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bioRxiv: the preprint server for biology | bioRxiv
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This pre-print is available under a Creative Commons License (Attribution 4.0 International), CC BY 4.0, as described at http://creativecommons.org/licenses/by/4.0/" /> <meta name="DC.AccessRights" content="restricted" /> <meta name="DC.Description" content="The traditional publication process delays dissemination of new research, often by months, sometimes by years. Preprint servers decouple dissemination of research papers from their evaluation and certification by journals, allowing researchers to share work immediately, receive feedback from a much larger audience, and provide evidence of productivity long before formal publication. Launched in 2013 as a non-profit community service, the bioRxiv server has brought preprint practice to the life sciences and recently posted its 64,000th manuscript. The server now receives more than four million views per month and hosts papers spanning all areas of biology. Initially dominated by evolutionary biology, genetics/genomics and computational biology, bioRxiv has been increasingly populated by papers in neuroscience, cell and developmental biology, and many other fields. Changes in journal and funder policies that encourage preprint posting have helped drive adoption, as has the development of bioRxiv technologies that allow authors to transfer papers easily between the server and journals. A bioRxiv user survey found that 42% of authors post their preprints prior to journal submission whereas 37% post concurrently with journal submission. Authors are motivated by a desire to share work early; they value the feedback they receive, and very rarely experience any negative consequences of preprint posting. Rapid dissemination via bioRxiv is also encouraging new initiatives that experiment with the peer review process and the development of novel approaches to literature filtering and assessment." /> <meta name="DC.Contributor" content="Richard Sever" /> <meta name="DC.Contributor" content="Ted Roeder" /> <meta name="DC.Contributor" content="Samantha Hindle" /> <meta name="DC.Contributor" content="Linda Sussman" /> <meta name="DC.Contributor" content="Kevin-John Black" /> <meta name="DC.Contributor" content="Janet Argentine" /> <meta name="DC.Contributor" content="Wayne Manos" /> <meta name="DC.Contributor" content="John R. Inglis" /> <meta name="article:published_time" content="2019-11-06" /> <meta name="article:section" content="New Results" /> <meta name="citation_title" content="bioRxiv: the preprint server for biology" /> <meta name="citation_abstract" lang="en" content="<h3>Abstract</h3> <p>The traditional publication process delays dissemination of new research, often by months, sometimes by years. Preprint servers decouple dissemination of research papers from their evaluation and certification by journals, allowing researchers to share work immediately, receive feedback from a much larger audience, and provide evidence of productivity long before formal publication. Launched in 2013 as a non-profit community service, the bioRxiv server has brought preprint practice to the life sciences and recently posted its 64,000th manuscript. The server now receives more than four million views per month and hosts papers spanning all areas of biology. Initially dominated by evolutionary biology, genetics/genomics and computational biology, bioRxiv has been increasingly populated by papers in neuroscience, cell and developmental biology, and many other fields. Changes in journal and funder policies that encourage preprint posting have helped drive adoption, as has the development of bioRxiv technologies that allow authors to transfer papers easily between the server and journals. A bioRxiv user survey found that 42% of authors post their preprints prior to journal submission whereas 37% post concurrently with journal submission. Authors are motivated by a desire to share work early; they value the feedback they receive, and very rarely experience any negative consequences of preprint posting. Rapid dissemination via bioRxiv is also encouraging new initiatives that experiment with the peer review process and the development of novel approaches to literature filtering and assessment.</p>" /> <meta name="citation_journal_title" content="bioRxiv" /> <meta name="citation_publisher" content="Cold Spring Harbor Laboratory" /> <meta name="citation_publication_date" content="2019/01/01" /> <meta name="citation_mjid" content="biorxiv;833400v1" /> <meta name="citation_id" content="833400v1" /> <meta name="citation_public_url" content="https://www.biorxiv.org/content/10.1101/833400v1" /> <meta name="citation_abstract_html_url" content="https://www.biorxiv.org/content/10.1101/833400v1.abstract" /> <meta name="citation_full_html_url" content="https://www.biorxiv.org/content/10.1101/833400v1.full" /> <meta name="citation_pdf_url" content="https://www.biorxiv.org/content/biorxiv/early/2019/11/06/833400.full.pdf" /> <meta name="citation_doi" content="10.1101/833400" /> <meta name="citation_num_pages" content="19" /> <meta name="citation_article_type" content="Article" /> <meta