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Sterile Fill Finish - Parenteral Drug Development & Manufacturing - Patheon pharma services

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With many format and formulation choices available including lyophilized, we can manufacture the right format for every stage of the product lifecycle.</p> <p>Flexible sterile fill-finish services at our cGMP facilities can accommodate a variety of molecules including <a href="https://www.patheon.com/us/en/our-capabilities/large-molecule/biologics.html">biologics</a> and <a href="https://www.patheon.com/us/en/our-capabilities/advanced-therapies/mrna-development-and-manufacturing-services.html">mRNA</a>. For preclinical work, non-cGMP options are also available. 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} </style> </div> <div class="text aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn aem-GridColumn--default--12"> <div id="text-a7cc305cdb" class="cmp-text list-style-bullets"> <h2><b>Vial, prefilled syringe, and cartridge fill-finish offerings</b></h2> </div> </div> <div class="text aem-GridColumn aem-GridColumn--default--12"> <div id="text-c42844d12d" class="cmp-text list-style-bullets"> <p>We offer a broad range of sterile parenteral dosage formats to meet your molecule’s specific needs as you move through preclinical to first-in-human (FIH) studies and beyond.</p> </div> </div> <div class="cmp-container aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--hide aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--default--12 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner img-fluid " id="container-1355209042"> <div class="aem-Grid aem-Grid--12 "> <div class="image aem-GridColumn--xsmall--12 aem-GridColumn aem-GridColumn--default--12"> <div data-cmp-is="image" data-cmp-lazythreshold="0" data-cmp-src="/content/patheon/us/en/our-capabilities/steriles/_jcr_content/root/responsivegrid/well_copy_copy_copy/container_1676354999/image.coreimg{.width}.png/1719498074368/steriles-img.png" data-asset="/content/dam/patheon/global/site-images/steriles/steriles-img.png" data-asset-id="38ac5736-7a71-4d19-a107-90402c2dd3a3" data-title="steriles" id="image-ef4a44e680" class="cmp-image false " itemscope itemtype="http://schema.org/ImageObject"> <img src="/content/patheon/us/en/our-capabilities/steriles/_jcr_content/root/responsivegrid/well_copy_copy_copy/container_1676354999/image.coreimg.png/1719498074368/steriles-img.png" class="cmp-image__image false " itemprop="contentUrl" data-cmp-hook-image="image" alt="steriles"/> </div> </div> </div> </div> <style type="text/css"> #container-1355209042{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1355209042 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn aem-GridColumn--default--12 aem-GridColumn--xsmall--hide"> <div class="cmp-container-inner " id="container-1112305565"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="cmp-container aem-GridColumn--xsmall--12 aem-GridColumn aem-GridColumn--default--12"> <div class="cmp-container-inner " id="container-148010133"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="text aem-GridColumn--default--none aem-GridColumn aem-GridColumn--default--10 aem-GridColumn--offset--default--1"> <div id="text-f96d7261f3" class="cmp-text list-style-bullets"> <div class="table-responsive"><center> </center> <table cellspacing="0" border="1" width="100%"> <tbody><tr><td width="20%" style="padding: 1.0%;border: solid thin;"> </td> <td width="10%" style="padding: 1.0%;border: solid thin;"><center><img src="/content/dam/patheon/global/site-images/steriles/liquid-filled-vials.png" alt="Liquid-filled vials"/></center> </td> <td width="10%" style="padding: 1.0%;border: solid thin;"><center><img src="/content/dam/patheon/global/site-images/steriles/lyophilized-vials.png" alt="Lyophilized vials"/></center> </td> <td width="10%" style="padding: 1.0%;border: solid thin;"><center><img src="/content/dam/patheon/global/site-images/steriles/prefilled-syringe.png" alt="Prefilled syringe"/></center> </td> <td width="10%" style="padding: 1.0%;border: solid thin;"><center><img src="/content/dam/patheon/global/site-images/steriles/prefilled-cartridges.png" alt="Prefilled cartridges"/></center> </td> </tr><tr><td style="padding: 1.0%;border: solid thin;"> </td> <td style="padding: 1.0%;border: solid thin;"><center><b>Liquid-filled vials</b></center> <b></b></td> <td style="padding: 1.0%;border: solid thin;"><b><center>Lyophilized vials</center> </b></td> <td style="padding: 1.0%;border: solid thin;"><b><center>Prefilled syringes</center> </b></td> <td style="padding: 1.0%;border: solid thin;"><b><center>Prefilled cartridges</center> </b></td> </tr><tr><td style="padding: 1.0%;border: solid thin;"><b>Key