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[r]" accesskey="r"><span>أحدث التغييرات</span></a></li><li id="n-wrecentchanges" class="mw-list-item"><a href="/wiki/%D8%AE%D8%A7%D8%B5:%D8%A3%D8%AD%D8%AF%D8%AB_%D8%A7%D9%84%D8%AA%D8%BA%D9%8A%D9%8A%D8%B1%D8%A7%D8%AA_%D8%A7%D9%84%D9%85%D9%88%D8%B5%D9%88%D9%84%D8%A9/%D9%88%D9%8A%D9%83%D9%8A%D8%A8%D9%8A%D8%AF%D9%8A%D8%A7:%D8%B5%D9%81%D8%AD%D8%A7%D8%AA_%D9%85%D9%87%D9%85%D8%A9"><span>أحدث التغييرات الأساسية</span></a></li> </ul> </div> </div> <div id="p-navigation" class="vector-menu mw-portlet mw-portlet-navigation" > <div class="vector-menu-heading"> تصفح </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="n-subjects" class="mw-list-item"><a href="/wiki/%D9%88%D9%8A%D9%83%D9%8A%D8%A8%D9%8A%D8%AF%D9%8A%D8%A7:%D8%AA%D8%B5%D9%81%D8%AD"><span>المواضيع</span></a></li><li id="n-index" class="mw-list-item"><a href="/wiki/%D9%88%D9%8A%D9%83%D9%8A%D8%A8%D9%8A%D8%AF%D9%8A%D8%A7:%D9%81%D9%87%D8%B1%D8%B3_%D8%B3%D8%B1%D9%8A%D8%B9"><span>أبجدي</span></a></li><li id="n-portals" class="mw-list-item"><a href="/wiki/%D8%A8%D9%88%D8%A7%D8%A8%D8%A9:%D8%AA%D8%B5%D9%81%D8%AD"><span>بوابات</span></a></li><li id="n-randompage" class="mw-list-item"><a href="/wiki/%D8%AE%D8%A7%D8%B5:%D8%B9%D8%B4%D9%88%D8%A7%D8%A6%D9%8A" title="حمل صفحة عشوائية [x]" accesskey="x"><span>مقالة عشوائية</span></a></li><li id="n-Kiwix" class="mw-list-item"><a href="/wiki/%D9%88%D9%8A%D9%83%D9%8A%D8%A8%D9%8A%D8%AF%D9%8A%D8%A7:%D9%83%D9%8A%D9%88%D9%8A%D9%83%D8%B3"><span>تصفح من غير إنترنت</span></a></li><li id="n-specialpages" class="mw-list-item"><a href="/wiki/%D8%AE%D8%A7%D8%B5:%D8%B5%D9%81%D8%AD%D8%A7%D8%AA_%D8%AE%D8%A7%D8%B5%D8%A9"><span>الصفحات الخاصة</span></a></li> </ul> </div> </div> <div id="p-contributing" class="vector-menu mw-portlet mw-portlet-contributing" > <div class="vector-menu-heading"> مشاركة </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="n-contact" class="mw-list-item"><a href="/wiki/%D9%88%D9%8A%D9%83%D9%8A%D8%A8%D9%8A%D8%AF%D9%8A%D8%A7:%D8%A7%D8%AA%D8%B5%D9%84_%D8%A8%D9%86%D8%A7"><span>تواصل مع ويكيبيديا</span></a></li><li id="n-help" class="mw-list-item"><a href="/wiki/%D9%85%D8%B3%D8%A7%D8%B9%D8%AF%D8%A9:%D9%85%D8%AD%D8%AA%D9%88%D9%8A%D8%A7%D8%AA" title="حيث تجد المساعدة"><span>مساعدة</span></a></li><li id="n-villagepump" class="mw-list-item"><a href="/wiki/%D9%88%D9%8A%D9%83%D9%8A%D8%A8%D9%8A%D8%AF%D9%8A%D8%A7:%D8%A7%D9%84%D9%85%D9%8A%D8%AF%D8%A7%D9%86"><span>الميدان</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> <a href="/wiki/%D8%A7%D9%84%D8%B5%D9%81%D8%AD%D8%A9_%D8%A7%D9%84%D8%B1%D8%A6%D9%8A%D8%B3%D8%A9" class="mw-logo"> <img class="mw-logo-icon" src="/static/images/icons/wikipedia.png" alt="" aria-hidden="true" height="50" width="50"> <span class="mw-logo-container skin-invert"> <img class="mw-logo-wordmark" alt="ويكيبيديا" src="/static/images/mobile/copyright/wikipedia-wordmark-ar.svg" style="width: 7em; height: 2.4375em;"> <img class="mw-logo-tagline" alt="" src="/static/images/mobile/copyright/wikipedia-tagline-ar.svg" width="105" height="22" style="width: 6.5625em; height: 1.375em;"> </span> </a> </div> <div class="vector-header-end"> <div id="p-search" role="search" class="vector-search-box-vue vector-search-box-collapses vector-search-box-show-thumbnail vector-search-box-auto-expand-width vector-search-box"> <a href="/wiki/%D8%AE%D8%A7%D8%B5:%D8%A8%D8%AD%D8%AB" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only search-toggle" title="ابحث في ويكيبيديا [f]" accesskey="f"><span class="vector-icon mw-ui-icon-search mw-ui-icon-wikimedia-search"></span> <span>بحث</span> </a> <div class="vector-typeahead-search-container"> <div class="cdx-typeahead-search cdx-typeahead-search--show-thumbnail cdx-typeahead-search--auto-expand-width"> <form action="/w/index.php" id="searchform" class="cdx-search-input cdx-search-input--has-end-button"> <div id="simpleSearch" class="cdx-search-input__input-wrapper" data-search-loc="header-moved"> <div class="cdx-text-input cdx-text-input--has-start-icon"> <input class="cdx-text-input__input" type="search" name="search" placeholder="ابحث في ويكيبيديا" aria-label="ابحث في ويكيبيديا" autocapitalize="sentences" title="ابحث في ويكيبيديا [f]" accesskey="f" id="searchInput" > <span class="cdx-text-input__icon cdx-text-input__start-icon"></span> </div> <input type="hidden" name="title" value="خاص:بحث"> </div> <button class="cdx-button cdx-search-input__end-button">بحث</button> </form> </div> </div> </div> <nav class="vector-user-links vector-user-links-wide" aria-label="أدوات شخصية"> <div class="vector-user-links-main"> <div id="p-vector-user-menu-preferences" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <div id="p-vector-user-menu-userpage" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <nav class="vector-appearance-landmark" aria-label="المظهر"> <div id="vector-appearance-dropdown" class="vector-dropdown " title="تغيير مظهر الصفحة، حجم الخط، العرض واللون" > <input type="checkbox" id="vector-appearance-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-appearance-dropdown" class="vector-dropdown-checkbox " aria-label="المظهر" > <label id="vector-appearance-dropdown-label" for="vector-appearance-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-appearance mw-ui-icon-wikimedia-appearance"></span> <span class="vector-dropdown-label-text">المظهر</span> </label> <div class="vector-dropdown-content"> <div id="vector-appearance-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <div id="p-vector-user-menu-notifications" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <div id="p-vector-user-menu-overflow" class="vector-menu mw-portlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-sitesupport-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="https://donate.wikimedia.org/?wmf_source=donate&wmf_medium=sidebar&wmf_campaign=ar.wikipedia.org&uselang=ar" class=""><span>تبرع</span></a> </li> <li id="pt-createaccount-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=%D8%AE%D8%A7%D8%B5:%D8%A5%D9%86%D8%B4%D8%A7%D8%A1_%D8%AD%D8%B3%D8%A7%D8%A8&returnto=NUPR1" title="نشجعك على عمل حساب وتسجيل دخولك؛ لكنه غير ضروري على اي حال" class=""><span>إنشاء حساب</span></a> </li> <li id="pt-login-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=%D8%AE%D8%A7%D8%B5:%D8%AF%D8%AE%D9%88%D9%84_%D8%A7%D9%84%D9%85%D8%B3%D8%AA%D8%AE%D8%AF%D9%85&returnto=NUPR1" title="يفضل أن تسجل الدخول، لكنه ليس إلزاميا. [o]" accesskey="o" class=""><span>دخول</span></a> </li> </ul> </div> </div> </div> <div id="vector-user-links-dropdown" class="vector-dropdown vector-user-menu vector-button-flush-right vector-user-menu-logged-out" title="المزيد من الخيارات" > <input type="checkbox" id="vector-user-links-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-user-links-dropdown" class="vector-dropdown-checkbox " aria-label="أدوات شخصية" > <label id="vector-user-links-dropdown-label" for="vector-user-links-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-ellipsis mw-ui-icon-wikimedia-ellipsis"></span> <span class="vector-dropdown-label-text">أدوات شخصية</span> </label> <div class="vector-dropdown-content"> <div id="p-personal" class="vector-menu mw-portlet mw-portlet-personal user-links-collapsible-item" title="قائمة