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Strand-seq Core | Terry Fox Laboratory

<!DOCTYPE html> <html lang="en" dir="ltr" prefix="og: https://ogp.me/ns#"> <head> <meta charset="utf-8" /> <script async src="https://www.googletagmanager.com/gtag/js?id=G-EH6QSG2FJ8"></script> <script>window.dataLayer = window.dataLayer || [];function gtag(){dataLayer.push(arguments)};gtag("js", new Date());gtag("set", "developer_id.dMDhkMT", true);gtag("config", "G-EH6QSG2FJ8", {"groups":"default","page_placeholder":"PLACEHOLDER_page_location","allow_ad_personalization_signals":false});</script> <meta name="description" content="The Strand-seq Core (SCORE) at the BC Cancer Research Institute offers production of Strand-seq data on a fee-for-service basis using state of the art instrumentation and innovative protocols." /> <link rel="canonical" href="https://www.bccrc.ca/dept/tfl/dept/tfl/services/strand-seq-core" /> <meta name="Generator" content="Drupal 10 (https://www.drupal.org)" /> <meta name="MobileOptimized" content="width" /> <meta name="HandheldFriendly" content="true" /> <meta name="viewport" content="width=device-width, initial-scale=1.0" /> <style>.logo a {background-image: url(/dept/tfl/dept/tfl/sites/terryfoxlab.ca/files/BCClogo_Research_TerryFoxLaboratory_RGB.png);background-size: contain;}body .region__network .logo a {background-size: contain}</style> <link rel="icon" href="/dept/tfl/dept/tfl/themes/custom/bccrc/favicon.ico" type="image/vnd.microsoft.icon" /> <title>Strand-seq Core | Terry Fox Laboratory</title> <link rel="stylesheet" href="//use.typekit.net/rew6qot.css"> <link rel="stylesheet" media="all" href="/dept/tfl/sites/terryfoxlab.ca/files/css/css_AarQcrgLs31lcRjok1l-T7UghOMU01jnxnBu-hVrJTY.css?delta=0&amp;language=en&amp;theme=bccrc&amp;include=eJx1i0EKQyEMRC9k9UxJTKMQNZhI-bcvpYUuSjcz8OYNEm0qogtBbx6X9imJwIIaFATnZLBBNljzUvcx0Pwl-Uw7qN0b1-SXB4_36cF4X3uUT2dWHjwjVw7o6jmWiP7XBruD_O6veAIZDEUU" /> <link rel="stylesheet" media="all" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/4.7.0/css/font-awesome.min.css" /> <link rel="stylesheet" media="all" href="/dept/tfl/sites/terryfoxlab.ca/files/css/css_b1Imd5Zfo6d9UtggtC_ak93-Ac2c67PnthKR5yWdzt8.css?delta=2&amp;language=en&amp;theme=bccrc&amp;include=eJx1i0EKQyEMRC9k9UxJTKMQNZhI-bcvpYUuSjcz8OYNEm0qogtBbx6X9imJwIIaFATnZLBBNljzUvcx0Pwl-Uw7qN0b1-SXB4_36cF4X3uUT2dWHjwjVw7o6jmWiP7XBruD_O6veAIZDEUU" /> </head> <body class="colour--navy not-front path--node page--service"> <a href="#main-content" class="visually-hidden focusable skip-link"> Skip to main content </a> <div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas> <div class="main-container"> <header class="page--service page"> <div class="region__header--inner region--inner"> <section id="block-bccrc-breadcrumbs" class="block block--system-breadcrumb-block block-bccrc-breadcrumbs"> <nav class="breadcrumb" role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/dept/tfl/dept/tfl/">Terry Fox Laboratory</a> </li> <li> <a href="/dept/tfl/dept/tfl/services">Core Facilities</a> </li> <li> Strand-seq Core </li> </ol> </nav> </section> <section id="block-bccrc-page-title" class="block block--page-title-block block-bccrc-page-title"> <h1><span>Strand-seq Core</span> </h1> </section> </div> </header> <section class="region region__highlight"> <div class="region__highlight--inner region--inner"> <div data-drupal-messages-fallback class="hidden"></div> </div> </section> <main role="main"> <a id="main-content" tabindex="-1"></a> <div class="layout-content"> <section class="region region__content"> <div class="region__content--inner region--inner"> <section id="block-bccrc-content" class="block block--system-main-block block-bccrc-content"> <article class="node node--service full"> <div class="field field--body"><p>The Strand-seq Core (SCORE) at the BC Cancer Research Institute offers production of Strand-seq data