Research tool kit | Natural History Museum

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forms.</span></p> </div> </div> <div class="text parbase section"> <div data-gtm-component="text"> <p>Disclaimer: Content provided on this site contains the most recent version of the file at the time of Intervention Phase completion.聽</p> </div> </div> <div class="foundation5image parbase section"> <div> <figure class=" flow" role="group"> <picture> <source media="(max-width: 480px)" srcset="/content/dam/nhmwww/our-science/our-work/sustainability/DeWorm3_SOP_timeline-two-column.png.placeholder.480.480.png" data-srcset="/content/dam/nhmwww/our-science/our-work/sustainability/DeWorm3_SOP_timeline-two-column.png.thumb.480.480.png"/> <source media="(min-width: 481px) and (max-width: 768px)" srcset="/content/dam/nhmwww/our-science/our-work/sustainability/DeWorm3_SOP_timeline-two-column.png.placeholder.768.768.png" data-srcset="/content/dam/nhmwww/our-science/our-work/sustainability/DeWorm3_SOP_timeline-two-column.png.thumb.768.768.png"/> <source media="(min-width: 769px)" srcset="/content/dam/nhmwww/our-science/our-work/sustainability/DeWorm3_SOP_timeline-two-column.png.placeholder.1160.1160.png" data-srcset="/content/dam/nhmwww/our-science/our-work/sustainability/DeWorm3_SOP_timeline-two-column.png.thumb.1160.1160.png"/> <img class="lazy" src="/content/dam/nhmwww/our-science/our-work/sustainability/DeWorm3_SOP_timeline-two-column.png.placeholder.1160.1160.png" data-src="/content/dam/nhmwww/our-science/our-work/sustainability/DeWorm3_SOP_timeline-two-column.png.thumb.1160.1160.png" alt/> </picture> </figure> </div> </div> <div class="headertextimage parbase section"> <div data-gtm-component="hti" class="hti-wrapper " data-equalizer-watch > <div class="hti-box end columns hti-box__light-grey small-12 medium-12 large-12 " data-equalizer-watch > <div class="small-12 medium-12 large-12 columns hti-box--text-wrapper" > <h3> TRIAL PROTOCOLS </h3> <h3>DeWorm3 trial protocol</h3> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/publications/DW3_2018_Asbjornsdottir_TrialClusterProtocol_PLOSNTDs.pdf">Assessing the feasibility of interrupting the transmission of soil-transmitted helminths through mass drug administration: The DeWorm3 cluster randomized trial protocol</a></p> <p>PLoS Neglected Tropical Diseases 12(1), 2018</p> <h3>DeWorm3 implementation science protocol</h3> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/DW3_2018_Means_ImplementationScienceProtocol_PLOSNTDs.pdf">Evaluating the sustainability, scalability, and replicability of an STH transmission interruption intervention: The DeWorm3 implementation science protocol</a></p> <p>PLoS Neglected Tropical Diseases 12(1), 2018<br /> </p> </div> </div> </div> </div> <div class="headertextimage parbase section"> <div data-gtm-component="hti" class="hti-wrapper " data-equalizer-watch > <div class="hti-box end columns hti-box__light-grey small-12 medium-12 large-12 " data-equalizer-watch > <div class="small-12 medium-12 large-12 columns hti-box--text-wrapper" > <h3> SITE READINESS </h3> <p><b>Advisory boards are essential to the success of research trials as they help build and sustain overall support from communities affected by the study. How do you create and manage advisory boards?</b><br /> </p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_101.%20Community%20Advisory%20Board_072018.pdf">SOP 101 Community Advisory Board</a><br /> <a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_102.%20Implementation%20Science%20Advisory%20Board_072018.pdf">SOP 102 Implementation Science Advisory Board</a><br /> </p> <p><b>Stakeholder mapping is undertaken to identify individuals who influence or are affected by implementation of community-wide MDA for STH. How do you create a stakeholder map?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_103.%20Baseline%20stakeholder%20mapping_072018.pdf">SOP 103 Baseline Stakeholder mapping</a></p> <p><b>Pre-trial sensitisation encourages maximum support and engagement in the trial by stakeholders. How are sensitisation activities executed?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_104.%20Pre-trial%20sensitisation_072018.pdf">SOP 104 Pre-trial sensitisation</a></p> <p><i><a href="/content/dam/nhmwww/our-science/our-work/sustainability/DeWorm3_Emission%20radio%20Mono%20FM_2018.mp3">Benin radio announcement (French .mp3)</a><br /> <a href="/content/dam/nhmwww/our-science/our-work/sustainability/DeWorm3_Emission%20radio%20Mono%20FM_2018_English_translation.pdf">Benin radio announcement (English translation .pdf)</a></i></p> <p><i><a href="/content/dam/nhmwww/our-science/our-work/sustainability/DeWorm3_Fraternit%C3%A9%2013122017_French+English.pdf">Benin newspaper article (French and English translation .pdf) - Fraternit茅 13/12/2017</a><br /> <a href="/content/dam/nhmwww/our-science/our-work/sustainability/DeWorm3_La%20Nation%2013122017_French+English.pdf">Benin newspaper article (French and English translation .pdf) - La Nation 13/12/2017</a></i></p> <p><b>Study supplies should be available in good time and in good condition. How do we procure, order, store and keep an inventory to ensure efficient study supply use?