المستخدم" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-sitesupport" class="user-links-collapsible-item mw-list-item"><a href="https://donate.wikimedia.org/?wmf_source=donate&wmf_medium=sidebar&wmf_campaign=ar.wikipedia.org&uselang=ar"><span>تبرع</span></a></li><li id="pt-createaccount" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=%D8%AE%D8%A7%D8%B5:%D8%A5%D9%86%D8%B4%D8%A7%D8%A1_%D8%AD%D8%B3%D8%A7%D8%A8&returnto=NUPR1" title="نشجعك على عمل حساب وتسجيل دخولك؛ لكنه غير ضروري على اي حال"><span class="vector-icon mw-ui-icon-userAdd mw-ui-icon-wikimedia-userAdd"></span> <span>إنشاء حساب</span></a></li><li id="pt-login" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=%D8%AE%D8%A7%D8%B5:%D8%AF%D8%AE%D9%88%D9%84_%D8%A7%D9%84%D9%85%D8%B3%D8%AA%D8%AE%D8%AF%D9%85&returnto=NUPR1" title="يفضل أن تسجل الدخول، لكنه ليس إلزاميا. [o]" accesskey="o"><span class="vector-icon mw-ui-icon-logIn mw-ui-icon-wikimedia-logIn"></span> <span>دخول</span></a></li> </ul> </div> </div> <div id="p-user-menu-anon-editor" class="vector-menu mw-portlet mw-portlet-user-menu-anon-editor" > <div class="vector-menu-heading"> صفحات للمحررين الذين سجَّلوا خروجهم <a href="/wiki/%D9%85%D8%B3%D8%A7%D8%B9%D8%AF%D8%A9:%D9%85%D9%82%D8%AF%D9%85%D8%A9" aria-label="تعلَّم المزيد بخصوص التحرير"><span>تعلَّم المزيد</span></a> </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-anoncontribs" class="mw-list-item"><a href="/wiki/%D8%AE%D8%A7%D8%B5:%D9%85%D8%B3%D8%A7%D9%87%D9%85%D8%A7%D8%AA%D9%8A" title="قائمة بتعديلات قام بها عنوان الآي بي [y]" accesskey="y"><span>مساهمات</span></a></li><li id="pt-anontalk" class="mw-list-item"><a href="/wiki/%D8%AE%D8%A7%D8%B5:%D9%86%D9%82%D8%A7%D8%B4%D9%8A" title="نقاش حول التعديلات من عنوان الأيبي هذا [n]" accesskey="n"><span>نقاش</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> </header> </div> <div class="mw-page-container"> <div class="mw-page-container-inner"> <div class="vector-sitenotice-container"> <div id="siteNotice"></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="الموقع"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="المحتويات" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">المحتويات</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">انقل للشريط الجانبي</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">أخف</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">المقدمة</div> </a> </li> <li id="toc-الوظيفة" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#الوظيفة"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>الوظيفة</span> </div> </a> <ul id="toc-الوظيفة-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-الأهمية_السريرية" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#الأهمية_السريرية"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>الأهمية السريرية</span> </div> </a> <ul id="toc-الأهمية_السريرية-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-المراجع" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#المراجع"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>المراجع</span> </div> </a> <ul id="toc-المراجع-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-قراءة_متعمقة" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#قراءة_متعمقة"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>قراءة متعمقة</span> </div> </a> <ul id="toc-قراءة_متعمقة-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="المحتويات" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" title="جدول المحتويات" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="تبديل عرض جدول المحتويات" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">تبديل عرض جدول المحتويات</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">NUPR1</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="اذهب إلى المقالة في لغةٍ أخرى. مُتاحة في 6 لغات" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-6" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">6 لغات</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-arz mw-list-item"><a href="https://arz.wikipedia.org/wiki/NUPR1" title="NUPR1 – Egyptian Arabic" lang="arz" hreflang="arz" data-title="NUPR1" data-language-autonym="مصرى" data-language-local-name="Egyptian Arabic" class="interlanguage-link-target"><span>مصرى</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/NUPR1" title="NUPR1 – البوسنية" lang="bs" hreflang="bs" data-title="NUPR1" data-language-autonym="Bosanski" data-language-local-name="البوسنية" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/NUPR1" title="NUPR1 – الإنجليزية" lang="en" hreflang="en" data-title="NUPR1" data-language-autonym="English" data-language-local-name="الإنجليزية" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/NUPR1" title="NUPR1 – الإسبانية" lang="es" hreflang="es" data-title="NUPR1" data-language-autonym="Español" data-language-local-name="الإسبانية" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-tt mw-list-item"><a href="https://tt.wikipedia.org/wiki/NUPR1" title="NUPR1 – التترية" lang="tt" hreflang="tt" data-title="NUPR1" data-language-autonym="Татарча / tatarça" data-language-local-name="التترية" class="interlanguage-link-target"><span>Татарча / tatarça</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/NUPR1" title="NUPR1 – الأوكرانية" lang="uk" hreflang="uk" data-title="NUPR1" data-language-autonym="Українська" data-language-local-name="الأوكرانية" class="interlanguage-link-target"><span>Українська</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q18038245#sitelinks-wikipedia" title="تعديل وصلات اللغات" class="wbc-editpage">عدل الوصلات</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="نطاقات"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/NUPR1" title="اعرض صفحة المحتوى [c]" accesskey="c"><span>مقالة</span></a></li><li id="ca-talk" class="vector-tab-noicon mw-list-item"><a href="/wiki/%D9%86%D9%82%D8%A7%D8%B4:NUPR1" rel="discussion" title="نقاش صفحة المحتوى [t]" accesskey="t"><span>نقاش</span></a></li> </ul> </div> </div> <div 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class="infobox" style="width:26.4em"> <tbody><tr><th colspan="4" style="text-align:center;font-size:125%;font-weight:bold">NUPR1 </th></tr><tr><td colspan="4" style="text-align:center"></td> </tr><tr><th colspan="4" style="text-align:center;background-color:#ffcfd2">معرفات </th></tr><tr><th scope="row" style="background-color:#fbf8cc"><span class="plainlinks"><a class="external text" href="https://ar.wikipedia.org/wiki/منظمة_جينوم_الإنسان">أسماء بديلة</a></span> </th><td colspan="3" style="background:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=29990">NUPR1</a>, </span> COM1, P8, nuclear protein 1, transcriptional regulator</td> </tr><tr><th scope="row" style="background-color:#fbf8cc">معرفات خارجية</th> <td colspan="3" style="background-color:#eee"><span class="plainlinks"><a href="/wiki/%D8%A7%D9%84%D9%88%D8%B1%D8%A7%D8%AB%D8%A9_%D8%A7%D9%84%D9%85%D9%86%D8%AF%D9%84%D9%8A%D8%A9_%D8%A7%D9%84%D8%A8%D8%B4%D8%B1%D9%8A%D8%A9_%D8%B9%D8%A8%D8%B1_%D8%A7%D9%84%D8%A5%D9%86%D8%AA%D8%B1%D9%86%D8%AA" title="الوراثة المندلية البشرية عبر الإنترنت">الوراثة المندلية البشرية عبر الإنترنت</a> <a rel="nofollow" class="external text" href="https://omim.org/entry/614812">614812</a> <a href="/wiki/Mouse_Genome_Informatics" class="mw-redirect" title="Mouse Genome Informatics">MGI:</a> <a rel="nofollow" class="external