on a fee-for-service basis using state of the art instrumentation and innovative protocols. Experienced Core staff support the needs of researchers with tailored Strand-seq workflows including the culture of primary cells or cell lines, construction of single-cell libraries using the <a href="https://www.cellenion.com/products/cellenone/">cellenONE X1</a> nanolitre liquid handler and cell isolation system, and DNA sequencing with the <a href="https://www.elementbiosciences.com/products/aviti">Element Biosciences AVITI</a> instrument, compatible with standard Illumina sequencing libraries.</p><p>Please see common SCORE services and pricing (in CAD) on this page. We welcome enquiries about custom and standard services using available instruments at the SCORE.</p></div> </article> <section class="layout layout__columns layout__parent__node group paragraph paragraph--type--columns paragraph--view-mode--default" id="paragraph--283"> <h2 class="section__title">SCORE Services</h2> <div class="columns columns--3"> <h2 class="section__title">Strand-seq Data Production</h2> <div class="layout layout__column layout__parent__paragraph paragraph paragraph--type--column paragraph--view-mode--default" id="paragraph--280"> <img loading="lazy" src="/dept/tfl/dept/tfl/sites/terryfoxlab.ca/files/styles/teaser/public/2025-03/Strand-seq%20data.png?itok=bhTjUYQv" width="600" height="450" alt="" /> <div class="field--field_paragraph_text"> <p>Example of single Strand-seq data used for haplotyping, mapping of sister chromatid exchange events (asterisks), structural genomic variation including polymorphic inversions (see e.g. chr 8, 15 and 16) and copy number variations.&nbsp;</p> </div> </div> <h2 class="section__title">AVITI Next-Gen DNA Sequencing</h2> <div class="layout layout__column layout__parent__paragraph paragraph paragraph--type--column paragraph--view-mode--default" id="paragraph--281"> <img loading="lazy" src="/dept/tfl/dept/tfl/sites/terryfoxlab.ca/files/styles/teaser/public/2025-02/Element-AVITI24_still_Feb5_noshadow.png?itok=VICaiUj3" width="600" height="450" alt="" /> <div class="field--field_paragraph_text"> <p>Produce high quality &gt;Q40 data without index hopping from next-generation DNA sequencing libraries. Compatible with Illumina-based or Element Biosciences Elevate libraries.</p> </div> </div> <h2 class="section__title">cellenONE Nanolitre Dispensing</h2> <div class="layout layout__column layout__parent__paragraph paragraph paragraph--type--column paragraph--view-mode--default" id="paragraph--282"> <img loading="lazy" src="/dept/tfl/dept/tfl/sites/terryfoxlab.ca/files/styles/teaser/public/2025-02/6b0xvptk.png?itok=v-DTSX45" width="600" height="450" alt="" /> <div class="field--field_paragraph_text"> <p>Perform single cell isolation or nanolitre dispensing on a wide variety of substrates including 72-well Terasaki plates, 96-well plates, 384-well plates, microscope slides, or 5184-nanowell Takara ICELL8 chips.</p> </div> </div> </div> </section> <section class="layout layout__expanding layout__parent__node has-expanding-text paragraph paragraph--type--expanding paragraph--view-mode--default" id="paragraph--271"> <h2 class="section__title" data-expand="field--field_text">Strand-seq Technology</h2><button class="icon" data-expand></button> <div class="field field--field_text"> <p>The single cell Strand-seq technology, developed in the Lansdorp lab (1), has proven to be a key technology to advance a wide variety of studies.