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Trombocitopènia - Viquipèdia, l'enciclopèdia lliure

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href="//donate.wikimedia.org/wiki/Special:FundraiserRedirector?utm_source=donate&amp;utm_medium=sidebar&amp;utm_campaign=C13_ca.wikipedia.org&amp;uselang=ca" class=""><span>Donatius</span></a> </li> <li id="pt-createaccount-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=Especial:Crea_compte&amp;returnto=Trombocitop%C3%A8nia" title="Us animem a crear un compte i iniciar una sessió, encara que no és obligatori" class=""><span>Crea un compte</span></a> </li> <li id="pt-login-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=Especial:Registre_i_entrada&amp;returnto=Trombocitop%C3%A8nia" title="Us animem a registrar-vos, però no és obligatori [o]" accesskey="o" class=""><span>Inicia la sessió</span></a> </li> </ul> </div> </div> </div> <div id="vector-user-links-dropdown" class="vector-dropdown vector-user-menu 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data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">Contingut</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">mou a la barra lateral</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">amaga</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">Inici</div> </a> </li> <li id="toc-Signes_i_símptomes" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Signes_i_símptomes"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Signes i símptomes</span> </div> </a> <ul id="toc-Signes_i_símptomes-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Causes" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Causes"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Causes</span> </div> </a> <button aria-controls="toc-Causes-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Commuta la subsecció Causes</span> </button> <ul id="toc-Causes-sublist" class="vector-toc-list"> <li id="toc-Producció_disminuïda" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Producció_disminuïda"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.1</span> <span>Producció disminuïda</span> </div> </a> <ul id="toc-Producció_disminuïda-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Destrucció_augmentada" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Destrucció_augmentada"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.2</span> <span>Destrucció augmentada</span> </div> </a> <ul id="toc-Destrucció_augmentada-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Induït_per_medicació" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Induït_per_medicació"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.3</span> <span>Induït per medicació</span> </div> </a> <ul id="toc-Induït_per_medicació-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Altres_causes" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Altres_causes"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.4</span> <span>Altres causes</span> </div> </a> <ul id="toc-Altres_causes-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Diagnosi" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Diagnosi"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Diagnosi</span> </div> </a> <ul id="toc-Diagnosi-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Tractament" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Tractament"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Tractament</span> </div> </a> <ul id="toc-Tractament-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Trombocitopènia_neonatal" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Trombocitopènia_neonatal"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Trombocitopènia neonatal</span> </div> </a> <ul id="toc-Trombocitopènia_neonatal-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Referències" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Referències"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>Referències</span> </div> </a> <ul id="toc-Referències-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Enllaços_externs" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Enllaços_externs"> <div class="vector-toc-text"> <span class="vector-toc-numb">7</span> <span>Enllaços externs</span> </div> </a> <ul id="toc-Enllaços_externs-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Contingut" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Commuta la taula de continguts." > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Commuta la taula de continguts.</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Trombocitopènia</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Vés a un article en una altra llengua. Disponible en 37 llengües" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-37" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">37 llengües</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D9%82%D9%84%D8%A9_%D8%A7%D9%84%D8%B5%D9%81%D9%8A%D8%AD%D8%A7%D8%AA" title="قلة الصفيحات - àrab" lang="ar" hreflang="ar" data-title="قلة الصفيحات" data-language-autonym="العربية" data-language-local-name="àrab" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-az mw-list-item"><a href="https://az.wikipedia.org/wiki/Trombositopeniya" title="Trombositopeniya - azerbaidjanès" lang="az" hreflang="az" data-title="Trombositopeniya" data-language-autonym="Azərbaycanca" data-language-local-name="azerbaidjanès" class="interlanguage-link-target"><span>Azərbaycanca</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Trombocitopenija" title="Trombocitopenija - bosnià" lang="bs" hreflang="bs" data-title="Trombocitopenija" data-language-autonym="Bosanski" data-language-local-name="bosnià" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Trombocytopenie" title="Trombocytopenie - txec" lang="cs" hreflang="cs" data-title="Trombocytopenie" data-language-autonym="Čeština" data-language-local-name="txec" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Thrombozytopenie" title="Thrombozytopenie - alemany" lang="de" hreflang="de" data-title="Thrombozytopenie" data-language-autonym="Deutsch" data-language-local-name="alemany" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Thrombocytopenia" title="Thrombocytopenia - anglès" lang="en" hreflang="en" data-title="Thrombocytopenia" data-language-autonym="English" data-language-local-name="anglès" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Trombocitopenia" title="Trombocitopenia - espanyol" lang="es" hreflang="es" data-title="Trombocitopenia" data-language-autonym="Español" data-language-local-name="espanyol" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/Tronbopenia" title="Tronbopenia - basc" lang="eu" hreflang="eu" data-title="Tronbopenia" data-language-autonym="Euskara" data-language-local-name="basc" class="interlanguage-link-target"><span>Euskara</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%AA%D8%B1%D9%88%D9%85%D8%A8%D9%88%D8%B3%DB%8C%D8%AA%D9%88%D9%BE%D9%86%DB%8C" title="ترومبوسیتوپنی - persa" lang="fa" hreflang="fa" data-title="ترومبوسیتوپنی" data-language-autonym="فارسی" data-language-local-name="persa" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Trombosytopenia" title="Trombosytopenia - finès" lang="fi" hreflang="fi" data-title="Trombosytopenia" data-language-autonym="Suomi" data-language-local-name="finès" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Thrombop%C3%A9nie" title="Thrombopénie - francès" lang="fr" hreflang="fr" data-title="Thrombopénie" data-language-autonym="Français" data-language-local-name="francès" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Trombopenia" title="Trombopenia - gallec" lang="gl" hreflang="gl" data-title="Trombopenia" data-language-autonym="Galego" data-language-local-name="gallec" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%AA%D7%A8%D7%95%D7%9E%D7%91%D7%95%D7%A6%D7%99%D7%98%D7%95%D7%A4%D7%A0%D7%99%D7%94" title="תרומבוציטופניה - hebreu" lang="he" hreflang="he" data-title="תרומבוציטופניה" data-language-autonym="עברית" data-language-local-name="hebreu" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-hr mw-list-item"><a href="https://hr.wikipedia.org/wiki/Trombocitopenija" title="Trombocitopenija - croat" lang="hr" hreflang="hr" data-title="Trombocitopenija" data-language-autonym="Hrvatski" data-language-local-name="croat" class="interlanguage-link-target"><span>Hrvatski</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Trombositopenia" title="Trombositopenia - indonesi" lang="id" hreflang="id" data-title="Trombositopenia" data-language-autonym="Bahasa Indonesia" data-language-local-name="indonesi" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Piastrinopenia" title="Piastrinopenia - italià" lang="it" hreflang="it" data-title="Piastrinopenia" data-language-autonym="Italiano" data-language-local-name="italià" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E8%A1%80%E5%B0%8F%E6%9D%BF%E6%B8%9B%E5%B0%91%E7%97%87" title="血小板減少症 - japonès" lang="ja" hreflang="ja" data-title="血小板減少症" data-language-autonym="日本語" data-language-local-name="japonès" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%ED%98%88%EC%86%8C%ED%8C%90%EA%B0%90%EC%86%8C%EC%A6%9D" title="혈소판감소증 - coreà" lang="ko" hreflang="ko" data-title="혈소판감소증" data-language-autonym="한국어" data-language-local-name="coreà" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-lt mw-list-item"><a href="https://lt.wikipedia.org/wiki/Trombocitopenija" title="Trombocitopenija - lituà" lang="lt" hreflang="lt" data-title="Trombocitopenija" data-language-autonym="Lietuvių" data-language-local-name="lituà" class="interlanguage-link-target"><span>Lietuvių</span></a></li><li class="interlanguage-link interwiki-mk mw-list-item"><a href="https://mk.wikipedia.org/wiki/%D0%A2%D1%80%D0%BE%D0%BC%D0%B1%D0%BE%D1%86%D0%B8%D1%82%D0%BE%D0%BF%D0%B5%D0%BD%D0%B8%D1%98%D0%B0" title="Тромбоцитопенија - macedoni" lang="mk" hreflang="mk" data-title="Тромбоцитопенија" data-language-autonym="Македонски" data-language-local-name="macedoni" class="interlanguage-link-target"><span>Македонски</span></a></li><li class="interlanguage-link interwiki-mn mw-list-item"><a href="https://mn.wikipedia.org/wiki/%D0%A2%D1%80%D0%BE%D0%BC%D0%B1%D0%BE%D1%86%D0%B8%D1%82%D0%BE%D0%BF%D0%B5%D0%BD%D0%B8" title="Тромбоцитопени - mongol" lang="mn" hreflang="mn" data-title="Тромбоцитопени" data-language-autonym="Монгол" data-language-local-name="mongol" class="interlanguage-link-target"><span>Монгол</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Trombositopenia" title="Trombositopenia - malai" lang="ms" hreflang="ms" data-title="Trombositopenia" data-language-autonym="Bahasa Melayu" data-language-local-name="malai" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Trombocytopenie" title="Trombocytopenie - neerlandès" lang="nl" hreflang="nl" data-title="Trombocytopenie" data-language-autonym="Nederlands" data-language-local-name="neerlandès" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-or mw-list-item"><a href="https://or.wikipedia.org/wiki/%E0%AC%A5%E0%AD%8D%E0%AC%B0%E0%AD%8B%E0%AC%AE%E0%AD%8D%E0%AC%AC%E0%AD%8B%E0%AC%B8%E0%AC%BE%E0%AC%87%E0%AC%9F%E0%AD%8B%E0%AC%AA%E0%AD%87%E0%AC%A8%E0%AC%BF%E0%AC%86" title="ଥ୍ରୋମ୍ବୋସାଇଟୋପେନିଆ - oriya" lang="or" hreflang="or" data-title="ଥ୍ରୋମ୍ବୋସାଇଟୋପେନିଆ" data-language-autonym="ଓଡ଼ିଆ" data-language-local-name="oriya" class="interlanguage-link-target"><span>ଓଡ଼ିଆ</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Ma%C5%82op%C5%82ytkowo%C5%9B%C4%87" title="Małopłytkowość - polonès" lang="pl" hreflang="pl" data-title="Małopłytkowość" data-language-autonym="Polski" data-language-local-name="polonès" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Trombocitopenia" title="Trombocitopenia - portuguès" lang="pt" hreflang="pt" data-title="Trombocitopenia" data-language-autonym="Português" data-language-local-name="portuguès" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%A2%D1%80%D0%BE%D0%BC%D0%B1%D0%BE%D1%86%D0%B8%D1%82%D0%BE%D0%BF%D0%B5%D0%BD%D0%B8%D1%8F" title="Тромбоцитопения - rus" lang="ru" hreflang="ru" data-title="Тромбоцитопения" data-language-autonym="Русский" data-language-local-name="rus" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Trombocitopenija" title="Trombocitopenija - serbocroat" lang="sh" hreflang="sh" data-title="Trombocitopenija" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="serbocroat" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-simple