text" href="http://www.informatics.jax.org/marker/MGI:MGI:1891834">MGI:1891834</a> <a href="/wiki/HomoloGene" class="mw-redirect" title="HomoloGene">HomoloGene:</a> <a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=homologene&dopt=HomoloGene&list_uids=8229">8229</a> <a href="/wiki/GeneCards" class="mw-redirect" title="GeneCards">GeneCards:</a> <a rel="nofollow" class="external text" href="http://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=26471">26471</a> </span> </td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"> <table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:right"> <tbody><tr><th colspan="4" style="text-align:center;background-color:#ffcfd2"><a href="/wiki/%D8%B9%D9%84%D9%85_%D8%A7%D9%84%D9%88%D8%AC%D9%88%D8%AF_%D8%A7%D9%84%D8%AC%D9%8A%D9%86%D9%8A" title="علم الوجود الجيني">علم الوجود الجيني</a></th> </tr><tr><th style="background-color:#fbf8cc">وظائف جزيئية</th><td style="background-color:#eee"> <p><span class="plainlinks"><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0003682">chromatin binding</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0003677">ربط دي إن إي</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005515،">‏GO:0001948، ‏GO:0016582 ربط بروتيني</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0003713،">‏GO:0001105 transcription coactivator activity</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0010698">acetyltransferase activator activity</a><br /></span> </p> </td></tr><tr><th style="background-color:#fbf8cc">مكونات خلوية</th><td style="background-color:#eee"> <p><span class="plainlinks"><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005634">نواة</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005829">عصارة خلوية</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0032993">protein-DNA complex</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005737">سيتوبلازم</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0048471">perinuclear region of cytoplasm</a><br /></span> </p> </td></tr><tr><th style="background-color:#fbf8cc">عمليات حيوية</th><td style="background-color:#eee"> <p><span class="plainlinks"><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0035914">skeletal muscle cell differentiation</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0042771">intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0045786">negative regulation of cell cycle</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0008584">male gonad development</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0006355،">‏GO:0009373 ضبط نسخ الدنا</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0002526">acute inflammatory response</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0048147">negative regulation of fibroblast proliferation</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:2000194">regulation of female gonad development</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0009636">response to toxic substance</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0006351">نسخ الدنا</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0006473">protein acetylation</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0031401">positive regulation of protein modification process</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0043065">positive regulation of apoptotic process</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0006357،">‏GO:0044324، ‏GO:0003256، ‏GO:1901213، ‏GO:0046019، ‏GO:0046020، ‏GO:1900094، ‏GO:0061216، ‏GO:0060994، ‏GO:1902064، ‏GO:0003258، ‏GO:0072212 ضبط النسخ انطلاقاً من محفز بوليميراز الرنا الثاني</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0008283">تكاثر خلوي</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0065003،">‏GO:0034622 protein-containing complex assembly</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0008285">negative regulation of cell population proliferation</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0043085،">‏GO:0048554 positive regulation of catalytic activity</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1901800">positive regulation of proteasomal protein catabolic process</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1903508">positive regulation of nucleic acid-templated transcription</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0010506">regulation of autophagy</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0010507">negative regulation of autophagy</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0010667">negative regulation of cardiac muscle cell apoptotic process</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0043066">negative regulation of apoptotic process</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0043433">negative regulation of DNA-binding transcription factor activity</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0043525">positive regulation of neuron apoptotic process</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0045820">negative regulation of glycolytic process</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0050680">negative regulation of epithelial cell proliferation</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0062099">negative regulation of programmed necrotic cell death</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0150078">positive regulation of neuroinflammatory response</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1902902">negative regulation of autophagosome assembly</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1903862">positive regulation of oxidative phosphorylation</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1904036">negative regulation of epithelial cell apoptotic process</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1904691">negative regulation of type B pancreatic cell proliferation</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1905897">regulation of response to endoplasmic reticulum stress</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:2001244">positive regulation of intrinsic apoptotic signaling pathway</a><br /></span> </p> </td></tr><tr><td colspan="4" style="background-color:#eee;text-align:center">المصادر:<a rel="nofollow" class="external text" href="http://amigo.geneontology.org/">Amigo</a> / <a rel="nofollow" class="external text" href="http://www.ebi.ac.uk/QuickGO/">QuickGO</a></td></tr></tbody></table></td></tr><tr><th colspan="4" style="text-align:center;background-color:#ffcfd2">نمط التعبير عن الحمض النووي الريبوزي</th> </tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span class="mw-default-size" typeof="mw:File/Frameless"><a href="/wiki/%D9%85%D9%84%D9%81:PBB_GE_NUPR1_209230_s_at_fs.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b6/PBB_GE_NUPR1_209230_s_at_fs.png/220px-PBB_GE_NUPR1_209230_s_at_fs.png" decoding="async" width="220" height="159" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b6/PBB_GE_NUPR1_209230_s_at_fs.png/330px-PBB_GE_NUPR1_209230_s_at_fs.