&nbsp;</p><p>For example, Strand-seq has been used for the phasing of genomes and mapping of structural variants in human genomes in studies published in Nature (2,3), Cell (4) and Science (5). In a local collaboration we recently showed that, using a combination of long-read and Strand-seq data from the same person, it is possible to assign a parent of origin to any allele using only a blood sample from the proband (6). For this <a href="https://www.bcgsc.ca/research/parent-origin-aware-genomic-analysis-poaga">Parent-of-Origin-Aware genomic analysis (POAga)</a>, Strand-seq data is used to generate chromosome-length haplotype information (7) to complement ONT long read whole genome sequence data as well as data about DNA methylation at imprint locations. By combining data from the two different sequencing techniques, any allele on any chromosome in a person can now be assigned to its parent of origin without analysis of parental DNA (6).</p><p>Strand-seq library production is currently performed in nanoliter volumes in open nanoliter arrays (8). This advance has resulted in a major increase in the number and quality of Strand-seq libraries that can be produced.</p><p><strong>Parent-of-Origin-Aware Genomic Analysis</strong></p><p><a href="https://www.bccrc.ca/dept/tfl/dept/tfl/dept/tfl/sites/terryfoxlab.ca/files/Example%201%20cell%20revised.png"><strong>Example of a single Strand-seq data file</strong></a></p><p><a href="https://www.bccrc.ca/dept/tfl/dept/tfl/dept/tfl/sites/terryfoxlab.ca/files/Example%2010%20cells%20revised.png"><strong>Example of multiple &nbsp;Strand-seq data files</strong></a></p><ol><li>Falconer, E., Hills, M., Naumann, U., Poon, S.S., Chavez, E.A., Sanders, A.D., Zhao, Y., Hirst, M. and Lansdorp, P.M. (2012) DNA template strand sequencing of single-cells maps genomic rearrangements at high resolution. Nat Methods, 9, 1107-1112.</li><li>Liao, W.W., Asri, M., Ebler, J., Doerr, D., Haukness, M., Hickey, G., Lu, S., Lucas, J.K., Monlong, J., Abel, H.J. et al. (2023) A draft human pangenome reference. Nature, 617, 312-324.</li><li>Logsdon, G.A., Rozanski, A.N., Ryabov, F., Potapova, T., Shepelev, V.A., Catacchio, C.R., Porubsky, D., Mao, Y., Yoo, D., Rautiainen, M. et al. (2024) The variation and evolution of complete human centromeres. Nature, 629, 136-145.</li><li>Porubsky, D., Hops, W., Ashraf, H., Hsieh, P., Rodriguez-Martin, B., Yilmaz, F., Ebler, J., Hallast, P., Maria Maggiolini, F.A., Harvey, W.T. et al. (2022) Recurrent inversion polymorphisms in humans associate with genetic instability and genomic disorders. Cell, 185, 1986-2005 e1926.</li><li>Ebert, P., Audano, P.A., Zhu, Q., Rodriguez-Martin, B., Porubsky, D., Bonder, M.J., Sulovari, A., Ebler, J., Zhou, W., Serra Mari, R. et al. (2021) Haplotype-resolved diverse human genomes and integrated analysis of structural variation. Science, 372.</li><li>Akbari, V., Hanlon, V.C.T., O鈥橬eill, K., Lefebvre, L., Schrader, K.A., Lansdorp, P.M. and Jones, S.J.M. (2022) Parent-of-origin detection and chromosome-scale haplotyping using long-read DNA methylation sequencing and Strand-seq. Cell Genomics, 100233.</li><li>Porubsky, D., Sanders, A.D., van Wietmarschen, N., Falconer, E., Hills, M., Spierings, D.C., Bevova, M.R., Guryev, V. and Lansdorp, P.M. (2016) Direct chromosome-length haplotyping by single-cell sequencing. Genome Res, 26, 1565-1574.</li><li>Hanlon, V.C.T., Chan, D.D., Hamadeh, Z., Wang, Y., Mattsson, C.A., Spierings, D.C.J., Coope, R.J.N. and Lansdorp, P.M. (2022) Construction of Strand-seq libraries in open nanoliter arrays. Cell Rep Methods, 2, 100150</li></ol></div> </section> <section class="layout layout__expanding layout__parent__node has-expanding-text paragraph paragraph--type--expanding paragraph--view-mode--default" id="paragraph--266"> <h2 class="section__title" data-expand="field--field_text">Strand-seq or Single-cell WGS Data Production Package</h2><button class="icon" data-expand></button> <div class="field field--field_text"> <p>The SCORE will typically produce at least 20 good quality single-cell Strand-seq libraries with 10 million read pairs for each sample. Higher numbers of good libraries and greater sequencing depth are often obtained or a higher thresholds can be made upon request.