services</b></td> <td colspan="2" style="padding: 1.0%;border: solid thin;"><center>Vial labeling and packaging</center> </td> <td style="padding: 1.0%;border: solid thin;"><center> </center> </td> <td style="padding: 1.0%;border: solid thin;"><center>Auto injector pen assembly and packaging</center> </td> </tr><tr><td style="padding: 1.0%;border: solid thin;"><b>Commercial format ranges</b></td> <td style="padding: 1.0%;border: solid thin;"><center>2-500 mL</center> </td> <td style="padding: 1.0%;border: solid thin;"><center>2-100 mL</center> </td> <td style="padding: 1.0%;border: solid thin;"><center>0.5-20 mL</center> </td> <td style="padding: 1.0%;border: solid thin;"><center>0.5-20 mL</center> </td> </tr><tr><td style="padding: 1.0%;border: solid thin;"><b>Development format ranges</b></td> <td style="padding: 1.0%;border: solid thin;"><center>2-100 mL</center> </td> <td style="padding: 1.0%;border: solid thin;"><center>2-100 mL</center> </td> <td style="padding: 1.0%;border: solid thin;"><center>0.5-20 mL</center> </td> <td style="padding: 1.0%;border: solid thin;"><center>0.5-20 mL</center> </td> </tr></tbody></table> </div> </div> </div> <div class="text aem-GridColumn--default--none aem-GridColumn aem-GridColumn--default--11 aem-GridColumn--offset--default--1"> <div id="text-ecc0af284d" class="cmp-text list-style-bullets"> <p> </p> <p><a href="https://www.patheon.com/us/en/site-locations.html">Manufacturing sites are global</a> including US and EU. Contact your representative for site-specific information.</p> </div> </div> </div> </div> <style type="text/css"> #container-148010133{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-148010133 { border-radius: px; } </style> </div> </div> </div> <style type="text/css"> #container-1112305565{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1112305565 { border-radius: px; } </style> </div> <div class="cmp-well aem-GridColumn aem-GridColumn--default--12"> <div class="well " style="background-position-x: center;background-position-y: center;" id="well-1966202309"> <div class="container-fluid container-lg "> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> </div> </div> </div> <style type="text/css"> #well-1966202309 { border-radius: 0px; } </style> </div> <div class="text aem-GridColumn aem-GridColumn--default--12"> <div id="text-de4687dba8" class="cmp-text list-style-bullets"> <h2>Aseptic fill-finish solutions for parenteral drug products</h2> </div> </div> <div class="text aem-GridColumn aem-GridColumn--default--12"> <div id="text-10075f4ecd" class="cmp-text list-style-bullets"> <p>Work with a leading CDMO of parenteral/injectables to take your medicine from formulation through commercialization. Our teams can help at every phase of the product lifecycle, leveraging decades of experience to help you produce different parenteral drug formulations as your needs evolve.</p> </div> </div> <div class="cmp-container aem-GridColumn aem-GridColumn--default--12"> <div class="cmp-container-inner py-3 " id="container-930855119"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="cmp-accordion aem-GridColumn aem-GridColumn--default--12"> <div class="accordion" id="sterile-formulation-development"> <div class="accordion-item"> <div class="accordion-header" id="heading-sterile-formulation-development"> <button class="accordion-button collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#collapse-sterile-formulation-development" aria-expanded="true" aria-controls="collapse-sterile-formulation-development"> <span> <span class="accordion-title">Formulation development</span><br/> <span class="accordion-subtitle">Avoid rework and costly delays by getting parenteral formulations right from the start</span> </span> </button> </div> <div id="collapse-sterile-formulation-development" class="accordion-collapse collapse " aria-labelledby="heading-sterile-formulation-development" data-bs-parent="#sterile-formulation-development"> <div class="accordion-body"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 aem-Grid--xsmall--12 aem-Grid--medium--12 "> <div class="cmp-container aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner " id="container-295886803"> <div class="aem-Grid aem-Grid--6 aem-Grid--default--6 aem-Grid--xsmall--6 aem-Grid--medium--12 "> <div class="text aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--xsmall--6 aem-GridColumn--default--6"> <div id="text-86ad657cc1" class="cmp-text list-style-check"> <p>Developing the correct formulation can be time-consuming when you can least afford delays. The chemical nature of the compound may present significant challenges like temperature and shear sensitivity, poor solubility, and high potency. Lyophilization, if desired, requires cycle optimization.