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b6/PBB_GE_NUPR1_209230_s_at_fs.png/440px-PBB_GE_NUPR1_209230_s_at_fs.png 2x" data-file-width="732" data-file-height="530" /></a></span></td> </tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="http://biogps.org/gene/26471/">المزيد من بيانات التعبير المرجعية</a></span> </td></tr><tr><th colspan="4" style="text-align:center;background-color:#ffcfd2">تماثلات متسلسلة</th> </tr><tr><th scope="row" style="background-color:#fbf8cc">أنواع</th> <td><b>الإنسان</b></td> <td><b>الفأر</b></td> </tr><tr><th scope="row" style="background-color:#fbf8cc"><a href="/wiki/%D8%A3%D9%86%D8%AA%D8%B1%D9%8A%D9%87" title="أنتريه">أنتريه</a></th> <td><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=26471&rn=1">26471</a></span> </td><td><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=56312&rn=1">56312</a></span> </td></tr><tr><th scope="row" style="background-color:#fbf8cc"><a href="/wiki/Ensembl" class="mw-redirect" title="Ensembl">Ensembl</a></th> <td><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Homo_sapiens/geneview?gene=ENSG00000176046;db=core">ENSG00000176046</a></span> </td><td><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Mus_musculus/geneview?gene=ENSMUSG00000030717;db=core">ENSMUSG00000030717</a></span> </td></tr><tr><th scope="row" style="background-color:#fbf8cc"><a href="/wiki/%D9%8A%D9%88%D9%86%D9%8A%D8%A8%D8%B1%D9%88%D8%AA" title="يونيبروت">يونيبروت</a></th> <td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr> <th colspan="1"><span class="plainlinks"></span></th> </tr><tr><td colspan="1"> <p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.uniprot.org/uniprot/O60356">O60356</a> </p></td></tr></tbody></table> </td><td><table style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr> <th colspan="1"><span class="plainlinks"></span></th> </tr><tr><td colspan="1"> <p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.uniprot.org/uniprot/Q9WTK0">Q9WTK0</a> </p></td></tr></tbody></table> </td></tr><tr><th scope="row" style="background-color:#fbf8cc">RefSeq (<a href="/wiki/%D9%85%D8%B1%D8%B3%D8%A7%D9%84_%D8%A7%D9%84%D8%AD%D9%85%D8%B6_%D8%A7%D9%84%D9%86%D9%88%D9%88%D9%8A_%D8%A7%D9%84%D8%B1%D9%8A%D8%A8%D9%88%D8%B2%D9%8A" class="mw-redirect" title="مرسال الحمض النووي الريبوزي">رنا مرسال.</a>)</th> <td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr> <th colspan="1" class="plainlinks"></th> </tr><tr><td colspan="1"> <p><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_012385،">‏NM_001042483 NM_012385، ‏NM_001042483</a></span> </p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr> <th colspan="1" class="plainlinks"></th> </tr><tr><td colspan="1"> <p><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_019738">NM_019738</a></span> </p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#fbf8cc"><a href="/wiki/RefSeq" class="mw-redirect" title="RefSeq">RefSeq</a> (بروتين)</th> <td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr> <th colspan="1" class="plainlinks"></th> </tr><tr><td colspan="1"> <p><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001035948،">‏NP_036517 NP_001035948، ‏NP_036517</a></span> </p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr> <th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"> <p><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_062712">NP_062712</a></span> </p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#fbf8cc">الموقع (<a href="/wiki/%D9%82%D8%A7%D8%B9%D8%AF%D8%A9_%D8%A8%D9%8A%D8%A7%D9%86%D8%A7%D8%AA_%D8%AC%D8%A7%D9%85%D8%B9%D8%A9_%D9%83%D8%A7%D9%84%D9%8A%D9%81%D9%88%D8%B1%D9%86%D9%8A%D8%A7_(%D8%B3%D8%A7%D9%86%D8%AA%D8%A7_%D9%83%D8%B1%D9%88%D8%B2)" class="mw-redirect" title="قاعدة بيانات جامعة كاليفورنيا (سانتا كروز)">UCSC</a></th> <td><span class="plainlinks">n/a</span> </td><td><span class="plainlinks"><a rel="nofollow" class="external text" href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=Human&db=mm0&position=chr7:126222421-126230033">Chr 7: 126.22 – 126.23 Mb</a></span> </td></tr><tr><th scope="row" style="background-color:#fbf8cc">بحث <a href="/wiki/%D8%A8%D8%A8%D9%85%D8%AF" title="ببمد">ببمد</a></th> <td><span class="plainlinks"><a rel="nofollow" class="external autonumber" href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=26471">[1]</a></span> </td><td><span class="plainlinks"><a rel="nofollow" class="external autonumber" href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=56312">[2]</a></span> </td></tr><tr><td colspan="4" style="text-align:center;font-size:x-small;background-color:#eee"><a href="/wiki/%D9%88%D9%8A%D9%83%D9%8A_%D8%A8%D9%8A%D8%A7%D9%86%D8%A7%D8%AA" title="ويكي بيانات">ويكي بيانات</a></td></tr><tr><td colspan="4" style="text-align:center;font-size:x-small;background-color:#eee"><table style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="2" style="background-color:#eee;text-align:center;font-size:x-small"><a href="https://www.wikidata.org/wiki/Q18038245" class="extiw" title="d:Q18038245">اعرض/عدّل إنسان</a></td><td colspan="2" style="background-color:#eee;text-align:center;font-size:x-small"><a href="https://www.wikidata.org/wiki/Q18258368" class="extiw" title="d:Q18258368">اعرض/عدّل فأر</a></td></tr></tbody></table></td></tr></tbody></table> <p><b>NUPR1</b>‏ (<b>Nuclear protein 1, transcriptional regulator</b>) هوَ <a href="/wiki/%D8%A8%D8%B1%D9%88%D8%AA%D9%8A%D9%86" title="بروتين">بروتين</a> <a href="/wiki/%D9%85%D9%86%D8%B7%D9%82%D8%A9_%D9%85%D8%B4%D9%81%D8%B1%D8%A9" title="منطقة مشفرة">يُشَفر</a> بواسطة <a href="/wiki/%D8%AC%D9%8A%D9%86" title="جين">جين</a> NUPR1 في <a href="/wiki/%D8%A5%D9%86%D8%B3%D8%A7%D9%86" title="إنسان">الإنسان</a>.<sup id="cite_ref-pmid10092851_1-0" class="reference"><a href="#cite_note-pmid10092851-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-entrez_2-0" class="reference"><a href="#cite_note-entrez-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid10493524_3-0" class="reference"><a href="#cite_note-pmid10493524-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid9405444_4-0" class="reference"><a href="#cite_note-pmid9405444-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="الوظيفة"><span id=".D8.A7.D9.84.D9.88.D8.B8.D9.8A.D9.81.D8.A9"></span>الوظيفة</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=NUPR1&action=edit&section=1" title="عدل القسم: الوظيفة"><span>عدل</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r68107301">.mw-parser-output .ambox{margin:0;border:1px solid #a2a9b1;border-right:2px solid #36c;background-color:var(--background-color-neutral-subtle,#f8f9fa);box-sizing:border-box}.mw-parser-output .ambox+link+.ambox,.mw-parser-output .ambox+link+style+.ambox,.mw-parser-output .ambox+link+link+.ambox,.mw-parser-output .ambox+.mw-empty-elt+link+.ambox,.mw-parser-output .ambox+.mw-empty-elt+link+style+.ambox,.mw-parser-output .ambox+.mw-empty-elt+link+link+.ambox{margin-top:-1px}html body.mediawiki .mw-parser-output .ambox.mbox-small-right{margin:4px 1em 4px 0;overflow:hidden;width:238px;border-collapse:collapse;font-size:88%;line-height:1.25em}.mw-parser-output .ambox-speedy{border:1px solid #b32424;border-right:2px solid #b32424;background-color:var(--background-color-neutral-subtle,#fee7e6)}.mw-parser-output .ambox-delete{border:1px solid #b32424;border-right:2px solid #b32424}.mw-parser-output .ambox-content{border:1px solid #f28500;border-right:2px solid #f28500}.mw-parser-output .ambox-style{border:1px solid #fc3;border-right:2px solid #fc3}.mw-parser-output .ambox-move{border:1px solid #9932cc;border-right:2px solid #9932cc}.mw-parser-output .ambox-current{border:1px solid #A5D6A7;border-right:2px solid #A5D6A7}.mw-parser-output .ambox-featured{border:1px solid #C0C0C0}.mw-parser-output .ambox-protection{border-right:1px solid #a2a9b1;border-right:2px solid #a2a9b1}.mw-parser-output .ambox .mbox-text{border:none;padding:0.25em 0.5em;width:100%;font-size:95%}.mw-parser-output .ambox .mbox-text .date-container{font-size:smaller}.mw-parser-output .ambox .mbox-image{border:none;padding:2px 0.9em 2px 0;text-align:center}.mw-parser-output .ambox .mbox-imageleft{border:none;padding:2px 0 2px 0.9em;text-align:center}.mw-parser-output .ambox .mbox-empty-cell{border:none;padding:0;width:1px}.mw-parser-output .ambox .mbox-image-div{width:42px}html.client-js body.skin-minerva .mw-parser-output .mbox-text-span{margin-right:23px!important}@media(min-width:720px){.mw-parser-output .ambox{margin:0}}.mw-parser-output .ambox th.mbox-text,.mw-parser-output .ambox td.mbox-text{padding:0.25em 0.5em;font-size:95%}.mw-parser-output .ambox th.mbox-text .date-container,.mw-parser-output .ambox td.mbox-text .date-container{font-size:small}.mw-parser-output .ambox td.mbox-image{padding:2px 0.2em 2px 0}.mw-parser-output .ambox td.mbox-imageleft{padding:2px 0.2em 2px 0}.mw-parser-output .ambox-notice{border:1px solid #36c;border-right:2px solid #36c}.mw-parser-output .compact-ambox table .mbox-image,.mw-parser-output .compact-ambox table .mbox-imageleft,.mw-parser-output .compact-ambox table .mbox-empty-cell{display:none}.mw-parser-output .compact-ambox table.ambox{border:none;border-collapse:collapse;background-color:transparent;margin:0 1.6em 0 0!important;padding:0!important;width:auto;display:block}body.mediawiki .mw-parser-output .compact-ambox table.mbox-small-right{font-size:100%;width:auto;margin:0}.mw-parser-output .compact-ambox table .mbox-text{padding:0!important;margin:0!important}.mw-parser-output .compact-ambox table .mbox-text-span{display:list-item;line-height:1.5em;list-style-type:square}.mw-parser-output .compact-ambox .hide-when-compact{display:none}.mw-parser-output .compact-ambox .hide-when-compact{display:none}</style><table class="box-قسم_فارغ plainlinks metadata ambox mbox-small-right ambox-content" role="presentation" style="width:auto;"><tbody><tr><td class="mbox-image"><span typeof="mw:File"><a href="/wiki/%D9%85%D9%84%D9%81:Crystal_xedit.svg" class="mw-file-description"><img alt="[أيقونة]" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/dd/Crystal_xedit.svg/20px-Crystal_xedit.svg.png" decoding="async" width="20" height="15" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/dd/Crystal_xedit.svg/30px-Crystal_xedit.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/dd/Crystal_xedit.svg/40px-Crystal_xedit.svg.png 2x" data-file-width="800" data-file-height="600" /></a></span></td><td class="mbox-text" style="width:auto;"><div class="mbox-text-span"><b>هذا القسم فارغ أو غير مكتمل.</b> ساهم <a class="external text" href="https://ar.wikipedia.org/w/index.php?title=NUPR1&action=edit&section=">في توسيعه</a>. <span class="date-container"><i>(<span class="date">يوليو 2018</span>)</i></span></div></td></tr></tbody></table> <div class="mw-heading mw-heading2"><h2 id="الأهمية_السريرية"><span id=".D8.A7.D9.84.D8.A3.D9.87.D9.85.D9.8A.D8.A9_.D8.A7.D9.84.D8.B3.D8.B1.D9.8A.D8.B1.D9.8A.D8.A9"></span>الأهمية السريرية</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=NUPR1&action=edit&section=2" title="عدل القسم: الأهمية السريرية"><span>عدل</span></a><span class="mw-editsection-bracket">]</span></span></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r68107301" /><table class="box-قسم_فارغ plainlinks metadata ambox mbox-small-right ambox-content" role="presentation" style="width:auto;"><tbody><tr><td class="mbox-image"><span typeof="mw:File"><a href="/wiki/%D9%85%D9%84%D9%81:Crystal_xedit.svg" class="mw-file-description"><img alt="[أيقونة]" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/dd/Crystal_xedit.svg/20px-Crystal_xedit.svg.png" decoding="async" width="20" height="15" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/dd/Crystal_xedit.svg/30px-Crystal_xedit.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/dd/Crystal_xedit.svg/40px-Crystal_xedit.svg.png 2x" data-file-width="800" data-file-height="600" /></a></span></td><td class="mbox-text" style="width:auto;"><div class="mbox-text-span"><b>هذا القسم فارغ أو غير مكتمل.</b> ساهم <a class="external text" href="https://ar.wikipedia.org/w/index.php?title=NUPR1&action=edit&section=">في توسيعه</a>. <span class="date-container"><i>(<span class="date">يوليو 2018</span>)</i></span></div></td></tr></tbody></table> <div class="mw-heading mw-heading2"><h2 id="المراجع"><span id=".D8.A7.D9.84.D9.85.D8.B1.D8.A7.D8.AC.D8.B9"></span>المراجع</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=NUPR1&action=edit&section=3" title="عدل القسم: المراجع"><span>عدل</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r68964954">.mw-parser-output .reflist-wrap{overflow-y:auto;max-height:300px}.mw-parser-output .reflist{font-size:90%;margin-bottom:0.5em;list-style-type:decimal}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:36em}.mw-parser-output .reflist-columns-3{column-width:28em}.mw-parser-output .reflist-columns-4{column-width:20em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}@media print{.mw-parser-output .reflist{overflow-y:visible!important;max-height:none!important}}</style><div class="reflist-wrap"><div class="reflist mw-content-ltr" dir="ltr"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-pmid10092851-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid10092851_1-0">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r68982381">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")left 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free 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Biol</i>. ج. 27 ع. 4: 1348–55. <a href="/wiki/%D9%85%D8%B9%D8%B1%D9%81_%D8%A7%D9%84%D8%BA%D8%B1%D8%B6_%D8%A7%D9%84%D8%B1%D9%82%D9%85%D9%8A" title="معرف الغرض الرقمي">DOI</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1128%2FMCB.00658-06">10.1128/MCB.00658-06</a>. <a href="/wiki/%D8%A8%D8%A8%D9%85%D8%AF_%D8%B3%D9%86%D8%AA%D8%B1%D8%A7%D9%84" title="ببمد سنترال">PMC</a>:<span class="id-lock-free" title="يمكن الوصول إليها بحرية"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800732">1800732</a></span>. <a href="/wiki/%D8%A8%D8%A8%D9%85%D8%AF" title="ببمد">PMID</a>:<a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/17101797">17101797</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Mol.+Cell.+Biol.&rft.atitle=The+SYT-SSX+fusion+protein+down-regulates+the+cell+proliferation+regulator+COM1+in+t%28x%3B18%29+synovial+sarcoma.