</b><br /> </p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_105.%20Study%20supplies%20procurement,%20ordering,%20storage,%20and%20inventory_072018.pdf">SOP 105 Study supplies procurement, ordering, storage, and inventory</a></p> <p><b>Staff recruitment should be handled in a transparent, objective and equitable manner. How do we recruit staff to ensure the best applicants are chosen to meet the need of the trial?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_106.%20Recruitment%20procedures_072018.pdf">SOP 106 Recruitment procedures</a></p> </div> </div> </div> </div> <div class="headertextimage parbase section"> <div data-gtm-component="hti" class="hti-wrapper " data-equalizer-watch > <div class="hti-box end columns hti-box__light-grey small-12 medium-12 large-12 " data-equalizer-watch > <div class="small-12 medium-12 large-12 columns hti-box--text-wrapper" > <h3> CENSUS AND CLUSTER DEMARCATION </h3> <p>A baseline census is done so that at the end of the trial the results can be compared to see what has changed. The census also allows the households to be divided into clusters - the intervention arm and the control arm - based on baseline infection prevalence.聽</p> <p><b>Informed consent must be obtained from eligible participants before starting the trial. How do we ensure we have informed consent?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_201.%20Census%20informed%20consent%20v2%2020190121.pdf">SOP 201 Census informed consent</a><br /> <br /> <b>A baseline census is carried out to quantify the population size of the trial site and to establish a socio-demographic database to create a sampling frame and inform cluster demarcation. How is the census administered in the community?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_202.%20Administering%20the%20baseline%20census_072018.pdf">SOP 202 Administrating the baseline census</a><br /> <a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_203.%20Administering%20census%20updates%20v2.pdf">SOP 203 Administrating the census update</a></p> <p><b>All schools within the trial boundaries are surveyed to create a cluster school database and assess the presence and status of WASH facilities. How is a school facility survey administered?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_204.%20Administering%20the%20school%20facility%20survey%20v2%202018_10_04.pdf">SOP 204 Administrating the school facility survey</a></p> </div> </div> </div> </div> <div class="headertextimage parbase section"> <div data-gtm-component="hti" class="hti-wrapper " data-equalizer-watch > <div class="hti-box end columns hti-box__light-grey small-12 medium-12 large-12 " data-equalizer-watch > <div class="small-12 medium-12 large-12 columns hti-box--text-wrapper" > <h3> LONGITUDINAL MONITORING SURVEY </h3> <p><b>As with the baseline census, informed consent must be received from eligible participants. Data from stool samples collected at time points in the longitudinal cohorts will assess rates of change in STH prevalence, quantify reinfection and validate the models. How is the baseline longitudinal monitoring survey administered?</b><br /> </p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_303.%20Administering%20the%20baseline%20longitudinal%20monitoring%20survey%20v2.pdf">SOP 303 Administering the first longitudinal monitoring survey (incl eligibility and consent)</a></p> <p><b>What are the procedures for treating individuals in control clusters identified as positive cases (children with any intensity STH infection and adults with moderate to high intensity STH infection)?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/Deworm3_SOP_304.%20Follow%20up%20procedures%20for%20positive%20cases%20v3.pdf">SOP 304 Follow-up procedures with positive cases聽</a></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_305.%20Administering%20the%20follow%20up%20longitudinal%20monitoring%20survey%20V2.pdf">SOP 305聽Administering follow-up longitudinal monitoring surveys</a></p> </div> </div> </div> </div> <div class="headertextimage parbase section"> <div data-gtm-component="hti" class="hti-wrapper " data-equalizer-watch > <div class="hti-box end columns hti-box__light-grey small-12 medium-12 large-12 " data-equalizer-watch > <div class="small-12 medium-12 large-12 columns hti-box--text-wrapper" > <h3> MODELLING </h3> <p>An all-in-one聽<b>python聽</b>class for the stochastic modelling of transmission and treatment of<b>聽Soil-Transmitted Helminthiasis (STH)聽</b>developed by Imperial College London can be found <a href="https://sites.google.com/view/helmpy">here</a>.</p> </div> </div> </div> </div> <div class="headertextimage parbase section"> <div data-gtm-component="hti" class="hti-wrapper " data-equalizer-watch > <div class="hti-box end columns hti-box__light-grey small-12 medium-12 large-12 " data-equalizer-watch > <div class="small-12 medium-12 large-12 columns hti-box--text-wrapper" > <h3> CROSS-SECTIONAL MONITORING SURVEY </h3> <p><b>At three points during the study period, a cross-sectional survey of randomly selected participants is undertaken with new selection taking place each time. How are the cross-sectional surveys administered?