</p><p>The above sequencing is sufficient for Strand-seq applications such as chromosome-length phasing of haplotypes for<a href="https://www.bcgsc.ca/research/parent-origin-aware-genomic-analysis-poaga"> POAga</a> and large structural variation detection, but genome assembly studies may require deeper genome coverage. Sample and sequencing costs may vary depending on the desired number of libraries, their desired sequencing depth and the possibility to make and sequence libraries concurrently with samples from different experiments.</p><p>The standard Strand-seq package includes cell culture with BrdU, preparation and fluorescence-activated cell sorting (FACS) of fixed nuclei, library preparation using the cellenONE, size selection and quality control of libraries, AVITI Next-generation DNA sequencing, and Strand-seq data processing. For other single-cell whole genome sequencing (WGS) applications, cell culture, nuclei preparation, and FACS can be omitted to reduce costs. Whole blood (2 x 6 mL sodium heparin) or cultured cell lines (frozen in cryovials or in culture media) are acceptable for submission. Alternatively, Coriell catalogued cell lines can be order by the SCORE. The SCORE will provide FastQ files and basic sequencing metrics upon request. We can offer assistance using Strand-seq bioinformatics tools.</p><p><strong>Strand-seq Data Production Package</strong></p><p>路 Cell Culture, Nuclei Preparation &amp; FACS - $200 / sample</p><p>路 Nanolitre Library Preparation &amp; QC - $100 / sample (in a batch of ~15-20 samples)</p><p>路 AVITI Sequencing and Data Processing - $1770 (2 x 75 bp) or $2760 (2 x 150 bp) / run (multiplexed pool of ~15-20 samples)</p><p>路 Labour - $40 / hour</p><p>路 A surcharge is applied for external users (25%) and corporate users (40%) of the total cost, and may include an additional $500 administrative fee per invoice billed quarterly.</p><p>Typical cost per sample (20+ good cells, &gt; 10 million read pairs): $500-1000 depending on pooling of libraries and sequencing strategy.</p></div> </section> <section class="layout layout__expanding layout__parent__node has-expanding-text paragraph paragraph--type--expanding paragraph--view-mode--default" id="paragraph--267"> <h2 class="section__title" data-expand="field--field_text">AVITI Next-generation DNA Sequencing Services</h2><button class="icon" data-expand></button> <div class="field field--field_text"> <p>The Element Biosciences AVITI instrument produces &gt;Q40 high quality Next-generation DNA sequencing data with negligible sample-index misassignment (index hopping) using avidity sequencing of DNA polonies generated by rolling circle amplification.</p><p>Despite different sequencing chemistries, Cloudbreak Freestyle technology allows direct sequencing compatibility with Illumina-based libraries. AVITI sequencing kits can provide over 1 billion read pairs per run with significantly lower costs per Gigabase of data at this scale than standard benchtop Illumina sequencers. The SCORE provides direct AVITI next-generation short read sequencing services for any compatible user sequencing libraries or as a part of the Strand-seq Data Production Package.</p><p><strong>AVITI Sequencing</strong></p><p>路 AVITI 150 cycle High (2 x 75 bp, &gt;900 million Read Pairs, &gt;135 Gb) - $1770 / run</p><p>路 AVITI 300 cycle High (2 x 150 bp, &gt;900 million Read Pairs, &gt;270 Gb) - $2760 / run</p><p>路 A surcharge is applied for external users (25%) and corporate users (40%) of the total cost, and may include an additional $500 administrative fee per invoice billed quarterly.</p></div> </section> <section class="layout layout__expanding layout__parent__node has-expanding-text paragraph paragraph--type--expanding paragraph--view-mode--default" id="paragraph--268"> <h2 class="section__title" data-expand="field--field_text">Custom cellenONE Cell Isolation or Nanolitre Spotting</h2><button class="icon" data-expand></button> <div class="field field--field_text"> <p>The Cellenion cellenONE X1 is a single-cell isolation and pico- to nanolitre volume liquid handler using a contactless piezo dispense capillary.