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microspheres</title> <meta name="description" content="Search results for: porous microspheres"> <meta name="keywords" content="porous microspheres"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="porous microspheres"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 730</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: porous microspheres</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">730</span> One-Step Synthesis of Titanium Dioxide Porous Microspheres by Picosecond Pulsed Laser Welding</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Huiwu%20Yu">Huiwu Yu</a>, <a href="https://publications.waset.org/abstracts/search?q=Xiangyou%20Li"> Xiangyou Li</a>, <a href="https://publications.waset.org/abstracts/search?q=Xiaoyan%20Zeng"> Xiaoyan Zeng</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Porous spheres have been widely used in many fields due to their attractive features. In this work, an approach for fabricating porous spheres of nanoparticles was presented, in which the nanoparticles were welded together to form micro spheres by simply irradiating the nanoparticles in liquid medium by a picosecond laser. As an example, anatase titanium dioxide was chosen as a typical material on account of its metastability. The structure and morphologies of the products were characterised by X-ray diffraction (XRD), scanning electron microscope (SEM), Raman, and high-resolution transmission electron microscopy (HRTEM), respectively. The results showed that, anatase titanium dioxide micro spheres (2-10 μm) with macroporous (10-100 nm) were prepared from nano-anatase titanium dioxide nanoparticles (10-100 nm). The formation process of polycrystalline anatase titanium dioxide microspheres was investigated with different liquid mediums and the input laser fluences. Thus, this facile laser irradiation approach might provide a way for the fabrication of porous microspheres without phase-transition. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=titanium%20dioxide" title="titanium dioxide">titanium dioxide</a>, <a href="https://publications.waset.org/abstracts/search?q=porous%20microspheres" title=" porous microspheres"> porous microspheres</a>, <a href="https://publications.waset.org/abstracts/search?q=picosecond%20laser" title=" picosecond laser"> picosecond laser</a>, <a href="https://publications.waset.org/abstracts/search?q=nano-welding" title=" nano-welding"> nano-welding</a> </p> <a href="https://publications.waset.org/abstracts/61694/one-step-synthesis-of-titanium-dioxide-porous-microspheres-by-picosecond-pulsed-laser-welding" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/61694.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">305</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">729</span> The Studies of the Sorption Capabilities of the Porous Microspheres with Lignin</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20Goliszek">M. Goliszek</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Sobiesiak"> M. Sobiesiak</a>, <a href="https://publications.waset.org/abstracts/search?q=O.%20Sevastyanova"> O. Sevastyanova</a>, <a href="https://publications.waset.org/abstracts/search?q=B.%20Podkoscielna"> B. Podkoscielna</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Lignin is one of three main constituents of biomass together with cellulose and hemicellulose. It is a complex biopolymer, which contains a large number of functional groups, including aliphatic and aromatic hydroxyl groups, carbohylic groups and methoxy groups in its structure, that is why it shows potential capacities for process of sorption. Lignin is a highly cross-linked polymer with a three-dimentional structure which can provide large surface area and pore volumes. It can also posses better dispersion, diffusion and mass transfer behavior in a field of the removal of, e.g., heavy-metal-ions or aromatic pollutions. In this work emulsion-suspension copolymerization method, to synthesize the porous microspheres of divinylbenzene (DVB), styrene (St) and lignin was used. There are also microspheres without the addition of lignin for comparison. Before the copolymerization, modification lignin with methacryloyl chloride, to improve its reactivity with other monomers was done. The physico-chemical properties of the obtained microspheres, e.g., pore structures (adsorption-desorption measurements), thermal properties (DSC), tendencies to swell and the actual shapes were also studied. Due to well-developed porous structure and the presence of functional groups our materials may have great potential in sorption processes. To estimate the sorption capabilities of the microspheres towards phenol and its chlorinated derivatives the off-line SPE (solid-phase extraction) method is going to be applied. This method has various advantages, including low-cost, easy to use and enables the rapid measurements for a large number of chemicals. The efficiency of the materials in removing phenols from aqueous solution and in desorption processes will be evaluated. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=microspheres" title="microspheres">microspheres</a>, <a href="https://publications.waset.org/abstracts/search?q=lignin" title=" lignin"> lignin</a>, <a href="https://publications.waset.org/abstracts/search?q=sorption" title=" sorption"> sorption</a>, <a href="https://publications.waset.org/abstracts/search?q=solid-phase%20extraction" title=" solid-phase extraction"> solid-phase extraction</a> </p> <a href="https://publications.waset.org/abstracts/83522/the-studies-of-the-sorption-capabilities-of-the-porous-microspheres-with-lignin" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/83522.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">183</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">728</span> Microencapsulation of Phenobarbital by Ethyl Cellulose Matrix </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=S.%20Bouameur">S. Bouameur</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Chirani"> S. Chirani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of this study was to evaluate the potential use of EthylCellulose in the preparation of microspheres as a Drug Delivery System for sustained release of phenobarbital. The microspheres were prepared by solvent evaporation technique using ethylcellulose as polymer matrix with a ratio 1:2, dichloromethane as solvent and Polyvinyl alcohol 1% as processing medium to solidify the microspheres. Size, shape, drug loading capacity and entrapement efficiency were studied. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=phenobarbital" title="phenobarbital">phenobarbital</a>, <a href="https://publications.waset.org/abstracts/search?q=microspheres" title=" microspheres"> microspheres</a>, <a href="https://publications.waset.org/abstracts/search?q=ethylcellulose" title=" ethylcellulose"> ethylcellulose</a>, <a href="https://publications.waset.org/abstracts/search?q=polyvinylacohol" title=" polyvinylacohol"> polyvinylacohol</a> </p> <a href="https://publications.waset.org/abstracts/21837/microencapsulation-of-phenobarbital-by-ethyl-cellulose-matrix" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21837.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">361</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">727</span> Polymeric Microspheres for Bone Tissue Engineering</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yamina%20Boukari">Yamina Boukari</a>, <a href="https://publications.waset.org/abstracts/search?q=Nashiru%20Billa"> Nashiru Billa</a>, <a href="https://publications.waset.org/abstracts/search?q=Andrew%20Morris"> Andrew Morris</a>, <a href="https://publications.waset.org/abstracts/search?q=Stephen%20Doughty"> Stephen Doughty</a>, <a href="https://publications.waset.org/abstracts/search?q=Kevin%20Shakesheff"> Kevin Shakesheff</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Poly (lactic-co-glycolic) acid (PLGA) is a synthetic polymer that can be used in bone tissue engineering with the aim of creating a scaffold in order to support the growth of cells. The formation of microspheres from this polymer is an attractive strategy that would allow for the development of an injectable system, hence avoiding invasive surgical procedures. The aim of this study was to develop a microsphere delivery system for use as an injectable scaffold in bone tissue engineering and evaluate various formulation parameters on its properties. Porous and lysozyme-containing PLGA microspheres were prepared using the double emulsion solvent evaporation method from various molecular weights (MW). Scaffolds were formed by sintering to contain 1 -3mg of lysozyme per gram of scaffold. The mechanical and physical properties of the scaffolds were assessed along with the release of lysozyme, which was used as a model protein. The MW of PLGA was found to have an influence on microsphere size during fabrication, with increased MW leading to an increased microsphere diameter. An inversely proportional relationship was displayed between PLGA MW and mechanical strength of formed scaffolds across loadings for low, intermediate and high MW respectively. Lysozyme release from both microspheres and formed scaffolds showed an initial burst release phase, with both microspheres and scaffolds fabricated using high MW PLGA showing the lowest protein release. Following the initial burst phase, the profiles for each MW followed a similar slow release over 30 days. Overall, the results of this study demonstrate that lysozyme can be successfully incorporated into porous PLGA scaffolds and released over 30 days in vitro, and that varying the MW of the PLGA can be used as a method of altering the physical properties of the resulting scaffolds. