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Prospective evaluation of point-of-care ultrasonography for the diagnosis of pneumonia in children and young adults - PubMed

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"><a class="full-name" href="/?term=Shah+VP&amp;cauthor_id=23229753" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Vaishali P Shah">Vaishali P Shah</a><sup class="affiliation-links"><span class="author-sup-separator">&nbsp;</span><a class="affiliation-link" title="Department of Emergency Medicine, Children&#x27;s Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, NY, USA." href="#full-view-affiliation-1" ref="linksrc=author_aff"> 1 </a></sup><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name" href="/?term=Tunik+MG&amp;cauthor_id=23229753" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Michael G Tunik">Michael G Tunik</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name" href="/?term=Tsung+JW&amp;cauthor_id=23229753" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="James W Tsung">James W Tsung</a></span> </div> </div> </div> <div class="short-article-details"> Affiliations <button class="more-details" id="toggle-authors" data-alt-text="Collapse" aria-controls="expanded-authors" aria-expanded="false" data-pinger-ignore data-fetch-url="/23229753/long-authors/" data-id-prefix=""> <span class="title"> Expand </span> </button> </div> <div class="extended-article-details" id="expanded-authors" aria-hidden="true"> <div class="expanded-authors" id="full-view-expanded-authors"> <div class="affiliations"> <h3 class="title"> Affiliation </h3> <ul class="item-list"> <li data-affiliation-id="full-view-affiliation-1" id="full-view-affiliation-1" ><sup class="key">1</sup> Department of Emergency Medicine, Children&#x27;s Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, NY, USA.</li> </ul> </div> </div> </div> <ul class="identifiers" id="full-view-identifiers"> <li> <span class="identifier pubmed"> <span class="id-label"> PMID: </span> <strong class="current-id" title="PubMed ID">23229753</strong> </span> </li> <li> <span class="identifier doi"> <span class="id-label"> DOI: </span> <a class="id-link" target="_blank" rel="noopener" ref="linksrc=article_id_link&amp;article_id=10.1001/2013.jamapediatrics.107&amp;id_type=DOI" href="https://doi.org/10.1001/2013.jamapediatrics.107" data-ga-category="full_text" data-ga-action="DOI" > 10.1001/2013.jamapediatrics.107 </a> </span> </li> </ul> <div class="in-clipboard-label " hidden> Item in Clipboard </div> </div> <div class="short-view" id="short-view-heading"> <div class="publication-type" >Clinical Trial</div> <h1 class="heading-title"> Prospective evaluation of point-of-care ultrasonography for the diagnosis of pneumonia in children and young adults </h1> <div class="short-citation"> <span class="authors-list"> <span class="authors-list-item "><span class="full-name">Vaishali P Shah</span><span class="citation-separator">&nbsp;et al.</span></span> </span> <span class="citation-journal"> JAMA Pediatr<span class="citation-separator">.</span> </span> <span class="date"> <span class="citation-year">2013 Feb</span><span class="citation-separator">.</span> </span> </div> <div class="more-article-details-section with-display-settings"> <button class="more-article-details" id="toggle-article-details" data-alt-text="Hide details" ref="linksrc=toggle_article_details" aria-controls="full-article-details" aria-expanded="false" data-fetch-url="/23229753/long-authors/" data-id-prefix=""> <span class="title">Show details</span> </button> <div class="display-options" data-format-key="format" data-default-format-value="abstract" data-current-format-value="abstract" role="region"> <button class="trigger usa-button" title="Change format" data-ga-category="display_options" data-ga-action="display_options_dialog"> <span class="button-label">Display options</span> </button> <div class="dropdown" hidden> <div class="title"> Display 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1 </a></sup><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name" href="/?term=Tunik+MG&amp;cauthor_id=23229753" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Michael G Tunik">Michael G Tunik</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name" href="/?term=Tsung+JW&amp;cauthor_id=23229753" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="James W Tsung">James W Tsung</a></span> </div> </div> <div class="affiliations"> <h3 class="title"> Affiliation </h3> <ul class="item-list"> <li data-affiliation-id="short-view-affiliation-1" id="short-view-affiliation-1" ><sup class="key">1</sup> Department of Emergency Medicine, Children&#x27;s Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, NY, USA.