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Abstract | Influence of Pulmonary Hypertension on Surgical PDA Ligation Outcomes in Preterm Neonates
<!DOCTYPE html> <html lang="en"> <head> <meta charset="utf-8"> <meta name="viewport" content="width=device-width, initial-scale=1.0" /> <meta name="viewport" content="width=device-width, initial-scale=1.0"> <link href="https://cdn.jsdelivr.net/npm/bootstrap@5.0.2/dist/css/bootstrap.min.css" rel="stylesheet" integrity="sha384-EVSTQN3/azprG1Anm3QDgpJLIm9Nao0Yz1ztcQTwFspd3yD65VohhpuuCOmLASjC" crossorigin="anonymous"> <script src="https://cdn.jsdelivr.net/npm/bootstrap@5.0.2/dist/js/bootstrap.bundle.min.js" integrity="sha384-MrcW6ZMFYlzcLA8Nl+NtUVF0sA7MsXsP1UyJoMp4YLEuNSfAP+JcXn/tWtIaxVXM" crossorigin="anonymous"></script> <link href="https://www.scivisionpub.com/css/style.css" rel="stylesheet" /> <link rel="stylesheet" href="https://cdn.jsdelivr.net/npm/bootstrap-icons@1.4.1/font/bootstrap-icons.css"> <link href="https://stackpath.bootstrapcdn.com/font-awesome/4.7.0/css/font-awesome.min.css" rel="stylesheet"> <script src="//www.google.com/recaptcha/api.js"></script> <title>Abstract | Influence of Pulmonary Hypertension on Surgical PDA Ligation Outcomes in Preterm Neonates</title> <meta name="keywords" content="Influence of Pulmonary Hypertension on Surgical PDA Ligation Outcomes in Preterm Neonates" /> <meta name="description" content="Influence of Pulmonary Hypertension on Surgical PDA Ligation Outcomes in Preterm Neonates" /> </head> <body> <nav class="navbar navbar-expand-lg navbar-light bg-white"> <div class="container"> <a class="navbar-brand" href="https://www.scivisionpub.com/" style="margin-left: -12px;"> <img src="https://www.scivisionpub.com/img/logo.jpg" alt="logo" height="75" /> </a><button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbarSupportedContent" aria-controls="navbarSupportedContent" aria-expanded="false" aria-label="Toggle navigation"> <span class="navbar-toggler-icon"></span> </button> <div class="collapse navbar-collapse" id="navbarSupportedContent"> <ul class="navbar-nav me-auto mb-2 mb-lg-0 px-5"> <li class="nav-item"> <a class="nav-link active" aria-current="page" href="https://www.scivisionpub.com/">Home</a> </li> <li class="nav-item"> <a class="nav-link" href="https://www.scivisionpub.com/all-journals">Journals</a> </li> <li class="nav-item"> <a class="nav-link" href="https://www.scivisionpub.com/submit-online">Submit Manuscript</a> </li> <li class="nav-item"> <a class="nav-link" href="https://www.scivisionpub.com/abstracting-indexing">Abstracting and Indexing</a> </li> <li class="nav-item"> <a class="nav-link" href="https://www.scivisionpub.com/contact">Contact Us</a> </li> </ul> </div> </div> </nav> <script src="https://ajax.googleapis.com/ajax/libs/jquery/3.2.1/jquery.min.js"></script> <script type="text/javascript"> /* $( window ).load(function() { $("#query").load("sql-query.php"); 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Lagatta, Evelyn M Kuhn, Stephanie S. Handler. </em></p> <p><p><strong>Background: </strong>Pulmonary hypertension (PH) increases mortality in infants with bronchopulmonary dysplasia (BPD). As practice has shifted towards expectant management of patent ductus arteriosus (PDA), there is limited data guiding treatment with PH.</p> <p><strong>Methods: </strong>Retrospective single center cohort study of neonates <32 weeks gestation who underwent surgical PDA ligation before discharge. Ductal gradients by echocardiogram defined PH severity: severe PH as bidirectional/ right to left shunting, mild-to-moderate PH as greater than half-systemic pressure, no PH as less than half-systemic pressure. Primary outcome was mortality. Secondary outcomes were length of stay (LOS), duration of ventilation, post-operative inotropes, steroids, systemic pulmonary vasodilators, and incidence of BPD.