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Deri</title> <meta name="description" content="Search results for: Shani Deri"> <meta name="keywords" content="Shani Deri"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler ml-auto" type="button" data-toggle="collapse" data-target="#navbarMenu" aria-controls="navbarMenu" aria-expanded="false" aria-label="Toggle navigation"> <span class="navbar-toggler-icon"></span> </button> <div class="w-100"> <div class="d-none d-lg-flex flex-row-reverse"> <form method="get" action="https://waset.org/search" class="form-inline my-2 my-lg-0"> <input class="form-control mr-sm-2" type="search" placeholder="Search Conferences" value="Shani Deri" name="q" aria-label="Search"> <button class="btn btn-light my-2 my-sm-0" type="submit"><i class="fas fa-search"></i></button> </form> </div> <div class="collapse navbar-collapse mt-1" id="navbarMenu"> <ul class="navbar-nav ml-auto align-items-center" id="mainNavMenu"> <li class="nav-item"> <a class="nav-link" href="https://waset.org/conferences" title="Conferences in 2024/2025/2026">Conferences</a> </li> <li class="nav-item"> <a class="nav-link" href="https://waset.org/disciplines" title="Disciplines">Disciplines</a> </li> <li 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id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Shani Deri"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 8</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Shani Deri</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">8</span> Structure and Mechanics Patterns in the Assembly of Type V Intermediate-Filament Protein-Based Fibers</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mark%20Bezner">Mark Bezner</a>, <a href="https://publications.waset.org/abstracts/search?q=Shani%20Deri"> Shani Deri</a>, <a href="https://publications.waset.org/abstracts/search?q=Tom%20Trigano"> Tom Trigano</a>, <a href="https://publications.waset.org/abstracts/search?q=Kfir%20Ben-Harush"> Kfir Ben-Harush</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Intermediate filament (IF) proteins-based fibers are among the toughest fibers in nature, as was shown by native hagfish slime threads and by synthetic fibers that are based on type V IF-proteins, the nuclear lamins. It is assumed that their mechanical performance stems from two major factors: (1) the transition from elastic -helices to stiff-sheets during tensile load; and (2) the specific organization of the coiled-coil proteins into a hierarchical network of nano-filaments. Here, we investigated the interrelationship between these two factors by using wet-spun fibers based on C. elegans (Ce) lamin. We found that Ce-lamin fibers, whether assembled in aqueous or alcoholic solutions, had the same nonlinear mechanical behavior, with the elastic region ending at ~5%. The pattern of the transition was, however, different: the ratio between -helices and -sheets/random coils was relatively constant until a 20% strain for fibers assembled in an aqueous solution, whereas for fibers assembled in 70% ethanol, the transition ended at a 6% strain. This structural phenomenon in alcoholic solution probably occurred through the transition between compacted and extended conformation of the random coil, and not between -helix and -sheets, as cycle analyses had suggested. The different transition pattern can also be explained by the different higher order organization of Ce-lamins in aqueous or alcoholic solutions, as demonstrated by introducing a point mutation in conserved residue in Ce-lamin gene that alter the structure of the Ce-lamins’ nano-fibrils. In addition, biomimicking the layered structure of silk and hair fibers by coating the Ce-lamin fiber with a hydrophobic layer enhanced fiber toughness and lead to a reversible transition between -helix and the extended conformation. This work suggests that different hierarchical structures, which are formed by specific assembly conditions, lead to diverse secondary structure transitions patterns, which in turn affect the fibers’ mechanical properties. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=protein-based%20fibers" title="protein-based fibers">protein-based fibers</a>, <a href="https://publications.waset.org/abstracts/search?q=intermediate%20filaments%20%28IF%29%20assembly" title=" intermediate filaments (IF) assembly"> intermediate filaments (IF) assembly</a>, <a href="https://publications.waset.org/abstracts/search?q=toughness" title=" toughness"> toughness</a>, <a href="https://publications.waset.org/abstracts/search?q=structure-property%20relationships" title=" structure-property relationships"> structure-property relationships</a> </p> <a href="https://publications.waset.org/abstracts/155383/structure-and-mechanics-patterns-in-the-assembly-of-type-v-intermediate-filament-protein-based-fibers" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/155383.