</li> </ul> </div> </div> <ul class="identifiers" id="short-view-identifiers"> <li> <span class="identifier pubmed"> <span class="id-label"> PMID: </span> <strong class="current-id" title="PubMed ID">23229753</strong> </span> </li> <li> <span class="identifier doi"> <span class="id-label"> DOI: </span> <a class="id-link" target="_blank" rel="noopener" ref="linksrc=article_id_link&amp;article_id=10.1001/2013.jamapediatrics.107&amp;id_type=DOI" href="https://doi.org/10.1001/2013.jamapediatrics.107" data-ga-category="full_text" data-ga-action="DOI" > 10.1001/2013.jamapediatrics.107 </a> </span> </li> </ul> <div class="in-clipboard-label " hidden> Item in Clipboard </div> </div> </div> </header> <div class="actions-buttons inline"><div class="inner-wrap"><button class="full-text-links-button full-text-links-dialog-trigger" title="Open dialog with full text links" ref="linksrc=full_text_links"> Full text links </button><button class="citation-button citation-dialog-trigger" aria-label="Open dialog with citation text in different styles" data-ga-category="save_share" 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value="abstract">Abstract</option><option value="pubmed">PubMed</option><option value="pmid">PMID</option></select></div></div></div></div></div></div> <div class="abstract" id="abstract"> <h2 class="title"> Abstract </h2> <div class="abstract-content selected" id="eng-abstract"> <p> <strong class="sub-title"> Objective: </strong> To determine the accuracy of point-of-care ultrasonography for the diagnosis of pneumonia in children and young adults by a group of clinicians. </p> <p> <strong class="sub-title"> Design: </strong> Prospective observational cohort study. </p> <p> <strong class="sub-title"> Setting: </strong> Two urban emergency departments. </p> <p> <strong class="sub-title"> Participants: </strong> Patients from birth to age 21 years undergoing chest radiography for suspected community-acquired pneumonia. </p> <p> <strong class="sub-title"> Intervention: </strong> After documenting clinical examination findings, clinicians with 1 hour of focused training used ultrasonography to diagnose pneumonia in children and young adults. </p> <p> <strong class="sub-title"> Main outcomes measures: </strong> Test performance characteristics for the ability of ultrasonography to diagnose pneumonia were determined using chest radiography as a reference standard. Subgroup analysis was performed in patients having lung consolidation exceeding 1 cm with sonographic air bronchograms detected on ultrasonography; specificity and positive likelihood ratio (LR) were calculated to account for lung consolidation of 1 cm or less with sonographic air bronchograms undetectable by chest radiography. </p> <p> <strong class="sub-title"> Results: </strong> Two hundred patients were studied (median age, 3 years; interquartile range, 1-8 years); 56.0% were male, and the prevalence of pneumonia by chest radiography was 18.0%. Ultrasonography had an overall sensitivity of 86% (95% CI, 71%-94%), specificity of 89% (95% CI, 83%-93%), positive LR of 7.8 (95% CI, 5.0-12.4), and negative LR of 0.2 (95% CI, 0.1-0.4) for diagnosing pneumonia by visualizing lung consolidation with sonographic air bronchograms. In subgroup analysis of 187 patients having lung consolidation exceeding 1 cm, ultrasonography had a sensitivity of 86% (95% CI, 71%-94%), specificity of 97% (95% CI, 93%-99%), positive LR of 28.2 (95% CI, 11.8-67.6) and negative LR of 0.1 (95% CI, 0.1-0.3) for diagnosing pneumonia. </p> <p> <strong class="sub-title"> Conclusion: </strong> Clinicians are able to diagnose pneumonia in children and young adults using point-of-care