</p> <p>Our established parenteral formulation processes include:</p> <p>1. <b>Pre-formulation:</b> Optimal pH, ionic strength, degradation pathways, and stability studies<br /> 2. <b>Formulation development: </b>Select and define optimal levels for all excipients using OFaT and/or design of experiments (DoE) approaches<br /> 3. <b>Formulation confirmation: </b>Confirm stability of the selected final formulation using analytical tools</p> <p>Learn more about our formulation services for:</p> <p><a href="https://www.patheon.com/us/en/our-capabilities/small-molecule/api-development.html">Small molecule API</a></p> <p><a href="https://www.patheon.com/us/en/our-capabilities/large-molecule/biologics.html">Biologics: Protein antibodies</a></p> <p><a href="https://www.patheon.com/us/en/our-capabilities/advanced-therapies.html">mRNA vaccines and therapies</a></p> </div> </div> </div> </div> <style type="text/css"> #container-295886803{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-295886803 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--offset--medium--0 aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--medium--newline aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner ms-lg-3 ms-md-0 " id="container-1025522986"> <div class="aem-Grid aem-Grid--6 aem-Grid--default--6 aem-Grid--xsmall--6 aem-Grid--medium--6 "> <div class="image aem-GridColumn aem-GridColumn--xsmall--6 aem-GridColumn--default--6 aem-GridColumn--medium--6"> <div data-cmp-is="image" data-cmp-lazythreshold="0" data-cmp-src="/content/patheon/us/en/our-capabilities/steriles/_jcr_content/root/responsivegrid/well_copy_copy_copy/container_977021561/accordion/accordionparsys/container_copy_604185778/image.coreimg{.width}.png/1716985970237/vials.png" data-asset="/content/dam/patheon/global/site-images/steriles/Vials.png" data-asset-id="0b31c5f5-a02e-4b04-8394-fe204f22666d" data-title="Parenteral dosage format: vials" id="image-52b1e5f6f9" class="cmp-image false " itemscope itemtype="http://schema.org/ImageObject"> <img src="/content/patheon/us/en/our-capabilities/steriles/_jcr_content/root/responsivegrid/well_copy_copy_copy/container_977021561/accordion/accordionparsys/container_copy_604185778/image.coreimg.png/1716985970237/vials.png" class="cmp-image__image false " itemprop="contentUrl" data-cmp-hook-image="image" alt="Parenteral dosage format: vials"/> </div> </div> </div> </div> <style type="text/css"> #container-1025522986{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1025522986 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--default--newline aem-GridColumn--default--12 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner " id="container-427141617"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 aem-Grid--xsmall--12 "> <div class="text aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--default--12"> <div id="text-1ca5ade143" class="cmp-text list-style-check"> <h4><b>Reduce costs and assure quality during preclinical and phase I studies</b></h4> <p>Preclinical and phase I studies can have lengthy timelines that lead to increased costs. Ensuring quality and consistency across processes in early development is critical as you move from phase to phase. Lyophilization, use of non-cGMP batches, and pre-qualified components can address both concerns. Lyophilization increases stability, leading to a longer shelf-life for the duration of clinical trials.</p> <p>To save time and money, we offer non-cGMP suites that ensure scalable equipment. The setup of our non-cGMP lines mimics our cGMP lines — it’s the same material without the aseptic processing and costs associated with cGMP spaces.</p> </div> </div> </div> </div> <style type="text/css"> #container-427141617{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-427141617 { border-radius: px; } </style> </div> </div> </div> </div> </div> </div> </div> </div> </div> <style type="text/css"> #container-930855119{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-930855119 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn aem-GridColumn--default--12"> <div class="cmp-container-inner py-3 " id="container-2077447798"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="cmp-container aem-GridColumn aem-GridColumn--default--12"> <div class="cmp-container-inner " id="container-970517536"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 "> <div class="cmp-accordion aem-GridColumn aem-GridColumn--default--12"> <div class="accordion" id="sterile-manufacturing"> <div class="accordion-item"> <div class="accordion-header" id="heading-sterile-manufacturing"> <button class="accordion-button collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#collapse-sterile-manufacturing" aria-expanded="true" aria-controls="collapse-sterile-manufacturing"> <span> <span