mw-list-item"><a href="https://simple.wikipedia.org/wiki/Thrombocytopenia" title="Thrombocytopenia - Simple English" lang="en-simple" hreflang="en-simple" data-title="Thrombocytopenia" data-language-autonym="Simple English" data-language-local-name="Simple English" class="interlanguage-link-target"><span>Simple English</span></a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Trombocitopenija" title="Trombocitopenija - eslovè" lang="sl" hreflang="sl" data-title="Trombocitopenija" data-language-autonym="Slovenščina" data-language-local-name="eslovè" class="interlanguage-link-target"><span>Slovenščina</span></a></li><li class="interlanguage-link interwiki-sq mw-list-item"><a href="https://sq.wikipedia.org/wiki/Trombocitopeni" title="Trombocitopeni - albanès" lang="sq" hreflang="sq" data-title="Trombocitopeni" data-language-autonym="Shqip" data-language-local-name="albanès" class="interlanguage-link-target"><span>Shqip</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Trombocitopenija" title="Trombocitopenija - serbi" lang="sr" hreflang="sr" data-title="Trombocitopenija" data-language-autonym="Српски / srpski" data-language-local-name="serbi" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Trombocytopeni" title="Trombocytopeni - suec" lang="sv" hreflang="sv" data-title="Trombocytopeni" data-language-autonym="Svenska" data-language-local-name="suec" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-th mw-list-item"><a href="https://th.wikipedia.org/wiki/%E0%B9%80%E0%B8%81%E0%B8%A5%E0%B9%87%E0%B8%94%E0%B9%80%E0%B8%A5%E0%B8%B7%E0%B8%AD%E0%B8%94%E0%B8%99%E0%B9%89%E0%B8%AD%E0%B8%A2" title="เกล็ดเลือดน้อย - tai" lang="th" hreflang="th" data-title="เกล็ดเลือดน้อย" data-language-autonym="ไทย" data-language-local-name="tai" class="interlanguage-link-target"><span>ไทย</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Trombositopeni" title="Trombositopeni - turc" lang="tr" hreflang="tr" data-title="Trombositopeni" data-language-autonym="Türkçe" data-language-local-name="turc" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%A2%D1%80%D0%BE%D0%BC%D0%B1%D0%BE%D1%86%D0%B8%D1%82%D0%BE%D0%BF%D0%B5%D0%BD%D1%96%D1%8F" title="Тромбоцитопенія - ucraïnès" lang="uk" hreflang="uk" data-title="Тромбоцитопенія" data-language-autonym="Українська" data-language-local-name="ucraïnès" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E8%A1%80%E5%B0%8F%E6%9D%BF%E6%B8%9B%E5%B0%91%E7%97%87" title="血小板減少症 - xinès" lang="zh" hreflang="zh" data-title="血小板減少症" data-language-autonym="中文" data-language-local-name="xinès" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a 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id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Aparença"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Aparença</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">mou a la barra lateral</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">amaga</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">De la Viquipèdia, l&#039;enciclopèdia lliure</div> </div> <div id="contentSub"><div id="mw-content-subtitle"><span class="mw-redirectedfrom">(S'ha redirigit des de: <a href="/w/index.php?title=Trombop%C3%A8nia&amp;redirect=no" class="mw-redirect" title="Trombopènia">Trombopènia</a>)</span></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="ca" dir="ltr"><table class="infobox" style="font-size:90%;width:25em"><caption style="font-weight:bold;background-color:#b0d1ad;background-color:#b0d1ad;valign=center; padding:1px;"><span style="float:left;margin:1.5px"><span typeof="mw:File"><a href="/wiki/Fitxer:Arrythmia_noun_246518_cc.svg" class="mw-file-description" title="Plantilla:Infotaula malaltia"><img alt="Plantilla:Infotaula malaltia" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/35/Arrythmia_noun_246518_cc.svg/22px-Arrythmia_noun_246518_cc.svg.png" decoding="async" width="22" height="21" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/35/Arrythmia_noun_246518_cc.svg/33px-Arrythmia_noun_246518_cc.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/35/Arrythmia_noun_246518_cc.svg/44px-Arrythmia_noun_246518_cc.svg.png 2x" data-file-width="53" data-file-height="51" /></a></span></span>Trombocitopènia</caption><tbody><tr><td colspan="2" class="infobox-full-data infobox-data" style="text-align:center;padding-bottom:0.1em;line-height:1.35;font-size:98%"><span typeof="mw:File"><a href="/wiki/Fitxer:Trombocitopenia_01.JPG" class="mw-file-description"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/c/c7/Trombocitopenia_01.JPG/300px-Trombocitopenia_01.JPG" decoding="async" width="300" height="191" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/c7/Trombocitopenia_01.JPG/450px-Trombocitopenia_01.JPG 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/c7/Trombocitopenia_01.JPG/600px-Trombocitopenia_01.JPG 2x" data-file-width="2986" data-file-height="1906" /></a></span> <span data-bridge-edit-flow="overwrite"><span class="mw-valign-baseline" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q585285?uselang=ca#P18" title="modifica"><img alt="modifica" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/10px-Arbcom_ru_editing.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/15px-Arbcom_ru_editing.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/20px-Arbcom_ru_editing.svg.png 2x" data-file-width="600" data-file-height="600" /></a></span></span></td></tr><tr><th scope="row" class="infobox-label" style="text-align:left;padding-right:1.2em;background:#eeeeee; text-align:start">Tipus</th><td class="infobox-data" style="text-align:start"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q2429620" class="extiw" title="d:Special:EntityPage/Q2429620">trombocitopatia</a>, <a href="/wiki/Signe_cl%C3%ADnic" title="Signe clínic">signe clínic</a>, <a href="https://www.wikidata.org/wiki/Special:EntityPage/Q102186671" class="extiw" title="d:Special:EntityPage/Q102186671">signe o símptoma hematològic</a> i <a href="/wiki/Malaltia" title="Malaltia">malaltia</a> <span class="penicon"><span class="mw-valign-baseline" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q585285?uselang=ca#P279" title="Modifica el valor a Wikidata"><img alt="Modifica el valor a Wikidata" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/10px-Arbcom_ru_editing.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/15px-Arbcom_ru_editing.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/20px-Arbcom_ru_editing.svg.png 2x" data-file-width="600" data-file-height="600" /></a></span></span></td></tr><tr><th scope="row" class="infobox-label" style="text-align:left;padding-right:1.2em;background:#eeeeee; text-align:start"><a href="/wiki/Especialitat_m%C3%A8dica" title="Especialitat mèdica">Especialitat</a></th><td class="infobox-data" style="text-align:start"><a href="/wiki/Hematologia" title="Hematologia">hematologia</a> <span class="penicon"><span class="mw-valign-baseline" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q585285?uselang=ca#P1995" title="Modifica el valor a Wikidata"><img alt="Modifica el valor a Wikidata" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/10px-Arbcom_ru_editing.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/15px-Arbcom_ru_editing.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/20px-Arbcom_ru_editing.svg.png 2x" data-file-width="600" data-file-height="600" /></a></span></span></td></tr><tr><th colspan="2" class="infobox-header" style="text-align:center;background-color:#b0d1ad;background-color:#b0d1ad;">Clínica-tractament</th></tr><tr><th scope="row" class="infobox-label" style="text-align:left;padding-right:1.2em;background:#eeeeee; text-align:start">Exàmens</th><td class="infobox-data" style="text-align:start"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q48634035" class="extiw" title="d:Special:EntityPage/Q48634035">blood platelet count</a> <sup>(en)</sup> <span class="mw-valign-baseline skin-invert" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q48634035?uselang=ca" title="Tradueix"><img alt="Tradueix" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/10px-Noun_Project_label_icon_1116097_cc_mirror.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/15px-Noun_Project_label_icon_1116097_cc_mirror.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/20px-Noun_Project_label_icon_1116097_cc_mirror.svg.png 2x" data-file-width="158" data-file-height="161" /></a></span> <span class="penicon"><span class="mw-valign-baseline" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q585285?uselang=ca#P923" title="Modifica el valor a Wikidata"><img alt="Modifica el valor a Wikidata" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/10px-Arbcom_ru_editing.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/15px-Arbcom_ru_editing.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/20px-Arbcom_ru_editing.svg.png 2x" data-file-width="600" data-file-height="600" /></a></span></span></td></tr><tr><td colspan="2" class="infobox-full-data infobox-data" style="text-align:center;text-align:start"><div class="mw-collapsible" style="border:none; padding: 0;"><div style="width:100%; background:#d5e0d4" align="left">&#160;<b>Medicació</b></div><div class="mw-collapsible-content" style="background:transparent;text-align:left;"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q474880" class="extiw" title="d:Special:EntityPage/Q474880">(21R)-argatroban</a> <sup>(en)</sup> <span class="mw-valign-baseline skin-invert" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q474880?uselang=ca" title="Tradueix"><img alt="Tradueix" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/10px-Noun_Project_label_icon_1116097_cc_mirror.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/15px-Noun_Project_label_icon_1116097_cc_mirror.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/20px-Noun_Project_label_icon_1116097_cc_mirror.svg.png 2x" data-file-width="158" data-file-height="161" /></a></span>, <a href="/wiki/Desmopressina" title="Desmopressina">desmopressina</a>, <a href="https://www.wikidata.org/wiki/Special:EntityPage/Q3271949" class="extiw" title="d:Special:EntityPage/Q3271949">lepirudin</a> <sup>(en)</sup> <span class="mw-valign-baseline skin-invert" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q3271949?uselang=ca" title="Tradueix"><img alt="Tradueix" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/10px-Noun_Project_label_icon_1116097_cc_mirror.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/15px-Noun_Project_label_icon_1116097_cc_mirror.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/20px-Noun_Project_label_icon_1116097_cc_mirror.svg.png 2x" data-file-width="158" data-file-height="161" /></a></span>, <a href="https://www.wikidata.org/wiki/Special:EntityPage/Q408163" class="extiw" title="d:Special:EntityPage/Q408163">anagrelida</a>, <a href="https://www.wikidata.org/wiki/Special:EntityPage/Q411588" class="extiw" title="d:Special:EntityPage/Q411588">eltrombopag</a>, <a href="https://www.wikidata.org/wiki/Special:EntityPage/Q7383611" class="extiw" title="d:Special:EntityPage/Q7383611">ruxolitinib</a>, <a href="https://www.wikidata.org/wiki/Special:EntityPage/Q1235195" class="extiw" title="d:Special:EntityPage/Q1235195">romiplostim</a> <sup>(en)</sup> <span class="mw-valign-baseline skin-invert" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q1235195?uselang=ca" title="Tradueix"><img alt="Tradueix" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/10px-Noun_Project_label_icon_1116097_cc_mirror.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/15px-Noun_Project_label_icon_1116097_cc_mirror.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/20px-Noun_Project_label_icon_1116097_cc_mirror.svg.png 2x" data-file-width="158" data-file-height="161" /></a></span>, <a href="/wiki/Rituximab" title="Rituximab">rituximab</a> i <a href="https://www.wikidata.org/wiki/Special:EntityPage/Q3271949" class="extiw" title="d:Special:EntityPage/Q3271949">lepirudin</a> <sup>(en)</sup> <span class="mw-valign-baseline skin-invert" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q3271949?uselang=ca" title="Tradueix"><img alt="Tradueix" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/10px-Noun_Project_label_icon_1116097_cc_mirror.