name="citation_section" content="New Results" /> <meta name="citation_firstpage" content="833400" /> <meta name="citation_author" content="Richard Sever" /> <meta name="citation_author_institution" content="Cold Spring Harbor Laboratory" /> <meta name="citation_author_email" content="sever@cshl.edu" /> <meta name="citation_author_email" content="inglis@cshl.edu" /> <meta name="citation_author_orcid" content="http://orcid.org/0000-0001-6478-931X" /> <meta name="citation_author" content="Ted Roeder" /> <meta name="citation_author_institution" content="Cold Spring Harbor Laboratory" /> <meta name="citation_author_orcid" content="http://orcid.org/0000-0001-5499-7203" /> <meta name="citation_author" content="Samantha Hindle" /> <meta name="citation_author_institution" content="Cold Spring Harbor Laboratory" /> <meta name="citation_author_orcid" content="http://orcid.org/0000-0002-3708-3546" /> <meta name="citation_author" content="Linda Sussman" /> <meta name="citation_author_institution" content="Cold Spring Harbor Laboratory" /> <meta name="citation_author" content="Kevin-John Black" /> <meta name="citation_author_institution" content="Cold Spring Harbor Laboratory" /> <meta name="citation_author_orcid" content="http://orcid.org/0000-0003-2468-6441" /> <meta name="citation_author" content="Janet Argentine" /> <meta name="citation_author_institution" content="Cold Spring Harbor Laboratory" /> <meta name="citation_author" content="Wayne Manos" /> <meta name="citation_author_institution" content="Cold Spring Harbor Laboratory" /> <meta name="citation_author" content="John R. Inglis" /> <meta name="citation_author_institution" content="Cold Spring Harbor Laboratory" /> <meta name="citation_author_email" content="sever@cshl.edu" /> <meta name="citation_author_email" content="inglis@cshl.edu" /> <meta name="citation_author_orcid" content="http://orcid.org/0000-0001-8454-3392" /> <meta name="citation_reference" content="Abdil, R. J. and Blekhman (2019) Rxivist.org: Sorting biology preprints using social media and readership metrics PLOS Biol. 1: e3000269." /> <meta name="citation_reference" content="ASAPbio (2018) https://asapbio.org/letter" /> <meta name="citation_reference" content="ASAPbio (2019) https://asapbio.org/university-policies" /> <meta name="citation_reference" content="Bloom, T. (2019) New preprint server for medical research BMJ 365, 2301" /> <meta name="citation_reference" content="Brainard, J. 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(2016) Report of Partial findings from the National Toxicology Program Carcinogenesis Studies of Cell Phone Radiofrequency Radiation in Hsd: Sprague Dawley® SD rats (Whole Body Exposures) bioRxiv doi: https://doi.org/10.1101/055699 version 1 https://www.biorxiv.org/content/10.1101/055699v1" /> <meta name="twitter:title" content="bioRxiv: the preprint server for biology" /> <meta name="twitter:site" content="@biorxivpreprint" /> <meta name="twitter:card" content="summary" /> <meta name="twitter:image" content="https://www.biorxiv.org/sites/default/files/images/biorxiv_logo_homepage7-5-small.png" /> <meta name="twitter:description" content="The traditional publication process delays dissemination of new research, often by months, sometimes by years. Preprint servers decouple dissemination of research papers from their evaluation and certification by journals, allowing researchers to share work immediately, receive feedback from a much larger audience, and provide evidence of productivity long before formal publication. Launched in 2013 as a non-profit community service, the bioRxiv server has brought preprint practice to the life sciences and recently posted its 64,000th manuscript. The server now receives more than four million views per month and hosts papers spanning all areas of biology. Initially dominated by evolutionary biology, genetics/genomics and computational biology, bioRxiv has been increasingly populated by papers in neuroscience, cell and developmental biology, and many other fields. Changes in journal and funder policies that encourage preprint posting have helped drive adoption, as has the development of bioRxiv technologies that allow authors to transfer papers easily between the server and journals. A bioRxiv user survey found that 42% of authors post their preprints prior to journal submission whereas 37% post concurrently with journal submission. Authors are motivated by a desire to share work early; they value the feedback they receive, and very rarely experience any negative consequences of preprint posting. Rapid dissemination via bioRxiv is also encouraging new initiatives that experiment with the peer review process and the development of novel approaches to literature filtering and assessment." /> <meta name="og-title" property="og:title" content="bioRxiv: the preprint server for biology" /> <meta name="og-url" property="og:url" content="https://www.biorxiv.org/content/10.1101/833400v1" /> <meta name="og-site-name" property="og:site_name" content="bioRxiv" /> <meta name="og-description" property="og:description" content="The traditional publication process delays dissemination of new research, often by months, sometimes by years. Preprint