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">110</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">7</span> To Individualisation of Subject, Donar, by Determination of Serological Markers from Obtain Biological Fluid at Crime Scene</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Arun%20Kumar">Arun Kumar</a>, <a href="https://publications.waset.org/abstracts/search?q=Ravindra%20Pal%20Verma"> Ravindra Pal Verma</a>, <a href="https://publications.waset.org/abstracts/search?q=Harsh%20Sharma"> Harsh Sharma</a>, <a href="https://publications.waset.org/abstracts/search?q=Shani%20Kumar"> Shani Kumar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> For the present study samples was collected from 20 donors with unknown blood group and secretor status had been determined from saliva by using biological fluid. ABO typing on the concentrated samples was successfully performed after 1 month of storage. Urine stained clothing samples are often submitted to forensic science laboratories for ABH blood group antigen determination. The serogenetic markers of semen stains submitted can be used to determine the origin of any of these samples. ABH blood group substances have previously been identified from urine. ABH blood group substance is low in urine in comparison with other body fluids. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ABH%20blood%20group" title="ABH blood group">ABH blood group</a>, <a href="https://publications.waset.org/abstracts/search?q=crime%20scene" title=" crime scene"> crime scene</a>, <a href="https://publications.waset.org/abstracts/search?q=serological%20markers" title=" serological markers"> serological markers</a>, <a href="https://publications.waset.org/abstracts/search?q=body%20fluids%20and%20urine" title=" body fluids and urine"> body fluids and urine</a> </p> <a href="https://publications.waset.org/abstracts/45691/to-individualisation-of-subject-donar-by-determination-of-serological-markers-from-obtain-biological-fluid-at-crime-scene" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/45691.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">587</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6</span> A Change in Psychological Child Development Case Study on Animation Film Tom and Jerry</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shani%20Ruri%20Efendi">Shani Ruri Efendi</a>, <a href="https://publications.waset.org/abstracts/search?q=Lucky%20Tio%20Monika"> Lucky Tio Monika</a>, <a href="https://publications.waset.org/abstracts/search?q=Prita%20Esita"> Prita Esita</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Purpose: The purpose of this paper is to know the negative impact of the animated film show Tom & Jerry, how it might affect the changes of psychological child development, if this affects the development growth of children's behaviour and advice from the case of psychology as a solution to such problems Design/methodology/approach: The paper’s findings are based on an experimental method in conducting the test. The experiment lasted for 6 days at elementary school children aged from 6-7 years. Findings: The results of the analysis can be found that pictorial questionnaire which is one of the test tools in the study had no significant effect and also using IQ test is one test tool in the study of positive and significant influence of television has changed the way of thinking in children. Originality/value: This research tries to dig more into the negative influence of animated film Tom and Jerry as a negative influence on the development of children who may have the implementation of the child's behaviour in life. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=child%20development" title="child development">child development</a>, <a href="https://publications.waset.org/abstracts/search?q=animated%20film" title=" animated film"> animated film</a>, <a href="https://publications.waset.org/abstracts/search?q=Tom%20and%20Jerry" title=" Tom and Jerry"> Tom and Jerry</a>, <a href="https://publications.waset.org/abstracts/search?q=elementary%20school%20children" title=" elementary school children"> elementary school children</a> </p> <a href="https://publications.waset.org/abstracts/34409/a-change-in-psychological-child-development-case-study-on-animation-film-tom-and-jerry" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/34409.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">766</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> Classroom Curriculum That Includes Wisdom Skills</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Brian%20Fleischli">Brian Fleischli</a>, <a href="https://publications.waset.org/abstracts/search?q=Shani%20Robins"> Shani Robins</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In recent years, the implementation of wisdom skills, including emotional intelligence, mindfulness, empathy, compassion, gratitude, realism (Cognitive-Behavioral Therapy), and humility, within K-12 educational settings has demonstrated significant benefits in reducing stress, anxiety, anger, and conflict among students. This study summarizes the findings of research conducted over several years, showcasing the positive outcomes associated with teaching these skills to elementary and high school students. Additionally, this overview includes an updated synthesis of current literature concerning the application and effectiveness of training these skill sets in K-12 schools. The research outcomes highlight substantial improvements in student well-being and behavior. Demonstrated with treatment group students exhibiting notable reductions in anger, anxiety, depression, and disruptive behaviors compared to control groups. For instance, fourth-grade students showed enhanced empathy, responsibility, and attention, particularly