CINXE.COM
{"markup":"\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\n \u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022\n xmlns:content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022\n xmlns:dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022\n xmlns:foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022\n xmlns:og=\u0022http:\/\/ogp.me\/ns#\u0022\n xmlns:rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022\n xmlns:sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022\n xmlns:sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022\n xmlns:skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022\n xmlns:xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022\n xmlns:mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\n \u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/www.biorxiv.org\/sites\/default\/files\/js\/js_waP91NpgGpectm_6Y2XDEauLJ8WCSCBKmmA87unpp2E.js\u0022\u003E\u003C\/script\u003E\n\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/www.googletagmanager.com\/gtag\/js?id=G-RZD586MC3Q\u0022\u003E\u003C\/script\u003E\n\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\nwindow.dataLayer = window.dataLayer || [];function gtag(){dataLayer.push(arguments)};gtag(\u0022js\u0022, new Date());gtag(\u0022set\u0022, \u0022developer_id.dMDhkMT\u0022, true);gtag(\u0022config\u0022, \u0022G-RZD586MC3Q\u0022, {\u0022groups\u0022:\u0022default\u0022,\u0022anonymize_ip\u0022:true});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\n\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/biorxiv\\\/early\\\/2024\\\/11\\\/13\\\/2023.03.16.532874.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/biorxiv\\\/early\\\/2024\\\/11\\\/13\\\/2023.03.16.532874.atom\u0022,\u0022jcode\u0022:\u0022biorxiv\u0022}},\u0022markup\u0022:[{\u0022requested\u0022:\u0022expansion\u0022,\u0022variant\u0022:\u0022expansion\u0022,\u0022view\u0022:\u0022full\u0022,\u0022pisa\u0022:\u0022\u0022},{\u0022requested\u0022:\u0022expansion\u0022,\u0022variant\u0022:\u0022expansion\u0022,\u0022view\u0022:\u0022full\u0022,\u0022pisa\u0022:\u0022\u0022},{\u0022requested\u0022:\u0022expansion\u0022,\u0022variant\u0022:\u0022expansion\u0022,\u0022view\u0022:\u0022full\u0022,\u0022pisa\u0022:\u0022\u0022}]},\u0022googleanalytics\u0022:{\u0022account\u0022:[\u0022G-RZD586MC3Q\u0022],\u0022trackOutbound\u0022:1,\u0022trackMailto\u0022:1,\u0022trackDownload\u0022:1,\u0022trackDownloadExtensions\u0022:\u00227z|aac|arc|arj|asf|asx|avi|bin|csv|doc(x|m)?|dot(x|m)?|exe|flv|gif|gz|gzip|hqx|jar|jpe?g|js|mp(2|3|4|e?g)|mov(ie)?|msi|msp|pdf|phps|png|ppt(x|m)?|pot(x|m)?|pps(x|m)?|ppam|sld(x|m)?|thmx|qtm?|ra(m|r)?|sea|sit|tar|tgz|torrent|txt|wav|wma|wmv|wpd|xls(x|m|b)?|xlt(x|m)|xlam|xml|z|zip\u0022,\u0022trackColorbox\u0022:1},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u0022sites\\\/all\\\/modules\\\/contrib\\\/google_analytics\\\/googleanalytics.js\u0022:1,\u0022https:\\\/\\\/www.googletagmanager.com\\\/gtag\\\/js?id=G-RZD586MC3Q\u0022:1,\u00220\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\n\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022https:\/\/www.biorxiv.org\/sites\/default\/files\/advagg_css\/css__KwIbTmK5u_TU0NIDnj2cXC8qhcT3ubSigju5zweyvGo__s9nWpCT9viPWF_nkkvgfkyDAdML18ZKPz5hgnPPzHHQ__EJK5Ll7b5lGK3vCcC61vJSpnnlwWCn8d6_LJW7hCX3M.css\u0022 media=\u0022all\u0022 \/\u003E\n\u003Clink rel=\u0027stylesheet\u0027 type=\u0027text\/css\u0027 href=\u0027\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0027 \/\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-biorxiv-tab-data\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022 \u003E\n \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-biorxiv-supplementary-fragment\u0022 \u003E\n \n \n \n \u003Cdiv class=\u0022pane-content\u0022\u003E\n \u003Cdiv class=\u0022elements-supp-frag-data highwire-markup\u0022 id=\u0022supp-frag-data\u0022\u003E\u003Cdiv class=\u0022item-list\u0022\u003E\u003Cul class=\u0022supp-frag-data-list clearfix\u0022 id=\u0022supp-frag\u0022\u003E\u003Cli class=\u0022first\u0022\u003E\u003Cdiv class=\u0022element-supp-frag-data