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/15px-Noun_Project_label_icon_1116097_cc_mirror.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/20px-Noun_Project_label_icon_1116097_cc_mirror.svg.png 2x" data-file-width="158" data-file-height="161" /></a></span> <span class="penicon"><span class="mw-valign-baseline" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q585285?uselang=ca#P2176" title="Modifica el valor a Wikidata"><img alt="Modifica el valor a Wikidata" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/10px-Arbcom_ru_editing.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/15px-Arbcom_ru_editing.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/20px-Arbcom_ru_editing.svg.png 2x" data-file-width="600" data-file-height="600" /></a></span></span></div></div></td></tr><tr><th colspan="2" class="infobox-header" style="text-align:center;background-color:#b0d1ad;background-color:#b0d1ad;"><a href="/wiki/Patog%C3%A8nesi" title="Patogènesi">Patogènesi</a></th></tr><tr><th scope="row" class="infobox-label" style="text-align:left;padding-right:1.2em;background:#eeeeee; text-align:start">Associació genètica</th><td class="infobox-data" style="text-align:start"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q14863971" class="extiw" title="d:Special:EntityPage/Q14863971">Proteïna de la síndrome de Wiskott-Aldrich</a>, <a href="https://www.wikidata.org/wiki/Special:EntityPage/Q18036536" class="extiw" title="d:Special:EntityPage/Q18036536">ANKRD26</a> <sup>(en)</sup> <span class="mw-valign-baseline skin-invert" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q18036536?uselang=ca" title="Tradueix"><img alt="Tradueix" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/10px-Noun_Project_label_icon_1116097_cc_mirror.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/15px-Noun_Project_label_icon_1116097_cc_mirror.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/20px-Noun_Project_label_icon_1116097_cc_mirror.svg.png 2x" data-file-width="158" data-file-height="161" /></a></span>, <a href="https://www.wikidata.org/wiki/Special:EntityPage/Q14819361" class="extiw" title="d:Special:EntityPage/Q14819361">citocrom c</a> i <a href="https://www.wikidata.org/wiki/Special:EntityPage/Q14916151" class="extiw" title="d:Special:EntityPage/Q14916151">GATA1</a> <sup>(en)</sup> <span class="mw-valign-baseline skin-invert" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q14916151?uselang=ca" title="Tradueix"><img alt="Tradueix" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/10px-Noun_Project_label_icon_1116097_cc_mirror.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/15px-Noun_Project_label_icon_1116097_cc_mirror.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/20px-Noun_Project_label_icon_1116097_cc_mirror.svg.png 2x" data-file-width="158" data-file-height="161" /></a></span> <span class="penicon"><span class="mw-valign-baseline" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q585285?uselang=ca#P2293" title="Modifica el valor a Wikidata"><img alt="Modifica el valor a Wikidata" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/10px-Arbcom_ru_editing.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/15px-Arbcom_ru_editing.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/20px-Arbcom_ru_editing.svg.png 2x" data-file-width="600" data-file-height="600" /></a></span></span></td></tr><tr><th colspan="2" class="infobox-header" style="text-align:center;background-color:#b0d1ad;background-color:#b0d1ad;">Classificació</th></tr><tr><th scope="row" class="infobox-label" style="text-align:left;padding-right:1.2em;background:#eeeeee; text-align:start"><a href="/wiki/CIM-11" title="CIM-11">CIM-11</a></th><td class="infobox-data" style="text-align:start">3B64 <span class="penicon"><span class="mw-valign-baseline" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q585285?uselang=ca#P7329" title="Modifica el valor a Wikidata"><img alt="Modifica el valor a Wikidata" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/10px-Arbcom_ru_editing.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/15px-Arbcom_ru_editing.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/20px-Arbcom_ru_editing.svg.png 2x" data-file-width="600" data-file-height="600" /></a></span></span></td></tr><tr><th scope="row" class="infobox-label" style="text-align:left;padding-right:1.2em;background:#eeeeee; text-align:start"><a href="/wiki/CIM-10" title="CIM-10">CIM-10</a></th><td class="infobox-data" style="text-align:start"><a href="/wiki/CIM-10_Cap%C3%ADtol_D2" class="mw-redirect" title="CIM-10 Capítol D2">D</a><a rel="nofollow" class="external text" href="http://apps.who.int/classifications/icd10/browse/2010/en#/D69.6">69.6</a>, <a href="/wiki/CIM-10_Cap%C3%ADtol_P" class="mw-redirect" title="CIM-10 Capítol P">P</a><a rel="nofollow" class="external text" href="http://apps.who.int/classifications/icd10/browse/2010/en#/P61.0">61.0</a></td></tr><tr><th scope="row" class="infobox-label" style="text-align:left;padding-right:1.2em;background:#eeeeee; text-align:start"><a href="/wiki/CIM-9" title="CIM-9">CIM-9</a></th><td class="infobox-data" style="text-align:start"><a rel="nofollow" class="external text" href="http://www.saniwiki.cat/ICD/php-09/287.3.php">287.3</a>, <a rel="nofollow" class="external text" href="http://www.saniwiki.cat/ICD/php-09/287.4.php">287.4</a>, <a rel="nofollow" class="external text" href="http://www.saniwiki.cat/ICD/php-09/287.5.php">287.5</a></td></tr><tr><th colspan="2" class="infobox-header" style="text-align:center;background-color:#b0d1ad;background-color:#b0d1ad;">Recursos externs</th></tr><tr><th scope="row" class="infobox-label" style="text-align:left;padding-right:1.2em;background:#eeeeee; text-align:start"><a href="/wiki/Mendelian_Inheritance_in_Man" title="Mendelian Inheritance in Man">OMIM</a></th><td class="infobox-data" style="text-align:start"><a rel="nofollow" class="external text" href="https://omim.org/entry/188000">188000</a> <a rel="nofollow" class="external text" href="http://omim.org/entry/313900">313900</a></td></tr><tr><th scope="row" class="infobox-label" style="text-align:left;padding-right:1.2em;background:#eeeeee; text-align:start"><a href="/wiki/Diseases_Database" title="Diseases Database">DiseasesDB</a></th><td class="infobox-data" style="text-align:start"><a rel="nofollow" class="external text" href="http://www.diseasesdatabase.com/ddb27522.htm">27522</a></td></tr><tr><th scope="row" class="infobox-label" style="text-align:left;padding-right:1.2em;background:#eeeeee; text-align:start"><a href="/wiki/MedlinePlus" title="MedlinePlus">MedlinePlus</a></th><td class="infobox-data" style="text-align:start"><a rel="nofollow" class="external text" href="http://www.nlm.nih.gov/medlineplus/ency/article/000586.htm">000586</a></td></tr><tr><th scope="row" class="infobox-label" style="text-align:left;padding-right:1.2em;background:#eeeeee; text-align:start"><a href="/wiki/Patient_UK" title="Patient UK">Patient UK</a></th><td class="infobox-data" style="text-align:start"><a rel="nofollow" class="external text" href="https://patient.info/doctor/thrombocytopenia">thrombocytopenia</a> <span class="penicon"><span class="mw-valign-baseline" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q585285?uselang=ca#P1461" title="Modifica el valor a Wikidata"><img alt="Modifica el valor a Wikidata" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/10px-Arbcom_ru_editing.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/15px-Arbcom_ru_editing.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/20px-Arbcom_ru_editing.svg.png 2x" data-file-width="600" data-file-height="600" /></a></span></span></td></tr><tr><th scope="row" class="infobox-label" style="text-align:left;padding-right:1.2em;background:#eeeeee; text-align:start"><a href="/wiki/Medical_Subject_Headings" title="Medical Subject Headings">MeSH</a></th><td class="infobox-data" style="text-align:start"><a rel="nofollow" class="external text" href="https://www.nlm.nih.gov/cgi/mesh/2024/MB_cgi?field=uid&amp;term=D013921">D013921</a> <span class="penicon"><span class="mw-valign-baseline" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q585285?uselang=ca#P486" title="Modifica el valor a Wikidata"><img alt="Modifica el valor a Wikidata" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/10px-Arbcom_ru_editing.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/15px-Arbcom_ru_editing.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/20px-Arbcom_ru_editing.svg.png 2x" data-file-width="600" data-file-height="600" /></a></span></span></td></tr><tr><th scope="row" class="infobox-label" style="text-align:left;padding-right:1.2em;background:#eeeeee; text-align:start"><a href="/wiki/Orphanet" title="Orphanet">Orphanet</a></th><td class="infobox-data" style="text-align:start"><a rel="nofollow" class="external text" href="https://www.orpha.net/ORDO/Orphanet_852">852</a> i <a rel="nofollow" class="external text" href="https://www.orpha.net/ORDO/Orphanet_168629">168629</a> <span class="penicon"><span class="mw-valign-baseline" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q585285?uselang=ca#P1550" title="Modifica el valor a Wikidata"><img alt="Modifica el valor a Wikidata" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/10px-Arbcom_ru_editing.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/15px-Arbcom_ru_editing.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/20px-Arbcom_ru_editing.svg.png 2x" data-file-width="600" data-file-height="600" /></a></span></span></td></tr><tr><th scope="row" class="infobox-label" style="text-align:left;padding-right:1.2em;background:#eeeeee; text-align:start"><a href="/wiki/Unified_Medical_Language_System" title="Unified Medical Language System">UMLS</a> <a href="/wiki/Concept_Unique_Identifier" title="Concept Unique Identifier">CUI</a></th><td class="infobox-data" style="text-align:start"><a rel="nofollow" class="external text" href="https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI%20Metathesaurus&amp;code=C0040034">C0040034</a>, <a rel="nofollow" class="external text" href="https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI%20Metathesaurus&amp;code=C0040034">C0040034</a> i <a rel="nofollow" class="external text" href="https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI%20Metathesaurus&amp;code=C0392386">C0392386</a> <span class="penicon"><span class="mw-valign-baseline" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q585285?uselang=ca#P2892" title="Modifica el valor a Wikidata"><img alt="Modifica el valor a Wikidata" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/10px-Arbcom_ru_editing.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/15px-Arbcom_ru_editing.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/20px-Arbcom_ru_editing.svg.png 2x" data-file-width="600" data-file-height="600" /></a></span></span></td></tr><tr><th scope="row" class="infobox-label" style="text-align:left;padding-right:1.2em;background:#eeeeee; text-align:start"><a href="/wiki/Disease_Ontology" title="Disease Ontology">DOID</a></th><td class="infobox-data" style="text-align:start"><a rel="nofollow" class="external text" href="http://www.disease-ontology.org/?id=DOID:1588">DOID:1588</a> <span class="penicon"><span class="mw-valign-baseline" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q585285?uselang=ca#P699" title="Modifica el valor a Wikidata"><img alt="Modifica el valor a Wikidata" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/10px-Arbcom_ru_editing.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/15px-Arbcom_ru_editing.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/63/Arbcom_ru_editing.svg/20px-Arbcom_ru_editing.svg.png 2x" data-file-width="600" data-file-height="600" /></a></span></span></td></tr></tbody></table> <p><b>Trombocitopènia</b> o <b>trombopènia</b> és una disminució relativa de <a href="/wiki/Plaqueta" title="Plaqueta">plaquetes</a> en <a href="/wiki/Sang" title="Sang">sang</a>. Un recompte de plaquetes humà normal s'estén de 150.000 a 450.000 plaquetes per micro<a href="/wiki/Litre" title="Litre">litre</a> de sang.<sup id="cite_ref-lto_1-0" class="reference"><a href="#cite_note-lto-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup> Aquests límits estan determinats pels <a href="/wiki/Percentil" class="mw-redirect" title="Percentil">percentils</a> 2,5 inferior i superior, així els valors fora d'aquest rang no indiquen necessàriament una malaltia. Una definició comuna de trombocitopènia és aquell recompte de plaquetes per sota 50.000 per microlitre.