benefiting those with lower initial scores on these measures. Specific interaction effects suggest that older students and males particularly benefit from these interventions, showcasing the nuanced impact of wisdom skill training across different demographics. Furthermore, this presentation emphasizes the critical role of Social and Emotional Learning (SEL) programs in addressing the multifaceted challenges faced by children and adolescents, including mental health issues, academic performance, and social behaviors. The integration of wisdom skills into school curricula not only fosters individual growth and emotional regulation but also enhances overall school climate and academic achievement. In conclusion, the findings contribute to the growing body of empirical evidence supporting the efficacy of teaching wisdom skills in educational settings. The success of these interventions underscores the potential for widespread implementation of evidence-based programs to promote emotional well-being and academic success among students nationwide. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=wisdom%20skills" title="wisdom skills">wisdom skills</a>, <a href="https://publications.waset.org/abstracts/search?q=CBT" title=" CBT"> CBT</a>, <a href="https://publications.waset.org/abstracts/search?q=cognitive%20behavioral%20training" title=" cognitive behavioral training"> cognitive behavioral training</a>, <a href="https://publications.waset.org/abstracts/search?q=mindfulness" title=" mindfulness"> mindfulness</a>, <a href="https://publications.waset.org/abstracts/search?q=empathy" title=" empathy"> empathy</a>, <a href="https://publications.waset.org/abstracts/search?q=anxiety" title=" anxiety"> anxiety</a> </p> <a href="https://publications.waset.org/abstracts/186151/classroom-curriculum-that-includes-wisdom-skills" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/186151.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">44</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> The Influence of Infiltration and Exfiltration Processes on Maximum Wave Run-Up: A Field Study on Trinidad Beaches</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shani%20Brathwaite">Shani Brathwaite</a>, <a href="https://publications.waset.org/abstracts/search?q=Deborah%20Villarroel-Lamb"> Deborah Villarroel-Lamb</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Wave run-up may be defined as the time-varying position of the landward extent of the water’s edge, measured vertically from the mean water level position. The hydrodynamics of the swash zone and the accurate prediction of maximum wave run-up, play a critical role in the study of coastal engineering. The understanding of these processes is necessary for the modeling of sediment transport, beach recovery and the design and maintenance of coastal engineering structures. However, due to the complex nature of the swash zone, there remains a lack of detailed knowledge in this area. Particularly, there has been found to be insufficient consideration of bed porosity and ultimately infiltration/exfiltration processes, in the development of wave run-up models. Theoretically, there should be an inverse relationship between maximum wave run-up and beach porosity. The greater the rate of infiltration during an event, associated with a larger bed porosity, the lower the magnitude of the maximum wave run-up. Additionally, most models have been developed using data collected on North American or Australian beaches and may have limitations when used for operational forecasting in Trinidad. This paper aims to assess the influence and significance of infiltration and exfiltration processes on wave run-up magnitudes within the swash zone. It also seeks to pay particular attention to how well various empirical formulae can predict maximum run-up on contrasting beaches in Trinidad. Traditional surveying techniques will be used to collect wave run-up and cross-sectional data on various beaches. Wave data from wave gauges and wave models will be used as well as porosity measurements collected using a double ring infiltrometer. The relationship between maximum wave run-up and differing physical parameters will be investigated using correlation analyses. These physical parameters comprise wave and beach characteristics such as wave height, wave direction, period, beach slope, the magnitude of wave setup, and beach porosity. Most parameterizations to determine the maximum wave run-up are described using differing parameters and do not always have a good predictive capability. This study seeks to improve the formulation of wave run-up by using the aforementioned parameters to generate a formulation with a special focus on the influence of infiltration/exfiltration processes. This will further contribute to the improvement of the prediction of sediment transport, beach recovery and design of coastal engineering structures in Trinidad. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=beach%20porosity" title="beach porosity">beach porosity</a>, <a href="https://publications.waset.org/abstracts/search?q=empirical%20models" title=" empirical models"> empirical models</a>, <a href="https://publications.waset.org/abstracts/search?q=infiltration" title=" infiltration"> infiltration</a>, <a href="https://publications.waset.org/abstracts/search?q=swash" title=" swash"> swash</a>, <a href="https://publications.waset.org/abstracts/search?q=wave%20run-up" title=" wave run-up "> wave run-up </a> </p> <a href="https://publications.waset.org/abstracts/56508/the-influence-of-infiltration-and-exfiltration-processes-on-maximum-wave-run-up-a-field-study-on-trinidad-beaches" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/56508.