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}) })(jQuery); </script> </head> <body class="post-template-default single single-post postid-238 single-format-standard header-image full-width-content genesis-breadcrumbs-visible"><div class="site-container"><header class="site-header"><div class="wrap"><div class="title-area"><p class="site-title"><a href="https://www.thermofisher.com/" title="Thermo Fisher Scientific">Thermo Fisher Scientific</a></p><p class="site-description">Electron and cryo-electron microscopy stories and solutions about the advancement of cellular and structural biology</p></div><div class="widget-area header-widget-area"><section id="block-5" class="widget widget_block"><div class="widget-wrap"> <div class="wp-block-group"><div class="wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow"></div></div> </div></section> <section id="block-6" class="widget widget_block"><div class="widget-wrap"> <div class="wp-block-group"><div class="wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow"></div></div> </div></section> </div><div class="breadcrumb"><span class="breadcrumb-link-wrap"><a href="https://www.thermofisher.com/blog/?">Accelerating Science</a></span><span class="breadcrumb-link-wrap"><a class="breadcrumb-link" href="https://www.thermofisher.com/blog/atomic-resolution/"><span class="breadcrumb-link-text-wrap">Life in Atomic Resolution</span></a><meta ></span> <span aria-label="breadcrumb separator">/</span> <span class="breadcrumb-link-wrap"><a class="breadcrumb-link" href="https://www.thermofisher.com/blog/atomic-resolution/cryo-electron-microscopy-cryo-em/"><span class="breadcrumb-link-text-wrap">Cryo-Electron Microscopy (Cryo-EM)</span></a><meta ></span> <span aria-label="breadcrumb separator">/</span> <span class="breadcrumb-current-title">Cryo-EM University: An Online Electron Microscopy Curriculum</span></div></div></header><div class="site-inner"><div class="content-sidebar-wrap"><main class="content"><article class="post-238 post type-post status-publish format-standard has-post-thumbnail category-cryo-electron-microscopy-cryo-em category-general tag-cryo-electron-microscopy tag-cryo-em tag-cryo-em-single-particle-analysis tag-cryo-em-university tag-electron-microscopy tag-em-learning tag-fei tag-jacques-dubochet tag-joachim-frank tag-nih tag-nobel-prize tag-richard-henderson tag-single-particle-analysis tag-thermo-fisher-scientific tag-thermo-scientific entry" aria-label="Cryo-EM University: An Online Electron Microscopy Curriculum"><header class="entry-header"><h1 class="entry-title">Cryo-EM University: An Online Electron Microscopy Curriculum</h1> <span class="post-info-author"> By <a href="https://www.thermofisher.com/blog/author/thijsbressers/" title="Posts by Thijs Bressers" rel="author">Thijs Bressers</a> </span> <span class="post-info-date"> 04.04.2019 </span> </header><div class="entry-content"><p><a href="https://ter.li/ymqj1h">Electron microscopes</a> are transforming our knowledge of the world. Using beams of electrons to magnify structures up to 10 million times their actual size, these powerful instruments allow researchers to examine objects at levels of detail that were once unimaginable.</p> <p>Cryo-electron microscopy (cryo-EM) is the Nobel Prize-winning method researchers are using to better understand structures previously too large or complex to be studied, such as viruses and protein complexes. Scientists now have the ability to accelerate the path to new treatments and therapies for diseases such as Alzheimer’s, Parkinson’s, and Huntington’s, as well as cancers, AIDS, malaria, Zika and more.</p> <p><img decoding="async" src="https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2022/04/em-learning.png" width="762" height="217" /></p> <p> </p> <h3><strong>Dramatically lowering the EM learning curve</strong></h3> <p>In an effort to assist researchers in getting the most from their data and help train people on cryo-EM instruments, Thermo Fisher and the California Institute of Technology (Caltech) teamed up to offer <a href="https://ter.li/5sr8z7">Cryo-Electron Microscopy (EM) University</a>, part of the EM-Learning platform, which is a first-of-its-kind online training program designed to help researchers of all levels become proficient in the use of these powerful instruments.