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class="row"> <div class="col-sm-12"> <h1 class="font-size-30 fweight-400 color-white">Zeitschrift f&uuml;r Regenerative Medizin </h1> </div> </div> </div> </div> <nav class="navbar navbar-expand-lg bg-navbar navbar-light mega-menu journal-menu topbar-shadow" id="mainNavbar"> <div class="container"> <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbarSupportedContent" aria-controls="navbarSupportedContent" aria-expanded="false" aria-label="Toggle navigation"> <span class="navbar-toggler-icon"></span> </button> <div class="collapse navbar-collapse justify-content-center" id="navbarSupportedContent"> <ul class="navbar-nav mb-auto mb-2 mb-lg-0"> <li class="nav-item"><a class="nav-link" href="https://german.scitechnol.com/journals/regenerative-medicine.html" title="klicken Sie hier"><i class="fa fa-home" aria-hidden="true"></i></a></li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle" href="#" id="navbarDropdown" role="button" 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K&ouml;rper sind verschiedene Klassen von Stammzellen f&uuml;r die Erneuerung verschiedener Gewebetypen verantwortlich. Einige Gewebe scheinen jedoch nicht in der Lage zu sein, sich durch die Entstehung neuer Zellen zu reparieren, da keine kompetenten Stammzellen vorhanden sind. J&uuml;ngste Entdeckungen haben neue M&ouml;glichkeiten er&ouml;ffnet, das Verhalten von Stammzellen k&uuml;nstlich zu manipulieren, um Gewebe zu reparieren, das zuvor nicht reparierbar schien. Epidermale Stammzellen, die aus unbesch&auml;digter Haut eines Patienten mit schweren Verbrennungen entnommen wurden, k&ouml;nnen in Kultur schnell in gro&szlig;en Mengen gez&uuml;chtet und zur&uuml;ckgepfropft werden, um eine Epidermis zur Abdeckung der Verbrennungen wiederherzustellen. Neurale Stammzellen verbleiben in einigen Regionen des Gehirns erwachsener S&auml;ugetiere und k&ouml;nnen bei der Transplantation in ein sich entwickelndes oder gesch&auml;digtes Gehirn neue Neuronen und Gliazellen erzeugen, die f&uuml;r die Transplantationsstelle geeignet sind.</font></font></p> <p style="text-align: justify;"><font style="vertical-align: inherit;"><font style="vertical-align: inherit;">Embryonale Stammzellen (ES-Zellen) sind in der Lage, sich in jeden Zelltyp im K&ouml;rper zu differenzieren, und sie k&ouml;nnen in Kultur dazu gebracht werden, sich in viele Zelltypen zu differenzieren. Stammzellen einiger erwachsener Gewebe, etwa des Knochenmarks, scheinen, wenn sie in einer geeigneten Umgebung platziert werden, in der Lage zu sein, ein viel gr&ouml;&szlig;eres Spektrum differenzierter Zelltypen zu erzeugen, als sie normalerweise produzieren.</font></font></p> <p style="text-align: justify;"><font style="vertical-align: inherit;"><font style="vertical-align: inherit;">Wenn Zellen aus dem K&ouml;rper entnommen und in Kultur gehalten werden, behalten sie im Allgemeinen ihren urspr&uuml;nglichen Charakter. Jeder Typ spezialisierter Zellen hat eine Erinnerung an seine Entwicklungsgeschichte und scheint auf sein spezialisiertes Schicksal festgelegt zu sein, obwohl einige begrenzte Transformationen stattfinden k&ouml;nnen. Stammzellen in Kultur, wie auch in Geweben, k&ouml;nnen sich weiter teilen oder sich in einen oder mehrere Zelltypen differenzieren, die Zelltypen, die sie erzeugen k&ouml;nnen, sind jedoch eingeschr&auml;nkt. Jede Stammzellart dient der Erneuerung einer bestimmten Gewebeart. Bei manchen Geweben, etwa dem Gehirn, ist eine Regeneration im Erwachsenenalter nicht m&ouml;glich, da keine Stammzellen mehr vorhanden sind. Es schien daher wenig Hoffnung zu geben, verlorene Nervenzellen im Gehirn von S&auml;ugetieren durch die Entstehung neuer Zellen zu ersetzen oder einen anderen Zelltyp zu regenerieren, dessen normale Vorl&auml;ufer nicht mehr vorhanden sind.</font></font></p> <p style="text-align: justify;"><font style="vertical-align: inherit;"><font style="vertical-align: inherit;">J&uuml;ngste Entdeckungen haben dieses d&uuml;stere Urteil zunichte gemacht und zu einer optimistischeren Vorstellung davon gef&uuml;hrt, was Stammzellen leisten k&ouml;nnen und wie wir sie m&ouml;glicherweise nutzen k&ouml;nnen. Die Ver&auml;nderung ist auf mehrere Erkenntnisse zur&uuml;ckzuf&uuml;hren, die au&szlig;ergew&ouml;hnliche Formen der Vielseitigkeit von Stammzellen belegen, die man aufgrund der Kenntnis der normalen Lebensgeschichte von Zellen in Geweben kaum h&auml;tte vermuten k&ouml;nnen.</font></font></p> </div> </div> <!-- sidebar --> <div class="col-xs-12 col-md-3"> <div class="divider-v4 divider-v4-left-double bg-color-white padding-10 margin-b-10"> <h2 class="divider-v4-title">Entdecken Sie SciTechnol</h2> <div> <ul class="list-unstyled angle-right"> <li class="color-base"><a href="https://german.scitechnol.com/author-guidelines.html" title="klicken Sie hier"> Autorenrichtlinien</a></li> <li class="color-base"><a href="https://german.scitechnol.com/reviewer-guidelines.html" title="klicken Sie hier"> Richtlinien f眉r Gutachter</a></li> <li class="color-base"><a href="https://german.scitechnol.com/scitechnol-associations-indexing.html" title="klicken Sie hier"> Verb盲nde</a></li> <li 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