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">357</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Detecting Tomato Flowers in Greenhouses Using Computer Vision</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Dor%20Oppenheim">Dor Oppenheim</a>, <a href="https://publications.waset.org/abstracts/search?q=Yael%20Edan"> Yael Edan</a>, <a href="https://publications.waset.org/abstracts/search?q=Guy%20Shani"> Guy Shani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper presents an image analysis algorithm to detect and count yellow tomato flowers in a greenhouse with uneven illumination conditions, complex growth conditions and different flower sizes. The algorithm is designed to be employed on a drone that flies in greenhouses to accomplish several tasks such as pollination and yield estimation. Detecting the flowers can provide useful information for the farmer, such as the number of flowers in a row, and the number of flowers that were pollinated since the last visit to the row. The developed algorithm is designed to handle the real world difficulties in a greenhouse which include varying lighting conditions, shadowing, and occlusion, while considering the computational limitations of the simple processor in the drone. The algorithm identifies flowers using an adaptive global threshold, segmentation over the HSV color space, and morphological cues. The adaptive threshold divides the images into darker and lighter images. Then, segmentation on the hue, saturation and volume is performed accordingly, and classification is done according to size and location of the flowers. 1069 images of greenhouse tomato flowers were acquired in a commercial greenhouse in Israel, using two different RGB Cameras – an LG G4 smartphone and a Canon PowerShot A590. The images were acquired from multiple angles and distances and were sampled manually at various periods along the day to obtain varying lighting conditions. Ground truth was created by manually tagging approximately 25,000 individual flowers in the images. Sensitivity analyses on the acquisition angle of the images, periods throughout the day, different cameras and thresholding types were performed. Precision, recall and their derived F1 score were calculated. Results indicate better performance for the view angle facing the flowers than any other angle. Acquiring images in the afternoon resulted with the best precision and recall results. Applying a global adaptive threshold improved the median F1 score by 3%. Results showed no difference between the two cameras used. Using hue values of 0.12-0.18 in the segmentation process provided the best results in precision and recall, and the best F1 score. The precision and recall average for all the images when using these values was 74% and 75% respectively with an F1 score of 0.73. Further analysis showed a 5% increase in precision and recall when analyzing images acquired in the afternoon and from the front viewpoint. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=agricultural%20engineering" title="agricultural engineering">agricultural engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=image%20processing" title=" image processing"> image processing</a>, <a href="https://publications.waset.org/abstracts/search?q=computer%20vision" title=" computer vision"> computer vision</a>, <a href="https://publications.waset.org/abstracts/search?q=flower%20detection" title=" flower detection"> flower detection</a> </p> <a href="https://publications.waset.org/abstracts/57279/detecting-tomato-flowers-in-greenhouses-using-computer-vision" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/57279.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">329</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> The Effect of SIAH1 on PINK1 Homeostasis in Parkinson Disease</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Fatimah%20Abd%20Elghani">Fatimah Abd Elghani</a>, <a href="https://publications.waset.org/abstracts/search?q=Raymonde%20Szargel"> Raymonde Szargel</a>, <a href="https://publications.waset.org/abstracts/search?q=Vered%20Shani"> Vered Shani</a>, <a href="https://publications.waset.org/abstracts/search?q=Hazem%20Safory"> Hazem Safory</a>, <a href="https://publications.waset.org/abstracts/search?q=Haya%20Hamza"> Haya Hamza</a>, <a href="https://publications.waset.org/abstracts/search?q=Mor%20Savyon"> Mor Savyon</a>, <a href="https://publications.waset.org/abstracts/search?q=Ruth%20Rott"> Ruth Rott</a>, <a href="https://publications.waset.org/abstracts/search?q=Rina%20Bandopadhyay"> Rina Bandopadhyay</a>, <a href="https://publications.waset.org/abstracts/search?q=Simone%20Engelender"> Simone Engelender</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: PINK1 is a mitochondrial kinase mutated in some familial cases of Parkinson’s disease. Down regulation of PINK1 results in abnormal mitochondrial morphology and altered membrane potential. Although PINK1 has a predicted