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone" title="bone">bone</a>, <a href="https://publications.waset.org/abstracts/search?q=microspheres" title=" microspheres"> microspheres</a>, <a href="https://publications.waset.org/abstracts/search?q=PLGA" title=" PLGA"> PLGA</a>, <a href="https://publications.waset.org/abstracts/search?q=tissue%20engineering" title=" tissue engineering"> tissue engineering</a> </p> <a href="https://publications.waset.org/abstracts/24045/polymeric-microspheres-for-bone-tissue-engineering" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/24045.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">425</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">726</span> Self-Healing Hydrogel Triggered by Magnetic Microspheres to Control Glutathione Release for Cartilage Repair</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=I-Yun%20Cheng">I-Yun Cheng</a>, <a href="https://publications.waset.org/abstracts/search?q=Min-Yu%20Chiang"> Min-Yu Chiang</a>, <a href="https://publications.waset.org/abstracts/search?q=Shwu-Jen%20Chang"> Shwu-Jen Chang</a>, <a href="https://publications.waset.org/abstracts/search?q=San-Yuan%20Chen"> San-Yuan Chen</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Osteoarthritis (OA) is among the most challenging joint diseases, and as far as we know, there is currently no exact and effective cure for it because it has low self-repair ability due to lack of blood vessels and low cell density in articular cartilage. So far, there have been several methods developed to treat cartilage disorder. The most common method is to treat the high molecular weight of hyaluronic acid (HA) injection, but it will degrade after a period of time, so the patients need to inject HA repeatedly. In recent years, self-healing hydrogel has drawn considerable attention because it can recover its initial mechanical properties after damaged and further increase the lifetime of the hydrogel. Here, we aim to develop a self-healable composite hydrogel combined with magnetic microspheres to trigger glutathione(GSH) release for promoting cartilage repair. We use HA-cyclodextrin (CD) as host polymer and poly(acrylic acid)-ferrocene (pAA-Fc) as guest polymer to form the self-healable HA-pAA hydrogel by host and guest interaction where various graft amount of pAA-Fc (pAA:Fc= 1:2, 1:1.5, 1:1, 2:1, 4:1) was conducted to develop different mechanical strength hydrogel. The rheology analysis showed that the 4:1 of pAA-Fc has higher mechanical strength than other formulations. On the other hand, iron oxide nanoparticle, poly(lactic-co-glycolic acid) (PLGA) and polyethyleneimine (PEI) were used to synthesize porous magnetic microspheres via double emulsification water-in-oil-in-water (W/O/W) to increase GSH loading which acted as a reductant to control the hydrogel crosslink density and promote hydrogel self-healing. The results show that the porous magnetic microspheres can be loaded with 70% of GSH and sustained release about 50% of GSH after 24 hours. More importantly, the HA-pAA composite hydrogel can self-heal rapidly within 24 hours when suffering external force destruction by releasing GSH from the magnetic microspheres. Therefore, the developed the HA-pAA composite hydrogel combined with GSH-loaded magnetic microspheres can be in-vivo guided to damaged OA surface for inducing the cartilage repair by controlling the crosslinking of self-healing hydrogel via GSH release. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=articular%20cartilage" title="articular cartilage">articular cartilage</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20microsphere" title=" magnetic microsphere"> magnetic microsphere</a>, <a href="https://publications.waset.org/abstracts/search?q=osteoarthritis" title=" osteoarthritis"> osteoarthritis</a>, <a href="https://publications.waset.org/abstracts/search?q=self-healing%20hydrogel" title=" self-healing hydrogel"> self-healing hydrogel</a> </p> <a href="https://publications.waset.org/abstracts/106078/self-healing-hydrogel-triggered-by-magnetic-microspheres-to-control-glutathione-release-for-cartilage-repair" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/106078.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">132</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">725</span> The Influence of Alginate Microspheres Modified with DAT on the Proliferation and Adipogenic Differentiation of ASCs</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shin-Yi%20Mao">Shin-Yi Mao</a>, <a href="https://publications.waset.org/abstracts/search?q=Jiashing%20Yu"> Jiashing Yu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Decellularized adipose tissue (DAT) has received lots of attention as biological scaffolds recently. DAT that extracted from the extracellular matrix (ECM) of adipose tissues holds great promise as a xenogeneic biomaterial for tissue engineering and regenerative medicine. In our study, 2-D DATsol film was fabricated to enhance cell adhesion, proliferation, and differentiation of ASCs in vitro. DAT was also used to modify alginate for improvement of cell adhesion. Alginate microspheres modified with DAT were prepared by Nisco. These microspheres could provide a highly supportive 3-D environment for ASCs. In our works, ASCs were immobilized in alginate microspheres modified with DAT to promoted cell adhesion and adipogenic differentiation. Accordingly, we hypothesize that tissue regeneration in vivo could be promoted with the aid of modified microspheres in future. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=adipose%20stem%20cells" title="adipose stem cells">adipose stem cells</a>, <a href="https://publications.waset.org/abstracts/search?q=decellularize%20adipose%20tissue" title=" decellularize adipose tissue"> decellularize adipose tissue</a>, <a href="https://publications.waset.org/abstracts/search?q=Alginate" title=" Alginate"> Alginate</a>, <a href="https://publications.waset.org/abstracts/search?q=microcarries" title=" microcarries"> microcarries</a> </p> <a href="https://publications.waset.org/abstracts/13276/the-influence-of-alginate-microspheres-modified-with-dat-on-the-proliferation-and-adipogenic-differentiation-of-ascs" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/13276.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">444</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">724</span> Preparation and in vitro Characterisation of Chitosan/Hydroxyapatite Injectable Microspheres as Hard Tissue Substitution</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=H.%20Maachou">H. Maachou</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Chagnes"> A. Chagnes</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20Cote"> G. Cote </a> </p> <p class="card-text"><strong>Abstract:</strong></p> The present work reports the properties of chitosan/hydroxyapatite (Cs/HA: 100/00, 70/30 and 30/70) composite microspheres obtained by emulsification processing route. The morphology of chitosane microspheres was observed by a scanning electron microscope (SEM) which shows an aggregate of spherical microspheres with a particle size, determined by optical microscope, ranged from 4 to 10 µm. Thereafter, a biomimetic approach was used to study the in vitro biomineralization of these composites. It concerns the composites immersion in simulated body fluid (SBF) for different times. The deposited calcium phosphate was studied using X-ray diffraction analysis (XRD), FTIR spectroscopy and ICP analysis of phosphorus. In fact, the mineral formed on Cs/HA microspheres was a mixture of carbonated HA and β-TCP as showed by FTIR peaks at 1419,5 and 871,8 cm-1 and XRD peak at 29,5°. This formation was induced by the presence of HA in chitosan microspheres. These results are confirmed by SEM micrographs which chow the Ca-P crystals growth in form of cauliflowers. So, these materials are of great interest for bone regeneration applications due to their ability to nucleate calcium phosphates in presence of simulated body fluid (SBF). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title="hydroxyapatite">hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=chitosan" title=" chitosan"> chitosan</a>, <a href="https://publications.waset.org/abstracts/search?q=microsphere" title=" microsphere"> microsphere</a>, <a href="https://publications.waset.org/abstracts/search?q=composite" title=" composite"> composite</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20regeneration" title=" bone regeneration"> bone regeneration</a> </p> <a href="https://publications.waset.org/abstracts/12735/preparation-and-in-vitro-characterisation-of-chitosanhydroxyapatite-injectable-microspheres-as-hard-tissue-substitution" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/12735.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">330</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">723</span> Formulation and Evaluation of Lisinopril Microspheres for Nasal Delivery</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=S.%20S.%20Patil">S. S. Patil</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20M.%20Mhetre"> R. M. Mhetre</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20V.