&rft.volume=27&rft.issue=4&rft.pages=1348-55&rft.date=2007&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1800732%23id-name%3DPMC&rft_id=info%3Apmid%2F17101797&rft_id=info%3Adoi%2F10.1128%2FMCB.00658-06&rft.aulast=Ishida&rft.aufirst=M&rft.au=Miyamoto%2C+M&rft.au=Naitoh%2C+S&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fsim_molecular-and-cellular-biology_2007-02_27_4%2Fpage%2F1348&rfr_id=info%3Asid%2Far.wikipedia.org%3ANUPR1" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r68982381" /><cite id="CITEREFGoruppiPattenForceKyriakis2007" class="citation journal cs1">Goruppi S، Patten RD، Force T، Kyriakis JM (2007). <a rel="nofollow" class="external text" href="https://archive.org/details/sim_molecular-and-cellular-biology_2007-02_27_3/page/993">"Helix-loop-helix protein p8, a transcriptional regulator required for cardiomyocyte hypertrophy and cardiac fibroblast matrix metalloprotease induction"</a>. <i>Mol. Cell. Biol</i>. ج. 27 ع. 3: 993–1006. <a href="/wiki/%D9%85%D8%B9%D8%B1%D9%81_%D8%A7%D9%84%D8%BA%D8%B1%D8%B6_%D8%A7%D9%84%D8%B1%D9%82%D9%85%D9%8A" title="معرف الغرض الرقمي">DOI</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1128%2FMCB.00996-06">10.1128/MCB.00996-06</a>. <a href="/wiki/%D8%A8%D8%A8%D9%85%D8%AF_%D8%B3%D9%86%D8%AA%D8%B1%D8%A7%D9%84" title="ببمد سنترال">PMC</a>:<span class="id-lock-free" title="يمكن الوصول إليها بحرية"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800682">1800682</a></span>. <a href="/wiki/%D8%A8%D8%A8%D9%85%D8%AF" title="ببمد">PMID</a>:<a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/17116693">17116693</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Mol.+Cell.+Biol.&rft.atitle=Helix-loop-helix+protein+p8%2C+a+transcriptional+regulator+required+for+cardiomyocyte+hypertrophy+and+cardiac+fibroblast+matrix+metalloprotease+induction.&rft.volume=27&rft.issue=3&rft.pages=993-1006&rft.date=2007&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1800682%23id-name%3DPMC&rft_id=info%3Apmid%2F17116693&rft_id=info%3Adoi%2F10.1128%2FMCB.00996-06&rft.aulast=Goruppi&rft.aufirst=S&rft.au=Patten%2C+RD&rft.au=Force%2C+T&rft.au=Kyriakis%2C+JM&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fsim_molecular-and-cellular-biology_2007-02_27_3%2Fpage%2F993&rfr_id=info%3Asid%2Far.wikipedia.org%3ANUPR1" class="Z3988"></span></li></ul> </div> </div> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r64177691">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist 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id="معرفات_مركب_كيميائي_frameless&#124;text-top&#124;10px&#124;alt=عدلها_في_ويكي_بيانات&#124;link=https&#58;//www.wikidata.org/wiki/Q18038245#identifiers&#124;class=noprint&#124;عدلها_في_ويكي_بيانات" scope="row" class="navbox-group" style="width:12%"><a href="/wiki/%D9%85%D8%B1%D9%83%D8%A8_%D9%83%D9%8A%D9%85%D9%8A%D8%A7%D8%A6%D9%8A" title="مركب كيميائي">معرفات مركب كيميائي</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q18038245#identifiers" title="عدلها في ويكي بيانات"><img alt="عدلها في ويكي بيانات" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, 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class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><style data-mw-deduplicate="TemplateStyles:r67666671">.mw-parser-output .navbar{display:inline;font-size:88%;font-weight:normal}.mw-parser-output .navbar-collapse{float:right;text-align:right}.mw-parser-output .navbar-boxtext{word-spacing:0}.mw-parser-output .navbar ul{display:inline-block;white-space:nowrap;line-height:inherit}.mw-parser-output .navbar-brackets::before{margin-left:-0.125em;content:"[ "}.mw-parser-output .navbar-brackets::after{margin-right:-0.125em;content:" ]"}.mw-parser-output .navbar li{word-spacing:-0.125em}.mw-parser-output .navbar a>span,.mw-parser-output .navbar a>abbr{text-decoration:inherit}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 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class="external text" href="https://ar.wikipedia.org/w/index.php?title=%D9%82%D8%A7%D9%84%D8%A8:%D8%AC%D9%8A%D9%86%D8%A7%D8%AA_%D8%A7%D9%84%D9%83%D8%B1%D9%88%D9%85%D9%88%D8%B3%D9%88%D9%85_16&action=edit"><abbr title="عدل هذا القالب">ت</abbr></a></li></ul></div><div id="جينات_الكروموسوم_16" style="font-size:114%;margin:0 4em">جينات الكروموسوم 16</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/w/index.php?title=%D8%AC%D9%8A%D9%86%D8%A7%D8%AA_%D8%A7%D9%84%D9%83%D8%B1%D9%88%D9%85%D9%88%D8%B3%D9%88%D9%85_16&action=edit&redlink=1" class="new" title="جينات الكروموسوم 16 (الصفحة غير موجودة)">جينات الكروموسوم 16</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/RAB26" title="RAB26">RAB26</a></li> <li><a href="/wiki/ARL6IP1" title="ARL6IP1">ARL6IP1</a></li> <li><a href="/wiki/CLDN6" title="CLDN6">CLDN6</a></li> <li><a href="/wiki/PARD6A" title="PARD6A">PARD6A</a></li> <li><a href="/wiki/C16orf62" title="C16orf62">C16orf62</a></li> <li><a href="/wiki/ZNF23" title="ZNF23">ZNF23</a></li> <li><a href="/wiki/MT1X" title="MT1X">MT1X</a></li> <li><a href="/wiki/TSC2" title="TSC2">TSC2</a></li> <li><a href="/wiki/FBXO31" title="FBXO31">FBXO31</a></li> <li><a href="/wiki/KIFC3" title="KIFC3">KIFC3</a></li> <li><a href="/wiki/SRRM2" title="SRRM2">SRRM2</a></li> <li><a href="/wiki/TBX6" title="TBX6">TBX6</a></li> <li><a href="/wiki/MYLPF" title="MYLPF">MYLPF</a></li> <li><a href="/wiki/EXOC3L" title="EXOC3L">EXOC3L</a></li> <li><a href="/wiki/SEPT12" title="SEPT12">SEPT12</a></li> <li><a href="/wiki/ENKD1" title="ENKD1">ENKD1</a></li> <li><a href="/wiki/RSL1D1" title="RSL1D1">RSL1D1</a></li> <li><a href="/wiki/TERF2IP" title="TERF2IP">TERF2IP</a></li> <li><a href="/wiki/CDH15" title="CDH15">CDH15</a></li> <li><a href="/wiki/VAC14" title="VAC14">VAC14</a></li> <li><a href="/wiki/CBFA2T3" title="CBFA2T3">CBFA2T3</a></li> <li><a href="/wiki/ELMO3" title="ELMO3">ELMO3</a></li> <li><a href="/wiki/Periplakin" title="Periplakin">Periplakin</a></li> <li><a href="/wiki/CMTM2" title="CMTM2">CMTM2</a></li> <li><a href="/wiki/MT1B" title="MT1B">MT1B</a></li> <li><a href="/wiki/PRRT2" title="PRRT2">PRRT2</a></li> <li><a href="/wiki/C16orf58" title="C16orf58">C16orf58</a></li> <li><a href="/wiki/UQCRC2" title="UQCRC2">UQCRC2</a></li> <li><a href="/wiki/MKL2" title="MKL2">MKL2</a></li> <li><a href="/wiki/ZFPM1" title="ZFPM1">ZFPM1</a></li> <li><a href="/wiki/CNOT1" title="CNOT1">CNOT1</a></li> <li><a href="/wiki/ABCC12" title="ABCC12">ABCC12</a></li> <li><a href="/wiki/IRX6" title="IRX6">IRX6</a></li> <li><a href="/wiki/MT1E" title="MT1E">MT1E</a></li> <li><a href="/wiki/TNP2" title="TNP2">TNP2</a></li> <li><a href="/wiki/LOC124220" title="LOC124220">LOC124220</a></li> <li><a href="/wiki/SHCBP1" title="SHCBP1">SHCBP1</a></li> <li><a href="/wiki/CCL22" title="CCL22">CCL22</a></li> <li><a href="/wiki/CDH11" title="CDH11">CDH11</a></li> <li><a href="/wiki/ATXN2L" title="ATXN2L">ATXN2L</a></li> <li><a href="/wiki/NPW" title="NPW">NPW</a></li> <li><a href="/wiki/KATNB1" title="KATNB1">KATNB1</a></li> <li><a href="/wiki/WFDC1" title="WFDC1">WFDC1</a></li> <li><a class="mw-selflink selflink">NUPR1</a></li> <li><a href="/wiki/KIAA0182" title="KIAA0182">KIAA0182</a></li> <li><a href="/wiki/PDPR" title="PDPR">PDPR</a></li> <li><a href="/wiki/IGFALS" title="IGFALS">IGFALS</a></li> <li><a href="/wiki/TBC1D24" title="TBC1D24">TBC1D24</a></li> <li><a href="/wiki/CHTF18" title="CHTF18">CHTF18</a></li> <li><a href="/wiki/BAIAP3" title="BAIAP3">BAIAP3</a></li> <li><a href="/wiki/RBFOX1" title="RBFOX1">RBFOX1</a></li> <li><a href="/wiki/BBS2" title="BBS2">BBS2</a></li> <li><a href="/wiki/NFATC2IP" title="NFATC2IP">NFATC2IP</a></li> <li><a href="/wiki/FHOD1" title="FHOD1">FHOD1</a></li> <li><a href="/wiki/DDX19B" title="DDX19B">DDX19B</a></li> <li><a href="/wiki/SLC7A5" title="SLC7A5">SLC7A5</a></li> <li><a