mitochondrial import sequence, it’s cellular, and submitochondrial localization remains unclear, in part because it is rapidly degraded. In this work, we investigated the mechanisms involved in PINK1 degradation and how this may affect PINK1 stability and function, with implications for mitochondrial function in PD. In addition, pharmacological inhibition of proteasome activity was shown to lead to PINK1 accumulation, indicating that PINK1 degradation depends on the ubiquitin-proteasome system (UPS). Methods: Using co-immunoprecipitation assays, we identified E3 ubiquitin ligase SIAH1 as a PINK1-interacting protein in HEK293 cells as well as on rat brain tissues. In addition, we determined the effect of SIAH 1, SIAH2 and Parkin on PINK1 steady-state levels by Western blot analysis, and checked their possibility to ubiquitinate and mediate PINK1 degradation through the proteasome carried out in vivo ubiquitination experiments. Results: We have obtained results showing that SIAH-1 interacts with and ubiquitinates PINK1. The ubiquitination promoted by SIAH-1 leads to the proteasomal degradation of PINK1. We confirmed these findings by knocking down SIAH-1 and observing important accumulation of PINK1 in cells. Besides, we found that SIAH-1 decreases PINK1 steady-state levels but not the E3 ligase Parkin. We also investigated the interaction of SIAH-1 with PINK1 disease mutants and its ability to promote their ubiquitination and degradation. Although, no clear difference in the ability of SIAH-1 to promote the degradation of PINK1 disease mutants was observed. It is possible that dysfunction of proteasomal activity in the disease may lead to the accumulation and aggregation of ubiquitinated PINK1 in patients with PINK1 mutations, with possible implications to the pathogenesis of PD. Conclusions: Here, we demonstrated that SIAH-1 ubiquitinates and promotes the degradation of PINK1. In addition, SIAH-1 represents now a target that may help the improvement of mitophagy in PD. Further investigations needed to understand how mitophagy is regulated by PINK1-SIAH-1 axis to provide targets for future therapeutics. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=PD" title="PD">PD</a>, <a href="https://publications.waset.org/abstracts/search?q=Parkinson%27s%20disease" title=" Parkinson's disease"> Parkinson's disease</a>, <a href="https://publications.waset.org/abstracts/search?q=PINK1" title=" PINK1"> PINK1</a>, <a href="https://publications.waset.org/abstracts/search?q=PTEN-induced%20kinase1" title=" PTEN-induced kinase1"> PTEN-induced kinase1</a>, <a href="https://publications.waset.org/abstracts/search?q=SIAH" title=" SIAH"> SIAH</a>, <a href="https://publications.waset.org/abstracts/search?q=seven%20in%20absentia%20homolog" title=" seven in absentia homolog"> seven in absentia homolog</a>, <a href="https://publications.waset.org/abstracts/search?q=SN" title=" SN"> SN</a>, <a href="https://publications.waset.org/abstracts/search?q=substantia%20nigra" title=" substantia nigra"> substantia nigra</a> </p> <a href="https://publications.waset.org/abstracts/110954/the-effect-of-siah1-on-pink1-homeostasis-in-parkinson-disease" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/110954.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">142</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Tele-Rehabilitation for Multiple Sclerosis: A Case Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sharon%20Harel">Sharon Harel</a>, <a href="https://publications.waset.org/abstracts/search?q=Rachel%20Kizony"> Rachel Kizony</a>, <a href="https://publications.waset.org/abstracts/search?q=Yoram%20Feldman"> Yoram Feldman</a>, <a href="https://publications.waset.org/abstracts/search?q=Gabi%20Zeilig"> Gabi Zeilig</a>, <a href="https://publications.waset.org/abstracts/search?q=Mordechai%20Shani"> Mordechai Shani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Multiple Sclerosis (MS) is a neurological disease that may cause restriction in participation in daily activities of young adults. Main symptoms include fatigue, weakness and cognitive decline. The appearance of symptoms, their severity and deterioration rate, change between patients. The challenge of health services is to provide long-term rehabilitation services to people with MS. The objective of this presentation is to describe a course of tele-rehabilitation service of a woman with MS. Methods; R is a 48 years-old woman, diagnosed with MS when she was 22. She started to suffer from weakness of her non-dominant left upper extremity about ten years after the diagnosis. She was referred to the tele-rehabilitation service by her rehabilitation team, 16 years after diagnosis. Her goals were to improve ability to use her affected upper extremity in daily activities. On admission her score in the Mini-Mental State Exam was 30/30. Her Fugl-Meyer Assessment (FMA) score of the left upper extremity was 48/60, indicating mild weakness and she had a limitation of her shoulder abduction (90 degrees). In addition, she reported little use of her arm in daily activities as shown in her responses to the Motor Activity Log (MAL) that were equal to 1.25/5 in amount and 1.37 in quality of use. R. received two 30 minutes on-line sessions per week in the tele-rehabilitation service, with the CogniMotion system. These were complemented by self-practice