class="accordion-title">Clinical and commercial manufacture</span><br/> <span class="accordion-subtitle">Successfully transfer and scale your product to meet global demand</span> </span> </button> </div> <div id="collapse-sterile-manufacturing" class="accordion-collapse collapse " aria-labelledby="heading-sterile-manufacturing" data-bs-parent="#sterile-manufacturing"> <div class="accordion-body"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 aem-Grid--medium--12 "> <div class="cmp-container aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--default--6 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner ms-lg-3 ms-md-0 " id="container-1568249205"> <div class="aem-Grid aem-Grid--6 aem-Grid--small--6 aem-Grid--default--6 aem-Grid--xsmall--6 aem-Grid--medium--12 "> <div class="text aem-GridColumn--small--none aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--offset--default--0 aem-GridColumn--offset--medium--0 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--offset--small--0 aem-GridColumn--default--6"> <div id="text-8137989647" class="cmp-text list-style-bullets"> <p>Improve your chances of approval. Patheon pharma services can help you balance speed, regulatory needs, and the supply chain as you scale up. We offer the ability to:</p> </div> </div> <div class="cmp-container aem-GridColumn--offset--medium--0 aem-GridColumn--default--none aem-GridColumn--medium--newline aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner p-3 " id="container-1827095363"> <div class="aem-Grid aem-Grid--6 aem-Grid--small--6 aem-Grid--default--6 aem-Grid--xsmall--6 aem-Grid--medium--6 "> <div class="text aem-GridColumn--small--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--offset--small--0 aem-GridColumn--default--6 aem-GridColumn--offset--default--0 aem-GridColumn--medium--6"> <div id="text-59d476ac7b" class="cmp-text list-style-check"> <ul style="color: rgb(38,34,98);"> <li style="color: rgb(38,34,98);"><b>Navigate a complex regulatory environment at a global scale </b></li> <li style="color: rgb(38,34,98);"><b>Get your product to market and patients quicker</b></li> <li style="color: rgb(38,34,98);"><b>Execute tech transfers with speed and efficiency</b></li> <li style="color: rgb(38,34,98);"><b>Ensure a robust supply chain within a global network</b></li> </ul> </div> </div> </div> </div> <style type="text/css"> #container-1827095363{ background-image: url(''); background-color: #F7F7F7; background-size: cover; background-position: center; min-height: px; } #container-1827095363 { border-radius: px; } </style> </div> <div class="text aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6"> <div id="text-3f6637660e" class="cmp-text list-style-bullets"> <p>Our experienced regulatory teams have an enviable track record of drug commercialization success for our clients. Leverage our commercial production and <a href="https://www.patheon.com/us/en/our-capabilities/clinical-trial-services.html">clinical trial solutions</a> to gain extensive access to global technical experts, capability, regulatory insights, and transportation.</p> <p>Learn more about our <a href="https://www.patheon.com/us/en/our-capabilities/commercial-services.html">pharma commercialization services</a>.</p> </div> </div> </div> </div> <style type="text/css"> #container-1568249205{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1568249205 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--offset--medium--0 aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--medium--newline aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--default--6 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner ms-lg-3 ms-md-0 " id="container-228803821"> <div class="aem-Grid aem-Grid--6 aem-Grid--default--6 aem-Grid--xsmall--6 aem-Grid--medium--6 "> <div class="image aem-GridColumn aem-GridColumn--xsmall--6 aem-GridColumn--default--6 aem-GridColumn--medium--6"> <div data-cmp-is="image" data-cmp-lazythreshold="0" data-cmp-src="/content/patheon/us/en/our-capabilities/steriles/_jcr_content/root/responsivegrid/well_copy_copy_copy/container/container_1217410821/accordion_741899978/accordionparsys/container_copy_60418/image.coreimg{.width}.jpeg/1718652119252/sterile-fill-finish.jpeg" data-asset="/content/dam/patheon/global/site-images/steriles/sterile-fill-finish.jpg" data-asset-id="50fd541d-43d2-44dc-bb1f-82d0fec86684" data-title="Sterile fill and finish process" id="image-f38a3de349" class="cmp-image false " itemscope itemtype="http://schema.org/ImageObject"> <img src="/content/patheon/us/en/our-capabilities/steriles/_jcr_content/root/responsivegrid/well_copy_copy_copy/container/container_1217410821/accordion_741899978/accordionparsys/container_copy_60418/image.coreimg.jpeg/1718652119252/sterile-fill-finish.jpeg" class="cmp-image__image