%20Patil"> S. V. Patil </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Lisinopril is an angiotensin converting enzyme inhibitor used in the treatment of hypertension and heart failure in prophylactic treatment after myocardial infarction and in diabetic nephropathy. However, it is very poorly absorbed from gastro-intestinal tract. Intranasal administration is an ideal alternative to the parenteral route for systemic drug delivery. Formulating multiparticulate system with mucoadhesive polymers provide a significant increase in the nasal residence time. The aim of the present approach was to overcome the drawbacks of the conventional dosage forms of lisinopril by formulating intranasal microspheres with Carbopol 974P NF and HPMC K4 M along with film forming polymer ethyl cellulose.The microspheres were prepared by emulsion solvent evaporation method. The prepared microspheres were characterized for encapsulation efficiency, drug loading, particle size, and surface morphology, degree of swelling, ex vivo mucoadhesion, drug release, ex vivo diffusion studies. All formulations has shown entrapment efficiency between 80 to more than 95%, mucoadhesion was more than 80 % and drug release up to 90 %. Ex vivo studies revealed tht the improved bioavailability of drug compared to oral drug administration. Both in vitro and in vivo studies conclude that combination of Carbopol and HPMC based microspheres shown better results than single carbopol based microspheres for the delivery of lisinopril. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=microspheres" title="microspheres">microspheres</a>, <a href="https://publications.waset.org/abstracts/search?q=lisinopril" title=" lisinopril"> lisinopril</a>, <a href="https://publications.waset.org/abstracts/search?q=nasal%20delivery" title=" nasal delivery"> nasal delivery</a>, <a href="https://publications.waset.org/abstracts/search?q=solvent%20evaporation%20method" title=" solvent evaporation method"> solvent evaporation method</a> </p> <a href="https://publications.waset.org/abstracts/22193/formulation-and-evaluation-of-lisinopril-microspheres-for-nasal-delivery" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/22193.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">528</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">722</span> Development, Optimization and Characterization of Gastroretentive Multiparticulate Drug Delivery System</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Swapnila%20V.%20Vanshiv">Swapnila V. Vanshiv</a>, <a href="https://publications.waset.org/abstracts/search?q=Hemant%20P.%20Joshi"> Hemant P. Joshi</a>, <a href="https://publications.waset.org/abstracts/search?q=Atul%20B.%20Aware"> Atul B. Aware</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Current study illustrates the formulation of floating microspheres for purpose of gastroretention of Dipyridamole which shows pH dependent solubility, with the highest solubility in acidic pH. The formulation involved hollow microsphere preparation by using solvent evaporation technique. Concentrations of rate controlling polymer, hydrophilic polymer, internal phase ratio, stirring speed were optimized to get desired responses, namely release of Dipyridamole, buoyancy of microspheres, entrapment efficiency of microspheres. In the formulation, the floating microspheres were prepared by using ethyl cellulose as release retardant and HPMC as a low density hydrophilic swellable polymer. Formulated microspheres were evaluated for their physical properties such as particle size and surface morphology by optical microscopy and SEM. Entrapment efficiency, floating behavior and drug release study as well the formulation was evaluated for in vivo gastroretention in rabbits using gamma scintigraphy. Formulation showed 75% drug release up to 10 hr with entrapment efficiency of 91% and 88% buoyancy till 10 hr. Gamma scintigraphic studies revealed that the optimized system was retained in the gastric region (stomach) for a prolonged period i.e. more than 5 hr. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Dipyridamole%20microspheres" title="Dipyridamole microspheres">Dipyridamole microspheres</a>, <a href="https://publications.waset.org/abstracts/search?q=gastroretention" title=" gastroretention"> gastroretention</a>, <a href="https://publications.waset.org/abstracts/search?q=HPMC" title=" HPMC"> HPMC</a>, <a href="https://publications.waset.org/abstracts/search?q=optimization%20method" title=" optimization method"> optimization method</a> </p> <a href="https://publications.waset.org/abstracts/8657/development-optimization-and-characterization-of-gastroretentive-multiparticulate-drug-delivery-system" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/8657.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">385</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">721</span> Numerical Simulation of Production of Microspheres from Polymer Emulsion in Microfluidic Device toward Using in Drug Delivery Systems</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nizar%20Jawad%20Hadi">Nizar Jawad Hadi</a>, <a href="https://publications.waset.org/abstracts/search?q=Sajad%20Abd%20Alabbas"> Sajad Abd Alabbas</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Because of their ability to encapsulate and release drugs in a controlled manner, microspheres fabricated from polymer emulsions using microfluidic devices have shown promise for drug delivery applications. In this study, the effects of velocity, density, viscosity, and surface tension, as well as channel diameter, on microsphere generation were investigated using Fluent Ansys software. The software was programmed with the physical properties of the polymer emulsion such as density, viscosity and surface tension. Simulation will then be performed to predict fluid flow and microsphere production and improve the design of drug delivery applications based on changes in these parameters. The effects of capillary and Weber numbers are also studied. The results of the study showed that the size of the microspheres can be controlled by adjusting the speed and diameter of the channel. Narrower microspheres resulted from narrower channel widths and higher flow rates, which could improve drug delivery efficiency, while smaller microspheres resulted from lower interfacial surface tension. The viscosity and density of the polymer emulsion significantly affected the size of the microspheres, ith higher viscosities and densities producing smaller microspheres. The loading and drug release properties of the microspheres created with the microfluidic technique were also predicted. The results showed that the microspheres can efficiently encapsulate drugs and release them in a controlled manner over a period of time. This is due to the high surface area to volume ratio of the microspheres, which allows for efficient drug diffusion. The ability to tune the manufacturing process using factors such as speed, density, viscosity, channel diameter, and surface tension offers a potential opportunity to design drug delivery systems with greater efficiency and fewer side effects. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=polymer%20emulsion" title="polymer emulsion">polymer emulsion</a>, <a href="https://publications.waset.org/abstracts/search?q=microspheres" title=" microspheres"> microspheres</a>, <a href="https://publications.waset.org/abstracts/search?q=numerical%20simulation" title=" numerical simulation"> numerical simulation</a>, <a href="https://publications.waset.org/abstracts/search?q=microfluidic%20device" title=" microfluidic device"> microfluidic device</a> </p> <a href="https://publications.waset.org/abstracts/170799/numerical-simulation-of-production-of-microspheres-from-polymer-emulsion-in-microfluidic-device-toward-using-in-drug-delivery-systems" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/170799.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">64</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">720</span> Mesoporous Tussah Silk Fibroin Microspheres for Drug Delivery</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Weitao%20Zhou">Weitao Zhou</a>, <a href="https://publications.waset.org/abstracts/search?q=Qing%20Wang"> Qing Wang</a>, <a href="https://publications.waset.org/abstracts/search?q=Jianxin%20He"> Jianxin He</a>, <a href="https://publications.waset.org/abstracts/search?q=Shizhong%20Cui"> Shizhong Cui</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Mesoporous Tussah silk fibroin (TSF) spheres were fabricated via the self-assembly of TSF molecules in aqueous solutions. The results showed that TSF particles were approximately three-dimensional spheres with the diameter ranging from 500nm to 6μm without adherence. More importantly, the surface morphology is mesoporous structure with nano-pores of 20nm - 200nm in size. Fourier transform infrared (FT-IR) and X-ray diffraction (XRD) studies demonstrated that mesoporous TSF spheres mainly contained beta-sheet conformation (44.1 %) as well as slight amounts of random coil (13.2 %). Drug release test was performed with 5-fluorouracil (5-Fu) as a model drug and the result indicated the mesoporous TSF microspheres had a good capacity of sustained drug release. It is expected that these stable and high-crystallinity mesoporous TSF sphere produced without organic solvents, which have significantly improved drug release properties, is a very promising material for controlled gene medicines delivery. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Tussah%20silk%20fibroin" title="Tussah silk fibroin">Tussah silk fibroin</a>, <a href="https://publications.waset.org/abstracts/search?q=porous%20materials" title=" porous materials"> porous materials</a>, <a href="https://publications.waset.org/abstracts/search?q=microsphere" title=" microsphere"> microsphere</a>, <a href="https://publications.waset.org/abstracts/search?q=drug%20release" title=" drug release"> drug release</a> </p> <a href="https://publications.waset.org/abstracts/69674/mesoporous-tussah-silk-fibroin-microspheres-for-drug-delivery" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/69674.