href="/wiki/E2F4" title="E2F4">E2F4</a></li> <li><a href="/wiki/ZNF423" title="ZNF423">ZNF423</a></li> <li><a href="/wiki/MLST8" title="MLST8">MLST8</a></li> <li><a href="/wiki/GLG1" title="GLG1">GLG1</a></li> <li><a href="/wiki/METRN" title="METRN">METRN</a></li> <li><a href="/wiki/PRSS8" title="PRSS8">PRSS8</a></li> <li><a href="/wiki/CENPN" title="CENPN">CENPN</a></li> <li><a href="/wiki/XPO6" title="XPO6">XPO6</a></li> <li><a href="/wiki/RPGRIP1L" title="RPGRIP1L">RPGRIP1L</a></li> <li><a href="/wiki/CDH8" title="CDH8">CDH8</a></li> <li><a href="/wiki/ZNF469" title="ZNF469">ZNF469</a></li> <li><a href="/wiki/WFIKKN1" title="WFIKKN1">WFIKKN1</a></li> <li><a href="/wiki/PRKCB1" title="PRKCB1">PRKCB1</a></li> <li><a href="/wiki/TOX3" title="TOX3">TOX3</a></li> <li><a href="/wiki/VPS35" title="VPS35">VPS35</a></li> <li><a href="/wiki/E4F1" title="E4F1">E4F1</a></li> <li><a href="/wiki/IRX3" title="IRX3">IRX3</a></li> <li><a href="/wiki/RBBP6" title="RBBP6">RBBP6</a></li> <li><a href="/wiki/FOXF1" title="FOXF1">FOXF1</a></li> <li><a href="/wiki/EFCBP2" title="EFCBP2">EFCBP2</a></li> <li><a href="/wiki/NDE1" title="NDE1">NDE1</a></li> <li><a href="/wiki/COG7" title="COG7">COG7</a></li> <li><a href="/wiki/GNAO1" title="GNAO1">GNAO1</a></li> <li><a href="/wiki/TRAP1" title="TRAP1">TRAP1</a></li> <li><a href="/wiki/HERPUD1" title="HERPUD1">HERPUD1</a></li> <li><a href="/wiki/ZP2" title="ZP2">ZP2</a></li> <li><a href="/wiki/CDYL2" title="CDYL2">CDYL2</a></li> <li><a href="/wiki/ARHGDIG" title="ARHGDIG">ARHGDIG</a></li> <li><a href="/wiki/ZNF267" title="ZNF267">ZNF267</a></li> <li><a href="/wiki/ABAT" title="ABAT">ABAT</a></li> <li><a href="/wiki/NOB1" title="NOB1">NOB1</a></li> <li><a href="/wiki/COTL1" title="COTL1">COTL1</a></li> <li><a href="/wiki/KIAA0430" title="KIAA0430">KIAA0430</a></li> <li><a href="/wiki/CD2BP2" title="CD2BP2">CD2BP2</a></li> <li><a href="/wiki/TANGO6" title="TANGO6">TANGO6</a></li> <li><a href="/wiki/TBL3" title="TBL3">TBL3</a></li> <li><a href="/wiki/KCTD13" title="KCTD13">KCTD13</a></li> <li><a href="/wiki/RHBDF1" title="RHBDF1">RHBDF1</a></li> <li><a href="/wiki/KIAA0174" title="KIAA0174">KIAA0174</a></li> <li><a href="/wiki/TMEM219" title="TMEM219">TMEM219</a></li> <li><a href="/wiki/PMFBP1" title="PMFBP1">PMFBP1</a></li> <li><a href="/wiki/COQ9" title="COQ9">COQ9</a></li> <li><a href="/wiki/KIF22" title="KIF22">KIF22</a></li> <li><a href="/wiki/EIF3C" title="EIF3C">EIF3C</a></li> <li><a href="/wiki/SEPT1" title="SEPT1">SEPT1</a></li> <li><a href="/wiki/DNAJA2" title="DNAJA2">DNAJA2</a></li> <li><a href="/wiki/GABARAPL2" title="GABARAPL2">GABARAPL2</a></li> <li><a href="/wiki/CIRH1A" title="CIRH1A">CIRH1A</a></li> <li><a href="/wiki/NIP7" title="NIP7">NIP7</a></li> <li><a href="/wiki/FA2H" title="FA2H">FA2H</a></li> <li><a href="/wiki/DOK4" title="DOK4">DOK4</a></li> <li><a href="/wiki/PDIA2" title="PDIA2">PDIA2</a></li> <li><a href="/wiki/CNTNAP4" title="CNTNAP4">CNTNAP4</a></li> <li><a href="/wiki/CLDN9" title="CLDN9">CLDN9</a></li> <li><a href="/wiki/IRX5" title="IRX5">IRX5</a></li> <li><a href="/wiki/RGS11" title="RGS11">RGS11</a></li> <li><a href="/wiki/GNG13" title="GNG13">GNG13</a></li> <li><a href="/wiki/CMTM3" title="CMTM3">CMTM3</a></li> <li><a href="/wiki/ATBF1" title="ATBF1">ATBF1</a></li> <li><a href="/wiki/RAB11FIP3" title="RAB11FIP3">RAB11FIP3</a></li> <li><a href="/wiki/FBRS" title="FBRS">FBRS</a></li> <li><a href="/wiki/HBQ1" title="HBQ1">HBQ1</a></li> <li><a href="/wiki/SOX8" title="SOX8">SOX8</a></li> <li><a href="/wiki/ORC6" title="ORC6">ORC6</a></li> <li><a href="/wiki/SNTB2" title="SNTB2">SNTB2</a></li> <li><a href="/wiki/CRYM" title="CRYM">CRYM</a></li> <li><a href="/wiki/ERAF" title="ERAF">ERAF</a></li> <li><a href="/wiki/TNRC6A" title="TNRC6A">TNRC6A</a></li> <li><a href="/wiki/COG4" title="COG4">COG4</a></li> <li><a href="/wiki/FAM57B" title="FAM57B">FAM57B</a></li> <li><a href="/wiki/GFER" title="GFER">GFER</a></li> <li><a href="/wiki/NIP30" title="NIP30">NIP30</a></li> <li><a href="/wiki/DYNC1LI2" title="DYNC1LI2">DYNC1LI2</a></li> <li><a href="/wiki/WDR24" title="WDR24">WDR24</a></li> <li><a href="/wiki/CFDP1" title="CFDP1">CFDP1</a></li> <li><a href="/wiki/MRPL28" title="MRPL28">MRPL28</a></li> <li><a href="/wiki/GINS2" title="GINS2">GINS2</a></li> <li><a href="/wiki/NME4" title="NME4">NME4</a></li> <li><a href="/wiki/GTF3C1" title="GTF3C1">GTF3C1</a></li> <li><a href="/wiki/LRRC50" title="LRRC50">LRRC50</a></li> <li><a href="/wiki/NDRG4" title="NDRG4">NDRG4</a></li> <li><a href="/wiki/DCTN5" title="DCTN5">DCTN5</a></li> <li><a href="/wiki/DOC2A" title="DOC2A">DOC2A</a></li> <li><a href="/wiki/CTRB2" title="CTRB2">CTRB2</a></li> <li><a href="/wiki/SF3B3" title="SF3B3">SF3B3</a></li> <li><a href="/wiki/CCP110" title="CCP110">CCP110</a></li> <li><a href="/wiki/VAT1L" title="VAT1L">VAT1L</a></li> <li><a href="/wiki/SETD6" title="SETD6">SETD6</a></li> <li><a href="/wiki/GLIS2" title="GLIS2">GLIS2</a></li> <li><a href="/wiki/RRAD" title="RRAD">RRAD</a></li> <li><a href="/wiki/PRR35" title="PRR35">PRR35</a></li> <li><a href="/wiki/MT1F" title="MT1F">MT1F</a></li> <li><a href="/wiki/Metallothionein-3" title="Metallothionein-3">Metallothionein-3</a></li> <li><a href="/wiki/LUC7L" title="LUC7L">LUC7L</a></li> <li><a href="/wiki/CBFB" title="CBFB">CBFB</a></li> <li><a href="/wiki/TELO2" title="TELO2">TELO2</a></li> <li><a href="/wiki/ARMC5" title="ARMC5">ARMC5</a></li> <li><a href="/wiki/VPS4A" title="VPS4A">VPS4A</a></li> <li><a href="/wiki/TUFM" title="TUFM">TUFM</a></li> <li><a href="/wiki/ZNF598" title="ZNF598">ZNF598</a></li> <li><a href="/wiki/STX1B" title="STX1B">STX1B</a></li> <li><a href="/wiki/HSF4" title="HSF4">HSF4</a></li> <li><a href="/wiki/CIITA" title="CIITA">CIITA</a></li> <li><a href="/wiki/PAM16" title="PAM16">PAM16</a></li> <li><a href="/wiki/NPRL3" title="NPRL3">NPRL3</a></li> <li><a href="/wiki/HN1L" title="HN1L">HN1L</a></li> <li><a href="/wiki/C16orf7" title="C16orf7">C16orf7</a></li> <li><a href="/wiki/HIRIP3" title="HIRIP3">HIRIP3</a></li> <li><a href="/wiki/PLEKHG4" title="PLEKHG4">PLEKHG4</a></li> <li><a href="/wiki/AKTIP" title="AKTIP">AKTIP</a></li> <li><a href="/wiki/ZNF19" title="ZNF19">ZNF19</a></li> <li><a href="/wiki/LITAF" title="LITAF">LITAF</a></li> <li><a href="/wiki/PYCARD" title="PYCARD">PYCARD</a></li> <li><a href="/wiki/JPH3" title="JPH3">JPH3</a></li> <li><a href="/wiki/KDM8" title="KDM8">KDM8</a></li> <li><a href="/wiki/EMP2" title="EMP2">EMP2</a></li> <li><a href="/wiki/TFAP4" title="TFAP4">TFAP4</a></li> <li><a href="/wiki/TXNL4B" title="TXNL4B">TXNL4B</a></li> <li><a href="/wiki/CENPT" title="CENPT">CENPT</a></li> <li><a href="/wiki/NFATC3" title="NFATC3">NFATC3</a></li></ul> </div></td></tr></tbody></table></div> <style data-mw-deduplicate="TemplateStyles:r68268331">.mw-parser-output .portalbox{padding:0;margin:0.5em 0;display:table;box-sizing:border-box;max-width:20ch;list-style:none}.mw-parser-output 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li{display:inline}.mw-parser-output .bandeau-portail-element{white-space:nowrap;margin:auto 1.5em}.mw-parser-output .bandeau-portail-icone{margin-left:0.5em}.mw-parser-output .bandeau-portail-texte>a:nth-child(1){font-weight:700}.mw-parser-output .ns-14 #bandeau-portail{width:242px;float:left;font-size:96%;text-align:right;margin:0;clear:left}.mw-parser-output .ns-14 #bandeau-portail li{margin-right:-17px}@media screen{html.skin-theme-clientpref-night .mw-parser-output .portalbox{background:transparent}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .pane{background:transparent}}</style><ul role="navigation" aria-label="Portals" class="noprint bandeau-portail" id="bandeau-portail"> <li class="bandeau-portail-element"><span class="bandeau-portail-icone"><span class="noviewer" typeof="mw:File"><a href="/wiki/%D9%85%D9%84%D9%81:1GZX_Haemoglobin.