&nbsp;</p><p>The cellenONE uses gentle acoustic waves to generate droplets, allowing for more gentle isolation of cells for cloning applications with higher cell viability compared to standard flow cytometry cell sorters. Single cells can be isolated into a wide range of formats, including 72-well Terasaki plates, 96-well plates, 384-well plates, microscope slides, or 5184-nanowell Takara ICELL8 chips. This instrument is used for single-cell isolation and nanolitre reagent dispensing for Strand-seq library preparation. Instrument operation is managed by trained SCORE personnel only.</p><p><strong>Custom cellenONE Services</strong></p><p>路 cellenONE Spotting Session - $60 / session</p><p>路 Labour - $40 / hour</p><p>路 A surcharge is applied for external users (25%) and corporate users (40%) of the total cost, and may include an additional $500 administrative fee per invoice billed quarterly.</p></div> </section> <section class="layout layout__expanding layout__parent__node has-expanding-text paragraph paragraph--type--expanding paragraph--view-mode--default" id="paragraph--278"> <h2 class="section__title" data-expand="field--field_text">Sample Workflow</h2><button class="icon" data-expand></button> <div class="field field--field_text"> <p><strong>External Collaboration</strong></p><p>For collaborators outside UBC and the BC Cancer Agency, service/material transfer agreements need to be set up before samples can be received and processed. Please contact Dr. Peter Lansdorp, using the contact form below, and provide relevant details for collaboration requests.</p><p><strong>Workflow</strong></p><p>1. Send a message through the online form on this page for any inquiries for Strand-seq or other AVITI and cellenONE services. The SCORE can help determine the best suited conditions and strategies for the application.</p><p>2. Complete any statements of work (SOW) or material transfer agreements (MTA) as applicable.</p><p>3. When ready to submit samples, detailed sample shipping instructions will be provided. The following sample formats are acceptable:</p><p>&nbsp; &nbsp; &nbsp;a. Sample information for cell line from Coriell to be ordered and shipped by the SCORE directly</p><p>&nbsp; &nbsp; &nbsp;b. Shipped viable cells in culture flasks at room temperature</p><p>&nbsp; &nbsp; &nbsp;c. Shipped viable cells frozen in cryovials on dry ice</p><p>&nbsp; &nbsp; &nbsp;d. Shipped fresh blood sample in 2 x 6 mL sodium heparin tubes at room temperature</p><p>4. Demultiplexed FastQ files will be provided after sequencing is complete.</p><p>5. Invoices will be sent for billing via wire transfer.</p></div> </section> <section class="layout layout__expanding layout__parent__node has-expanding-text paragraph paragraph--type--expanding paragraph--view-mode--default" id="paragraph--279"> <h2 class="section__title" data-expand="field--field_text">Selected Bioinformatics Tools for Strand-Seq</h2><button class="icon" data-expand></button> <div class="field field--field_text"> <p>breakpointR - <a href="https://github.com/daewoooo/breakpointR ">https://github.com/daewoooo/breakpointR&nbsp;</a></p><p>ASHLEYS QC -<a href="//github.com/friendsofstrandseq/ashleys-qc "> https://github.com/friendsofstrandseq/ashleys-qc&nbsp;</a></p><p>StrandPhaseR - <a href="https://github.com/daewoooo/StrandPhaseR ">https://github.com/daewoooo/StrandPhaseR&nbsp;</a></p><p>InvertypeR - <a href="https://github.com/vincent-hanlon/InvertypeR">https://github.com/vincent-hanlon/InvertypeR</a></p></div> </section> <section class="layout layout__profiles layout__parent__node paragraph paragraph--type--profiles paragraph--view-mode--default" id="paragraph--264"> <h2 