false " itemprop="contentUrl" data-cmp-hook-image="image" alt="Sterile fill and finish process"/> </div> </div> </div> </div> <style type="text/css"> #container-228803821{ background-image: url(''); 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background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1116705402 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--default--6 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner ms-lg-3 ms-md-0 " id="container-696591194"> <div class="aem-Grid aem-Grid--6 aem-Grid--small--6 aem-Grid--default--6 aem-Grid--xsmall--6 aem-Grid--medium--12 "> <div class="text aem-GridColumn--small--none aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--offset--default--0 aem-GridColumn--offset--medium--0 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--offset--small--0 aem-GridColumn--default--6"> <div id="text-3128568bfc" class="cmp-text list-style-bullets"> <p>Whether you have a dosage format in mind or are exploring your options, we offer a variety of packaging choices. In one year, we produced more than 130 million sterile liquid and lyophilized vials and manufactured 40 dosage forms. As a result, we have many pre-qualified components and standardized processes.</p> <p>We offer:</p> </div> </div> <div class="cmp-container aem-GridColumn--offset--medium--0 aem-GridColumn--default--none aem-GridColumn--medium--newline aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--6 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner p-3 " id="container-1174536500"> <div class="aem-Grid aem-Grid--6 aem-Grid--small--6 aem-Grid--default--6 aem-Grid--xsmall--6 aem-Grid--medium--6 "> <div class="text aem-GridColumn--small--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--offset--small--0 aem-GridColumn--default--6 aem-GridColumn--offset--default--0 aem-GridColumn--medium--6"> <div id="text-692664dd70" class="cmp-text list-style-check"> <ul style="color: rgb(38,34,98);"> <li style="color: rgb(38,34,98);"><b>Small- and large-volume parenterals</b></li> <li style="color: rgb(38,34,98);"><b>Liquid-filled vials</b></li> <li style="color: rgb(38,34,98);"><b>Lyophilized vials</b></li> <li style="color: rgb(38,34,98);"><b>Extensive range of vial sizes including ISO standard</b></li> <li style="color: rgb(38,34,98);"><b>Pre-filled syringes and cartridges</b></li> </ul> </div> </div> </div> </div> <style type="text/css"> #container-1174536500{ background-image: url(''); 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It features a unique co-location of mRNA manufacturing capabilities with LNP and fill-finish services to help streamline your processes and mitigate risks.</p> </div> </div> </div> </div> <style type="text/css"> #container-475042206{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-475042206 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--small--none aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--offset--phone--0 aem-GridColumn--offset--default--0 aem-GridColumn--offset--medium--2 aem-GridColumn--small--8 aem-GridColumn--phone--none aem-GridColumn--xsmall--none aem-GridColumn--phone--10 aem-GridColumn aem-GridColumn--offset--small--2 aem-GridColumn--default--6 aem-GridColumn--medium--8"> <div class="cmp-container-inner ms-lg-3 ms-md-0 " id="container-1472795711"> <div class="aem-Grid aem-Grid--6 aem-Grid--small--8 aem-Grid--default--6 aem-Grid--xsmall--12 aem-Grid--phone--10 aem-Grid--medium--8 "> </div> </div> <style type="text/css"> #container-1472795711{ background-image: url('/content/dam/patheon/global/library/thumbnails/site-locations/site-monza-italy-2.png'); background-color: ; background-size: cover; background-position: center; min-height: 338px; } #container-1472795711 { border-radius: 6px; } </style> </div> </div> </div> <style type="text/css"> #container-1881688916{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1881688916 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn aem-GridColumn--default--12"> <div class="cmp-container-inner " id="container-630745341"> <div class="aem-Grid aem-Grid--12 aem-Grid--small--12 aem-Grid--default--12 aem-Grid--xsmall--12 aem-Grid--medium--12 "> <div class="cmp-container aem-GridColumn--small--none aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--newline aem-GridColumn--offset--default--0 aem-GridColumn--offset--medium--0 aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--offset--small--0 aem-GridColumn--default--6"> <div class="cmp-container-inner py-5 " id="container-1813828783"> <div class="aem-Grid aem-Grid--6 aem-Grid--small--12 aem-Grid--default--6 aem-Grid--xsmall--6 aem-Grid--medium--12 "> <div class="text aem-GridColumn--small--none aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--offset--default--0 aem-GridColumn--offset--medium--0 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--xsmall--6 aem-GridColumn--small--12 aem-GridColumn--offset--small--0 aem-GridColumn--default--5"> <div id="text-7ec83fa5e7" class="cmp-text list-style-bullets"> <h4><b><a href="https://www.patheon.com/us/en/site-locations/greenville-nc.html">Greenville, North Carolina, USA</a></b></h4> </div> </div> <div class="text aem-GridColumn--small--none aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--offset--default--0 aem-GridColumn--offset--medium--0 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--xsmall--6 aem-GridColumn--small--12 aem-GridColumn--offset--small--0 aem-GridColumn--default--6"> <div id="text-2a8cec4b36" class="cmp-text list-style-bullets"> <p>Our Greenville, NC facility is a large, multipurpose pharmaceutical manufacturing and packaging campus. This site provides both solid dose form manufacturing and packaging and sterile dose manufacturing, filling, and lyophilization of both biopharmaceuticals and small molecules.</p> </div> </div> </div> </div> <style type="text/css"> #container-1813828783{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1813828783 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--small--none aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--offset--default--0 aem-GridColumn--offset--medium--2 aem-GridColumn--small--8 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--offset--small--2 aem-GridColumn--default--6 aem-GridColumn--medium--8"> <div class="cmp-container-inner ms-lg-3 ms-md-0 " id="container-797565001"> <div class="aem-Grid aem-Grid--6 aem-Grid--small--8 aem-Grid--default--6 aem-Grid--xsmall--6 aem-Grid--medium--8 "> </div> </div> <style type="text/css"> #container-797565001{ background-image: url('/content/dam/patheon/global/library/thumbnails/site-locations/site-nc-greenville.jpg'); background-color: ; background-size: cover; background-position: center; min-height: 338px; } #container-797565001 { border-radius: 6px; } </style> </div> </div> </div> <style type="text/css"> #container-630745341{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-630745341 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn aem-GridColumn--default--12"> <div class="cmp-container-inner " id="container-920287546"> <div class="aem-Grid aem-Grid--12 aem-Grid--small--12 aem-Grid--default--12 aem-Grid--xsmall--12 aem-Grid--medium--12 "> <div class="cmp-container aem-GridColumn--small--none aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--offset--default--0 aem-GridColumn--offset--medium--0 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--offset--small--0 aem-GridColumn--default--6"> <div class="cmp-container-inner py-5 " id="container-1824912584"> <div class="aem-Grid aem-Grid--6 aem-Grid--small--12 aem-Grid--default--6 aem-Grid--xsmall--12 aem-Grid--medium--12 "> <div class="text aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--default--5 aem-GridColumn--small--5 aem-GridColumn--offset--default--0"> <div id="text-0ad13d7e7c" class="cmp-text list-style-bullets"> <h4><b><a href="https://www.patheon.com/us/en/site-locations/ferentino-it.html">Ferentino, Italy</a></b></h4> </div> </div> <div class="text aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--small--12 aem-GridColumn--default--6"> <div id="text-b0cc0d815f" class="cmp-text list-style-bullets"> <p>Our Ferentino facility is 14,034 sq. m. (151,061 sq. ft.), specializing in integrated sterile liquid and lyophilized product development and commercial manufacturing, including high-potency products and LVP.</p> </div> </div> </div> </div> <style type="text/css"> #container-1824912584{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1824912584 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--small--none aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--offset--default--0 aem-GridColumn--offset--medium--2 aem-GridColumn--small--8 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--offset--small--2 aem-GridColumn--default--6 aem-GridColumn--medium--8"> <div class="cmp-container-inner ms-lg-3 ms-md-0 " id="container-1991616823"> <div class="aem-Grid aem-Grid--6 aem-Grid--small--8 aem-Grid--default--6 aem-Grid--xsmall--12 aem-Grid--medium--8 "> </div> </div> <style type="text/css"> #container-1991616823{ background-image: url('/content/dam/patheon/global/library/thumbnails/site-locations/site-it-ferentino.jpg'); background-color: ; background-size: cover; background-position: center; min-height: 338px; } #container-1991616823 { border-radius: 6px; } </style> </div> </div> </div> <style type="text/css"> #container-920287546{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-920287546 