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">459</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">719</span> Management and Evaluation of the Importance of Porous Media in Biomedical Engineering as Associated with Magnetic Resonance Imaging Besides Drug Delivery</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Fateme%20Nokhodchi%20Bonab">Fateme Nokhodchi Bonab</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Studies related to magnetic resonance imaging (MRI) and drug delivery are reviewed in this study to demonstrate the role of transport theory in porous media in facilitating advances in biomedical applications. Diffusion processes are believed to be important in many therapeutic modalities such as: B. Delivery of drugs to the brain. We analyse the progress in the development of diffusion equations using the local volume average method and the evaluation of applications related to diffusion equations. Torsion and porosity have significant effects on diffusive transport. In this study, various relevant models of torsion are presented and mathematical modeling of drug release from biodegradable delivery systems is analysed. In this study, a new model of drug release kinetics from porous biodegradable polymeric microspheres under bulk and surface erosion of the polymer matrix is presented. Solute drug diffusion, drug dissolution from the solid phase, and polymer matrix erosion have been found to play a central role in controlling the overall drug release process. This work paves the way for MRI and drug delivery researchers to develop comprehensive models based on porous media theory that use fewer assumptions compared to other approaches. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=MRI" title="MRI">MRI</a>, <a href="https://publications.waset.org/abstracts/search?q=porous%20media" title=" porous media"> porous media</a>, <a href="https://publications.waset.org/abstracts/search?q=drug%20delivery" title=" drug delivery"> drug delivery</a>, <a href="https://publications.waset.org/abstracts/search?q=biomedical%20applications" title=" biomedical applications"> biomedical applications</a> </p> <a href="https://publications.waset.org/abstracts/158833/management-and-evaluation-of-the-importance-of-porous-media-in-biomedical-engineering-as-associated-with-magnetic-resonance-imaging-besides-drug-delivery" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/158833.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">89</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">718</span> Development and In vitro Characterization of Diclofenac-Loaded Microparticles</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Prakriti%20Diwan">Prakriti Diwan</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Saraf"> S. Saraf</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The present study involves preparation and evaluation of microparticles of diclofenac sodium. The microparticles were prepared by the emulsion solvent evaporation techniques using ethylcellulose polymer. Four different batches of microspheres were prepared by varying the concentration of polymer from 50% to 80% w/w. The microspheres were characterized for drug content, percentage yield and encapsulation efficiency, particle size analysis and surface morphology. Microsphere prepared with high drug content produces higher percentage yield and encapsulation efficiency values. It was observed the increase in concentration of the polymer, increases the mean particle size of the microspheres. The effect of polymer concentration on the in vitro release of diclofenac from the microspheres was also studied. The production microparticles yield showed 98.74%, mean particle size 956.32µm and loading efficiency 97.15%. The results were found that microparticles prepared had slower release than microparticles (p>0.05). Therefore, it may be concluded that drug loaded microparticles are suitable delivery systems for diclofenac sodium. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=diclofenac%20sodium" title="diclofenac sodium">diclofenac sodium</a>, <a href="https://publications.waset.org/abstracts/search?q=emulsion%20solvent%20evaporation" title=" emulsion solvent evaporation"> emulsion solvent evaporation</a>, <a href="https://publications.waset.org/abstracts/search?q=ethylcellulose" title=" ethylcellulose"> ethylcellulose</a>, <a href="https://publications.waset.org/abstracts/search?q=microparticles" title=" microparticles"> microparticles</a> </p> <a href="https://publications.waset.org/abstracts/47663/development-and-in-vitro-characterization-of-diclofenac-loaded-microparticles" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/47663.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">287</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">717</span> Performance Evaluation and Plugging Characteristics of Controllable Self-Aggregating Colloidal Particle Profile Control Agent </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Zhiguo%20Yang">Zhiguo Yang</a>, <a href="https://publications.waset.org/abstracts/search?q=Xiangan%20Yue"> Xiangan Yue</a>, <a href="https://publications.waset.org/abstracts/search?q=Minglu%20Shao"> Minglu Shao</a>, <a href="https://publications.waset.org/abstracts/search?q=Yue%20Yang"> Yue Yang</a>, <a href="https://publications.waset.org/abstracts/search?q=Rongjie%20Yan"> Rongjie Yan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> It is difficult to realize deep profile control because of the small pore-throats and easy water channeling in low-permeability heterogeneous reservoir, and the traditional polymer microspheres have the contradiction between injection and plugging. In order to solve this contradiction, the controllable self-aggregating colloidal particles (CSA) containing amide groups on the surface of microspheres was prepared based on emulsion polymerization of styrene and acrylamide. The dispersed solution of CSA colloidal particles, whose particle size is much smaller than the diameter of pore-throats, was injected into the reservoir. When the microspheres migrated to the deep part of reservoir, , these CSA colloidal particles could automatically self-aggregate into large particle clusters under the action of the shielding agent and the control agent, so as to realize the plugging of the water channels. In this paper, the morphology, temperature resistance and self-aggregation properties of CSA microspheres were studied by transmission electron microscopy (TEM) and bottle test. The results showed that CSA microspheres exhibited heterogeneous core-shell structure, good dispersion, and outstanding thermal stability. The microspheres remain regular and uniform spheres at 100℃ after aging for 35 days. With the increase of the concentration of the cations, the self-aggregation time of CSA was gradually shortened, and the influence of bivalent cations was greater than that of monovalent cations. Core flooding experiments showed that CSA polymer microspheres have good injection properties, CSA particle clusters can effective plug the water channels and migrate to the deep part of the reservoir for profile control. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=heterogeneous%20reservoir" title="heterogeneous reservoir">heterogeneous reservoir</a>, <a href="https://publications.waset.org/abstracts/search?q=deep%20profile%20control" title=" deep profile control"> deep profile control</a>, <a href="https://publications.waset.org/abstracts/search?q=emulsion%20polymerization" title=" emulsion polymerization"> emulsion polymerization</a>, <a href="https://publications.waset.org/abstracts/search?q=colloidal%20particles" title=" colloidal particles"> colloidal particles</a>, <a href="https://publications.waset.org/abstracts/search?q=plugging%20characteristic" title=" plugging characteristic"> plugging characteristic</a> </p> <a href="https://publications.waset.org/abstracts/134409/performance-evaluation-and-plugging-characteristics-of-controllable-self-aggregating-colloidal-particle-profile-control-agent" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/134409.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">241</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">716</span> Hydrogel Hybridizing Temperature-Cured Dissolvable Gelatin Microspheres as Non-Anchorage Dependent Cell Carriers for Tissue Engineering Applications</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Dong-An%20Wang">Dong-An Wang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> All kinds of microspheres have been extensively employed as carriers for drug, gene and therapeutic cell delivery. Most therapeutic cell delivery microspheres rely on a two-step methodology: fabrication of microspheres and subsequent seeding of cells onto them. In this study, we have developed a novel one-step cell encapsulation technique using a convenient and instant water-in-oil single emulsion approach to form cell-encapsulated gelatin microspheres. This technology is adopted for hyaline cartilage tissue engineering, in which autologous chondrocytes are used as therapeutic cells. Cell viability was maintained throughout and after the microsphere formation (75-100 µm diameters) process that avoids involvement of any covalent bonding reactions or exposure to any further chemicals. Further encapsulation of cell-laden microspheres in alginate gels were performed under 4°C via a prompt process. Upon the formation of alginate constructs, they were immediately relocated into CO2 incubator where the temperature was maintained at 37°C; under this temperature, the cell-laden gelatin microspheres dissolved within hours to yield similarly sized cavities and the chondrocytes were therefore suspended within the cavities inside the alginate gel bulk. Hence, the gelatin cell-laden microspheres served two roles: as cell delivery vehicles which can be removable through temperature curing, and as porogens within an alginate hydrogel construct to provide living space for cell growth and tissue development as well as better permeability for mutual diffusions. These cell-laden microspheres, namely “temperature-cured dissolvable gelatin microsphere based cell carriers” (tDGMCs), were further encapsulated in a chondrocyte-laden alginate scaffold system and analyzed by WST-1, gene expression analyses, biochemical assays, histology and immunochemistry stains. The positive results consistently demonstrated the promise of tDGMC technology in delivering these non-anchorage dependent cells (chondrocytes). It can be further conveniently translated into delivery of other non-anchorage dependent cell species, including stem cells, progenitors or iPS cells, for regeneration of tissues in internal organs, such as engineered hepatogenesis or pancreatic regeneration. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biomaterials" title="biomaterials">biomaterials</a>, <a href="https://publications.waset.org/abstracts/search?q=tissue%20engineering" title=" tissue engineering"> tissue engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=microsphere" title=" microsphere"> microsphere</a>, <a href="https://publications.waset.org/abstracts/search?q=hydrogel" title=" hydrogel"> hydrogel</a>, <a href="https://publications.waset.org/abstracts/search?q=porogen" title=" porogen"> porogen</a>, <a href="https://publications.waset.org/abstracts/search?q=anchorage%20dependence" title=" anchorage dependence"> anchorage dependence</a> </p> <a href="https://publications.waset.org/abstracts/4056/hydrogel-hybridizing-temperature-cured-dissolvable-gelatin-microspheres-as-non-anchorage-dependent-cell-carriers-for-tissue-engineering-applications" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/4056.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">396</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">715</span> Everolimus Loaded Polyvinyl Alcohol Microspheres for Sustained Drug Delivery in the Treatment of Subependymal Giant Cell Astrocytoma</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Lynn%20Louis">Lynn Louis</a>, <a href="https://publications.waset.org/abstracts/search?q=Bor%20Shin%20Chee"> Bor Shin Chee</a>, <a href="https://publications.waset.org/abstracts/search?q=Marion%20McAfee"> Marion McAfee</a>, <a href="https://publications.waset.org/abstracts/search?q=Michael%20Nugent"> Michael Nugent</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This article aims to develop a sustained release formulation of microspheres containing the mTOR inhibitor Everolimus (EVR) using Polyvinyl alcohol (PVA) to enhance the bioavailability of the drug and to overcome poor solubility characteristics of Everolimus. This paper builds on recent work in the manufacture of microspheres using the sessile droplet technique by freezing the polymer-drug solution by suspending the droplets into pre-cooled ethanol vials immersed in liquid nitrogen. The spheres were subjected to 6 freezing cycles and 3 freezing cycles with thawing to obtain proper geometry, prevent aggregation, and achieve physical cross-linking. The prepared microspheres were characterised for surface morphology by SEM, where a 3-D porous structure was observed. The in vitro release studies showed a 62.17% release over 12.5 days, indicating a sustained release due to good encapsulation. This result is comparatively much more than the 49.06% release achieved within 4 hours from the solvent cast Everolimus film as a control with no freeze-thaw cycles performed. The solvent cast films were made in this work for comparison. A prolonged release of Everolimus using a polymer-based drug delivery system is essential to reach optimal therapeutic concentrations in treating SEGA tumours without systemic exposure. These results suggest that the combination of PVA and Everolimus via a rheological synergism enhanced the bioavailability of the hydrophobic drug Everolimus. Physical-chemical characterisation using DSC and FTIR analysis showed compatibility of the drug with the polymer, and the stability of the drug was maintained owing to the high molecular weight of the PVA. The obtained results indicate that the developed PVA/EVR microsphere is highly suitable as a potential drug delivery system with improved bioavailability in treating Subependymal Giant cell astrocytoma (SEGA). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=drug%20delivery%20system" title="drug delivery system">drug delivery system</a>, <a href="https://publications.waset.org/abstracts/search?q=everolimus" title=" everolimus"> everolimus</a>, <a href="https://publications.waset.org/abstracts/search?q=freeze-thaw%20cycles" title=" freeze-thaw cycles"> freeze-thaw cycles</a>, <a href="https://publications.waset.org/abstracts/search?q=polyvinyl%20alcohol" title=" polyvinyl alcohol"> polyvinyl alcohol</a> </p> <a href="https://publications.waset.org/abstracts/151445/everolimus-loaded-polyvinyl-alcohol-microspheres-for-sustained-drug-delivery-in-the-treatment-of-subependymal-giant-cell-astrocytoma" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/151445.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">127</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">714</span> Preparation of Porous Metal Membrane by Thermal Annealing for Thin Film Encapsulation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jaibir%20Sharma">Jaibir Sharma</a>, <a href="https://publications.waset.org/abstracts/search?q=Lee%20JaeWung"> Lee JaeWung</a>, <a href="https://publications.waset.org/abstracts/search?q=Merugu%20Srinivas"> Merugu Srinivas</a>, <a href="https://publications.waset.org/abstracts/search?q=Navab%20Singh"> Navab Singh </a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper presents thermal annealing dewetting technique for the preparation of porous metal membrane for thin film encapsulation application. Thermal annealing dewetting experimental results reveal that pore size in porous metal membrane depend upon i.e. 1. The substrate on which metal is deposited for formation of porous metal cap membrane, 2. Melting point of metal used for porous metal cap layer membrane formation, 3. Thickness of metal used for cap layer, 4. Temperature used for porous metal membrane formation. Silver (Ag) was used as a metal for preparation of porous metal membrane by annealing the film at different temperature. Pores in porous silver film were analyzed using Scanning Electron Microscope (SEM). In order to check the usefulness of porous metal film for thin film encapsulation application, the porous silver film prepared on amorphous silicon (a-Si) was release using XeF2. Finally, guide line and structures are suggested to use this porous membrane for thin film encapsulation (TFE) application. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=dewetting" title="dewetting">dewetting</a>, <a href="https://publications.waset.org/abstracts/search?q=themal%20annealing" title=" themal annealing"> themal annealing</a>, <a href="https://publications.waset.org/abstracts/search?q=metal" title=" metal"> metal</a>, <a href="https://publications.waset.org/abstracts/search?q=melting%20point" title=" melting point"> melting point</a>, <a href="https://publications.waset.org/abstracts/search?q=porous" title=" porous"> porous</a> </p> <a href="https://publications.waset.org/abstracts/31602/preparation-of-porous-metal-membrane-by-thermal-annealing-for-thin-film-encapsulation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/31602.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">657</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">713</span> Response Surface Methodology to Obtain Disopyramide Phosphate Loaded Controlled Release Ethyl Cellulose Microspheres</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Krutika%20K.%20Sawant">Krutika K. Sawant</a>, <a href="https://publications.waset.org/abstracts/search?q=Anil%20Solanki"> Anil Solanki </a> </p> <p class="card-text"><strong>Abstract:</strong></p> The present study deals with the preparation and optimization of ethyl cellulose-containing disopyramide phosphate loaded microspheres using solvent evaporation technique. A central composite design consisting of a two-level full factorial design superimposed on a star design was employed for optimizing the preparation microspheres. The drug:polymer ratio (X1) and speed of the stirrer (X2) were chosen as the independent variables. The cumulative release of the drug at a different time (2, 6, 10, 14, and 18 hr) was selected as the dependent variable. An optimum polynomial equation was generated for the prediction of the response variable at time 10 hr. Based on the results of multiple linear regression analysis and F statistics, it was concluded that sustained action can be obtained when X1 and X2 are kept at high levels. The X1X2 interaction was found to be statistically significant. The drug release pattern fitted the Higuchi model well. The data of a selected batch were subjected to an optimization study using Box-Behnken design, and an optimal formulation was fabricated. Good agreement was observed between the predicted and the observed dissolution profiles of the optimal formulation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=disopyramide%20phosphate" title="disopyramide phosphate">disopyramide phosphate</a>, <a href="https://publications.waset.org/abstracts/search?q=ethyl%20cellulose" title=" ethyl cellulose"> ethyl cellulose</a>, <a href="https://publications.waset.org/abstracts/search?q=microspheres" title=" microspheres"> microspheres</a>, <a href="https://publications.waset.org/abstracts/search?q=controlled%20release" title=" controlled release"> controlled release</a>, <a href="https://publications.waset.org/abstracts/search?q=Box-Behnken%20design" title=" Box-Behnken design"> Box-Behnken design</a>, <a href="https://publications.waset.org/abstracts/search?q=factorial%20design" title=" factorial design"> factorial design</a> </p> <a href="https://publications.waset.org/abstracts/21542/response-surface-methodology-to-obtain-disopyramide-phosphate-loaded-controlled-release-ethyl-cellulose-microspheres" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21542.