class="section__title">Core Director </h2> <div class="profiles"><article class="node node--profile teaser"> <a class="picture" href="/dept/tfl/dept/tfl/people/peter-m-lansdorp" ><figure> <img loading="lazy" src="/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/sites/terryfoxlab.ca/files/styles/profile/public/2023-05/PLansdorp-he.jpg?itok=XxrI9GP_" width="580" height="460" alt="" /> </figure></a> <section> <h3 class="node__title"> <a href="/dept/tfl/dept/tfl/people/peter-m-lansdorp" rel="bookmark">Peter M Lansdorp, MD, PhD, FRS(C)</a> </h3> <div class="field field--field_profile_title"> <div class="field field--item field--field_profile_title">Distinguished Scientist, Terry Fox Laboratory, BC Cancer</div> </div> <div class="contact"> <div class="field field--field_phone_number"><a href="tel:604-675-8135">604-675-8135</a></div> <a href= "https://www.bccrc.ca/dept/tfl/dept/tfl/contact/165" class="more">Send message</a> <a href="/dept/tfl/dept/tfl/people/peter-m-lansdorp" class="more" rel="bookmark">Bio <i class="fa fa-chevron-right"></i></a> </div> </section> </article> </div> </section> <section class="layout layout__profiles layout__parent__node paragraph paragraph--type--profiles paragraph--view-mode--default" id="paragraph--265"> <h2 class="section__title">Core Team</h2> <div class="profiles"><article class="node node--profile teaser"> <figure> <img loading="lazy" src="/dept/tfl/sites/terryfoxlab.ca/files/styles/profile/public/2019-07/DSC09180.jpg?itok=P6CxWXZc" width="580" height="460" alt="" /> </figure> <section> <h3 class="node__title"> Daniel D Chan </h3> <div class="field field--field_profile_title"> <div class="field field--item field--field_profile_title">Research Projects Coordinator</div> </div> <div class="field field--field_labs"> <div class="field field--item field--field_labs"><a href="/dept/tfl/dept/tfl/labs/lansdorp-lab" hreflang="en">Lansdorp Lab</a></div> </div> <div class="contact"> <div class="field field--field_phone_number"><a href="tel:604-675-8000ext.7774">604-675-8000 ext. 7774</a></div> <a href= "https://www.bccrc.ca/dept/tfl/dept/tfl/contact/162" class="more">Send message</a> </div> </section> </article> <article class="node node--profile teaser"> <figure> <img loading="lazy" src="/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/sites/terryfoxlab.ca/files/styles/profile/public/2019-05/BCPCM-portrait.png?itok=nEtgTObd" width="580" height="460" alt="" /> </figure> <section> <h3 class="node__title"> Tiffany Leung </h3> <div class="field field--field_profile_title"> <div class="field field--item field--field_profile_title">Bioinformatician</div> </div> <div class="field field--field_labs"> <div class="field field--item field--field_labs"><a href="/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/labs/lansdorp-lab" hreflang="en">Lansdorp Lab</a></div> </div> <div class="contact"> <div class="field field--field_phone_number"><a href="tel:604-675-8000Ext.7773">604-675-8000 Ext. 7773</a></div> </div> </section> </article> <article class="node node--profile teaser"> <figure> <img loading="lazy" src="/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/dept/tfl/sites/terryfoxlab.ca/files/styles/profile/public/2019-08/DSC06023%20for%20new%20website_0.jpg?itok=HrAO-U98" width="580" height="460" alt="" /> </figure> <section> <h3 class="node__title"> Amy Miao Yu, PMP </h3> <div class="field field--field_profile_title"> <div class="field field--item field--field_profile_title">Projects Team Leader</div> </div> <div class="field field--field_labs"> <div class="field field--item field--field_labs"><a href="/dept/tfl/dept/tfl/labs/kuchenbauer-lab" hreflang="en">Kuchenbauer Lab</a></div> <div class="field field--item field--field_labs"><a href="/dept/tfl/dept/tfl/labs/lansdorp-lab" hreflang="en">Lansdorp Lab</a></div> <div class="field field--item field--field_labs"><a