</p> <p>Funded by a three-year grant from the <a href="https://ter.li/mjamyz">National Institute of Health</a> and with lectures from Professor Grant Jensen from Caltech, EM-Learning.com is an extension of Thermo Fisher’s Cryo-EM School, originally a nine-week program at Leiden University in the Netherlands. While the in-person program was effective, Thermo Fisher decided to transform the curriculum into an online program consisting of both theoretical instruction and practical hands-on training to improve the flexibility of the course and reduce the number of hours researchers need to spend in the laboratory.</p> <p>By joining thermofisher.com/em-learning, participants can get both the theoretical and practical training they need as their schedules allow. They can also dramatically lower their learning curve on how to use an electron microscope to become more proficient on the instrument.</p> <p>Demand for learning more about <a href="https://ter.li/c613wn">cryo-EM</a> has been higher than ever since <a href="https://ter.li/d67iw4">Jacques Dubochet</a> from the University of Lausanne in Switzerland, <a href="https://ter.li/he8ima">Joachim Frank</a> from Columbia University in New York, and <a href="https://ter.li/0i0tdd">Richard Henderson</a> from Cambridge in the United Kingdom, won the Nobel Prize in Chemistry for their development of this method in 2017.</p> <p>The curriculum includes over 75 hours of instruction divided into a “learning” and “workflow” section. The “learning” section of the program includes 10 modules that show participants how to set up and use every part of the electron microscope including the accelerator, the condenser and projection lenses, and detectors and cameras. Participants will also learn how to prepare samples for exploration using electron microscopes and how to collect data using Thermo Fisher’s single particle analysis software. The end of each module includes questions that participants can answer to test their knowledge before advancing to the next one.</p> <p>After completing the learning section, participants are encouraged to watch 45 minutes of “workflow” videos that demonstrate the step-by-step process of using an electron microscope. These steps include, preparing a sample, freezing it, mounting the sample under the microscope and collecting the data from the generated image. The workflow section serves as a review of all the steps required for using a cryo-EM electron microscope.</p> <h3><strong>Designed for novices to experts of all ages</strong></h3> <p>Designed for researchers of all levels, EM Learning has attracted a wide range of participants since the program was first made available in November 2018. The program is getting tremendous response globally. The curriculum continues to serve as an educational platform to help the next generation of cryo-electron microscopists.</p> <h3><strong>Registration</strong></h3> <p>To register, please log in on <a href="https://ter.li/5sr8z7" target="_blank" rel="noopener noreferrer">thermofisher.com/em-learning</a>. Please note that the instruction videos are also available as step-by-step guide via our FREE Scientific Workflows App for <a href="https://ter.li/kxspkw">iOS</a> and <a href="https://ter.li/mr5rps">Android</a> operating systems. The free (lite) version is accessible via the link on the login screen of the App.</p> <p><em>Thijs Bressers is a Customer Experience Manager at Thermo Fisher Scientific.</em></p>  <div class="jp-relatedposts"> <div class="related-post related-1"> <a href="https://www.thermofisher.com/blog/atomic-resolution/what-is-cryo-em-what-is-cryo-electron-microscopy/"><img width="310" height="274" src="https://www.thermofisher.com/blog/atomic-resolution/wp-content/uploads/sites/22/2024/10/cryoEM-blog-virus-pore4-1920x600_Header-310x274.jpg" class="attachment-grid size-grid wp-post-image" alt="cryoEM-blog-virus pore" decoding="async" /></a> <span class="grid-content"> <h4 class="entry-title"><a href="https://www.thermofisher.com/blog/atomic-resolution/what-is-cryo-em-what-is-cryo-electron-microscopy/">What is cryo-EM?</a></h4> <p>Cryo-EM: cryo electron microscopy Cryo-electron microscopy (... </p> <a 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