<sup id="cite_ref-pmid19118853_2-0" class="reference"><a href="#cite_note-pmid19118853-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-pmid15896582_3-0" class="reference"><a href="#cite_note-pmid15896582-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Signes_i_símptomes"><span id="Signes_i_s.C3.ADmptomes"></span>Signes i símptomes</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Trombocitop%C3%A8nia&amp;action=edit&amp;section=1" title="Modifica la secció: Signes i símptomes"><span>modifica</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Sovint, nivells de plaquetes baixos no s'associen a problemes clínics; més aviat, s'inclouen en els <a href="/wiki/Hemograma" title="Hemograma">hemogrames</a> rutinaris. Ocasionalment, són deguts a <a href="/wiki/Contusi%C3%B3" title="Contusió">contusions</a>, especialment <a href="/wiki/P%C3%BArpura_(medicina)" title="Púrpura (medicina)">púrpura</a> als <a href="/wiki/Avantbra%C3%A7os" class="mw-redirect" title="Avantbraços">avantbraços</a>, <a href="/wiki/Pet%C3%A8quia" title="Petèquia">petèquia</a> (concreti hemorràgies a pell i membranes mucoses), <a href="/wiki/Epistaxi" title="Epistaxi">hemorràgies nasals</a> i/o <a href="/wiki/Geniva" title="Geniva">genivals</a>. </p><p>És vital recopilar una <a href="/w/index.php?title=Hist%C3%B2ria_m%C3%A8dica&amp;action=edit&amp;redlink=1" class="new" title="Història mèdica (encara no existeix)">història mèdica</a> exhaustiva per assegurar que un recompte de plaquetes baix no sigui causat per un procés secundari. També és important assegurar que tampoc hagin disminuït els altres tipus de <a href="/wiki/C%C3%A8l%C2%B7lules_sangu%C3%ADnies" class="mw-redirect" title="Cèl·lules sanguínies">cèl·lules sanguínies</a>, com <a href="/wiki/Gl%C3%B2bul_vermell" title="Glòbul vermell">glòbuls vermells</a> i <a href="/wiki/Leuc%C3%B2cit" title="Leucòcit">glòbuls blancs</a>. </p><p>Normalment apareixen i desapareixen petèquies puntuals, rodones i indolores (1 a 3&#160;mm en diàmetre), i a vegades s'agrupen per formar <a href="/wiki/Equimosi" title="Equimosi">equimosi</a>. Més gran que les petèquies, les equimosis són d'un color blau morat, blau o groc verdòs que varien en mida i forma. Poden ocórrer qualsevol lloc al cos. </p><p>Una persona amb trombocitopènia també es pot queixar de <a href="/wiki/Malestar" title="Malestar">malestar</a>, debilitat i <a href="/wiki/Cansament" class="mw-redirect" title="Cansament">fatiga</a> general (amb pèrdua de sang o sense). En la trombocitopènia adquirida, la història del pacient pot incloure l'ús d'una o més drogues il·legals. </p><p>La inspecció típicament mostra evidència d'hemorràgia (petequial o equimosis), junt amb hemorràgia lenta, contínua des d'algunes lesions o ferides. Els adults poden tenir grans <a href="/wiki/Butllofes" class="mw-redirect" title="Butllofes">butllofes</a> a la boca plenes de sang. Si el recompte de plaquetes de la persona és entre 30.000 i 50.000/mm³, és possible l'aparició de contusions amb traumes menors; si és entre 15.000 i 30.000/mm³, aquestes contuisions espontànies apareixen principalment a braços i cames. </p> <div class="mw-heading mw-heading2"><h2 id="Causes">Causes</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Trombocitop%C3%A8nia&amp;action=edit&amp;section=2" title="Modifica la secció: Causes"><span>modifica</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Els recomptes de plaquetes disminuïts poden ser a causa d'un cert nombre de processos de malaltia: </p> <div class="mw-heading mw-heading3"><h3 id="Producció_disminuïda"><span id="Producci.C3.B3_disminu.C3.AFda"></span>Producció disminuïda</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Trombocitop%C3%A8nia&amp;action=edit&amp;section=3" title="Modifica la secció: Producció disminuïda"><span>modifica</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li>Deficiència de <a href="/wiki/Vitamina_B%E2%82%81%E2%82%82" title="Vitamina B₁₂">vitamina&#160;B₁₂</a> o d'<a href="/wiki/%C3%80cid_f%C3%B2lic" title="Àcid fòlic">àcid fòlic</a></li> <li><a href="/wiki/Leuc%C3%A8mia" title="Leucèmia">Leucèmia</a> o <a href="/wiki/S%C3%ADndrome_mielodispl%C3%A0stica" title="Síndrome mielodisplàstica">síndrome mielodisplàstica</a></li> <li>Producció disminuïda de <a href="/wiki/Trombopoetina" title="Trombopoetina">trombopoetina</a> pel <a href="/wiki/Fetge" title="Fetge">fetge</a> en la <a href="/wiki/Insufici%C3%A8ncia_hep%C3%A0tica" title="Insuficiència hepàtica">insuficiència hepàtica</a>.</li> <li><a href="/wiki/S%C3%A8psia" title="Sèpsia">Sèpsia</a> o infecció sistèmica <a href="/wiki/Virus" title="Virus">vírica</a> o <a href="/wiki/Bacteri_patogen" title="Bacteri patogen">bacteriana</a>.</li> <li>El <a href="/wiki/Dengue" title="Dengue">dengue</a> pot provocar trombocitopènia per infecció directa de <a href="/wiki/Megacari%C3%B2cit" title="Megacariòcit">megacariòcits</a> de la <a href="/wiki/Medul%C2%B7la_%C3%B2ssia" title="Medul·la òssia">medul·la òssia</a> així com una baixa pervivència immunològica de <a href="/wiki/Plaqueta" title="Plaqueta">plaquetes</a></li> <li>Síndromes hereditàries <ul><li><a href="/w/index.php?title=Trombocitop%C3%A8nia_amegacarioc%C3%ADtica_cong%C3%A8nita&amp;action=edit&amp;redlink=1" class="new" title="Trombocitopènia amegacariocítica congènita (encara no existeix)">Trombocitopènia amegacariocítica congènita</a> (CAMT)</li> <li><a href="/w/index.php?title=S%C3%ADndrome_TAR&amp;action=edit&amp;redlink=1" class="new" title="Síndrome TAR (encara no existeix)">Síndrome TAR</a></li> <li><a href="/wiki/An%C3%A8mia_de_Fanconi" title="Anèmia de Fanconi">Anèmia de Fanconi</a></li> <li><a href="/w/index.php?title=S%C3%ADndrome_de_Bernard-Soulier&amp;action=edit&amp;redlink=1" class="new" title="Síndrome de Bernard-Soulier (encara no existeix)">Síndrome de Bernard-Soulier</a>, associat amb plaquetes grans</li> <li><a href="/w/index.php?title=Anomalia_de_May-Hegglin&amp;action=edit&amp;redlink=1" class="new" title="Anomalia de May-Hegglin (encara no existeix)">Anomalia de May-Hegglin</a>, la combinació de trombocitopènia, inclusions leucocítiques blau pàl·lid, i plaquetes gegants</li> <li><a href="/w/index.php?title=S%C3%ADndrome_de_plaquetes_de_Gray&amp;action=edit&amp;redlink=1" class="new" title="Síndrome de plaquetes de Gray (encara no existeix)">Síndrome de plaquetes de Gray</a></li> <li><a href="/wiki/S%C3%ADndrome_d%27Alport" title="Síndrome d&#39;Alport">Síndrome d'Alport</a></li> <li><a href="/w/index.php?title=S%C3%ADndrome_de_Wiskott-Aldrich&amp;action=edit&amp;redlink=1" class="new" title="Síndrome de Wiskott-Aldrich (encara no existeix)">Síndrome de Wiskott-Aldrich</a></li></ul></li></ul> <div class="mw-heading mw-heading3"><h3 id="Destrucció_augmentada"><span id="Destrucci.C3.B3_augmentada"></span>Destrucció augmentada</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Trombocitop%C3%A8nia&amp;action=edit&amp;section=4" title="Modifica la secció: Destrucció augmentada"><span>modifica</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/P%C3%BArpura_trombocitop%C3%A8nica_idiop%C3%A0tica" title="Púrpura trombocitopènica idiopàtica">Púrpura trombocitopènica idiopàtica</a> (PTI)</li> <li><a href="/wiki/P%C3%BArpura_trombocitop%C3%A8nica_tromb%C3%B2tica" title="Púrpura trombocitopènica trombòtica">Púrpura trombocitopènica trombòtica</a> (TTP)</li> <li><a href="/wiki/S%C3%ADndrome_hemol%C3%ADticour%C3%A8mica" class="mw-redirect" title="Síndrome hemolíticourèmica">Síndrome hemolíticourèmica</a> (SHU)</li> <li><a href="/wiki/Coagulaci%C3%B3_intravascular_disseminada" title="Coagulació intravascular disseminada">Coagulació intravascular disseminada</a> (DIC)</li> <li><a href="/wiki/Hemoglobin%C3%BAria_parox%C3%ADstica_nocturna" title="Hemoglobinúria paroxística nocturna">Hemoglobinúria paroxística nocturna</a> (HPN)</li> <li><a href="/w/index.php?title=S%C3%ADndrome_antifosfol%C3%ADpids&amp;action=edit&amp;redlink=1" class="new" title="Síndrome antifosfolípids (encara no existeix)">Síndrome antifosfolípids</a></li> <li><a href="/wiki/Lupus_eritemat%C3%B3s_sist%C3%A8mic" title="Lupus eritematós sistèmic">Lupus eritematós sistèmic</a> (LES)</li> <li><a href="/w/index.php?title=P%C3%BArpura_post-transfusi%C3%B3&amp;action=edit&amp;redlink=1" class="new" title="Púrpura post-transfusió (encara no existeix)">Púrpura post-transfusió</a></li> <li><a href="/w/index.php?title=Trombocitop%C3%A8nia_alloimmune_neonatal&amp;action=edit&amp;redlink=1" class="new" title="Trombocitopènia alloimmune neonatal (encara no existeix)">Trombocitopènia alloimmune neonatal</a> (NAITP)</li> <li>Segrest de plaquetes causada per <a href="/wiki/Esplenomeg%C3%A0lia" title="Esplenomegàlia">esplenomegàlia</a></li> <li><a href="/wiki/Dengue" title="Dengue">Dengue</a> provoca un escurçament de la supervivència de plaquetes i destrucció immunològica de plaquetes</li> <li><a href="/w/index.php?title=Trombocitop%C3%A8nia_associada_a_VIH&amp;action=edit&amp;redlink=1" class="new" title="Trombocitopènia associada a VIH (encara no existeix)">Trombocitopènia associada a VIH</a><sup id="cite_ref-pmid11914001_4-0" class="reference"><a href="#cite_note-pmid11914001-4"><span class="cite-bracket">&#91;</span>4<span class="cite-bracket">&#93;</span></a></sup></li></ul> <div class="mw-heading mw-heading3"><h3 id="Induït_per_medicació"><span id="Indu.C3.AFt_per_medicaci.C3.B3"></span>Induït per medicació</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Trombocitop%C3%A8nia&amp;action=edit&amp;section=5" title="Modifica la secció: Induït per medicació"><span>modifica</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Les medicacions que provoquen trombocitopènia inclouen:<sup id="cite_ref-urlmoon.ouhsc.edu_5-0" class="reference"><a href="#cite_note-urlmoon.ouhsc.edu-5"><span class="cite-bracket">&#91;</span>5<span class="cite-bracket">&#93;</span></a></sup> </p> <ul><li><b>Mielosupressió directa:</b> <ul><li><a href="/wiki/%C3%80cid_valproic" title="Àcid valproic">Àcid valproic</a></li> <li><a href="/wiki/Metotrexat" title="Metotrexat">Metotrexat</a></li> <li><a href="/w/index.php?title=Carboplat%C3%AD&amp;action=edit&amp;redlink=1" class="new" title="Carboplatí (encara no existeix)">Carboplatí</a></li> <li><a href="/wiki/Interfer%C3%B3" title="Interferó">Interferó</a></li> <li><a href="/w/index.php?title=Isotretino%C3%AFna&amp;action=edit&amp;redlink=1" class="new" title="Isotretinoïna (encara no existeix)">Isotretinoïna</a></li> <li><a href="/w/index.php?title=Panobinostat&amp;action=edit&amp;redlink=1" class="new" title="Panobinostat (encara no existeix)">Panobinostat</a></li> <li>Altres fàrmacs de <a href="/wiki/Quimioter%C3%A0pia" title="Quimioteràpia">quimioteràpia</a></li> <li>Singulair (montelukast sodium)<sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">&#91;</span>6<span class="cite-bracket">&#93;</span></a></sup></li> <li>Els <a href="/wiki/Antagonista_dels_receptors_H2" title="Antagonista dels receptors H2">antagonistes H₂</a> i <a href="/wiki/Inhibidor_de_la_bomba_de_protons" title="Inhibidor de la bomba de protons">Inhibidors de la bomba de protons</a> han mostrat símptomes de trombocitopènia augmentats, com punts vermells prop de la part baixa de les cames.<sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">&#91;</span>7<span class="cite-bracket">&#93;</span></a></sup></li></ul></li></ul> <ul><li><b>Destrucció immunològica de plaquetes:</b> <ul><li>Una molècula de fàrmac s'uneix a la porció <a href="/wiki/Fab" class="mw-redirect" title="Fab">Fab</a> d'un <a href="/wiki/Antic%C3%B2s" title="Anticòs">anticòs</a>. Un exemple clàssic és el grup de la <a href="/wiki/Quinidina" title="Quinidina">quinidina</a>. La porció Fc de l'anticòs no està implicada en el procés d'unió.</li> <li>Una molècula de fàrmac s'uneix al fragment Fc de l'anticòs, amb el complex de fàrmac/anticòs que posteriorment s'uneix i que activa les plaquetes. <a href="/wiki/Trombocitop%C3%A8nia_indu%C3%AFda_per_heparina" title="Trombocitopènia induïda per heparina">Trombocitopènia induïda per heparina</a> (TIH) és un exemple típic en que el complex <a href="/w/index.php?title=Factor_4&amp;action=edit&amp;redlink=1" class="new" title="Factor 4 (encara no existeix)">factor 4</a> <a href="/wiki/Heparina" title="Heparina">heparina</a>-anticòs-plaqueta (PF4) s'uneix als receptors Fc a la superfície de la plaqueta. Ja que el fragment Fc llavors no és disponible als receptors Fc de les cèl·lules reticuloendotelials, normalment és evitada la destrucció de les plaquetes. Això pot explicar per què la trombocitopènia severa no és un tret comú de TIH.