</b><br /> </p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_403.%20Administering%20the%20baseline%20cross%20sectional%20survey_072018.pdf">SOP 403 Administering the baseline cross-sectional survey</a><br /> <br /> </p> </div> </div> </div> </div> <div class="headertextimage parbase section"> <div data-gtm-component="hti" class="hti-wrapper " data-equalizer-watch > <div class="hti-box end columns hti-box__light-grey small-12 medium-12 large-12 " data-equalizer-watch > <div class="small-12 medium-12 large-12 columns hti-box--text-wrapper" > <h3> MDA DELIVERY AND COVERAGE SURVEY </h3> <p><b>How do we ensure participation from the community?</b><br /> </p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/503_DeWorm3_IEC_and_Sensitization_Guidelines_2017_04_18%20(1).pdf">SOP 503 Sensitisation and IEC for community-based deworming</a></p> <p><b>Who is eligible for treatment?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_506.%20Pre%20MDA%20screening%20for%20treatment%20eligibility%20V1.pdf">SOP 506 Pre-MDA screening for treatment eligibility during community-wide treatment</a></p> <p><b>How is albendazole distributed in communities?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/Deworm3_SOP_507.%20Conducting%20community-wide%20mass%20drug%20administration%20(MDA)%20V1.pdf">SOP 507聽Administration of albendazole in communities</a></p> <p><b>How is albendazole distributed in schools?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_508.%20Administration%20of%20albendazole%20in%20schools%20V1.pdf">SOP 508 Administration of albendazole in schools</a></p> <p><b>How is the treatment data captured digitally?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_509.%20Completion%20of%20the%20SurveyCTO%20MDA%20Treatment%20log%20V2.pdf">SOP 509聽Completion of the SurveyCTO MDA treatment log</a></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_510.%20Completion%20of%20the%20SurveyCTO%20MDA%20Treatment%20log%20(MDA2-6)%20V2.pdf">SOP 510 Completion of the SurveyCTO MDA2 treatment log</a></p> <p><b>What happens when there is an adverse event?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_511.%20Surveillance%20&%20reporting%20of%20AE-SAEs%20V1.pdf">SOP 511 Surveillance/reporting of adverse events and serious adverse events</a></p> <p><b>Once the MDA is completed, a survey must be taken to ensure high participation rates. How is the coverage survey administrated?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_512.%20Administration%20of%20coverage%20%20surveys%20V2.pdf">SOP 512聽Administration of coverage surveys</a><i><br /> </i></p> </div> </div> </div> </div> <div class="headertextimage parbase section"> <div data-gtm-component="hti" class="hti-wrapper " data-equalizer-watch > <div class="hti-box end columns hti-box__light-grey small-12 medium-12 large-12 " data-equalizer-watch > <div class="small-12 medium-12 large-12 columns hti-box--text-wrapper" > <h3> LAB WORK </h3> <p><b>How are sample aliquots prepared?</b><br /> </p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_706.%20Stool%20sample%20reception,%20aliquoting%20and%20storage%20V2.pdf">SOP 706 Stool sample reception, aliquoting and storage</a></p> <p><b>How are samples prepared for Kato Katz?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_707.%20Kato-Katz%20preparation%20and%20analysis%20V1.pdf">SOP 707聽Kato Katz preparation and analysis (prevalence, intensity, and fertilized eggs)</a></p> <p>聽</p> </div> </div> </div> </div> <div class="headertextimage parbase section"> <div data-gtm-component="hti" class="hti-wrapper " data-equalizer-watch > <div class="hti-box end columns hti-box__light-grey small-12 medium-12 large-12 " data-equalizer-watch > <div class="small-12 medium-12 large-12 columns hti-box--text-wrapper" > <h3> IMPLEMENTATION SCIENCE </h3> <p>Implementation Science is run co-currently with the trial protocol. The study involves working in-country to identify barriers to research uptake.聽</p> <p><b>Systematic participant selection is vital to attain and evaluate a representative set of perspectives, experiences, and opinions. How do we select participants?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_801.%20Participant%20selection%20for%20individual%20interviews_2017_08_24.pdf">SOP 801 Participant selection for 聽individual interviews</a><br /> <a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_802.%20Participant%20selection%20for%20focus%20group%20discussions_2017_08_24.pdf">SOP 802 Participant selection for focus group discussions</a><br /> <a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_807.%20Participant%20selection%20for%20structural%20readiness%20survey_2017_10_12.pdf">SOP 807 聽Participant selection for structural readiness survey</a></p> <p><b>Informed consent must be obtained from eligible participants before starting the trial. How do we ensure we have informed consent?