clearfix supplementary-material-caption\u0022\u003E\u003Cdiv class=\u0022highwire-markup\u0022\u003E\u003Cdiv xmlns=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022 class=\u0022content-block-markup\u0022 xmlns:xhtml=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022\u003E\u003Cdiv class=\u0022supplementary-material-expansion\u0022 id=\u0022DC1\u0022\u003E\u003Cspan class=\u0022highwire-journal-article-marker-start\u0022\u003E\u003C\/span\u003E\u003Cspan class=\u0022supplementary-material-label\u0022\u003ESupplemental Figures, Materials and Methods\u003C\/span\u003E\u003Cspan class=\u0022inline-linked-media-wrapper\u0022\u003E\u003Cspan id=\u0022DC1\u0022 class=\u0022inline-linked-media\u0022\u003E\u003Ca href=\u0022https:\/\/www.biorxiv.org\/content\/biorxiv\/early\/2024\/11\/13\/2023.03.16.532874\/DC1\/embed\/media-1.pdf?download=true\u0022 class=\u0022\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003E\u003Cspan class=\u0022icon-download-alt\u0022\u003E\u003C\/span\u003E[supplements\/532874_file05.pdf]\u003C\/a\u003E\u003C\/span\u003E\u003C\/span\u003E\u003Cspan class=\u0022highwire-journal-article-marker-end\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cspan id=\u0022related-urls\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/li\u003E\u003Cli\u003E\u003Cdiv class=\u0022element-supp-frag-data clearfix supplementary-material-caption\u0022\u003E\u003Cdiv class=\u0022highwire-markup\u0022\u003E\u003Cdiv xmlns=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022 class=\u0022content-block-markup\u0022 xmlns:xhtml=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022\u003E\u003Cdiv class=\u0022supplementary-material-expansion\u0022 id=\u0022DC2\u0022\u003E\u003Cspan class=\u0022highwire-journal-article-marker-start\u0022\u003E\u003C\/span\u003E\u003Cspan class=\u0022supplementary-material-label\u0022\u003ESupplemental Table 1\u003C\/span\u003E\u003Cspan class=\u0022inline-linked-media-wrapper\u0022\u003E\u003Cspan id=\u0022DC2\u0022 class=\u0022inline-linked-media\u0022\u003E\u003Ca href=\u0022https:\/\/www.biorxiv.org\/content\/biorxiv\/early\/2024\/11\/13\/2023.03.16.532874\/DC2\/embed\/media-2.xlsx?download=true\u0022 class=\u0022\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003E\u003Cspan class=\u0022icon-download-alt\u0022\u003E\u003C\/span\u003E[supplements\/532874_file06.xlsx]\u003C\/a\u003E\u003C\/span\u003E\u003C\/span\u003E\u003Cspan class=\u0022highwire-journal-article-marker-end\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cspan id=\u0022related-urls\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/li\u003E\u003Cli class=\u0022last\u0022\u003E\u003Cdiv class=\u0022element-supp-frag-data clearfix supplementary-material-caption\u0022\u003E\u003Cdiv class=\u0022highwire-markup\u0022\u003E\u003Cdiv xmlns=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022 class=\u0022content-block-markup\u0022 xmlns:xhtml=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022\u003E\u003Cdiv class=\u0022supplementary-material-expansion\u0022 id=\u0022DC3\u0022\u003E\u003Cspan class=\u0022highwire-journal-article-marker-start\u0022\u003E\u003C\/span\u003E\u003Cspan class=\u0022supplementary-material-label\u0022\u003ESupplemental Table 2\u003C\/span\u003E\u003Cspan class=\u0022inline-linked-media-wrapper\u0022\u003E\u003Cspan id=\u0022DC3\u0022 class=\u0022inline-linked-media\u0022\u003E\u003Ca href=\u0022https:\/\/www.biorxiv.org\/content\/biorxiv\/early\/2024\/11\/13\/2023.03.16.532874\/DC3\/embed\/media-3.xlsx?download=true\u0022 class=\u0022\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003E\u003Cspan class=\u0022icon-download-alt\u0022\u003E\u003C\/span\u003E[supplements\/532874_file07.xlsx]\u003C\/a\u003E\u003C\/span\u003E\u003C\/span\u003E\u003Cspan class=\u0022highwire-journal-article-marker-end\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cspan id=\u0022related-urls\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003C\/div\u003E\u003C\/div\u003E \u003C\/div\u003E\n\n \n \u003C\/div\u003E\n\u003C\/div\u003E\n \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E"}