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/3/3d/1GZX_Haemoglobin.png/28px-1GZX_Haemoglobin.png" decoding="async" width="28" height="28" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/3d/1GZX_Haemoglobin.png/42px-1GZX_Haemoglobin.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/3d/1GZX_Haemoglobin.png/56px-1GZX_Haemoglobin.png 2x" data-file-width="1600" data-file-height="1600" /></a></span></span><span class="bandeau-portail-texte"><a href="/wiki/%D8%A8%D9%88%D8%A7%D8%A8%D8%A9:%D8%A7%D9%84%D9%83%D9%8A%D9%85%D9%8A%D8%A7%D8%A1_%D8%A7%D9%84%D8%AD%D9%8A%D9%88%D9%8A%D8%A9" title="بوابة:الكيمياء الحيوية">بوابة الكيمياء الحيوية</a></span></li> <li class="bandeau-portail-element"><span class="bandeau-portail-icone"><span class="noviewer" typeof="mw:File"><a href="/wiki/%D9%85%D9%84%D9%81:P_medicine.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/6/6d/P_medicine.svg/31px-P_medicine.svg.png" 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role="note" class="metadata plainlinks asbox stub"><table role="presentation"><tbody><tr class="noresize"><td><span typeof="mw:File"><a href="/wiki/%D9%85%D9%84%D9%81:Myoglobin.png" class="mw-file-description"><img alt="أيقونة بذرة" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/60/Myoglobin.png/20px-Myoglobin.png" decoding="async" width="20" height="20" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/60/Myoglobin.png/30px-Myoglobin.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/60/Myoglobin.png/40px-Myoglobin.png 2x" data-file-width="1159" data-file-height="1173" /></a></span></td><td><p class="asbox-body">هذه <a href="/wiki/%D9%88%D9%8A%D9%83%D9%8A%D8%A8%D9%8A%D8%AF%D9%8A%D8%A7:%D8%A8%D8%B0%D8%B1%D8%A9" title="ويكيبيديا:بذرة">بذرة</a> مقالة عن <a href="/wiki/%D8%A8%D8%B1%D9%88%D8%AA%D9%8A%D9%86" title="بروتين">بروتين</a> بحاجة للتوسيع. فضلًا <a class="external text" href="https://ar.wikipedia.org/w/index.php?title=NUPR1&action=edit">شارك</a> في تحريرها.</p></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r64177691" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r68124052" /></div><div role="navigation" class="navbox" aria-label="Navbox" style="padding:1px"><table class="nowraplinks hlist navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="row" class="navbox-group" style="width:12%">التصنيفات الطبية</th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0;text-align:right;"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/%D8%A7%D9%84%D9%88%D8%B1%D8%A7%D8%AB%D8%A9_%D8%A7%D9%84%D9%85%D9%86%D8%AF%D9%84%D9%8A%D8%A9_%D8%A7%D9%84%D8%A8%D8%B4%D8%B1%D9%8A%D8%A9_%D8%B9%D8%A8%D8%B1_%D8%A7%D9%84%D8%A5%D9%86%D8%AA%D8%B1%D9%86%D8%AA" title="الوراثة المندلية البشرية عبر الإنترنت">دليل الوراثة المندلية عند البشر (OMIM)</a>: <a rel="nofollow" class="external text" href="https://omim.org/entry/614812">614812</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:12%">المعرفات الخارجية</th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0;text-align:right;"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/%D9%85%D8%B4%D8%B1%D9%88%D8%B9_%D9%82%D8%A7%D8%B9%D8%AF%D8%A9_%D8%A8%D9%8A%D8%A7%D9%86%D8%A7%D8%AA_%D8%AC%D9%8A%D9%86%D9%88%D9%85_%D8%A5%D9%86%D8%B3%D9%86%D8%A8%D9%84" title="مشروع قاعدة بيانات جينوم إنسنبل">Ensembl Transcript ID</a>: <a rel="nofollow" class="external text" href="http://identifiers.org/ensembl/ENST00000395641">ENST00000395641</a></li> <li><a href="/wiki/%D9%86%D8%B8%D8%A7%D9%85_%D8%A7%D9%84%D9%84%D8%BA%D8%A9_%D8%A7%D9%84%D8%B7%D8%A8%D9%8A%D8%A9_%D8%A7%D9%84%D9%85%D9%88%D8%AD%D8%AF%D8%A9" title="نظام اللغة الطبية الموحدة">نظام اللغة الطبية الموحدة (UMLS CUI)</a>: <a rel="nofollow" class="external text" href="https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI%20Metathesaurus&code=C2829966">C2829966</a></li></ul> </div></td></tr></tbody></table></div></div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?useformat=desktop&type=1x1&usesul3=0" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">مجلوبة من «<a dir="ltr" href="https://ar.wikipedia.org/w/index.php?title=NUPR1&oldid=60755050">https://ar.wikipedia.org/w/index.php?title=NUPR1&oldid=60755050</a>»</div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/%D9%88%D9%8A%D9%83%D9%8A%D8%A8%D9%8A%D8%AF%D9%8A%D8%A7:%D8%AA%D8%B5%D9%81%D8%AD" title="ويكيبيديا:تصفح">تصنيف</a>: <ul><li><a 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cdx-button--icon-only" id="ca-subject-sticky-header" tabindex="-1" data-event-name="subject-sticky-header"><span class="vector-icon mw-ui-icon-article mw-ui-icon-wikimedia-article"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-history-sticky-header" tabindex="-1" data-event-name="history-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-history mw-ui-icon-wikimedia-wikimedia-history"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only mw-watchlink" id="ca-watchstar-sticky-header" tabindex="-1" data-event-name="watch-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-star mw-ui-icon-wikimedia-wikimedia-star"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-edit-sticky-header" tabindex="-1" data-event-name="wikitext-edit-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-wikiText mw-ui-icon-wikimedia-wikimedia-wikiText"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-ve-edit-sticky-header" tabindex="-1" data-event-name="ve-edit-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-edit mw-ui-icon-wikimedia-wikimedia-edit"></span> <span></span> </a> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only" id="ca-viewsource-sticky-header" tabindex="-1" data-event-name="ve-edit-protected-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-editLock mw-ui-icon-wikimedia-wikimedia-editLock"></span> <span></span> </a> </div> <div class="vector-sticky-header-buttons"> <button class="cdx-button cdx-button--weight-quiet mw-interlanguage-selector" id="p-lang-btn-sticky-header" tabindex="-1" data-event-name="ui.dropdown-p-lang-btn-sticky-header"><span class="vector-icon mw-ui-icon-wikimedia-language mw-ui-icon-wikimedia-wikimedia-language"></span> <span>6 لغات</span> </button> <a href="#" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive" id="ca-addsection-sticky-header" tabindex="-1" data-event-name="addsection-sticky-header"><span class="vector-icon mw-ui-icon-speechBubbleAdd-progressive mw-ui-icon-wikimedia-speechBubbleAdd-progressive"></span> <span>أضف موضوعًا</span> </a> </div> <div class="vector-sticky-header-icon-end"> <div class="vector-user-links"> </div> </div> </div> </div> </div> <div class="mw-portlet mw-portlet-dock-bottom emptyPortlet" id="p-dock-bottom"> <ul> </ul> </div> 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