</li> <li>Trombocitopènia provocada per <a href="/w/index.php?title=Abciximab&amp;action=edit&amp;redlink=1" class="new" title="Abciximab (encara no existeix)">abciximab</a>.</li></ul></li></ul> <div class="mw-heading mw-heading3"><h3 id="Altres_causes">Altres causes</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Trombocitop%C3%A8nia&amp;action=edit&amp;section=6" title="Modifica la secció: Altres causes"><span>modifica</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li>Mossegades de serps verinoses, especialment per <a href="/wiki/Cr%C3%B2tal" title="Cròtal">cròtals</a>.<sup id="cite_ref-fujita2005_8-0" class="reference"><a href="#cite_note-fujita2005-8"><span class="cite-bracket">&#91;</span>8<span class="cite-bracket">&#93;</span></a></sup></li> <li><a href="/w/index.php?title=Onyalai&amp;action=edit&amp;redlink=1" class="new" title="Onyalai (encara no existeix)">Onyalai</a>, una malaltia d'<a href="/wiki/Etiologia" title="Etiologia">etiologia</a> desconeguda vista només en parts de l'Àfrica, però considerada sospitosa de ser provocada per <a href="/wiki/Desnutrici%C3%B3" class="mw-redirect" title="Desnutrició">desnutrició</a> o consum de menjar contaminat.<sup id="cite_ref-Onyalai_9-0" class="reference"><a href="#cite_note-Onyalai-9"><span class="cite-bracket">&#91;</span>9<span class="cite-bracket">&#93;</span></a></sup></li> <li>Consum excessiu d'olis que contenen <a href="/wiki/%C3%80cid_er%C3%BAcic" title="Àcid erúcic">àcid erúcic</a>, com l'<a href="/wiki/Oli_de_Lorenzo" title="Oli de Lorenzo">oli de Lorenzo</a> o l'<a href="/w/index.php?title=Oli_de_mostassa&amp;action=edit&amp;redlink=1" class="new" title="Oli de mostassa (encara no existeix)">oli de mostassa</a>.</li></ul> <div class="mw-heading mw-heading2"><h2 id="Diagnosi">Diagnosi</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Trombocitop%C3%A8nia&amp;action=edit&amp;section=7" title="Modifica la secció: Diagnosi"><span>modifica</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Les proves de laboratori poden incloure: <a href="/wiki/Hemograma" title="Hemograma">hemograma</a>, <a href="/w/index.php?title=Enzim_hep%C3%A0tic&amp;action=edit&amp;redlink=1" class="new" title="Enzim hepàtic (encara no existeix)">enzims hepàtics</a>, <a href="/wiki/Funci%C3%B3_renal" class="mw-redirect" title="Funció renal">funció renal</a>, nivells de <a href="/wiki/Vitamina_B%E2%82%81%E2%82%82" title="Vitamina B₁₂">vitamina&#160;B₁₂</a>, nivells d'<a href="/wiki/%C3%80cid_f%C3%B2lic" title="Àcid fòlic">àcid fòlic</a>, <a href="/wiki/Velocitat_de_sedimentaci%C3%B3_globular" title="Velocitat de sedimentació globular">velocitat de sedimentació globular</a>, i <a href="/w/index.php?title=Frotis&amp;action=edit&amp;redlink=1" class="new" title="Frotis (encara no existeix)">frotis</a> sanguini perifèric. Si la causa pel recompte de plaquetes baix no s'aclareix, normalment es recomana una <a href="/wiki/Bi%C3%B2psia" title="Biòpsia">biòpsia</a> de <a href="/wiki/Medul%C2%B7la_%C3%B2ssia" title="Medul·la òssia">medul·la òssia</a>, per distingir si el recompte de plaquetes baix és a causa de producció disminuïda o de destrucció perifèrica. </p><p>La trombocitopènia en alcohòlics hospitalitzats pot ser provocada per <a href="/wiki/Esplenomeg%C3%A0lia" title="Esplenomegàlia">esplenomegàlia</a>, <a href="/wiki/Defici%C3%A8ncia_de_folat" class="mw-redirect" title="Deficiència de folat">deficiència de folat</a>, i, més freqüentment, un efecte tòxic directe d'alcohol sobre la producció, temps de supervivència, i funció de les plaquetes. El recompte de plaquetes es comença a créixer després de l'<a href="/wiki/Abstin%C3%A8ncia" title="Abstinència">abstinència</a> d'alcohol de 2 a 5 dies. La condició és generalment benigna, i l'hemorràgia clínicament significativa és rara. </p><p>També es poden efectuar proves de laboratori per determinar la quantitat de plaquetes i la funció de <a href="/wiki/Coagulaci%C3%B3" title="Coagulació">coagulació</a>. En la trombocitopènia severa, un estudi de medul·la òssia pot determinar el número, mida i maduresa dels <a href="/wiki/Megacari%C3%B2cit" title="Megacariòcit">megacariòcits</a> (les cèl·lules de medul·la òssia que alliberen plaquetes madures). Aquesta informació pot alhora identificar una producció de plaquetes ineficaç com la causa de trombocitopènia i excloure un procés de malaltia maligna. </p> <div class="mw-heading mw-heading2"><h2 id="Tractament">Tractament</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Trombocitop%C3%A8nia&amp;action=edit&amp;section=8" title="Modifica la secció: Tractament"><span>modifica</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>El tractament és condicionat per la severitat d'etiologia i malaltia. La idea principal en tractar la trombocitopènia és eliminar la causa subjacent, tant si significa eliminar el consum de fàrmacs/drogues sospitoses que provoquen trombocitopènia, o tractar la <a href="/wiki/Infecci%C3%B3" title="Infecció">infecció</a> subjacent. La diagnosi i el tractament de la trombocitopènia greu és normalment supervisat per un <a href="/wiki/Hematologia" title="Hematologia">hematòleg</a>. </p><p>Es poden utilitzar <a href="/wiki/Corticoide" class="mw-redirect" title="Corticoide">corticoesteroides</a> per augmentar la producció de plaquetes. El <a href="/wiki/Carbonat_de_liti" title="Carbonat de liti">carbonat de liti</a> o el <a href="/wiki/Folat" class="mw-redirect" title="Folat">folat</a> també es poden utilitzar per estimular la producció de plaquetes per la medul·la òssia. Les <a href="/wiki/Transfusi%C3%B3" class="mw-redirect" title="Transfusió">transfusions</a> de plaquetes es poden utilitzar per aturar una hemorràgia anormal episòdica provocada per un recompte de plaquetes baix. Tanmateix, si la destrucció de plaquetes és degut a un <a href="/wiki/Malaltia_autoimmunit%C3%A0ria" title="Malaltia autoimmunitària">trastorn immune</a>, les infusions de plaquetes poden tenir només un efecte mínim i es poden reservar per a hemorràgies que amenacin la vida del malalt. </p><p>Els plans de tractament específics sovint depenen de l'<a href="/wiki/Etiologia" title="Etiologia">etiologia</a> subjacent de la trombocitopènia. </p> <table class="wikitable"> <tbody><tr> <th>Condició mèdica </th> <th>Tractament </th></tr> <tr> <td><b><a href="/wiki/P%C3%BArpura_trombocitop%C3%A8nica_tromb%C3%B2tica" title="Púrpura trombocitopènica trombòtica">Púrpura trombocitopènica trombòtica</a></b> </td> <td>El tractament de <a href="/wiki/P%C3%BArpura_trombocitop%C3%A8nica_tromb%C3%B2tica" title="Púrpura trombocitopènica trombòtica">púrpura trombocitopènica trombòtica</a> és una emergència mèdica, des de l'<a href="/wiki/An%C3%A8mia_hemol%C3%ADtica" title="Anèmia hemolítica">anèmia hemolítica</a> i plaqueta l'activació pot conduir a la <a href="/wiki/Insufici%C3%A8ncia_renal" title="Insuficiència renal">insuficiència renal</a> i canvia en el nivell de consciència. El tractament de la <a href="/wiki/P%C3%BArpura_trombocitop%C3%A8nica_tromb%C3%B2tica" title="Púrpura trombocitopènica trombòtica">púrpura trombocitopènica trombòtica</a> es revolucionà durant els anys 1980 amb l'aplicació de la <a href="/wiki/Plasmaf%C3%A8resi" title="Plasmafèresi">plasmafèresi</a>. Segons la <a href="/w/index.php?title=Hip%C3%B2tesi_de_Furlan-Tsai&amp;action=edit&amp;redlink=1" class="new" title="Hipòtesi de Furlan-Tsai (encara no existeix)">hipòtesi de Furlan-Tsai</a>,<sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">&#91;</span>10<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-11" class="reference"><a href="#cite_note-11"><span class="cite-bracket">&#91;</span>11<span class="cite-bracket">&#93;</span></a></sup> <p>aquest tractament teòricament opera eliminant <a href="/wiki/Antic%C3%B2s" title="Anticòs">anticossos</a> contra el <a href="/wiki/Factor_de_von_Willebrand" title="Factor de von Willebrand">factor de von Willebrand</a> que trencava la <a href="/wiki/Peptidasa" title="Peptidasa">peptidasa</a>, <a href="/w/index.php?title=ADAMTS13&amp;action=edit&amp;redlink=1" class="new" title="ADAMTS13 (encara no existeix)">ADAMTS13</a>. El procediment de plasmafèresi també afegeix proteases <a href="/wiki/Prote%C3%AFnes" class="mw-redirect" title="Proteïnes">proteïnes</a> d'ADAMTS13 actives al pacient, restaurant un nivell fisiològic de multimers de factor de von Willebrand. Els pacients amb anticossos persistents contra ADAMTS13 no manifesten sempre púrpura trombocitopènica trombòtica, i aquests anticossos sols no són suficients per explicar com la plasmafèresi tracta la púrpura trombocitopènica trombòtica. </p><p><br /> </p> </td></tr> <tr> <td><b><a href="/wiki/P%C3%BArpura_trombocitop%C3%A8nica_idiop%C3%A0tica" title="Púrpura trombocitopènica idiopàtica">Púrpura trombocitopènica idiopàtica</a></b> (PTI) </td> <td>Molts casos de PTI poden restar sense tractament, i la remissió espontània (especialment en nens) no és inusual. Tanmateix, recomptes menors de 50.000 són normalment controlats amb anàlisis de sang regulars, i aquells amb recomptes menors de 10.000 són normalment tractats, com el risc d'hemorràgia espontània seriosa és alt amb un recompte de plaquetes baix. Qualsevol pacient que experimenta símptomes d'hemorràgia severs està també normalment tractat. El llindar per tractar PTI ha disminuït des dels anys 1990, i <a href="/wiki/Hematologia" title="Hematologia">hematòlegs</a> reconeix que els pacients rarament espontàniament sagnen amb recomptes de plaquetes més grans de 10.000—; tot i que s'han documentats excepcions a aquesta observació. <p>Els tractaments per a PTI inclouen: </p> <ul><li><a href="/wiki/Prednisona" title="Prednisona">Prednisona</a> i altres <a href="/wiki/Corticoide" class="mw-redirect" title="Corticoide">corticoesteroides</a></li> <li><a href="/w/index.php?title=Immunoglobulina_intravenosa&amp;action=edit&amp;redlink=1" class="new" title="Immunoglobulina intravenosa (encara no existeix)">immunoglobulina intravenosa</a></li> <li><a href="/wiki/Esplenectomia" title="Esplenectomia">Esplenectomia</a></li> <li><a href="/w/index.php?title=Danazol&amp;action=edit&amp;redlink=1" class="new" title="Danazol (encara no existeix)">Danazol</a></li> <li><a href="/w/index.php?title=Eltrombopag&amp;action=edit&amp;redlink=1" class="new" title="Eltrombopag (encara no existeix)">Eltrombopag</a></li> <li><a href="/wiki/Rituximab" title="Rituximab">Rituximab</a></li> <li><a href="/w/index.php?title=Romiplostim&amp;action=edit&amp;redlink=1" class="new" title="Romiplostim (encara no existeix)">Romiplostim</a></li></ul> <p>Els anàlegs de <a href="/wiki/Trombopoetina" title="Trombopoetina">trombopoetina</a> s'han provat extensament per al tractament de PTI. Aquests agents havien mostrat prèviament una certa activitat però s'havia trobat que estimulaven anticossos contra trombopoetina endògena o provocaven <a href="/wiki/Trombosi" title="Trombosi">trombosi</a>. </p><p>S'ha determinat que Romiplostim (nom comercial Nplate, anteriorment AMG 531) és segur i eficaç per al tractament de PTI en pacients refractaris, especialment els que requeien després de l'esplenectomia.