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn aem-GridColumn--default--12"> <div class="cmp-container-inner " id="container-2139676045"> <div class="aem-Grid aem-Grid--12 aem-Grid--small--12 aem-Grid--default--12 aem-Grid--xsmall--12 aem-Grid--medium--12 "> <div class="cmp-container aem-GridColumn--small--none aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--offset--default--0 aem-GridColumn--offset--medium--0 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--small--11 aem-GridColumn--offset--small--0 aem-GridColumn--default--6"> <div class="cmp-container-inner py-5 " id="container-806531749"> <div class="aem-Grid aem-Grid--6 aem-Grid--small--11 aem-Grid--default--6 aem-Grid--xsmall--12 aem-Grid--medium--12 "> <div class="text aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--small--11 aem-GridColumn--default--6"> <div id="text-50f213bdef" class="cmp-text list-style-bullets"> <h4><b><a href="https://www.patheon.com/us/en/site-locations/swindon-uk.html">Swindon, United Kingdom</a></b></h4> </div> </div> <div class="text aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--small--11 aem-GridColumn--default--6"> <div id="text-19da452104" class="cmp-text list-style-bullets"> <p>Our Swindon facility specializes in integrated sterile liquid and lyophilized product development and commercial manufacturing, including high-potency products and LVP. It offers extensive development and commercial capabilities for sterile dosage forms, including liquid vials, commercial fill-finish lines, and primary and secondary packaging vials.</p> </div> </div> </div> </div> <style type="text/css"> #container-806531749{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-806531749 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--small--none aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--offset--default--0 aem-GridColumn--offset--medium--2 aem-GridColumn--small--8 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--offset--small--2 aem-GridColumn--default--6 aem-GridColumn--medium--8"> <div class="cmp-container-inner ms-md-0 ms-lg-3 " id="container-1513802653"> <div class="aem-Grid aem-Grid--6 aem-Grid--small--8 aem-Grid--default--6 aem-Grid--xsmall--12 aem-Grid--medium--8 "> </div> </div> <style type="text/css"> #container-1513802653{ background-image: url('/content/dam/patheon/global/library/thumbnails/site-locations/site-uk-swindon.jpg'); 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background-color: ; background-size: cover; background-position: center; min-height: px; } #container-80718146 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--small--none aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--12 aem-GridColumn--offset--phone--0 aem-GridColumn--offset--default--0 aem-GridColumn--offset--medium--2 aem-GridColumn--small--8 aem-GridColumn--phone--none aem-GridColumn--xsmall--none aem-GridColumn--phone--10 aem-GridColumn aem-GridColumn--offset--small--2 aem-GridColumn--default--6 aem-GridColumn--medium--8"> <div class="cmp-container-inner ms-lg-3 ms-md-0 " id="container-1375640163"> <div class="aem-Grid aem-Grid--6 aem-Grid--small--8 aem-Grid--default--6 aem-Grid--xsmall--12 aem-Grid--phone--10 aem-Grid--medium--8 "> </div> </div> <style type="text/css"> #container-1375640163{ background-image: url('/content/dam/patheon/global/library/thumbnails/site-locations/singapore-sterile-fill-finish-facility.png'); 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background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1473779332 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn aem-GridColumn--default--12"> <div class="cmp-container-inner py-3 " id="container-469898182"> <div class="aem-Grid aem-Grid--12 aem-Grid--default--12 aem-Grid--xsmall--12 "> <div class="text aem-GridColumn aem-GridColumn--default--12"> <div id="text-04f2bcbd9e" class="cmp-text list-style-bullets"> <h4>Helpful resources</h4> </div> </div> <div class="cmp-container aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--hide aem-GridColumn--xsmall--12 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--default--12 aem-GridColumn--offset--default--0"> <div class="cmp-container-inner " id="container-108373960"> <div class="aem-Grid aem-Grid--12 "> <div class="cmp-container aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--offset--default--0"> <div class="cmp-container-inner py-3 " id="container-1135054308"> <div class="aem-Grid aem-Grid--0 aem-Grid--default--3 aem-Grid--xsmall--3 aem-Grid--medium--3 "> <div class="cmp-library-card aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--medium--3 aem-GridColumn--default--none aem-GridColumn--xsmall--3 aem-GridColumn--xsmall--none aem-GridColumn aem-GridColumn--default--3 aem-GridColumn--offset--default--0"> <div