href="/dept/tfl/dept/tfl/labs/stirling-lab" hreflang="en">Stirling Lab</a></div> <div class="field field--item field--field_labs"><a href="/dept/tfl/dept/tfl/labs/collings-stevens-chronic-leukemia-research-laboratory" hreflang="en">Collings Stevens Chronic Leukemia Research Laboratory</a></div> <div class="field field--item field--field_labs"><a href="/dept/tfl/dept/tfl/labs/humphries-lab" hreflang="en">Humphries Lab</a></div> </div> <div class="contact"> <div class="field field--field_phone_number"><a href="tel:604-675-8128">604-675-8128</a></div> <a href= "https://www.bccrc.ca/dept/tfl/dept/tfl/contact/84" class="more">Send message</a> </div> </section> </article> </div> </section> <section class="layout layout__webform"> <div class="field field--webform"><form class="webform-submission-form webform-submission-add-form webform-submission-contact-strand-core-form 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target="_blank">Services</a></li><li><a href="https://www.bccrc.ca/dept/et/news" target="_blank">News & Events</a></li><li><a href="https://www.bccrc.ca/dept/et/students-trainees" target="_blank">Students & Trainees</a></li><li><a href="https://www.bccrc.ca/dept/et/careers" target="_blank">Careers</a></li></ul></li><li class="depth--1 external microsite"><a href="https://www.bccrc.ca/dept/cid" class="depth--1 external microsite">Clinical Research</a><ul class="depth--2 microsite" id="Clinical-Research"><li class="title"><button data-toggle-body="network--open" class="departments">Departments</button><h2 class="site__title"><a href="https://www.bccrc.ca/dept/cid">Clinical Research</a></h2></li><li><a href="https://www.bccrc.ca/dept/cid/about-us" target="_blank">About Us</a></li><li><a href="https://www.bccrc.ca/dept/cid/people" target="_blank">People</a></li><li><a href="https://www.bccrc.ca/dept/cid/programs" target="_blank">Programs</a></li><li><a href="https://www.bccrc.ca/dept/cid/services" target="_blank">Services</a></li><li><a href="https://www.bccrc.ca/dept/cid/news" target="_blank">News & Events</a></li><li><a href="https://www.bccrc.ca/dept/cid/students-trainees" target="_blank">Students & Trainees</a></li><li><a href="https://www.bccrc.ca/dept/cid/careers" target="_blank">Careers</a></li></ul></li><li class="depth--1 external microsite"><a href="https://www.bccrc.ca/dept/drc" class="depth--1 external microsite">Deeley Research Centre</a><ul class="depth--2 microsite" id="Deeley-Research-Centre"><li class="title"><button data-toggle-body="network--open" class="departments">Departments</button><h2 class="site__title"><a href="https://www.bccrc.ca/dept/drc">Deeley Research Centre</a></h2></li><li><a href="https://www.bccrc.ca/dept/drc/about-us" target="_blank">About Us</a></li><li><a href="https://www.bccrc.ca/dept/drc/people" target="_blank">People</a></li><li><a href="https://www.bccrc.ca/dept/drc/services" target="_blank">Services</a></li><li><a href="https://www.bccrc.ca/dept/drc/news" target="_blank">News & Events</a></li><li><a href="https://www.bccrc.ca/dept/drc/students-trainees" target="_blank">Students & Trainees</a></li><li><a href="https://www.bccrc.ca/dept/drc/careers" target="_blank">Careers</a></li><li><a href="https://www.bccrc.ca/dept/drc/programs" target="_blank">Programs</a></li></ul></li><li class="external depth--1"><a href="http://www.bccancer.bc.ca" class="external depth--1">BC Cancer</a></li><li class="external depth--1"><a href="https://bccancerfoundation.com/" class="external depth--1">BC Cancer Foundation</a></li></ul> </section> <section id="block-shareblock" class="block block--share-block block-shareblock"> <div class="share"><span class="label">Share</span> <a href="https://www.facebook.com/sharer/sharer.php?u=https%3A%2F%2Fwww.bccrc.ca%2Fdept%2Ftfl%2Fdept%2Ftfl%2Fservices%2Fstrand-seq-core" target="_blank"><i class="fa fa-facebook"></i></a> <a 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