<sup id="cite_ref-12" class="reference"><a href="#cite_note-12"><span class="cite-bracket">&#91;</span>12<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-13" class="reference"><a href="#cite_note-13"><span class="cite-bracket">&#91;</span>13<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-14" class="reference"><a href="#cite_note-14"><span class="cite-bracket">&#91;</span>14<span class="cite-bracket">&#93;</span></a></sup> </p> </td></tr> <tr> <td><b><a href="/wiki/Trombocitop%C3%A8nia_indu%C3%AFda_per_heparina" title="Trombocitopènia induïda per heparina">Trombocitopènia induïda per heparina</a></b> (TIH) </td> <td>La discontinuació d'heparina és crítica en casos de TIH. Tanmateix, els clínics generalment tracten per evitar una trombosi, i els pacients inicien directament un tractament de <a href="/wiki/Warfarina" title="Warfarina">warfarina</a> després d'una diagnosi de TIH són a risc excessiu de <a href="/wiki/Gangrena" title="Gangrena">gangrena</a> venosa de membre. Per aquesta raó, tracta normalment pacients amb un tipus d'<a href="/wiki/Anticoagulant" title="Anticoagulant">anticoagulant</a> anomenat <a href="/w/index.php?title=Inhibidor_directe_de_trombina&amp;action=edit&amp;redlink=1" class="new" title="Inhibidor directe de trombina (encara no existeix)">inhibidor directe de trombina</a> com la <a href="/w/index.php?title=Lepirudina&amp;action=edit&amp;redlink=1" class="new" title="Lepirudina (encara no existeix)">lepirudina</a> o l'<a href="/w/index.php?title=Argatroban&amp;action=edit&amp;redlink=1" class="new" title="Argatroban (encara no existeix)">argatroban</a>, aprovat per l'<a href="/wiki/Administraci%C3%B3_d%27Aliments_i_F%C3%A0rmacs" title="Administració d&#39;Aliments i Fàrmacs">Administració d'Aliments i Fàrmacs</a> (FDA). Altres <a href="/wiki/Anticoagulants" class="mw-redirect" title="Anticoagulants">anticoagulants</a> a vegades utilitzats en aquests casos que no són aprovats la FDA per al tractament de TIH inclou <a href="/w/index.php?title=Bivalirudina&amp;action=edit&amp;redlink=1" class="new" title="Bivalirudina (encara no existeix)">bivalirudina</a> i <a href="/w/index.php?title=Fondaparinux&amp;action=edit&amp;redlink=1" class="new" title="Fondaparinux (encara no existeix)">fondaparinux</a>. Les <a href="/wiki/Transfusi%C3%B3_de_plaquetes" title="Transfusió de plaquetes">transfusions de plaquetes</a> no són un component rutinari del tractament de TIH, ja que la trombosi, que no sagna, és el problema associat habitual en aquesta malaltia. </td></tr> <tr> <td><b><a href="/w/index.php?title=Trombocitop%C3%A8nia_amegacarioc%C3%ADtica_cong%C3%A8nita&amp;action=edit&amp;redlink=1" class="new" title="Trombocitopènia amegacariocítica congènita (encara no existeix)">Trombocitopènia amegacariocítica congènita</a></b> </td> <td>El trasplantament de medul·la òssia o cèl·lula mares és l'únic tractament que realment cura aquesta <a href="/wiki/Malaltia_gen%C3%A8tica" class="mw-redirect" title="Malaltia genètica">malaltia genètica</a>. S'exigeix que les transfusions de plaquetes freqüents impedeixin al pacient dessagnar-se fins que el trasplantament es realitzi, encara que això no és sempre el cas. </td></tr></tbody></table> <div class="mw-heading mw-heading2"><h2 id="Trombocitopènia_neonatal"><span id="Trombocitop.C3.A8nia_neonatal"></span>Trombocitopènia neonatal</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Trombocitop%C3%A8nia&amp;action=edit&amp;section=9" title="Modifica la secció: Trombocitopènia neonatal"><span>modifica</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>La trombocitopènia afecta un petit percentatge de nadons, i la seva <a href="/wiki/Prevalen%C3%A7a" title="Prevalença">prevalença</a> en unitats de vigilància intensiva neonatal és alta. Normalment, el seu curs és suau i es resol sense conseqüències. La majoria dels casos de trombocitopènia afecten infants de <a href="/wiki/Part_preterme" title="Part preterme">naixement preterme</a> i són resultats d'insuficiència placental i/o hipòxia fetal. Altres causes són menys freqüents, p. ex. alloimmune, genètic, autoimmune, infecció, DIC.<sup id="cite_ref-pmid12937037_15-0" class="reference"><a href="#cite_note-pmid12937037-15"><span class="cite-bracket">&#91;</span>15<span class="cite-bracket">&#93;</span></a></sup> </p><p>La trombocitopènia iniciada després de les primeres 72 hores després del naixement sovint és el resultat de <a href="/wiki/S%C3%A8psia" title="Sèpsia">sèpsia</a> subjacent o <a href="/wiki/Enterocolitis_necrosant" title="Enterocolitis necrosant">enterocolitis necrosant</a>.<sup id="cite_ref-pmid12937037_15-1" class="reference"><a href="#cite_note-pmid12937037-15"><span class="cite-bracket">&#91;</span>15<span class="cite-bracket">&#93;</span></a></sup> En termes d'infecció les proves de <a href="/wiki/Reacci%C3%B3_en_cadena_de_la_polimerasa" title="Reacció en cadena de la polimerasa">PCR</a> poden ser útils per a la identificació patògena ràpida i detecció de gens de resistència d'antibiòtics. Els patògens possibles poden ser fong, bacteris i virus, per exemple: <a href="/wiki/Citomegalovirus" title="Citomegalovirus">Citomegalovirus</a> (CMV),<sup id="cite_ref-pmid12937037_15-2" class="reference"><a href="#cite_note-pmid12937037-15"><span class="cite-bracket">&#91;</span>15<span class="cite-bracket">&#93;</span></a></sup> <a href="/wiki/Rubivirus" title="Rubivirus">Virus de rubèola</a>,<sup id="cite_ref-pmid12937037_15-3" class="reference"><a href="#cite_note-pmid12937037-15"><span class="cite-bracket">&#91;</span>15<span class="cite-bracket">&#93;</span></a></sup> <a href="/wiki/Virus_de_la_immunodefici%C3%A8ncia_humana" title="Virus de la immunodeficiència humana">virus de la immunodeficiència humana</a>,<sup id="cite_ref-pmid12937037_15-4" class="reference"><a href="#cite_note-pmid12937037-15"><span class="cite-bracket">&#91;</span>15<span class="cite-bracket">&#93;</span></a></sup> <a href="/wiki/Estafilococ" title="Estafilococ"><i>Staphylococcus sp</i>.</a>,<sup id="cite_ref-pmid12777561_16-0" class="reference"><a href="#cite_note-pmid12777561-16"><span class="cite-bracket">&#91;</span>16<span class="cite-bracket">&#93;</span></a></sup> <a href="/wiki/Enterococ" title="Enterococ">Enterococcus sp.</a>,<sup id="cite_ref-pmid12777561_16-1" class="reference"><a href="#cite_note-pmid12777561-16"><span class="cite-bracket">&#91;</span>16<span class="cite-bracket">&#93;</span></a></sup> <i><a href="/wiki/Streptococcus_agalactiae" title="Streptococcus agalactiae">Streptococcus agalactiae</a>,</i><sup id="cite_ref-pmid12937037_15-5" class="reference"><a href="#cite_note-pmid12937037-15"><span class="cite-bracket">&#91;</span>15<span class="cite-bracket">&#93;</span></a></sup> <i><a href="/wiki/Streptococcus_viridans" title="Streptococcus viridans">Streptococcus viridans</a>,</i><sup id="cite_ref-Joklein_17-0" class="reference"><a href="#cite_note-Joklein-17"><span class="cite-bracket">&#91;</span>17<span class="cite-bracket">&#93;</span></a></sup> <i><a href="/wiki/Listeria_monocytogenes" class="mw-redirect" title="Listeria monocytogenes">Listeria monocytogenes</a>,</i><sup id="cite_ref-Ddzierzanowska_18-0" class="reference"><a href="#cite_note-Ddzierzanowska-18"><span class="cite-bracket">&#91;</span>18<span class="cite-bracket">&#93;</span></a></sup> <i><a href="/wiki/Escherichia_coli" class="mw-redirect" title="Escherichia coli">Escherichia coli</a>,</i><sup id="cite_ref-pmid12937037_15-6" class="reference"><a href="#cite_note-pmid12937037-15"><span class="cite-bracket">&#91;</span>15<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-pmid12777561_16-2" class="reference"><a href="#cite_note-pmid12777561-16"><span class="cite-bracket">&#91;</span>16<span class="cite-bracket">&#93;</span></a></sup> <i><a href="/wiki/Haemophilus_influenzae" title="Haemophilus influenzae">Haemophilus influenzae</a>,</i><sup id="cite_ref-pmid12937037_15-7" class="reference"><a href="#cite_note-pmid12937037-15"><span class="cite-bracket">&#91;</span>15<span class="cite-bracket">&#93;</span></a></sup> <i><a href="/wiki/Klebsiella_pneumoniae" class="mw-redirect" title="Klebsiella pneumoniae">Klebsiella pneumoniae</a>,</i><sup id="cite_ref-pmid12777561_16-3" class="reference"><a href="#cite_note-pmid12777561-16"><span class="cite-bracket">&#91;</span>16<span class="cite-bracket">&#93;</span></a></sup> <i><a href="/wiki/Pseudomonas_aeruginosa" title="Pseudomonas aeruginosa">Pseudomonas aeruginosa</a>,</i><sup id="cite_ref-pmid12777561_16-4" class="reference"><a href="#cite_note-pmid12777561-16"><span class="cite-bracket">&#91;</span>16<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-pmid3569360_19-0" class="reference"><a href="#cite_note-pmid3569360-19"><span class="cite-bracket">&#91;</span>19<span class="cite-bracket">&#93;</span></a></sup> <i><a href="/wiki/Yersinia_enterocolitica" title="Yersinia enterocolitica">Yersinia enterocolitica</a>,</i><sup id="cite_ref-pmid3569360_19-1" class="reference"><a href="#cite_note-pmid3569360-19"><span class="cite-bracket">&#91;</span>19<span class="cite-bracket">&#93;</span></a></sup> <i><a href="/wiki/Borrelia_burgdorferi" title="Borrelia burgdorferi">Borrelia burgdorferi</a>,</i><sup id="cite_ref-Joklein_17-1" class="reference"><a href="#cite_note-Joklein-17"><span class="cite-bracket">&#91;</span>17<span class="cite-bracket">&#93;</span></a></sup> <i><a href="/wiki/Candida" title="Candida">Candida</a> sp</i>.,<sup id="cite_ref-pmid12777561_16-5" class="reference"><a href="#cite_note-pmid12777561-16"><span class="cite-bracket">&#91;</span>16<span class="cite-bracket">&#93;</span></a></sup> <i><a href="/wiki/Toxoplasma_gondii" title="Toxoplasma gondii">Toxoplasma gondii</a></i>.<sup id="cite_ref-pmid12937037_15-8" class="reference"><a href="#cite_note-pmid12937037-15"><span class="cite-bracket">&#91;</span>15<span class="cite-bracket">&#93;</span></a></sup> La severitat de la trombocitopènia es podria correlacionar amb el tipus de patogen; algunes recerques indiquen que els casos més severs es relacionen a la infecció micòtica o per bacteris <a href="/wiki/Gramnegatiu" class="mw-redirect" title="Gramnegatiu">gramnegatius</a>.<sup id="cite_ref-pmid12777561_16-6" class="reference"><a href="#cite_note-pmid12777561-16"><span class="cite-bracket">&#91;</span>16<span class="cite-bracket">&#93;</span></a></sup> El patogen es pot transmetre durant el naixement<sup id="cite_ref-pmid13324978_20-0" class="reference"><a href="#cite_note-pmid13324978-20"><span class="cite-bracket">&#91;</span>20<span class="cite-bracket">&#93;</span></a></sup> o abans d'aquest, però també durant l'<a href="/wiki/Alletament" class="mw-redirect" title="Alletament">alletament</a>.<sup id="cite_ref-pmid10873172_21-0" class="reference"><a href="#cite_note-pmid10873172-21"><span class="cite-bracket">&#91;</span>21<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-pmid12687430_22-0" class="reference"><a href="#cite_note-pmid12687430-22"><span class="cite-bracket">&#91;</span>22<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-pmid16371885_23-0" class="reference"><a href="#cite_note-pmid16371885-23"><span class="cite-bracket">&#91;</span>23<span class="cite-bracket">&#93;</span></a></sup> o durant una transfusió.<sup id="cite_ref-Mjagielski_24-0" class="reference"><a href="#cite_note-Mjagielski-24"><span class="cite-bracket">&#91;</span>24<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Pmielczarek_25-0" class="reference"><a href="#cite_note-Pmielczarek-25"><span class="cite-bracket">&#91;</span>25<span class="cite-bracket">&#93;</span></a></sup> S'està investigant la <a href="/wiki/Interleucina" title="Interleucina">interleucina</a>-11 com a potencial fàrmac per al tractament de la trombocitopènia, especialment en els casos de <a href="/wiki/S%C3%A8psia" title="Sèpsia">sèpsia</a> o <a href="/wiki/Enterocolitis_necrosant" title="Enterocolitis necrosant">enterocolitis necrosant</a>.<sup id="cite_ref-pmid12937037_15-9" class="reference"><a href="#cite_note-pmid12937037-15"><span class="cite-bracket">&#91;</span>15<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Referències"><span id="Refer.C3.A8ncies"></span>Referències</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Trombocitop%C3%A8nia&amp;action=edit&amp;section=10" title="Modifica la secció: Referències"><span>modifica</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="reflist &#123;&#123;#if: &#124; references-column-count references-column-count-&#123;&#123;&#123;col&#125;&#125;&#125;" style="list-style-type: decimal;"> <div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-lto-1"><span class="mw-cite-backlink"><a href="#cite_ref-lto_1-0">↑</a></span> <span class="reference-text"><span class="citation" style="font-style:normal">«<a rel="nofollow" class="external text" href="http://www.labtestsonline.org.uk/understanding/analytes/platelet/test.html">Platelet count aka thrombocyte count</a>».&#32; Lab Tests Online UK,&#32;28-05-2004.