ultrasonography, with high specificity. </p> </div> </div> <p class="disclaimer" id="disclaimer"> <a href="/disclaimer/" target="_blank" ga_category="literature_resources" ga_action="disclaimer_link" ga_label="under_abstract">PubMed Disclaimer</a> </p> <div class="linked-articles" id="linked-commentary"> <h2 class="title"> Comment in </h2> <ul class="item-list usa-unstyled-list"> <li class="full-docsum"> <div class="docsum-content" style="display:inline;"> <a class="docsum-title" href="/23229804/" ref="article_id=23229804&amp;linksrc=comments_link" data-ga-category="comment_correction" data-ga-action="abstract_page_link" data-ga-label="linked-commentary"> Ultrasonography of the lungs and pleurae for the diagnosis of pneumonia in children: prime time for routine use. </a> <div class="docsum-citation full-citation"> <span class="docsum-authors full-authors">Darge K, Chen A.</span> <span class="docsum-authors short-authors">Darge K, et al.</span> <span class="docsum-journal-citation full-journal-citation">JAMA Pediatr. 2013 Feb;167(2):187-8. doi: 10.1001/2013.jamapediatrics.409.</span> <span class="docsum-journal-citation short-journal-citation">JAMA Pediatr. 2013.</span> <span class="citation-part">PMID: <span class="docsum-pmid">23229804</span></span> <span class="no-abstract spaced-citation-item citation-part">No abstract available.</span> </div> </div> </li> <li class="full-docsum"> <div class="docsum-content" style="display:inline;"> <a class="docsum-title" href="/23796342/" ref="article_id=23796342&amp;linksrc=comments_link" data-ga-category="comment_correction" data-ga-action="abstract_page_link" data-ga-label="linked-commentary"> Point-of-care ultrasound in diagnosing pneumonia in children. </a> <div class="docsum-citation full-citation"> <span class="docsum-authors full-authors">Darge K, Chen A.</span> <span class="docsum-authors short-authors">Darge K, et al.</span> <span class="docsum-journal-citation full-journal-citation">J Pediatr. 2013 Jul;163(1):302-3. doi: 10.1016/j.jpeds.2013.04.059.</span> <span class="docsum-journal-citation short-journal-citation">J Pediatr. 2013.</span> <span class="citation-part">PMID: <span class="docsum-pmid">23796342</span></span> <span class="no-abstract spaced-citation-item citation-part">No abstract available.</span> </div> </div> </li> </ul> </div> <div class="similar-articles" id="similar"> <h2 class="title"> Similar articles </h2> <ul class="articles-list" id="similar-articles-list"> <li class="full-docsum"> <div class="docsum-content" style="display:inline;"> <a class="docsum-title" href="/27536810/" ref="article_id=27536810&amp;linksrc=similar_articles_link&amp;ordinalpos=1" data-ga-category="similar_article" data-ga-action="27536810" data-ga-label=""> Prospective evaluation of clinical lung ultrasonography in the diagnosis of community-acquired pneumonia in a pediatric emergency department. </a> <div class="docsum-citation full-citation"> <span class="docsum-authors full-authors">Samson F, Gorostiza I, Gonz谩lez A, Landa M, Ruiz L, Grau M.</span> <span class="docsum-authors short-authors">Samson F, et al.</span> <span class="docsum-journal-citation full-journal-citation">Eur J Emerg Med. 2018 Feb;25(1):65-70. doi: 10.1097/MEJ.0000000000000418.</span> <span class="docsum-journal-citation short-journal-citation">Eur J Emerg Med. 2018.</span> <span class="citation-part">PMID: <span class="docsum-pmid">27536810</span></span> </div> </div> </li> <li class="full-docsum"> <div class="docsum-content" style="display:inline;"> <a class="docsum-title" href="/28202294/" ref="article_id=28202294&amp;linksrc=similar_articles_link&amp;ordinalpos=2" data-ga-category="similar_article" data-ga-action="28202294" data-ga-label=""> Point-of-care lung ultrasound in children with community acquired pneumonia. </a> <div class="docsum-citation full-citation"> <span class="docsum-authors full-authors">Yilmaz HL, 脰zkaya AK, Sar谋 G枚kay S, Tolu Kendir 脰, 艦enol H.</span> <span class="docsum-authors short-authors">Yilmaz HL, et al.</span> <span class="docsum-journal-citation full-journal-citation">Am J Emerg Med. 2017 Jul;35(7):964-969. doi: 10.1016/j.ajem.2017.01.065. 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