style="border: none;"> <tbody> <tr> <td style="width:30%;">Study Nickname</td> <td style="width:70%;"><strong>Study Title</strong> </td> </tr> <tr> <td style="width:30%;">ADVL1921</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT03709680">Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors</a></td> </tr> <tr> <td style="width:30%;">PEPN2011</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04851119">Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors</a></td> </tr> <tr> <td style="width:30%;">PEPN2111</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04870944">CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma</a></td> </tr> <tr> <td style="width:30%;">PNOC026</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04775485">Study to Evaluate DAY101 in Pediatric and Young Adult Patients With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors</a></td> </tr> <tr> <td style="width:30%;">BCC015</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04301843">Eflornithine (DFMO) and Etoposide for Relapsed/Refractory Neuroblastoma</a></td> </tr> <tr> <td style="width:30%;">BCC018</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT05489887">Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma</a></td> </tr> <tr> <td style="width:30%;">NMTRC012</td> <td style="width:70%;"><a rel="noopener noreferrer" href="https://clinicaltrials.ucsf.edu/trial/NCT02559778" target="_blank">Pediatric Precision Laboratory Advanced Neuroblastoma Therapy</a></td> </tr> <tr> <td style="width:30%;">NMTRC014</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT02679144">Neuroblastoma Maintenance Therapy Trial</a></td> </tr> <tr> <td style="width:30%;">Blueprint ROVER</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04773782">Study of Avapritinib in Pediatric Patients With Solid Tumors Dependent on KIT or PDGFRA Signaling</a></td> </tr> </tbody> </table> <p> </p> <h2>Leukemia, Lymphoma, Myeloproliferative, and Histiocytic Disorders</h2> <table border="1" cellspacing="0" cellpadding="0" style="border: none;"> <tbody> <tr> <td style="width:30%;">Study Nickname</td> <td style="width:70%;"> <p><strong>Study Title</strong></p> </td> </tr> <tr> <td style="width:30%;">AALL1721</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT03876769">Study of Efficacy and Safety of Tisagenlecleucel in HR B-ALL EOC MRD Positive Patients</a></td> </tr> <tr> <td style="width:30%;">AALL1821</td> <td style="width:70%;"><a rel="noopener noreferrer" href=" https://clinicaltrials.ucsf.edu/trial/NCT04546399" target="_blank">A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)</a></td> </tr> <tr> <td style="width:30%;">AALL1922</td> <td style="width:70%;"><a rel="noopener noreferrer" href=" https://clinicaltrials.ucsf.edu/trial/NCT04501614" target="_blank">A Study of Ponatinib With Chemotherapy in Children, Teenagers, and Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia</a></td> </tr> <tr> <td style="width:30%;">ADVL1822</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT03793478">Safety and Efficacy of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of the Blood</a></td> </tr> <tr> <td style="width:30%;">ANHL2121</td> <td style="width:70%;"><a rel="noopener noreferrer" href="https://clinicaltrials.ucsf.edu/trial/NCT05828069" target="_blank">A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis</a></td> </tr> <tr> <td style="width:30%;">E4412</td> <td style="width:70%;"><a rel="noopener noreferrer" href="https://clinicaltrials.ucsf.edu/trial/NCT01896999" target="_blank">Brentuximab Vedotin and Nivolumab With or Without Ipilimumab in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma</a></td> </tr> <tr> <td style="width:30%;">PEPN2011</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04851119">Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors</a></td> </tr> <tr> <td style="width:30%;">PEPN2111</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT04870944">CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma</a></td> </tr> <tr> <td style="width:30%;">TACL 2020-003</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT05082519">Caloric estriction and Activity to Reduce Chemoresistance in B-ALL</a></td> </tr> <tr> <td style="width:30%;">TACL 2020-006</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT05476770">Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies</a></td> </tr> <tr> <td style="width:30%;">DFCI 21-757</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT05292664">Venetoclax Basket Trial for High Risk Hematologic Malignancies</a></td> </tr> <tr> <td style="width:30%;">NACHO COBI</td> <td style="width:70%;">A Phase 2 Study to Assess the Safety and Efficacy of <strong>Cobimetinib</strong> in Refractory Langerhans Cell Histiocytosis, LCH-Associated Neurodegenerative Disease, and Other Histiocytic Disorders</td> </tr> <tr> <td style="width:30%;">NACHO LCH-IV</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT02205762">LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis</a></td> </tr> <tr> <td style="width:30%;">NYMC575</td> <td style="width:70%;"><a rel="noopener noreferrer" href="https://clinicaltrials.ucsf.edu/trial/NCT03719105" target="_blank">Chemoimmunotherapy and Allogeneic Stem Cell Transplant for NK T-cell Leukemia/Lymphoma</a></td> </tr> <tr> <td style="width:30%;">Genentech C043810</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT05533775">Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma</a></td> </tr> <tr> <td style="width:30%;">SYNDAX-5613-0702 (AUGMENT-102)</td> <td style="width:70%;"><a href="https://clinicaltrials.ucsf.edu/trial/NCT05326516">Study of SNDX-5613 in Combination With Chemotherapy in Participants With R/R Acute Leukemia</a></td> </tr> </tbody> </table> </div> </div> </div> <div class="right-col"> </div> </div> </div> <div class="component numbered-clinic-rollup col-xs-12"> <div class="component-content"> <h2 class="heading1">Related clinics (4)</h2> <div class="cards"> <div class="numbered-clinic-card"> <div class="numbered-clinic-card-first"> <div class="numbered-clinic-card-first-image"> <img loading="lazy" 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src="/-/media/project/ucsf/ucsf-bch/images/clinic/numbered-clinic-card/brain-tumor-center-320x320-2x.jpg?rev=f2a161e70d1d41dbb0a1745b9209a652&hash=321C1BDA9394713A1785D20A01A53A09" alt="" width="640" height="640"> <span>2</span> </div> <h2 class="numbered-clinic-card-header first">Brain Tumor Program</h2> </div> <div class="numbered-clinic-card-second"> <h2 class="numbered-clinic-card-header second">Brain Tumor Program</h2> <div class="numbered-clinic-card-second-locations"> <a href="/clinics/brain-tumor-program" target="_self" title="Brain Tumor Program"></a> <span><p>San Francisco / Oakland</p></span> </div> </div> </div> <div class="numbered-clinic-card"> <div class="numbered-clinic-card-first"> <div class="numbered-clinic-card-first-image"> <img loading="lazy" src="/-/media/project/ucsf/ucsf-bch/images/clinic/numbered-clinic-card/oncology-clinic-320x320-2x.jpg?rev=aefa5d584aa24b6bbf865b4f7b3fe3d7&hash=E86BC5B421E49D97C1D57C84BAE20ABF" alt="oncology-clinic-320x320-2x" width="640" 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