</b><br /> </p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_803.%20Individual%20interviews%20informed%20consent_2017_08_24.pdf">SOP 803 Individual interviews informed consent</a><br /> <a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_804.%20Focus%20group%20discussions%20informed%20consent_2017_08_24%20MALAWI.pdf">SOP 804 Focus group discussions informed consent</a></p> <p><b>Focus groups and individual interviews are used to collect descriptive data regarding a specific topic. How do we ensure we collect data using the same procedures across all interviews and groups?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_805.%20Conducting%20focus%20group%20discussions_2017_08_24.pdf">SOP 805 Conducting focus group discussions</a><br /> <a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_806.%20Conducting%20individual%20interviews_2017_08_24.pdf">SOP 806 Conducting individual interviews</a></p> <p><b>Structural readiness drives the psychological readiness of different stakeholders in the health system to implement community-wide MDA. How to we survey the 'readiness' of stakeholders?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_808.%20Conducting%20structural%20readiness%20surveys_2017_08_24.pdf">SOP 808 Conducting structural readiness surveys</a></p> <p><b>In order to better understand the way in which MDA is delivered in each cluster, process mapping takes place in all clusters following each round of MDA. In-depth process mapping is undertaken in six of these clusters. How do we choose the six clusters in which do conduct in-depth process mapping?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_809.%20Cluster%20selection%20for%20indepth%20process%20mapping_2017_08_24.pdf">SOP 809 Cluster selection for indepth process mapping</a><br /> <br /> <b>Once the clusters are chosen for in-depth process mapping, activities are carried out in conjunction with relevant Ministries. How do we conduct in-depth process mapping?</b><br /> </p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_810.%20Conducting%20indepth%20process%20mapping_2017_08_24.pdf">SOP 810 Conducting indepth process mapping</a></p> <p><b>How are routine workflow tracking worksheets completed in each cluster?</b><br /> </p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_811.%20Conducting%20routine%20workflow%20tracking%20worksheets_2017_08_24.pdf">SOP 811 Conducting routine workflow tracking worksheets</a></p> <p><b>How do we collect and compile financial cost data?</b><br /> </p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_812.%20Cost%20collection%20SOP_2017_10_06.pdf">SOP 812 Cost collection</a></p> <p><b>How do we collect data about project workers?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_813.%20Collecting%20demographic%20information%20from%20project%20workers%2020180222.pdf">SOP 813聽Collecting demographic information from project workers</a></p> <p><b>How do we complete a stakeholder mapping exercise?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_814.%20Endline%20stakeholder%20mapping_FINAL_20200921.pdf">SOP 814 Endline Stakeholder Mapping</a></p> <p><b>How do we select participants for midline and endline qualitative research?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_815.%20Participant%20selection%20for%20midline%20and%20endline%20qualitative%20research.pdf">SOP 815 Participant selection for midline and endline qualitative research</a></p> <p>聽</p> </div> </div> </div> </div> <div class="headertextimage parbase section"> <div data-gtm-component="hti" class="hti-wrapper " data-equalizer-watch > <div class="hti-box end columns hti-box__light-grey small-12 medium-12 large-12 " data-equalizer-watch > <div class="small-12 medium-12 large-12 columns hti-box--text-wrapper" > <h3> DATA MANAGEMENT </h3> <p><b>How do data managers initialize data collection devices and provide settings for the mobile devices and data collection application, SurveyCTO Collect?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_901.%20Set%20up%20mobile%20data%20collection%20devices%20V3.pdf#">SOP 901 SurveyCTO installation and Set Up on Smartphones</a></p> <p><b>How do data managers print household ID stickers for the baseline census, individual sampling and census updates?</b><br /> </p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_902.%20Printing%20Household%20ID%20Barcodes_072018.pdf">SOP 902 Printing of household ID barcodes</a></p> <p><b>Site registries are required for the population of the SurveyCTO surveys. These registries include the Field Officer Registry, Village Registry, and School Registry. How are the registries loaded into the SurveyCTO forms?</b></p> <p><a href="/content/dam/nhmwww/our-science/our-work/sustainability/deworm3/DeWorm3_SOP_903.%20Creating%20site%20registries%20for%20populating%20SurveyCTO%20surveys_072018.pdf">SOP 903 Creating site registries for populating SurveyCTO surveys</a></p> <p><b>Census and survey data are used to visualise households during activities using the software QGIS. 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