</span></span> </li> <li id="cite_note-pmid19118853-2"><span class="mw-cite-backlink"><a href="#cite_ref-pmid19118853_2-0">↑</a></span> <span class="reference-text"><span class="citation" style="font-style:normal" id="CITEREFCorreiaDominguesLacerdaSantos2009"><span style="font-variant: small-caps;">Correia</span>, Maria C.B.;&#32;<span style="font-variant: small-caps;">Domingues</span>, Ana L.C.;&#32;<span style="font-variant: small-caps;">Lacerda</span>, Heloisa R.;&#32;<span style="font-variant: small-caps;">Santos</span>, Emília M.;&#32;<span style="font-variant: small-caps;">MacHado</span>, CíNtia G.F.;&#32;<span style="font-variant: small-caps;">Hora</span>, Viviane;&#32;<span style="font-variant: small-caps;">Neves</span>, Maria A.;&#32;<span style="font-variant: small-caps;">Brito</span>, Anelita;&#32;<span style="font-variant: small-caps;">Coêlho</span>, Maria R.C.D.&#32;«Platelet function and the von Willebrand factor antigen in the hepatosplenic form of schistosomiasis mansoni».&#32;<i>Transactions of the Royal Society of Tropical Medicine and Hygiene</i>,&#32;103,&#32;10,&#32;2009,&#32;pàg.&#160;1053–8. <a href="/wiki/DOI" title="DOI">DOI</a>: <a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2Fj.trstmh.2008.11.017">10.1016/j.trstmh.2008.11.017</a>. <a href="/wiki/PubMed" title="PubMed">PMID</a>: <a href="https://www.ncbi.nlm.nih.gov/pubmed/19118853?dopt=Abstract" class="extiw" title="pmid:19118853">19118853</a>.</span></span> </li> <li id="cite_note-pmid15896582-3"><span class="mw-cite-backlink"><a href="#cite_ref-pmid15896582_3-0">↑</a></span> <span class="reference-text"><span class="citation" style="font-style:normal" id="CITEREFCheungMcAuleyPollard2005"><span style="font-variant: small-caps;">Cheung</span>, R;&#32;<span style="font-variant: small-caps;">McAuley</span>, R;&#32;<span style="font-variant: small-caps;">Pollard</span>, J&#32;«High mortality rate in patients with advanced liver disease independent of exposure to general anesthesia».&#32;<i>Journal of Clinical Anesthesia</i>,&#32;17,&#32;3,&#32;2005,&#32;pàg.&#160;172–6. <a href="/wiki/DOI" title="DOI">DOI</a>: <a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2Fj.jclinane.2004.06.016">10.1016/j.jclinane.2004.06.016</a>. <a href="/wiki/PubMed" title="PubMed">PMID</a>: <a href="https://www.ncbi.nlm.nih.gov/pubmed/15896582?dopt=Abstract" class="extiw" title="pmid:15896582">15896582</a>.</span></span> </li> <li id="cite_note-pmid11914001-4"><span class="mw-cite-backlink"><a href="#cite_ref-pmid11914001_4-0">↑</a></span> <span class="reference-text"><span class="citation" style="font-style:normal" id="CITEREFScaradavou2002"><span style="font-variant: small-caps;">Scaradavou</span>, A&#32;«HIV-related thrombocytopenia».&#32;<i>Blood Reviews</i>,&#32;16,&#32;1,&#32;2002,&#32;pàg.&#160;73–6. <a href="/wiki/DOI" title="DOI">DOI</a>: <a rel="nofollow" class="external text" href="https://dx.doi.org/10.1054%2Fblre.2001.0188">10.1054/blre.2001.0188</a>. <a href="/wiki/PubMed" title="PubMed">PMID</a>: <a href="https://www.ncbi.nlm.nih.gov/pubmed/11914001?dopt=Abstract" class="extiw" title="pmid:11914001">11914001</a>.</span></span> </li> <li id="cite_note-urlmoon.ouhsc.edu-5"><span class="mw-cite-backlink"><a href="#cite_ref-urlmoon.ouhsc.edu_5-0">↑</a></span> <span class="reference-text"><span class="citation" style="font-style:normal">«<a rel="nofollow" class="external text" href="https://web.archive.org/web/20110928073444/http://moon.ouhsc.edu/jgeorge/drug%20ITP_single04.htm">moon.ouhsc.edu</a>». Arxivat de l'<a rel="nofollow" class="external text" href="http://moon.ouhsc.edu/jgeorge/drug%20ITP_single04.htm">original</a> el 2011-09-28.&#32;[Consulta: 20 abril 2012].</span> disposa de més fàrmacs productors de trombocitopènia</span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><a href="#cite_ref-6">↑</a></span> <span class="reference-text"><sup title="Cal donar format a aquesta referència." class="noprint"><span class="noprint" style="color:blue;"><i>&#91;<a href="/wiki/VP:REF" class="mw-redirect" title="VP:REF">enllaç sense format</a>&#93;</i></span></sup> <a rel="nofollow" class="external free" href="http://www.fda.gov/Safety/MedWatch/SafetyInformation/Safety-RelatedDrugLabelingChanges/ucm117838.htm">http://www.fda.gov/Safety/MedWatch/SafetyInformation/Safety-RelatedDrugLabelingChanges/ucm117838.htm</a></span> </li> <li id="cite_note-7"><span class="mw-cite-backlink"><a href="#cite_ref-7">↑</a></span> <span class="reference-text"><span class="citation" style="font-style:normal" id="CITEREFWatsonStarkVesta2006"><span style="font-variant: small-caps;">Watson</span>, T. D;&#32;<span style="font-variant: small-caps;">Stark</span>, JE;&#32;<span style="font-variant: small-caps;">Vesta</span>, KS&#32;«Pantoprazole-Induced Thrombocytopenia».&#32;<i>Annals of Pharmacotherapy</i>,&#32;40,&#32;4,&#32;2006,&#32;pàg.&#160;758–61. <a href="/wiki/DOI" title="DOI">DOI</a>: <a rel="nofollow" class="external text" href="https://dx.doi.org/10.1345%2Faph.1G384">10.1345/aph.1G384</a>. <a href="/wiki/PubMed" title="PubMed">PMID</a>: <a href="https://www.ncbi.nlm.nih.gov/pubmed/16569810?dopt=Abstract" class="extiw" title="pmid:16569810">16569810</a>.</span></span> </li> <li id="cite_note-fujita2005-8"><span class="mw-cite-backlink"><a href="#cite_ref-fujita2005_8-0">↑</a></span> <span class="reference-text"><span class="citation" style="font-style:normal" id="CITEREFMotokiSusumuNobukatsuRyosuke2005"><span style="font-variant: small-caps;">Motoki</span>, Fijita;&#32;<span style="font-variant: small-caps;">Susumu</span>, Yamashita;&#32;<span style="font-variant: small-caps;">Nobukatsu</span>, Kawamura;&#32;<span style="font-variant: small-caps;">Ryosuke</span>, Tsuruta;&#32;<span style="font-variant: small-caps;">Shunji</span>, Kasaoka;&#32;<span style="font-variant: small-caps;">Kiyoshi</span>, Okabayashi;&#32;<span style="font-variant: small-caps;">Tsuyoshi</span>, Maekawa&#32;«Viper (Agkistrodon halys blomhoffii 'Mamushi') Bite with Remarkable Thrombocytopenia».&#32;<i>Journal of Japanese Association for Acute Medicine</i>,&#32;16,&#32;3,&#32;2005,&#32;pàg.&#160;126–30. <a href="/wiki/DOI" title="DOI">DOI</a>: <a rel="nofollow" class="external text" href="https://dx.doi.org/10.3893%2Fjjaam.16.126">10.3893/jjaam.16.126</a>. <a href="/wiki/ISSN" title="ISSN">ISSN</a>: <a rel="nofollow" class="external text" href="//www.worldcat.org/issn/0915-924X">0915-924X</a>.</span></span> </li> <li id="cite_note-Onyalai-9"><span class="mw-cite-backlink"><a href="#cite_ref-Onyalai_9-0">↑</a></span> <span class="reference-text"><span class="citation" style="font-style:normal">«<a rel="nofollow" class="external text" href="http://www.itg.be/evde/45_Haematologyp6.htm">Onyalai</a>».</span><sup class="noprint Inline-Template"><span title="" style="white-space: nowrap;"><i>&#91;<a href="/wiki/Viquip%C3%A8dia:Enlla%C3%A7os_externs#Manteniment_d&#39;enllaços_externs" title="Viquipèdia:Enllaços externs">Enllaç no actiu</a>&#93;</i></span></sup></span> </li> <li id="cite_note-10"><span class="mw-cite-backlink"><a href="#cite_ref-10">↑</a></span> <span class="reference-text"><span class="citation" style="font-style:normal" id="CITEREFFurlan2001"><span style="font-variant: small-caps;">Furlan</span>, M&#32;«Aetiology and pathogenesis of thrombotic thrombocytopenic purpura and haemolytic uraemic syndrome: the role of von Willebrand factor-cleaving protease».&#32;<i>Best Practice &amp; Research Clinical Haematology</i>,&#32;14,&#32;2,&#32;2001,&#32;pàg.&#160;437–54. <a href="/wiki/DOI" title="DOI">DOI</a>: <a rel="nofollow" class="external text" href="https://dx.doi.org/10.1053%2Fbeha.2001.0142">10.1053/beha.2001.0142</a>. <a href="/wiki/PubMed" title="PubMed">PMID</a>: <a href="https://www.ncbi.nlm.nih.gov/pubmed/11686108?dopt=Abstract" class="extiw" title="pmid:11686108">11686108</a>.</span></span> </li> <li id="cite_note-11"><span class="mw-cite-backlink"><a href="#cite_ref-11">↑</a></span> <span class="reference-text"><span class="citation" style="font-style:normal" id="CITEREFTsai2003"><span style="font-variant: small-caps;">Tsai</span>, H.-M.&#32;«Advances in the Pathogenesis, Diagnosis, and Treatment of Thrombotic Thrombocytopenic Purpura».&#32;<i>Journal of the American Society of Nephrology</i>,&#32;14,&#32;4,&#32;2003,&#32;pàg.&#160;1072–81. <a href="/wiki/DOI" title="DOI">DOI</a>: <a rel="nofollow" class="external text" href="https://dx.doi.org/10.1097%2F01.ASN.0000060805.04118.4C">10.1097/01.ASN.0000060805.04118.4C</a>. <a href="/wiki/PubMed" title="PubMed">PMID</a>: <a href="https://www.ncbi.nlm.nih.gov/pubmed/12660343?dopt=Abstract" class="extiw" title="pmid:12660343">12660343</a>.</span></span> </li> <li id="cite_note-12"><span class="mw-cite-backlink"><a href="#cite_ref-12">↑</a></span> <span class="reference-text"><span class="citation" style="font-style:normal" id="CITEREFBusselKuterGeorgeMcMillan2006"><span style="font-variant: small-caps;">Bussel</span>, James B.;&#32;<span style="font-variant: small-caps;">Kuter</span>, David J.;&#32;<span style="font-variant: small-caps;">George</span>, James N.;&#32;<span style="font-variant: small-caps;">McMillan</span>, Robert;&#32;<span style="font-variant: small-caps;">Aledort</span>, Louis M.;&#32;<span style="font-variant: small-caps;">Conklin</span>, George T.;&#32;<span style="font-variant: small-caps;">Lichtin</span>, Alan E.;&#32;<span style="font-variant: small-caps;">Lyons</span>, Roger M.;&#32;<span style="font-variant: small-caps;">Nieva</span>, Jorge&#32;«AMG 531, a Thrombopoiesis-Stimulating Protein, for Chronic ITP».&#32;<i>New England Journal of Medicine</i>,&#32;355,&#32;16,&#32;2006,&#32;pàg.&#160;1672–81. <a href="/wiki/DOI" title="DOI">DOI</a>: <a rel="nofollow" class="external text" href="https://dx.doi.org/10.1056%2FNEJMoa054626">10.1056/NEJMoa054626</a>. <a href="/wiki/PubMed" title="PubMed">PMID</a>: <a href="https://www.ncbi.nlm.nih.gov/pubmed/17050891?dopt=Abstract" class="extiw" title="pmid:17050891">17050891</a>.</span></span> </li> <li id="cite_note-13"><span class="mw-cite-backlink"><a href="#cite_ref-13">↑</a></span> <span class="reference-text"><span class="citation" style="font-style:normal">AMGEN&#32;«<a rel="nofollow" class="external text" href="https://www.drugs.com/nda/romiplostim_080313.html">Press release: Amgen Statement on Successful Outcome of Romiplostim Panel Meeting</a>».&#32;<i>Business Wire via drugs.com</i>,&#32;12-03-2008.</span></span> </li> <li id="cite_note-14"><span class="mw-cite-backlink"><a href="#cite_ref-14">↑</a></span> <span class="reference-text"><span class="citation" style="font-style:normal" id="CITEREFRichwine2008"><span style="font-variant: small-caps;">Richwine</span>, Lisa&#32;«<a rel="nofollow" class="external text" href="http://www.reuters.com/article/2008/03/12/amgen-nplate-idUSWAT00911720080312">US FDA panel backs Amgen's Nplate against ITP</a>».&#32;<i>Reuters</i>,&#32;12-03-2008&#32;[Consulta: 20 abril 2012].</span> <span class="citation" style="font-style:normal">«<a rel="nofollow" class="external text" href="https://archive.today/20130201054056/http://www.reuters.com/article/2008/03/12/amgen-nplate-idUSWAT00911720080312">Còpia arxivada</a>». Arxivat de l'<a rel="nofollow" class="external text" href="http://www.reuters.com/article/2008/03/12/amgen-nplate-idUSWAT00911720080312">original</a> el 2013-02-01.&#32;[Consulta: 20 abril 2012].</span></span> </li> <li id="cite_note-pmid12937037-15"><span class="mw-cite-backlink">↑ <sup><a href="#cite_ref-pmid12937037_15-0">15,00</a></sup> <sup><a href="#cite_ref-pmid12937037_15-1">15,01</a></sup> <sup><a href="#cite_ref-pmid12937037_15-2">15,02</a></sup> <sup><a href="#cite_ref-pmid12937037_15-3">15,03</a></sup> <sup><a href="#cite_ref-pmid12937037_15-4">15,04</a></sup> <sup><a href="#cite_ref-pmid12937037_15-5">15,05</a></sup> <sup><a href="#cite_ref-pmid12937037_15-6">15,06</a></sup> <sup><a href="#cite_ref-pmid12937037_15-7">15,07</a></sup> <sup><a href="#cite_ref-pmid12937037_15-8">15,08</a></sup> <sup><a href="#cite_ref-pmid12937037_15-9">15,09</a></sup></span> <span class="reference-text"><span class="citation" style="font-style:normal" id="CITEREFRobertsMurray2003"><span style="font-variant: small-caps;">Roberts</span>, I;&#32;<span style="font-variant: small-caps;">Murray</span>, NA&#32;«Neonatal thrombocytopenia: causes and management».&#32;<i>Archives of Disease in Childhood - Fetal and Neonatal Edition</i>,&#32;88,&#32;5,&#32;2003,&#32;pàg.