servers decouple dissemination of research papers from their evaluation and certification by journals, allowing researchers to share work immediately, receive feedback from a much larger audience, and provide evidence of productivity long before formal publication. Launched in 2013 as a non-profit community service, the bioRxiv server has brought preprint practice to the life sciences and recently posted its 64,000th manuscript. The server now receives more than four million views per month and hosts papers spanning all areas of biology. Initially dominated by evolutionary biology, genetics/genomics and computational biology, bioRxiv has been increasingly populated by papers in neuroscience, cell and developmental biology, and many other fields. Changes in journal and funder policies that encourage preprint posting have helped drive adoption, as has the development of bioRxiv technologies that allow authors to transfer papers easily between the server and journals. A bioRxiv user survey found that 42% of authors post their preprints prior to journal submission whereas 37% post concurrently with journal submission. Authors are motivated by a desire to share work early; they value the feedback they receive, and very rarely experience any negative consequences of preprint posting. Rapid dissemination via bioRxiv is also encouraging new initiatives that experiment with the peer review process and the development of novel approaches to literature filtering and assessment." /> <meta name="og-type" property="og:type" content="article" /> <meta name="og-image" property="og:image" content="https://www.biorxiv.org/sites/default/files/images/biorxiv_logo_homepage7-5-small.png" /> <meta name="citation_date" content="2019-11-06" /> <link rel="alternate" type="application/vnd.ms-powerpoint" title="Powerpoint" href="/content/10.1101/833400v1.ppt" /> <meta name="description" content="bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution" /> <meta name="generator" content="Drupal 7 (http://drupal.org)" /> <link rel="canonical" href="https://www.biorxiv.org/content/10.1101/833400v1" /> <link rel="shortlink" href="https://www.biorxiv.org/node/982721" /> <title>bioRxiv: the preprint server for biology | 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data-hw-author-tooltip-instance="highwire_author_tooltip"><div class="highwire-cite highwire-cite-highwire-article highwire-citation-biorxiv-article-top clearfix has-author-tooltip" > <span class="biorxiv-article-type"> New Results </span> <h1 class="highwire-cite-title" id="page-title">bioRxiv: the preprint server for biology</h1> <div class="highwire-cite-authors" ><span class="highwire-citation-authors"><span class="highwire-citation-author first hw-author-orcid-logo-wrapper" data-delta="0"><a href="http://orcid.org/0000-0001-6478-931X" target="_blank" class="hw-author-orcid-logo link-icon-only link-icon"><span class="hw-icon-orcid hw-icon-color-orcid"></span> <span class="title element-invisible">View ORCID Profile</span></a><span class="nlm-given-names">Richard</span> <span class="nlm-surname">Sever</span></span>, <span class="highwire-citation-author hw-author-orcid-logo-wrapper" data-delta="1"><a href="http://orcid.org/0000-0001-5499-7203" target="_blank" class="hw-author-orcid-logo link-icon-only link-icon"><span class="hw-icon-orcid hw-icon-color-orcid"></span> <span class="title element-invisible">View ORCID Profile</span></a><span class="nlm-given-names">Ted</span> <span class="nlm-surname">Roeder</span></span>, <span class="highwire-citation-author hw-author-orcid-logo-wrapper" data-delta="2"><a href="http://orcid.org/0000-0002-3708-3546" target="_blank" class="hw-author-orcid-logo link-icon-only link-icon"><span class="hw-icon-orcid hw-icon-color-orcid"></span> <span class="title element-invisible">View ORCID Profile</span></a><span class="nlm-given-names">Samantha</span> <span class="nlm-surname">Hindle</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">Linda</span> <span class="nlm-surname">Sussman</span></span>, <span class="highwire-citation-author hw-author-orcid-logo-wrapper" data-delta="4"><a href="http://orcid.org/0000-0003-2468-6441" target="_blank" class="hw-author-orcid-logo link-icon-only link-icon"><span class="hw-icon-orcid hw-icon-color-orcid"></span> <span class="title element-invisible">View ORCID Profile</span></a><span class="nlm-given-names">Kevin-John</span> <span class="nlm-surname">Black</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">Janet</span> <span class="nlm-surname">Argentine</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">Wayne</span> <span class="nlm-surname">Manos</span></span>, <span class="highwire-citation-author hw-author-orcid-logo-wrapper" data-delta="7"><a href="http://orcid.org/0000-0001-8454-3392" target="_blank" class="hw-author-orcid-logo link-icon-only link-icon"><span class="hw-icon-orcid hw-icon-color-orcid"></span> <span class="title element-invisible">View ORCID Profile</span></a><span class="nlm-given-names">John R.