class="library-card imgType-top" id="library_card-1152717827"> <div class="img-and-tag"> <img class="library-card-top-img" src="/content/dam/temp_patheon/library/thumbnails/viral-vector-services/Viral_vector_servicesG.png" alt=""/> <div class="upper-right-tag"> <i class="fak fa-patheon-blog pad-right icon"></i> Blog </div> </div> <div class="library-card-body"> <p class="library-card-preheader"> Blog </p> <p class="library-card-title"> Viral vector commercialization – Part 1: Tech transfer process for commercial viral vector manufacturing </p> <span class="library-card-desc"> <p>Learn how tech transfers can help develop and manufacture viral vectors at scale, accelerate vaccine and gene therapy commercialization, and provide expertise.</p> <ol> </ol> </span> <a href="https://www.patheon.com/us/en/insights-resources/blog/tech-transfers-for-viral-vector-commercialization.html" target="_self" class="btn library-card-btn library-card-primary-btn "> Read Blog </a> </div> </div> </div> </div> </div> <style type="text/css"> #container-1135054308{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1135054308 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--xsmall--newline aem-GridColumn aem-GridColumn--offset--default--0"> <div class="cmp-container-inner py-3 " id="container-1429383733"> <div class="aem-Grid aem-Grid--0 aem-Grid--default--3 aem-Grid--xsmall--3 aem-Grid--medium--3 "> <div class="cmp-library-card aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--medium--3 aem-GridColumn--default--none aem-GridColumn--xsmall--3 aem-GridColumn aem-GridColumn--default--3 aem-GridColumn--offset--default--0"> <div class="library-card imgType-top" id="library_card-2094668620"> <div class="img-and-tag"> <img class="library-card-top-img" src="/content/dam/temp_patheon/library/thumbnails/viral-vector-services/Viral_vector_servicesH.png" alt=""/> <div class="upper-right-tag"> <i class="fak fa-patheon-blog pad-right icon"></i> Blog </div> </div> <div class="library-card-body"> <p class="library-card-preheader"> Blog </p> <p class="library-card-title"> Viral vector commercialization – Part 2: Best practices in process validation lifecycle </p> <span class="library-card-desc"> <p>Learn more about the robust viral vector process validation cycle, which includes various assessments and studies to ensure the safety, efficacy, and quality of viral vectors.</p> <ol> </ol> </span> <a href="https://www.patheon.com/us/en/insights-resources/blog/viral-vector-process-validation.html" target="_self" class="btn library-card-btn library-card-primary-btn "> Read Blog </a> </div> </div> </div> </div> </div> <style type="text/css"> #container-1429383733{ background-image: url(''); background-color: ; background-size: cover; background-position: center; min-height: px; } #container-1429383733 { border-radius: px; } </style> </div> <div class="cmp-container aem-GridColumn--offset--medium--0 aem-GridColumn--offset--xsmall--0 aem-GridColumn--default--none aem-GridColumn--medium--newline aem-GridColumn--xsmall--newline aem-GridColumn--medium--12 aem-GridColumn aem-GridColumn--offset--default--0"> <div class="cmp-container-inner py-3 " id="container-101732411"> <div class="aem-Grid aem-Grid--0 aem-Grid--default--3 aem-Grid--xsmall--3 aem-Grid--medium--3 "> <div class="cmp-library-card aem-GridColumn--offset--medium--0 aem-GridColumn--medium--none aem-GridColumn--default--none aem-GridColumn--xsmall--3 aem-GridColumn aem-GridColumn--default--3 aem-GridColumn--offset--default--0"> <div class="library-card imgType-top" id="library_card-1796300868"> <div class="img-and-tag"> <img class="library-card-top-img" src="/content/dam/temp_patheon/library/thumbnails/viral-vector-services/Viral_vector_servicesG.png" alt=""/> <div class="upper-right-tag"> <i class="fak fa-patheon-article pad-right icon"></i> Article </div> </div> <div class="library-card-body"> <p class="library-card-preheader"> Article </p> <p class="library-card-title"> Strategies to accelerate drug development through harmonization of early and late stage processes </p> <span class="library-card-desc"> <p>This technical article presents a harmonized and streamlined approach established at Thermo Fisher Scientific for manufacturing AAV and LV vectors for discovery research using technologies and processes mirroring current GMP platforms.</p> </span> <a href="https://www.patheon.com/us/en/insights-resources/articles/strategies-to-accelerate-drug-development-through-harmonization-of-early-and-late-stage-processes.html" target="_self" class="btn library-card-btn library-card-primary-btn "> View Article </a> </div> </div> </div> </div> </div> <style type="text/css"> #container-101732411{ background-image: url(''); 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