&#160;F359–64. <a href="/wiki/DOI" title="DOI">DOI</a>: <a rel="nofollow" class="external text" href="https://dx.doi.org/10.1136%2Ffn.88.5.F359">10.1136/fn.88.5.F359</a>. <a href="/wiki/PubMed" title="PubMed">PMC</a>: <a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1721612">1721612</a>. <a href="/wiki/PubMed" title="PubMed">PMID</a>: <a href="https://www.ncbi.nlm.nih.gov/pubmed/12937037?dopt=Abstract" class="extiw" title="pmid:12937037">12937037</a>.</span></span> </li> <li id="cite_note-pmid12777561-16"><span class="mw-cite-backlink">↑ <sup><a href="#cite_ref-pmid12777561_16-0">16,0</a></sup> <sup><a href="#cite_ref-pmid12777561_16-1">16,1</a></sup> <sup><a href="#cite_ref-pmid12777561_16-2">16,2</a></sup> <sup><a href="#cite_ref-pmid12777561_16-3">16,3</a></sup> <sup><a href="#cite_ref-pmid12777561_16-4">16,4</a></sup> <sup><a href="#cite_ref-pmid12777561_16-5">16,5</a></sup> <sup><a href="#cite_ref-pmid12777561_16-6">16,6</a></sup></span> <span class="reference-text"><span class="citation" style="font-style:normal" id="CITEREFGuidaKunigLeefMcKenzie2003"><span style="font-variant: small-caps;">Guida</span>, JD;&#32;<span style="font-variant: small-caps;">Kunig</span>, AM;&#32;<span style="font-variant: small-caps;">Leef</span>, KH;&#32;<span style="font-variant: small-caps;">McKenzie</span>, SE;&#32;<span style="font-variant: small-caps;">Paul</span>, DA&#32;«Platelet count and sepsis in very low birth weight neonates: is there an organism-specific response?».&#32;<i>Pediatrics</i>,&#32;111,&#32;6 Pt 1,&#32;2003,&#32;pàg.&#160;1411–5. <a href="/wiki/PubMed" title="PubMed">PMID</a>: <a href="https://www.ncbi.nlm.nih.gov/pubmed/12777561?dopt=Abstract" class="extiw" title="pmid:12777561">12777561</a>.</span></span> </li> <li id="cite_note-Joklein-17"><span class="mw-cite-backlink">↑ <sup><a href="#cite_ref-Joklein_17-0">17,0</a></sup> <sup><a href="#cite_ref-Joklein_17-1">17,1</a></sup></span> <span class="reference-text"><span class="citation" style="font-style:normal" id="CITEREFKlein1990"><span style="font-variant: small-caps;">Klein</span>, JO&#32;«Bacteriology of neonatal sepsis».&#32;<i>The Pediatric Infectious Disease Journal</i>,&#32;9,&#32;10,&#32;1990,&#32;pàg.&#160;778. <a href="/wiki/PubMed" title="PubMed">PMID</a>: <a href="https://www.ncbi.nlm.nih.gov/pubmed/2235163?dopt=Abstract" class="extiw" title="pmid:2235163">2235163</a>.</span></span> </li> <li id="cite_note-Ddzierzanowska-18"><span class="mw-cite-backlink"><a href="#cite_ref-Ddzierzanowska_18-0">↑</a></span> <span class="reference-text"><span class="citation book" style="font-style:normal">D Dzierzanowska. <i>Antybiotykoterapia praktyczna</i>,&#32;2001. <span style="font-size:90%; white-space:nowrap;"><a href="/wiki/Especial:Fonts_bibliogr%C3%A0fiques/83-88778-20-X" title="Especial:Fonts bibliogràfiques/83-88778-20-X">ISBN 83-88778-20-X</a></span>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=book&amp;rft.btitle=Antybiotykoterapia+praktyczna&amp;rft.au=D+Dzierzanowska&amp;rft.date=2001&amp;rft.isbn=83-88778-20-X"><span style="display: none;">&#160;</span></span></span> </li> <li id="cite_note-pmid3569360-19"><span class="mw-cite-backlink">↑ <sup><a href="#cite_ref-pmid3569360_19-0">19,0</a></sup> <sup><a href="#cite_ref-pmid3569360_19-1">19,1</a></sup></span> <span class="reference-text"><span class="citation" style="font-style:normal" id="CITEREFPacificoChiesaMirabellaPanero1987"><span style="font-variant: small-caps;">Pacifico</span>, L;&#32;<span style="font-variant: small-caps;">Chiesa</span>, C;&#32;<span style="font-variant: small-caps;">Mirabella</span>, S;&#32;<span style="font-variant: small-caps;">Panero</span>, A;&#32;<span style="font-variant: small-caps;">Midulla</span>, M&#32;«Early-onset Pseudomonas aeruginosa sepsis and Yersinia enterocolitica neonatal infection: a unique combination in a preterm infant».&#32;<i>European journal of pediatrics</i>,&#32;146,&#32;2,&#32;1987,&#32;pàg.&#160;192–3. <a href="/wiki/PubMed" title="PubMed">PMID</a>: <a href="https://www.ncbi.nlm.nih.gov/pubmed/3569360?dopt=Abstract" class="extiw" title="pmid:3569360">3569360</a>.</span></span> </li> <li id="cite_note-pmid13324978-20"><span class="mw-cite-backlink"><a href="#cite_ref-pmid13324978_20-0">↑</a></span> <span class="reference-text"><span class="citation" style="font-style:normal" id="CITEREFRempenMartiusHartmannWecker1987"><span style="font-variant: small-caps;">Rempen</span>, A;&#32;<span style="font-variant: small-caps;">Martius</span>, J;&#32;<span style="font-variant: small-caps;">Hartmann</span>, AA;&#32;<span style="font-variant: small-caps;">Wecker</span>, I&#32;«Transmission rate of Ureaplasma urealyticum, Mycoplasma spp., Gardnerella vaginalis, B-streptococci, Candida spp. and Chlamydia trachomatis from the mother to the newborn».&#32;<i>Archives of gynecology and obstetrics</i>,&#32;241,&#32;3,&#32;1987,&#32;pàg.&#160;165–70. <a href="/wiki/PubMed" title="PubMed">PMID</a>: <a href="https://www.ncbi.nlm.nih.gov/pubmed/3324978?dopt=Abstract" class="extiw" title="pmid:3324978">3324978</a>.</span></span> </li> <li id="cite_note-pmid10873172-21"><span class="mw-cite-backlink"><a href="#cite_ref-pmid10873172_21-0">↑</a></span> <span class="reference-text"><span class="citation" style="font-style:normal" id="CITEREFOlverBondBoswellWatkin2000"><span style="font-variant: small-caps;">Olver</span>, WJ;&#32;<span style="font-variant: small-caps;">Bond</span>, DW;&#32;<span style="font-variant: small-caps;">Boswell</span>, TC;&#32;<span style="font-variant: small-caps;">Watkin</span>, SL&#32;«Neonatal group B streptococcal disease associated with infected breast milk».&#32;<i>Archives of disease in childhood. Fetal and neonatal edition</i>,&#32;83,&#32;1,&#32;2000,&#32;pàg.&#160;F48–9. <a href="/wiki/PubMed" title="PubMed">PMC</a>: <a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1721104">1721104</a>. <a href="/wiki/PubMed" title="PubMed">PMID</a>: <a href="https://www.ncbi.nlm.nih.gov/pubmed/10873172?dopt=Abstract" class="extiw" title="pmid:10873172">10873172</a>.</span></span> </li> <li id="cite_note-pmid12687430-22"><span class="mw-cite-backlink"><a href="#cite_ref-pmid12687430_22-0">↑</a></span> <span class="reference-text"><span class="citation" style="font-style:normal" id="CITEREFKotiwZhangDaggardReiss-Levy2003"><span style="font-variant: small-caps;">Kotiw</span>, M;&#32;<span style="font-variant: small-caps;">Zhang</span>, GW;&#32;<span style="font-variant: small-caps;">Daggard</span>, G;&#32;<span style="font-variant: small-caps;">Reiss-Levy</span>, E;&#32;<span style="font-variant: small-caps;">Tapsall</span>, JW;&#32;<span style="font-variant: small-caps;">Numa</span>, A&#32;«Late-onset and recurrent neonatal Group B streptococcal disease associated with breast-milk transmission».&#32;<i>Pediatric and developmental pathology&#160;: the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society</i>,&#32;6,&#32;3,&#32;2003,&#32;pàg.&#160;251–6. <a href="/wiki/DOI" title="DOI">DOI</a>: <a rel="nofollow" class="external text" href="https://dx.doi.org/10.1007%2Fs10024-001-0276-y">10.1007/s10024-001-0276-y</a>. <a href="/wiki/PubMed" title="PubMed">PMID</a>: <a href="https://www.ncbi.nlm.nih.gov/pubmed/12687430?dopt=Abstract" class="extiw" title="pmid:12687430">12687430</a>.</span></span> </li> <li id="cite_note-pmid16371885-23"><span class="mw-cite-backlink"><a href="#cite_ref-pmid16371885_23-0">↑</a></span> <span class="reference-text"><span class="citation" style="font-style:normal" id="CITEREFGastelumDasseyMascolaYasuda2005"><span style="font-variant: small-caps;">Gastelum</span>, DT;&#32;<span style="font-variant: small-caps;">Dassey</span>, D;&#32;<span style="font-variant: small-caps;">Mascola</span>, L;&#32;<span style="font-variant: small-caps;">Yasuda</span>, LM&#32;«Transmission of community-associated methicillin-resistant Staphylococcus aureus from breast milk in the neonatal intensive care unit».&#32;<i>The Pediatric Infectious Disease Journal</i>,&#32;24,&#32;12,&#32;2005,&#32;pàg.&#160;1122–4. <a href="/wiki/PubMed" title="PubMed">PMID</a>: <a href="https://www.ncbi.nlm.nih.gov/pubmed/16371885?dopt=Abstract" class="extiw" title="pmid:16371885">16371885</a>.</span></span> </li> <li id="cite_note-Mjagielski-24"><span class="mw-cite-backlink"><a href="#cite_ref-Mjagielski_24-0">↑</a></span> <span class="reference-text">. <span class="citation" style="font-style:normal" id="CITEREFJagielskiRastawickiKałużewskiGierczyński2007"><span style="font-variant: small-caps;">Jagielski</span>, Marek;&#32;<span style="font-variant: small-caps;">Rastawicki</span>, Waldemar;&#32;<span style="font-variant: small-caps;">Kałużewski</span>, Stanisław;&#32;<span style="font-variant: small-caps;">Gierczyński</span>, Rafał&#32;«<a rel="nofollow" class="external text" href="https://web.archive.org/web/20111003164323/http://www.pzh.gov.pl/oldpage/przeglad_epimed/56-1/561_07.pdf">Jersinioza – niedoceniana choroba zakaźna</a>»&#32;(en polish).&#32;<i>Przegl Epidemiol</i>,&#32;56,&#32;1,&#32;2007,&#32;pàg.&#160;57–64. Arxivat de l'<a rel="nofollow" class="external text" href="http://www.pzh.gov.pl/oldpage/przeglad_epimed/56-1/561_07.pdf">original</a> el 2011-10-03. <a href="/wiki/PubMed" title="PubMed">PMID</a>: <a href="https://www.ncbi.nlm.nih.gov/pubmed/12150068?dopt=Abstract" class="extiw" title="pmid:12150068">12150068</a>&#32;[Consulta: 20 abril 2012].</span> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20111003164323/http://www.pzh.gov.pl/oldpage/przeglad_epimed/56-1/561_07.pdf">Arxivat</a> 2011-10-03 a <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a>.</span> </li> <li id="cite_note-Pmielczarek-25"><span class="mw-cite-backlink"><a href="#cite_ref-Pmielczarek_25-0">↑</a></span> <span class="reference-text">. <span class="citation" style="font-style:normal" id="CITEREFMielczarek2004"><span style="font-variant: small-caps;">Mielczarek</span>, Paweł&#32;«<a rel="nofollow" class="external text" href="https://web.archive.org/web/20110919192407/http://www.chirurgia.opole.pl/pdf/gp_2004_1_69.pdf">Jersinioza – rzadko rozpoznawana choroba układu pokarmowego</a>»&#32;(en polish).&#32;<i>Prace poglądowe</i>,&#32;11,&#32;1,&#32;2004,&#32;pàg.&#160;69–74. Arxivat de l'<a rel="nofollow" class="external text" href="http://www.chirurgia.opole.pl/pdf/gp_2004_1_69.pdf">original</a> el 2011-09-19&#32;[Consulta: 20 abril 2012].</span></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="Enllaços_externs"><span id="Enlla.C3.A7os_externs"></span>Enllaços externs</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Trombocitop%C3%A8nia&amp;action=edit&amp;section=11" title="Modifica la secció: Enllaços externs"><span>modifica</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="http://www.thrombocytopenia.info/">Fòrum de Trombocitopènia </a></li> <li><a rel="nofollow" class="external text" href="http://www.dpd-deficiency.com/">Flourouracil/5-FU Toxicity &amp; DPD Deficiency Education - DPD-Deficiency.com</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20140517034842/http://dpd-deficiency.com/">Arxivat</a> 2014-05-17 a <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a>.</li></ul> <!-- NewPP limit report Parsed by mw‐web.eqiad.main‐6777b96b7d‐rdr7r Cached time: 20241203151010 Cache expiry: 2592000 Reduced expiry: false Complications: [show‐toc] CPU time usage: 0.301 seconds Real time usage: 0.505 seconds Preprocessor visited node count: 7637/1000000 Post‐expand include size: 68398/2097152 bytes Template argument size: 14566/2097152 bytes Highest expansion depth: 13/100 Expensive parser function count: 5/500 Unstrip recursion depth: 0/20 Unstrip post‐expand size: 30835/5000000 bytes Lua time usage: 0.107/10.000 seconds Lua memory usage: 3400315/52428800 bytes Number of Wikibase entities loaded: 1/400 --> <!-- Transclusion expansion time report (%,ms,calls,template) 100.00% 416.876 1 -total 61.28% 255.462 1 Plantilla:Infotaula_malaltia 34.36% 143.244 1 Plantilla:Referències 19.51% 81.320 20 Plantilla:Ref-publicació 4.66% 19.414 4 Plantilla:Ref-web 4.62% 19.270 25 Plantilla:If_both 2.77% 11.536 2 Plantilla:Ref-notícia 1.73% 7.192 2 Plantilla:Webarchive 1.70% 7.080 1 Plantilla:Ref-llibre 0.90% 3.753 2 Plantilla:Data_consulta --> <!-- Saved in parser cache with key cawiki:pcache:682981:|#|:idhash:canonical and timestamp 20241203151010 and revision id 34072923. 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