</span> <span class="nlm-surname">Inglis</span></span></span></div> <div class="highwire-cite-metadata" ><span class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">doi:</span> https://doi.org/10.1101/833400 </span></div> </div> <div id="hw-article-author-popups-node-982721--2696518598" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">Richard Sever </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-institution'>Cold Spring Harbor Laboratory</span>, 1 Bungtown Road, Cold Spring Harbor, New York, <span class='nlm-country'>USA</span></div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&gs_type=author&author%5B0%5D=Richard%2BSever%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Sever%20R&link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3ARichard%2BSever%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link"><a href="http://orcid.org/0000-0001-6478-931X" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Richard Sever</a></li><li class="author-corresp-email-link last"><span>For correspondence: <a href="/cdn-cgi/l/email-protection#1a697f6c7f685a79697276347f7e6f" class="" data-icon-position="" data-hide-link-title="0"><span class="__cf_email__" data-cfemail="700315061502301303181c5e151405">[email protected]</span></a> <a href="/cdn-cgi/l/email-protection#3851565f54514b785b4b5054165d5c4d" class="" data-icon-position="" data-hide-link-title="0"><span class="__cf_email__" data-cfemail="84edeae3e8edf7c4e7f7ece8aae1e0f1">[email protected]</span></a></span></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">Ted Roeder </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-institution'>Cold Spring Harbor Laboratory</span>, 1 Bungtown Road, Cold Spring Harbor, New York, <span class='nlm-country'>USA</span></div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&gs_type=author&author%5B0%5D=Ted%2BRoeder%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Roeder%20T&link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li 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data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Hindle%20S&link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3ASamantha%2BHindle%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="http://orcid.org/0000-0002-3708-3546" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Samantha Hindle</a></li></ul></div><div class="author-tooltip-3"><div class="author-tooltip-name">Linda Sussman </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-institution'>Cold Spring Harbor Laboratory</span>, 1 Bungtown Road, Cold Spring Harbor, New York, <span class='nlm-country'>USA</span></div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&gs_type=author&author%5B0%5D=Linda%2BSussman%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Sussman%20L&link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3ALinda%2BSussman%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-4"><div class="author-tooltip-name">Kevin-John Black </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-institution'>Cold Spring Harbor Laboratory</span>, 1 Bungtown Road, Cold Spring Harbor, New York, <span class='nlm-country'>USA</span></div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&gs_type=author&author%5B0%5D=Kevin-John%2BBlack%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Black%20K&link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AKevin-John%2BBlack%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="http://orcid.org/0000-0003-2468-6441" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for Kevin-John Black</a></li></ul></div><div class="author-tooltip-5"><div class="author-tooltip-name">Janet Argentine </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-institution'>Cold Spring Harbor Laboratory</span>, 1 Bungtown Road, Cold Spring Harbor, New York, <span class='nlm-country'>USA</span></div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&gs_type=author&author%5B0%5D=Janet%2BArgentine%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Argentine%20J&link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AJanet%2BArgentine%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-6"><div class="author-tooltip-name">Wayne Manos </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-institution'>Cold Spring Harbor Laboratory</span>, 1 Bungtown Road, Cold Spring Harbor, New York, <span class='nlm-country'>USA</span></div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&gs_type=author&author%5B0%5D=Wayne%2BManos%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Manos%20W&link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AWayne%2BManos%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-7"><div class="author-tooltip-name">John R. Inglis </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-institution'>Cold Spring Harbor Laboratory</span>, 1 Bungtown Road, Cold Spring Harbor, New York, <span class='nlm-country'>USA</span></div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&gs_type=author&author%5B0%5D=John%2BR.%2BInglis%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Inglis%20JR&link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AJohn%2BR.%2BInglis%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link"><a href="http://orcid.org/0000-0001-8454-3392" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for John R. 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