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">457</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">712</span> Fabrication of Highly-Ordered Interconnected Porous Polymeric Particles and Structures</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Alroaithi">Mohammad Alroaithi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Porous polymeric materials have attracted a great attention due to their distinctive porous structure within a polymer matrix. They are characterised by the presence of external pores on the surface as well as inner interconnected windows. Conventional techniques to produce porous polymeric materials encounters major challenge in controlling the properties of the resultant structures including morphology, pores, cavities size, and porosity. Herein, we present a facile and versatile microfluidics technique for the fabrication of uniform porous polymeric structures with highly ordered and well-defined interconnected windows. The shapes of the porous structures can either be a microparticles or foam. Both shapes used microfluidics platform to first produce monodisperse emulsion. The uniform emulsions, were then consolidated into porous structures through UV photopolymerisation. The morphology, pores, cavities size, and porosity of the structures can be precisely manipulated by the flowrate. The proposed strategy might provide a key advantage for fabrication of uniform porous materials over many existing technologies. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=polymer" title="polymer">polymer</a>, <a href="https://publications.waset.org/abstracts/search?q=porous%20particles" title=" porous particles"> porous particles</a>, <a href="https://publications.waset.org/abstracts/search?q=microfluidics" title=" microfluidics"> microfluidics</a>, <a href="https://publications.waset.org/abstracts/search?q=porous%20structures" title=" porous structures"> porous structures</a> </p> <a href="https://publications.waset.org/abstracts/84709/fabrication-of-highly-ordered-interconnected-porous-polymeric-particles-and-structures" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/84709.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">186</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">711</span> Numerical Study of Fluid Flow and Heat Transfer in the Spongy-Porous Media</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Zeinab%20Sayed%20Abdel%20Rehim">Zeinab Sayed Abdel Rehim</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20A.%20Ziada"> M. A. Ziada</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20Salwa%20El-Deeb"> H. Salwa El-Deeb </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Numerical study of fluid flow, heat transfer and thermal energy storing or released in/from spongy-porous media to predict the thermal performance and characteristics of the porous media as packed bed system is presented in this work. This system is cylindrical channel filled with porous media (carbon foam). The system consists of working fluid (air) and spongy-porous medium; they act as the heat exchanger (heating or cooling modes) where thermal interaction occurs between the working fluid and the porous medium. The spongy-porous media are defined by the different type of porous medium employed in the storing or cooling modes. Two different porous media are considered in this study: Carbon foam, and Silicon rubber. The flow of the working fluid (air) is one dimensional in the axial direction from the top to downward and steady state conditions. The numerical results of transient temperature distribution for both working fluid and the spongy-porous medium phases and the amount of stored/realized heat inside/from the porous medium for each case with respect to the operating parameters and the spongy-porous media characteristics are illustrated. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=fluid%20flow" title="fluid flow">fluid flow</a>, <a href="https://publications.waset.org/abstracts/search?q=heat%20transfer" title=" heat transfer"> heat transfer</a>, <a href="https://publications.waset.org/abstracts/search?q=numerical%20analysis" title=" numerical analysis"> numerical analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=spongy-porous%20media" title=" spongy-porous media"> spongy-porous media</a>, <a href="https://publications.waset.org/abstracts/search?q=thermal%20performance" title=" thermal performance"> thermal performance</a>, <a href="https://publications.waset.org/abstracts/search?q=transient%20conditions" title=" transient conditions"> transient conditions</a> </p> <a href="https://publications.waset.org/abstracts/30266/numerical-study-of-fluid-flow-and-heat-transfer-in-the-spongy-porous-media" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/30266.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">545</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">710</span> Humidity Sensing Behavior of Graphene Oxide on Porous Silicon Substrate</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Amirhossein%20Hasani">Amirhossein Hasani</a>, <a href="https://publications.waset.org/abstracts/search?q=Shamin%20Houshmand%20Sharifi"> Shamin Houshmand Sharifi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this work, we investigate humidity sensing behavior of the graphene oxide with porous silicon substrate. By evaporation method, aluminum interdigital electrodes have been deposited onto porous silicon substrate. Then, by drop-casting method graphene oxide solution was deposited onto electrodes. The porous silicon was formed by electrochemical etching. The experimental results showed that using porous silicon substrate, we obtained two times larger sensitivity and response time compared with the results obtained with silicon substrate without porosity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=graphene%20oxide" title="graphene oxide">graphene oxide</a>, <a href="https://publications.waset.org/abstracts/search?q=porous%20silicon" title=" porous silicon"> porous silicon</a>, <a href="https://publications.waset.org/abstracts/search?q=humidity%20sensor" title=" humidity sensor"> humidity sensor</a>, <a href="https://publications.waset.org/abstracts/search?q=electrochemical" title=" electrochemical"> electrochemical</a> </p> <a href="https://publications.waset.org/abstracts/13093/humidity-sensing-behavior-of-graphene-oxide-on-porous-silicon-substrate" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/13093.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">605</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">709</span> Acrylic Microspheres-Based Microbial Bio-Optode for Nitrite Ion Detection </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Siti%20Nur%20Syazni%20Mohd%20Zuki">Siti Nur Syazni Mohd Zuki</a>, <a href="https://publications.waset.org/abstracts/search?q=Tan%20Ling%20Ling"> Tan Ling Ling</a>, <a href="https://publications.waset.org/abstracts/search?q=Nina%20Suhaity%20Azmi"> Nina Suhaity Azmi</a>, <a href="https://publications.waset.org/abstracts/search?q=Chong%20Kwok%20Feng"> Chong Kwok Feng</a>, <a href="https://publications.waset.org/abstracts/search?q=Lee%20Yook%20Heng"> Lee Yook Heng</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Nitrite (NO2-) ion is used prevalently as a preservative in processed meat. Elevated levels of nitrite also found in edible bird’s nests (EBNs). Consumption of NO2- ion at levels above the health-based risk may cause cancer in humans. Spectrophotometric Griess test is the simplest established standard method for NO2- ion detection, however, it requires careful control of pH of each reaction step and susceptible to strong oxidants and dyeing interferences. Other traditional methods rely on the use of laboratory-scale instruments such as GC-MS, HPLC and ion chromatography, which cannot give real-time response. Therefore, it is of signiﬁcant need for devices capable of measuring nitrite concentration in-situ, rapidly and without reagents, sample pretreatment or extraction step. Herein, we constructed a microspheres-based microbial optode for visual quantitation of NO2- ion. Raoutella planticola, the bacterium expressing NAD(P)H nitrite reductase (NiR) enzyme has been successfully extracted by microbial technique from EBN collected from local birdhouse. The whole cells and the lipophilic Nile Blue chromoionophore were physically absorbed on the photocurable poly(n-butyl acrylate-N-acryloxysuccinimide) [poly (nBA-NAS)] microspheres, whilst the reduced coenzyme NAD(P)H was covalently immobilized on the succinimide-functionalized acrylic microspheres to produce a reagentless biosensing system. Upon the NiR enzyme catalyzes the oxidation of NAD(P)H to NAD(P)+, NO2- ion is reduced to ammonium hydroxide, and that a colour change from blue to pink of the immobilized Nile Blue chromoionophore is perceived as a result of deprotonation reaction increasing the local pH in the microspheres membrane. The microspheres-based optosensor was optimized with a reflectance spectrophotometer at 639 nm and pH 8. The resulting microbial bio-optode membrane could quantify NO2- ion at 0.1 ppm and had a linear response up to 400 ppm. Due to the large surface area to mass ratio of the acrylic microspheres, it allows efficient solid state diffusional mass transfer of the substrate to the bio-recognition phase, and achieve the steady state response as fast as 5 min. The proposed optical microbial biosensor requires no sample pre-treatment step and possesses high stability as the whole cell biocatalyst provides protection to the enzymes from interfering substances, hence it is suitable for measurements in contaminated samples. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=acrylic%20microspheres" title="acrylic microspheres">acrylic microspheres</a>, <a href="https://publications.waset.org/abstracts/search?q=microbial%20bio-optode" title=" microbial bio-optode"> microbial bio-optode</a>, <a href="https://publications.waset.org/abstracts/search?q=nitrite%20ion" title=" nitrite ion"> nitrite ion</a>, <a href="https://publications.waset.org/abstracts/search?q=reflectometric" title=" reflectometric"> reflectometric</a> </p> <a href="https://publications.waset.org/abstracts/23850/acrylic-microspheres-based-microbial-bio-optode-for-nitrite-ion-detection" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/23850.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">448</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">708</span> Memristive Properties of Nanostructured Porous Silicon</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Madina%20Alimova">Madina Alimova</a>, <a href="https://publications.waset.org/abstracts/search?q=Margulan%20Ibraimov"> Margulan Ibraimov</a>, <a href="https://publications.waset.org/abstracts/search?q=Ayan%20Tileu"> Ayan Tileu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The paper describes methods for obtaining porous structures with the properties of a silicon-based memristor and explains the electrical properties of porous silicon films. Based on the results, there is a positive shift in the current-voltage characteristics (CVC) after each measurement, i.e., electrical properties depend not only on the applied voltage but also on the previous state. After 3 minutes of rest, the film returns to its original state (reset). The method for obtaining a porous silicon nanofilm with the properties of a memristor is simple and does not require additional effort. Based on the measurement results, the typical memristive behavior of the porous silicon nanofilm is analyzed. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=porous%20silicon" title="porous silicon">porous silicon</a>, <a href="https://publications.waset.org/abstracts/search?q=current-voltage%20characteristics" title=" current-voltage characteristics"> current-voltage characteristics</a>, <a href="https://publications.waset.org/abstracts/search?q=memristor" title=" memristor"> memristor</a>, <a href="https://publications.waset.org/abstracts/search?q=nanofilms" title=" nanofilms"> nanofilms</a> </p> <a href="https://publications.waset.org/abstracts/147523/memristive-properties-of-nanostructured-porous-silicon" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/147523.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">130</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">707</span> Experimental Technique to Study Colloid Deposition in Porous Media</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Abdelkader%20Djehiche">Abdelkader Djehiche</a>, <a href="https://publications.waset.org/abstracts/search?q=Mostefa%20Gafsi"> Mostefa Gafsi</a>, <a href="https://publications.waset.org/abstracts/search?q=Henri%20Bertin"> Henri Bertin</a>, <a href="https://publications.waset.org/abstracts/search?q=Aziz%20Omari"> Aziz Omari</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The flows of colloidal suspensions in porous media find many applications in fields such as Petroleum, Hydraulic engineering, deep-bed filtration. For each application, the scientific problems can be summarized the flow in porous medium of a colloidal suspension whose particles having characteristic dimension is considerable in comparison with the pores dimension. In certain cases, one can observe a deposit of particles on the surface of the pores which results in a significant modification in the physical properties of the porous medium. The objective of our study is to use a non-destructive experimental method, the attenuation of g-rays, to study the influence of the number of Peclet on the deposit of latex particles in a consolidated porous medium. The first results obtained show a good agreement between local and global measurements of the deposit of the particles in porous medium. The deposit takes place in a progressive way along the porous medium and leads to a monolayer deposit of which the average thickness is of about the size diameter of the colloidal particles. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=colloid" title="colloid">colloid</a>, <a href="https://publications.waset.org/abstracts/search?q=gamma%20ray" title=" gamma ray"> gamma ray</a>, <a href="https://publications.waset.org/abstracts/search?q=Peclet%20number" title=" Peclet number"> Peclet number</a>, <a href="https://publications.waset.org/abstracts/search?q=permeability" title=" permeability"> permeability</a>, <a href="https://publications.waset.org/abstracts/search?q=porous%20medium" title=" porous medium"> porous medium</a> </p> <a href="https://publications.waset.org/abstracts/85302/experimental-technique-to-study-colloid-deposition-in-porous-media" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/85302.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">186</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">706</span> Effect of Coriolis Force on Magnetoconvection in an Anisotropic Porous Medium</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=N.%20F.%20M.%20Mokhtar">N. F. M. Mokhtar</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Z.%20A.%20Hamid"> N. Z. A. Hamid</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper reports an analytical investigation of the stability and thermal convection in a horizontal anisotropic porous medium in the presence of Coriolis force and magnetic field. The Darcy model is used in the momentum equation and Boussinesq approximation is considered for the density variation of the porous medium. The upper and lower boundaries of the porous medium are assumed to be conducting to temperature perturbation and we used first order Chebyshev polynomial Tau method to solve the resulting eigenvalue problem. Analytical solution is obtained for the case of stationary convection. It is found that the porous layer system becomes unstable when the mechanical anisotropy parameter elevated and increasing the Coriolis force and magnetic field help to stabilize the anisotropy porous medium. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=anisotropic" title="anisotropic">anisotropic</a>, <a href="https://publications.waset.org/abstracts/search?q=Chebyshev%20tau%20method" title=" Chebyshev tau method"> Chebyshev tau method</a>, <a href="https://publications.waset.org/abstracts/search?q=Coriolis%20force" title=" Coriolis force"> Coriolis force</a>, <a href="https://publications.waset.org/abstracts/search?q=Magnetic%20field" title=" Magnetic field"> Magnetic field</a> </p> <a href="https://publications.waset.org/abstracts/96169/effect-of-coriolis-force-on-magnetoconvection-in-an-anisotropic-porous-medium" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/96169.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">214</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">705</span> Optical Characterization of Transition Metal Ion Doped ZnO Microspheres Synthesized via Laser Ablation in Air</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Parvathy%20Anitha">Parvathy Anitha</a>, <a href="https://publications.waset.org/abstracts/search?q=Nilesh%20J.%20Vasa"> Nilesh J. Vasa</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20S.%20Ramachandra%20Rao"> M. S. Ramachandra Rao</a> </p> <p class="card-text"><strong>Abstract:</strong></p> ZnO is a semiconducting material with a direct wide band gap of 3.37 eV and a large exciton binding energy of 60 meV at room temperature. Microspheres with high sphericity and symmetry exhibit unique functionalities which makes them excellent omnidirectional optical resonators. Hence there is an advent interest in fabrication of single crystalline semiconductor microspheres especially magnetic ZnO microspheres, as ZnO is a promising material for semiconductor device applications. Also, ZnO is non-toxic and biocompatible, implying it is a potential material for biomedical applications. Room temperature Photoluminescence (PL) spectra of the fabricated ZnO microspheres were measured, at an excitation wavelength of 325 nm. The ultraviolet (UV) luminescence observed is attributed to the room-temperature free exciton related near-band-edge (NBE) emission in ZnO. Besides the NBE luminescence, weak and broad visible luminescence (~560nm) was also observed. This broad emission band in the visible range is associated with oxygen vacancies related to structural defects. In transition metal (TM) ion-doped ZnO, 3d levels emissions of TM ions will modify the inherent characteristic emissions of ZnO. A micron-sized ZnO crystal has generally a wurtzite structure with a natural hexagonal cross section, which will serve as a WGM (whispering gallery mode) lasing micro cavity due to its high refractive index (~2.2). But hexagonal cavities suffers more optical loss at their corners in comparison to spherical structures; hence spheres may be a better candidate to achieve effective light confinement. In our study, highly smooth spherical shaped micro particles with different diameters ranging from ~4 to 6 μm were grown on different substrates. SEM (Scanning Electron Microscopy) and AFM (Atomic Force Microscopy) images show the presence of uniform smooth surfaced spheres. Raman scattering measurements from the fabricated samples at 488 nm light excitation provide convincing supports for the wurtzite structure of the prepared ZnO microspheres. WGM lasing studies from TM-doped ZnO microparticles are in progress. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=laser%20ablation" title="laser ablation">laser ablation</a>, <a href="https://publications.waset.org/abstracts/search?q=microcavity" title=" microcavity"> microcavity</a>, <a href="https://publications.waset.org/abstracts/search?q=photoluminescence" title=" photoluminescence"> photoluminescence</a>, <a href="https://publications.waset.org/abstracts/search?q=ZnO%20microsphere" title=" ZnO microsphere"> ZnO microsphere</a> </p> <a href="https://publications.waset.org/abstracts/52451/optical-characterization-of-transition-metal-ion-doped-zno-microspheres-synthesized-via-laser-ablation-in-air" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/52451.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">217</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">704</span> Formation and Characterization of the Epoxy Resin-Porous Glass Interphases</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aleksander%20Ostrowski">Aleksander Ostrowski</a>, <a href="https://publications.waset.org/abstracts/search?q=Hugh%20J.%20Byrne"> Hugh J. Byrne</a>, <a href="https://publications.waset.org/abstracts/search?q=Roland%20Sanctuary"> Roland Sanctuary</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Investigation of the polymer interphases is an emerging field nowadays. In many cases interphases determine the functionality of a system. There is a great demand for exploration of fundamental understanding of the interphases and elucidation of their formation, dimensions dependent on various influencing factors, change of functional properties, etc. The epoxy applied on porous glass penetrates its pores with an extent dependent on the pore size, temperature and epoxy components mixing ratio. Developed over the recent time challenging sample preparation procedure allowed to produce very smooth epoxy-porous glass cross-sections. In this study, Raman spectroscopy was used to investigate the epoxy-porous glass interphases. It allowed for chemical differentiation between different regions at the cross-section and determination of the degree of cure of epoxy system in the porous glass. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=interphases" title="interphases">interphases</a>, <a href="https://publications.waset.org/abstracts/search?q=Raman%20spectroscopy" title=" Raman spectroscopy"> Raman spectroscopy</a>, <a href="https://publications.waset.org/abstracts/search?q=epoxy" title=" epoxy"> epoxy</a>, <a href="https://publications.waset.org/abstracts/search?q=porous%20glass" title=" porous glass"> porous glass</a> </p> <a href="https://publications.waset.org/abstracts/9393/formation-and-characterization-of-the-epoxy-resin-porous-glass-interphases" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/9393.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">395</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">703</span> Metal-Semiconductor-Metal Photodetector Based on Porous In0.08Ga0.92N</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Saleh%20H.%20Abud">Saleh H. Abud</a>, <a href="https://publications.waset.org/abstracts/search?q=Z.%20Hassan"> Z. Hassan</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20K.%20Yam"> F. K. Yam</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Characteristics of MSM photodetector based on a porous In0.08Ga0.92N thin film were reported. Nanoporous structures of n-type In0.08Ga0.92N/AlN/Si thin films were synthesized by photoelectrochemical (PEC) etching at a ratio of 1:4 of HF:C2H5OH solution for 15 min. The structural and optical properties of pre- and post-etched thin films were investigated. Field emission scanning electron microscope and atomic force microscope images showed that the pre-etched thin film has a sufficiently smooth surface over a large region and the roughness increased for porous film. Blue shift has been observed in photoluminescence emission peak at 300 K for porous sample. The photoluminescence intensity of the porous film indicated that the optical properties have been enhanced. A high work function metals (Pt and Ni) were deposited as a metal contact on the porous films. The rise and recovery times of the devices were investigated at 390 nm chopped light. Finally, the sensitivity and quantum efficiency were also studied. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=porous%20InGaN" title="porous InGaN">porous InGaN</a>, <a href="https://publications.waset.org/abstracts/search?q=photoluminescence" title=" photoluminescence"> photoluminescence</a>, <a href="https://publications.waset.org/abstracts/search?q=SMS%20photodetector" title=" SMS photodetector"> SMS photodetector</a>, <a href="https://publications.waset.org/abstracts/search?q=atomic%20force%20microscopy" title=" atomic force microscopy"> atomic force microscopy</a> </p> <a href="https://publications.waset.org/abstracts/4022/metal-semiconductor-metal-photodetector-based-on-porous-in008ga092n" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/4022.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">489</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">702</span> Numerical Prediction of Entropy Generation in Heat Exchangers</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nadia%20Allouache">Nadia Allouache</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The concept of second law is assumed to be important to optimize the energy losses in heat exchangers. The present study is devoted to the numerical prediction of entropy generation due to heat transfer and friction in a double tube heat exchanger partly or fully filled with a porous medium. The goal of this work is to find the optimal conditions that allow minimizing entropy generation. For this purpose, numerical modeling based on the control volume method is used to describe the flow and heat transfer phenomena in the fluid and the porous medium. Effects of the porous layer thickness, its permeability, and the effective thermal conductivity have been investigated. Unexpectedly, the fully porous heat exchanger yields a lower entropy generation than the partly porous case or the fluid case even if the friction increases the entropy generation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=heat%20exchangers" title="heat exchangers">heat exchangers</a>, <a href="https://publications.waset.org/abstracts/search?q=porous%20medium" title=" porous medium"> porous medium</a>, <a href="https://publications.waset.org/abstracts/search?q=second%20law%20approach" title=" second law approach"> second law approach</a>, <a href="https://publications.waset.org/abstracts/search?q=turbulent%20flow" title=" turbulent flow"> turbulent flow</a> </p> <a href="https://publications.waset.org/abstracts/63531/numerical-prediction-of-entropy-generation-in-heat-exchangers" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/63531.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">300</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">701</span> Experimental Study of Flow Effects of Solid Particles’ Size in Porous Media</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=S.%20Akridiss">S. Akridiss</a>, <a href="https://publications.waset.org/abstracts/search?q=E.%20El%20Tabach"> E. El Tabach</a>, <a href="https://publications.waset.org/abstracts/search?q=K.%20Chetehouna"> K. Chetehouna</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Gascoin"> N. Gascoin</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20S.%20Kadiri"> M. S. Kadiri</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Transpiration cooling combined to regenerative cooling is a technique that could be used to cool the porous walls of the future ramjet combustion chambers; it consists of using fuel that will flow through the pores of the porous material consisting of the chamber walls, as coolant. However, at high temperature, the fuel is pyrolysed and generates solid coke particles inside the porous materials. This phenomenon can lead to a significant decrease of the material permeability and can affect the efficiency of the cooling system. In order to better understand this phenomenon, an experimental laboratory study was undertaken to determine the transport and deposition of particles in a sintered porous material subjected to steady state flow. The test bench composed of a high-pressure autoclave is used to study the transport of different particle size (35 <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=experimental%20study" title="experimental study">experimental study</a>, <a href="https://publications.waset.org/abstracts/search?q=permeability" title=" permeability"> permeability</a>, <a href="https://publications.waset.org/abstracts/search?q=porous%20material" title=" porous material"> porous material</a>, <a href="https://publications.waset.org/abstracts/search?q=suspended%20particles" title=" suspended particles"> suspended particles</a> </p> <a href="https://publications.waset.org/abstracts/91089/experimental-study-of-flow-effects-of-solid-particles-size-in-porous-media" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/91089.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">274</span> </span> </div> </div> <ul class="pagination"> <li class="page-item disabled"><span class="page-link">&lsaquo;</span></li> <li class="page-item active"><span class="page-link">1</span></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=porous%20microspheres&page=2">2</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=porous%20microspheres&page=3">3</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=porous%20microspheres&page=4">4</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=porous%20microspheres&page=5">5</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=porous%20microspheres&page=6">6</a></li> <li class="page-item"><a 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