</p> <p><strong>Results: </strong>Eighty patients, median gestational age 25 (23-31) weeks, underwent surgical PDA ligation between 2010-2016. Ten had severe PH, 54 mild-to-moderate PH, and 16 no PH. Severe PH group had significantly longer LOS, 173 vs. 143 days (p=.05). PH cohort had higher surgical weight, 1.71 kg vs. 1.06 kg (p=0.04). All deaths occurred in the PH group (6% vs. 0%), p=NS. No significant difference in ventilation, inotropes, steroids, pulmonary vasodilators, and BPD. Although, statistically insignificant, the PH group had higher rates of tracheostomies (18.8% vs. 6.25%).</p> <p><strong>Conclusion: </strong>Premature infants requiring PDA ligation with severe PH had longer overall LOS. All mortality occurred in the PH group. More data is needed to determine effect of PDA on lung disease and the development of PH.</p> </p> <a href="https://www.scivisionpub.com/pdfs/influence-of-pulmonary-hypertension-on-surgical-pda-ligation-outcomes-in-preterm-neonates-2290.pdf" class="btn btn-danger btn-sm"><i class="bi bi-arrow-up-right-square"></i> View/Download pdf</a> </div> </div> </div> </section> <footer class="mt-3 bg-info pt-4 pb-1"> <div class="container"> <div class="row"> <div class="col-md-3"> <span style="border-bottom: 1px solid; font-weight:400">USEFUL LINKS</span> <ul class="list-unstyled" style="margin-top: 16px;"> <li><a style="color: white;" href="https://www.scivisionpub.com/index">Home</a></li> <li><a style="color: white;" href="https://www.scivisionpub.com/all-journals">Journals</a></li> <li><a style="color: white;" href="https://www.scivisionpub.com/why-scivision-publishers">Why with us</a></li> <li><a style="color: white;" href="https://www.scivisionpub.com/review-process">Review Process</a></li> </ul> </div> <div class="col-md-3"> <span style="border-bottom: 1px solid; font-weight:400">CONTACT US</span> <p style="margin-top: 16px;">SciVision Publishers LLC<br>108 West 13th Street<br>Wilmington<br>Delaware 19801<br>United States <br><a href="mailto:info@scivisionjournals.com">info@scivisionjournals.com</a> </p> </div> <div class="col-md-3"> <span style="border-bottom: 1px solid; font-weight:400">SOCIAL MEDIA</span> <ul class="list-unstyled list-inline" style="margin-top: 16px;"> <li><a style="color: white; font-size:x-large;" href="https://www.facebook.com/SciVisionpublishers" title="Facebook"><i class="fa fa-facebook"></i></a></li> <li><a style="color: white; font-size:x-large;" href="https://twitter.com/scivisionpub" title="Twitter"><i class="fa fa-twitter"></i></a></li> <li><a style="color: white; font-size:x-large;" href="http://linkedin.com/company/scivision-publishers" title="Linkedin"><i class="fa fa-linkedin"></i></a></li> <!-- <li><a style="color: white; font-size:x-large;" href="#" title="Pinterest"><i class="fa fa-pinterest"></i></a></li> --> </ul> </div> <div class="col-md-3"> <span style="border-bottom: 1px solid; font-weight:400">CERTIFICATE OF SERVICE</span> <div> <a href="https://www.scivisionpub.com/assets/pdf/SciVision-Publishers-LLC.pdf"><img class="img-thumbnail" style="background: transparent; margin-top: 1rem" src="https://www.scivisionpub.com/assets/img/certificate.jpeg" width="180px" alt="scilitLogo"></a> </div> </div> </div> <hr> <div class="row"> <div class="col-md-12 text-center"> <p> <span>© SciVision Publishers 2024 All right reserved.</span> </p> <span id="siteseal"> <script async type="text/javascript" src="https://seal.godaddy.com/getSeal?sealID=aH2qgB5zDtzxPTl9Q5NKcNGsSzhvB87jMFqeB7QBx8CNAV8JdhLTbQeBSfdX"> </script> </span> </div> </div> </div> </footer> <script src="https://www.scivisionpub.com/js/jquery.js"></script> <script src="https://cdn.jsdelivr.net/npm/@popperjs/core@2.9.2/dist/umd/popper.min.js" integrity="sha384-IQsoLXl5PILFhosVNubq5LC7Qb9DXgDA9i+tQ8Zj3iwWAwPtgFTxbJ8NT4GN1R8p" crossorigin="anonymous"></script> <script src="https://cdn.jsdelivr.net/npm/bootstrap@5.0.2/dist/js/bootstrap.min.js" integrity="sha384-cVKIPhGWiC2Al4u+LWgxfKTRIcfu0JTxR+EQDz/bgldoEyl4H0zUF0QKbrJ0EcQF" crossorigin="anonymous"></script> <script src="//code.tidio.co/eewcw9kd2uo3hrxdr2vmpjdd96tgakr3.js" async></script> </body> </html>