with the system. The CogniMotion system provides a hybrid (synchronous-asynchronous), the home-based tele-rehabilitation program to improve the motor, cognitive and functional status of people with neurological deficits. The system consists of a computer, large monitor, and the Microsoft’s Kinect 3D sensor. This equipment is located in the client’s home and connected to a clinician’s computer setup in a remote clinic via WiFi. The client sits in front of the monitor and uses his body movements to interact with games and tasks presented on the monitor. The system provides feedback in the form of ‘knowledge of results’ (e.g., the success of a game) and ‘knowledge of performance’ (e.g., alerts for compensatory movements) to enhance motor learning. The games and tasks were adapted for R. motor abilities and level of difficulty was gradually increased according to her abilities. The results of her second assessment (after 35 on-line sessions) showed improvement in her FMA score to 52 and shoulder abduction to 140 degrees. Moreover, her responses to the MAL indicated an increased amount (2.4) and quality (2.2) of use of her left upper extremity in daily activities. She reported high level of enjoyment from the treatments (5/5), specifically the combination of cognitive challenges while moving her body. In addition, she found the system easy to use as reflected by her responses to the System Usability Scale (85/100). To-date, R. continues to receive treatments in the tele-rehabilitation service. To conclude, this case report shows the potential of using tele-rehabilitation for people with MS to provide strategies to enhance the use of the upper extremity in daily activities as well as for maintaining motor function. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=motor%20function" title="motor function">motor function</a>, <a href="https://publications.waset.org/abstracts/search?q=multiple-sclerosis" title=" multiple-sclerosis"> multiple-sclerosis</a>, <a href="https://publications.waset.org/abstracts/search?q=tele-rehabilitation" title=" tele-rehabilitation"> tele-rehabilitation</a>, <a href="https://publications.waset.org/abstracts/search?q=daily%20activities" title=" daily activities"> daily activities</a> </p> <a href="https://publications.waset.org/abstracts/90537/tele-rehabilitation-for-multiple-sclerosis-a-case-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/90537.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">180</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Account <li><a href="https://waset.org/profile">My Account</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Explore <li><a href="https://waset.org/disciplines">Disciplines</a></li> <li><a href="https://waset.org/conferences">Conferences</a></li> <li><a href="https://waset.org/conference-programs">Conference Program</a></li> <li><a href="https://waset.org/committees">Committees</a></li> <li><a href="https://publications.waset.org">Publications</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Research <li><a href="https://publications.waset.org/abstracts">Abstracts</a></li> <li><a href="https://publications.waset.org">Periodicals</a></li> <li><a href="https://publications.waset.org/archive">Archive</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Open Science <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Philosophy.pdf">Open Science Philosophy</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Award.pdf">Open Science Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Society-Open-Science-and-Open-Innovation.pdf">Open Innovation</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Postdoctoral-Fellowship-Award.pdf">Postdoctoral Fellowship Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Scholarly-Research-Review.pdf">Scholarly Research Review</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Support <li><a href="https://waset.org/page/support">Support</a></li> <li><a href="https://waset.org/profile/messages/create">Contact Us</a></li> <li><a href="https://waset.org/profile/messages/create">Report Abuse</a></li> </ul> </div> </div> </div> </div> </div> <div class="container text-center"> <hr style="margin-top:0;margin-bottom:.3rem;"> <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" class="text-muted small">Creative Commons Attribution 4.0 International License</a> <div id="copy" class="mt-2">© 2024 World Academy of Science, Engineering and Technology</div> </div> </footer> <a href="javascript:" id="return-to-top"><i class="fas fa-arrow-up"></i></a> <div class="modal" id="modal-template"> <div class="modal-dialog"> <div class="modal-content"> <div class="row m-0 mt-1"> <div class="col-md-12"> <button type="button" class="close" data-dismiss="modal" aria-label="Close"><span aria-hidden="true">×</span></button> </div> </div> <div class="modal-body"></div> </div> </div> </div> <script src="https://cdn.waset.org/static/plugins/jquery-3.3.1.min.js"></script> <script src="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/js/bootstrap.bundle.min.js"></script> <script src="https://cdn.waset.org/static/js/site.js?v=150220211556"></script> <script> jQuery(document).ready(function() { /*jQuery.get("https://publications.waset.org/xhr/user-menu", function (response) { jQuery('#mainNavMenu').append(response); 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